725e02e33261c8f77b2c72bf094254cd  pmc_26876667.pdf
4e0944a0f6a32f862a729eabf5b7f746ce502dfa  pmc_26876667.pdf
e08307c13c0370ccbeea91b7b40aab4495a9cc1c3c0392ab3c0115d41806ffb7  pmc_26876667.pdf

Title:          Oncometabolic Nuclear Reprogramming of Cancer Stemness
Subject:        Stem Cell Reports, 6 (2016) 273-283. doi:10.1016/j.stemcr.2015.12.012
Author:         Javier A. Menendez
Creator:        Elsevier
Producer:       Acrobat Distiller 8.1.0 (Windows)
CreationDate:   Tue Dec 31 23:45:16 2 LMT
ModDate:        Thu Mar  3 15:57:33 2016 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          11
Encrypted:      no
Page size:      602.986 x 782.986 pts
Page rot:       0
File size:      2541663 bytes
Optimized:      yes
PDF version:    1.7

name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
DHCBIG+AdvPS8E94                     Type 1C           WinAnsi          yes yes no     788  0
DHCBJG+AdvPS8E82                     Type 1C           WinAnsi          yes yes no     792  0
DHCBJH+AdvPS8E9A                     Type 1C           WinAnsi          yes yes no     794  0
DHCBJI+AdvP9725                      Type 1C           MacRoman         yes yes no     796  0
DHCBKJ+AdvPS9788                     Type 1C           WinAnsi          yes yes no     799  0
DHCBKK+AdvP9794                      Type 1C           WinAnsi          yes yes no     803  0
DHCBLK+AdvPS8E91                     Type 1C           WinAnsi          yes yes no     812  0
DHCBLL+AdvP4C4E74                    Type 1C           Custom           yes yes yes    808  0
DHCBLM+AdvPSSym                      Type 1C           WinAnsi          yes yes no     810  0
DHCEGO+AdvPSA06A                     Type 1C           WinAnsi          yes yes no     547  0
DHCEHO+AdvPS3F4C13                   Type 1C           WinAnsi          yes yes no     545  0
DHCEHP+AdvP7DED                      Type 1C           WinAnsi          yes yes no     551  0
DHCEGM+AdvPSA05F                     Type 1C           WinAnsi          yes yes no     554  0
DHCEGN+AdvPSA066                     Type 1C           Custom           yes yes no     548  0
DHCEKA+AdvPS4721B4                   Type 1C           WinAnsi          yes yes no     563  0
DHCGHF+AdvHelN-L                     Type 1C           WinAnsi          yes yes no     568  0
DHCIKH+AdvP9797                      Type 1C           WinAnsi          yes yes no     576  0
DHCKAP+AdvPS4731B1                   Type 1C           WinAnsi          yes yes no     582  0

Jhove (Rel. 1.6, 2011-01-04)
 Date: 2018-05-16 04:37:24 CEST
 RepresentationInformation: pmc_26876667.pdf
  ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22)
  LastModified: 2018-02-06 09:10:08 CET
  Size: 2541663
  Format: PDF
  Version: 1.7
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ErrorMessage: Improperly formed date
   Offset: 2527370
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2513492
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  ErrorMessage: Invalid destination object
   Offset: 2512522
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 869
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Oncometabolic Nuclear Reprogramming of Cancer Stemness
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7c53a9eb
      Children: 
       Item: 
        Title: Introduction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed17bee
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2a33fae0
       Item: 
        Title: Discussion
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@707f7052
       Item: 
        Title: Experimental Procedures
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11028347
        Children: 
         Item: 
          Title: Stochastic Model
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@14899482
         Item: 
          Title: Reagents
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809
         Item: 
          Title: Cell Lines
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190
         Item: 
          Title: Reprogramming of Human Breast Epithelial Cells and Cell Infection
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739
         Item: 
          Title: Alkaline Phosphatase Staining
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9
         Item: 
          Title: Live Staining by the TRA-1-60 Antibody
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8
         Item: 
          Title: Histone Extraction and Western Analysis
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e
         Item: 
          Title: Targeted Metabolomics
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070
         Item: 
          Title: Global DNA Methylation
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5
         Item: 
          Title: Genome-wide DNA Methylation: DNA Methylation Microarrays and Data Analysis
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4
         Item: 
          Title: Multivariate Permeabilized Cell Flow Cytometry
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1
       Item: 
        Title: Accession Numbers
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc
       Item: 
        Title: Supplemental Information
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1f89ab83
       Item: 
        Title: Author Contributions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e73f9ac
       Item: 
        Title: Acknowledgments
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@61064425
       Item: 
        Title: References
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b1d7fff
   Info: 
    Title: Oncometabolic Nuclear Reprogramming of Cancer Stemness
    Author: Javier A. Menendez
    Subject: Stem Cell Reports, 6 (2016) 273-283. doi:10.1016/j.stemcr.2015.12.012
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
   ID: 0x4b44d801a23e0417c3a0f6daaa945da4, 0x313a8fcefe60d1428e1b5d724580ad9a
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 83
      ImageHeight: 83
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1335
      ImageHeight: 2474
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1343
      ImageHeight: 1574
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1717
      ImageHeight: 1419
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1335
      ImageHeight: 1189
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
   Fonts: 
    Type1: 
     Font: 
      BaseFont: DHCIKH+AdvP9797
      FontSubset: true
      FirstChar: 45
      LastChar: 122
      FontDescriptor: 
       FontName: DHCIKH+AdvP9797
       Flags: Serif, Nonsymbolic
       FontBBox: -187, -250, 1312, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEHO+AdvPS3F4C13
      FontSubset: true
      FirstChar: 97
      LastChar: 119
      FontDescriptor: 
       FontName: DHCEHO+AdvPS3F4C13
       Flags: Nonsymbolic
       FontBBox: 0, -291, 875, 697
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBKK+AdvP9794
      FontSubset: true
      FirstChar: 45
      LastChar: 121
      FontDescriptor: 
       FontName: DHCBKK+AdvP9794
       Flags: Nonsymbolic
       FontBBox: -208, -250, 1291, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEGO+AdvPSA06A
      FontSubset: true
      FirstChar: 40
      LastChar: 122
      FontDescriptor: 
       FontName: DHCEGO+AdvPSA06A
       Flags: Nonsymbolic
       FontBBox: -156, -239, 1031, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEGN+AdvPSA066
      FontSubset: true
      FirstChar: 30
      LastChar: 150
      FontDescriptor: 
       FontName: DHCEGN+AdvPSA066
       Flags: Nonsymbolic
       FontBBox: -72, -239, 1052, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: DHCKAP+AdvPS4731B1
      FontSubset: true
      FirstChar: 82
      LastChar: 82
      FontDescriptor: 
       FontName: DHCKAP+AdvPS4731B1
       Flags: Nonsymbolic
       FontBBox: 0, -208, 1572, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEHP+AdvP7DED
      FontSubset: true
      FirstChar: 51
      LastChar: 51
      FontDescriptor: 
       FontName: DHCEHP+AdvP7DED
       Flags: Nonsymbolic
       FontBBox: -20, -229, 927, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBLL+AdvP4C4E74
      FontSubset: true
      FirstChar: 2
      LastChar: 106
      FontDescriptor: 
       FontName: DHCBLL+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DHCBLM+AdvPSSym
      FontSubset: true
      FirstChar: 170
      LastChar: 170
      FontDescriptor: 
       FontName: DHCBLM+AdvPSSym
       Flags: Nonsymbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEGM+AdvPSA05F
      FontSubset: true
      FirstChar: 44
      LastChar: 121
      FontDescriptor: 
       FontName: DHCEGM+AdvPSA05F
       Flags: Nonsymbolic
       FontBBox: -52, -250, 1135, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBLK+AdvPS8E91
      FontSubset: true
      FirstChar: 67
      LastChar: 116
      FontDescriptor: 
       FontName: DHCBLK+AdvPS8E91
       Flags: Nonsymbolic
       FontBBox: -197, -239, 1000, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCEKA+AdvPS4721B4
      FontSubset: true
      FirstChar: 119
      LastChar: 119
      FontDescriptor: 
       FontName: DHCEKA+AdvPS4721B4
       Flags: Nonsymbolic
       FontBBox: 0, -208, 843, 697
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBIG+AdvPS8E94
      FontSubset: true
      FirstChar: 67
      LastChar: 116
      FontDescriptor: 
       FontName: DHCBIG+AdvPS8E94
       Flags: Nonsymbolic
       FontBBox: -208, -239, 1031, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBJG+AdvPS8E82
      FontSubset: true
      FirstChar: 48
      LastChar: 116
      FontDescriptor: 
       FontName: DHCBJG+AdvPS8E82
       Flags: Nonsymbolic
       FontBBox: -166, -239, 1166, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCGHF+AdvHelN-L
      FontSubset: true
      FirstChar: 177
      LastChar: 177
      FontDescriptor: 
       FontName: DHCGHF+AdvHelN-L
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1041, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBJH+AdvPS8E9A
      FontSubset: true
      FirstChar: 44
      LastChar: 150
      FontDescriptor: 
       FontName: DHCBJH+AdvPS8E9A
       Flags: Nonsymbolic
       FontBBox: -156, -239, 1041, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DHCBJI+AdvP9725
      FontSubset: true
      FirstChar: 35
      LastChar: 252
      FontDescriptor: 
       FontName: DHCBJI+AdvP9725
       Flags: Serif, Nonsymbolic
       FontBBox: -197, -239, 1270, 770
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: DHCBKJ+AdvPS9788
      FontSubset: true
      FirstChar: 65
      LastChar: 89
      FontDescriptor: 
       FontName: DHCBKJ+AdvPS9788
       Flags: Nonsymbolic
       FontBBox: -177, -239, 1395, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 4.0-c316 44.253921, Sun Oct 01 2006 17:14:39">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1016/j.stemcr.2015.12.012</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Oncometabolic Nuclear Reprogramming of Cancer Stemness</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Javier A. Menendez</rdf:li>
               <rdf:li>Bruna Corominas-Faja</rdf:li>
               <rdf:li>Elisabet Cuyàs</rdf:li>
               <rdf:li>María G. García</rdf:li>
               <rdf:li>Salvador Fernández-Arroyo</rdf:li>
               <rdf:li>Agustín F. Fernández</rdf:li>
               <rdf:li>Jorge Joven</rdf:li>
               <rdf:li>Mario F. Fraga</rdf:li>
               <rdf:li>Tomás Alarcón</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Oncometabolites</rdf:li>
               <rdf:li>reprogramming</rdf:li>
               <rdf:li>stemness</rdf:li>
               <rdf:li>cancer</rdf:li>
               <rdf:li>stem cells</rdf:li>
               <rdf:li>cancer stem cells</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Stem Cell Reports, 6 (2016) 273-283. doi:10.1016/j.stemcr.2015.12.012</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier Ltd</rdf:li>
            </rdf:Bag>
         </dc:publisher>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Stem Cell Reports</prism:publicationName>
         <prism:copyright>©2016 The Authors</prism:copyright>
         <prism:issn>2213-6711</prism:issn>
         <prism:volume>6</prism:volume>
         <prism:number>3</prism:number>
         <prism:coverDisplayDate>8 March 2016</prism:coverDisplayDate>
         <prism:coverDate>2016-03-08</prism:coverDate>
         <prism:pageRange>273-283</prism:pageRange>
         <prism:startingPage>273</prism:startingPage>
         <prism:endingPage>283</prism:endingPage>
         <prism:doi>10.1016/j.stemcr.2015.12.012</prism:doi>
         <prism:url>http://dx.doi.org/10.1016/j.stemcr.2015.12.012</prism:url>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1016/j.stemcr.2015.12.012</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:ElsevierWebPDFSpecifications>6.5</pdfx:ElsevierWebPDFSpecifications>
         <pdfx:doi>10.1016/j.stemcr.2015.12.012</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:CreationDate--Text>3th March 2016</pdfx:CreationDate--Text>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>sciencedirect.com</rdf:li>
               <rdf:li>elsevier.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xap="http://ns.adobe.com/xap/1.0/">
         <xap:CreatorTool>Elsevier</xap:CreatorTool>
         <xap:ModifyDate>2016-03-03T20:27:33+05:30</xap:ModifyDate>
         <xap:MetadataDate>2016-03-03T20:27:33+05:30</xap:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapRights="http://ns.adobe.com/xap/1.0/rights/">
         <xapRights:Marked>True</xapRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:CreationDate--Text>3th March 2016</pdf:CreationDate--Text>
         <pdf:Producer>Acrobat Distiller 8.1.0 (Windows)</pdf:Producer>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapMM="http://ns.adobe.com/xap/1.0/mm/">
         <xapMM:DocumentID>uuid:7d84b969-060c-4dcd-9dea-203df248ea21</xapMM:DocumentID>
         <xapMM:InstanceID>uuid:68f8efa5-e2b1-43b3-baad-58a8b1157362</xapMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/by-nc-nd/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 273
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 144, 643, 148, 653
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 150, 643, 155, 653
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 157, 643, 165, 653
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 168, 643, 172, 653
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 280, 643, 284, 653
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 355, 643, 360, 653
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 437, 646, 442, 656
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 179, 631, 183, 641
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 284, 631, 288, 641
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 346, 631, 350, 641
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 420, 631, 424, 641
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 426, 634, 430, 644
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 141, 619, 145, 629
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 147, 619, 151, 629
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 154, 619, 158, 629
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 160, 619, 164, 629
       Destination: 715
      Annotation: 
       Subtype: Link
       Rect: 166, 619, 175, 629
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 177, 619, 181, 629
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 112, 494, 202, 501
      Annotation: 
       Subtype: Link
       Rect: 233, 494, 288, 501
      Annotation: 
       Subtype: Link
       Rect: 55, 485, 207, 492
      Annotation: 
       Subtype: Link
       Rect: 255, 476, 420, 483
      Annotation: 
       Subtype: Link
       Rect: 262, 208, 292, 217
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 53, 196, 292, 205
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 53, 185, 190, 194
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 230, 137, 292, 146
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 125, 260, 134
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 342, 197, 543, 206
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 185, 543, 194
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 173, 543, 182
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 161, 375, 170
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 362, 114, 450, 122
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 352, 66, 543, 75
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 54, 532, 63
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 53, 13, 98, 32
    Page: 
     Label: 274
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 518, 457, 549, 466
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 395, 446, 485, 455
       Destination: null
    Page: 
     Label: 275
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 207, 615, 292, 624
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 603, 286, 612
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 208, 567, 292, 576
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 555, 230, 564
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 74, 388, 187, 397
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 276, 352, 292, 361
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 340, 99, 349
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 108, 340, 142, 349
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 196, 304, 273, 313
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 281, 245, 292, 254
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 233, 205, 242
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 474, 663, 508, 672
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 528, 591, 543, 600
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 304, 579, 325, 588
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 453, 508, 543, 517
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 304, 496, 327, 505
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 333, 436, 442, 445
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 341, 364, 376, 373
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 382, 328, 416, 337
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 512, 304, 543, 313
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 304, 292, 387, 301
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 439, 245, 472, 254
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 203, 173, 234, 182
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 240, 173, 332, 182
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 306, 97, 400, 106
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 53, 83, 62
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 89, 53, 180, 62
       Destination: null
    Page: 
     Label: 276
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 165, 579, 199, 588
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 241, 424, 298, 433
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 59, 412, 108, 421
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 154, 340, 186, 349
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 68, 304, 178, 313
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 84, 197, 167, 206
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 188, 149, 222, 158
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 195, 53, 229, 62
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 466, 651, 549, 660
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 310, 639, 370, 648
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 535, 520, 549, 529
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 310, 508, 334, 517
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 535, 388, 549, 397
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 310, 376, 331, 385
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 506, 328, 540, 337
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 350, 65, 382, 74
       Destination: 89
    Page: 
     Label: 277
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 56, 124, 127, 133
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 245, 77, 280, 86
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 327, 148, 360, 157
       Destination: 89
    Page: 
     Label: 278
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 126, 65, 298, 74
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 59, 53, 105, 62
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 445, 89, 479, 98
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 484, 53, 518, 62
       Destination: 89
    Page: 
     Label: 279
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 256, 651, 292, 660
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 639, 102, 648
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 181, 603, 292, 612
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 591, 98, 600
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 277, 555, 292, 564
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 53, 544, 73, 552
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 79, 352, 112, 361
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 187, 316, 266, 325
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 119, 233, 213, 242
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 521, 639, 543, 648
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 304, 627, 356, 636
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 461, 615, 494, 624
       Destination: 89
      Annotation: 
       Subtype: Link
       Rect: 338, 496, 451, 505
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 489, 388, 543, 397
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 376, 543, 385
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 364, 386, 373
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 360, 257, 392, 266
       Destination: 134
      Annotation: 
       Subtype: Link
       Rect: 333, 173, 543, 182
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 304, 161, 396, 170
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 383, 65, 543, 74
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 304, 53, 543, 62
       Destination: null
    Page: 
     Label: 280
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 59, 292, 80, 301
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 271, 244, 298, 253
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 59, 232, 107, 241
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 227, 148, 298, 157
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 59, 136, 162, 145
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 125, 77, 158, 86
       Destination: 134
      Annotation: 
       Subtype: Link
       Rect: 367, 244, 549, 253
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 310, 232, 359, 241
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 313, 184, 385, 193
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 533, 64, 549, 72
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 310, 53, 394, 61
       Destination: null
    Page: 
     Label: 281
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 110, 540, 184, 548
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 172, 471, 272, 479
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 278, 471, 292, 479
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 460, 77, 468
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 268, 449, 292, 457
      Annotation: 
       Subtype: Link
       Rect: 53, 438, 118, 446
      Annotation: 
       Subtype: Link
       Rect: 182, 242, 244, 250
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 153, 64, 225, 72
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 246, 64, 292, 72
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 53, 53, 97, 61
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 526, 561, 543, 569
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 304, 550, 364, 558
       Destination: 183
      Annotation: 
       Subtype: Link
       Rect: 359, 397, 468, 405
      Annotation: 
       Subtype: Link
       Rect: 313, 125, 486, 133
    Page: 
     Label: 282
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 59, 403, 298, 411
      Annotation: 
       Subtype: Link
       Rect: 59, 392, 298, 400
      Annotation: 
       Subtype: Link
       Rect: 59, 381, 91, 389
      Annotation: 
       Subtype: Link
       Rect: 59, 367, 298, 375
      Annotation: 
       Subtype: Link
       Rect: 59, 356, 298, 364
      Annotation: 
       Subtype: Link
       Rect: 59, 346, 132, 354
      Annotation: 
       Subtype: Link
       Rect: 59, 332, 298, 340
      Annotation: 
       Subtype: Link
       Rect: 59, 321, 298, 329
      Annotation: 
       Subtype: Link
       Rect: 59, 310, 109, 318
      Annotation: 
       Subtype: Link
       Rect: 59, 296, 298, 304
      Annotation: 
       Subtype: Link
       Rect: 59, 285, 298, 293
      Annotation: 
       Subtype: Link
       Rect: 59, 274, 298, 282
      Annotation: 
       Subtype: Link
       Rect: 59, 264, 163, 272
      Annotation: 
       Subtype: Link
       Rect: 59, 250, 298, 258
      Annotation: 
       Subtype: Link
       Rect: 59, 239, 298, 247
      Annotation: 
       Subtype: Link
       Rect: 59, 228, 173, 236
      Annotation: 
       Subtype: Link
       Rect: 59, 214, 298, 222
      Annotation: 
       Subtype: Link
       Rect: 59, 203, 298, 211
      Annotation: 
       Subtype: Link
       Rect: 59, 192, 86, 200
      Annotation: 
       Subtype: Link
       Rect: 59, 179, 298, 187
      Annotation: 
       Subtype: Link
       Rect: 59, 168, 298, 176
      Annotation: 
       Subtype: Link
       Rect: 59, 157, 286, 165
      Annotation: 
       Subtype: Link
       Rect: 59, 143, 298, 151
      Annotation: 
       Subtype: Link
       Rect: 59, 132, 298, 140
      Annotation: 
       Subtype: Link
       Rect: 59, 121, 298, 129
      Annotation: 
       Subtype: Link
       Rect: 59, 110, 193, 118
      Annotation: 
       Subtype: Link
       Rect: 59, 97, 298, 105
      Annotation: 
       Subtype: Link
       Rect: 59, 86, 298, 94
      Annotation: 
       Subtype: Link
       Rect: 59, 75, 298, 83
      Annotation: 
       Subtype: Link
       Rect: 59, 64, 298, 72
      Annotation: 
       Subtype: Link
       Rect: 59, 53, 131, 61
      Annotation: 
       Subtype: Link
       Rect: 310, 676, 549, 684
      Annotation: 
       Subtype: Link
       Rect: 310, 665, 549, 673
      Annotation: 
       Subtype: Link
       Rect: 310, 654, 428, 662
      Annotation: 
       Subtype: Link
       Rect: 310, 640, 549, 648
      Annotation: 
       Subtype: Link
       Rect: 310, 629, 549, 637
      Annotation: 
       Subtype: Link
       Rect: 310, 618, 549, 626
      Annotation: 
       Subtype: Link
       Rect: 310, 607, 549, 615
      Annotation: 
       Subtype: Link
       Rect: 310, 596, 351, 604
      Annotation: 
       Subtype: Link
       Rect: 310, 581, 549, 589
      Annotation: 
       Subtype: Link
       Rect: 310, 570, 500, 578
      Annotation: 
       Subtype: Link
       Rect: 310, 556, 549, 564
      Annotation: 
       Subtype: Link
       Rect: 310, 545, 549, 553
      Annotation: 
       Subtype: Link
       Rect: 310, 534, 549, 542
      Annotation: 
       Subtype: Link
       Rect: 310, 523, 549, 531
      Annotation: 
       Subtype: Link
       Rect: 310, 512, 475, 520
      Annotation: 
       Subtype: Link
       Rect: 310, 497, 549, 505
      Annotation: 
       Subtype: Link
       Rect: 310, 486, 500, 494
      Annotation: 
       Subtype: Link
       Rect: 310, 472, 549, 480
      Annotation: 
       Subtype: Link
       Rect: 310, 461, 549, 469
      Annotation: 
       Subtype: Link
       Rect: 310, 450, 549, 458
      Annotation: 
       Subtype: Link
       Rect: 310, 439, 411, 447
      Annotation: 
       Subtype: Link
       Rect: 310, 425, 549, 433
      Annotation: 
       Subtype: Link
       Rect: 310, 414, 539, 422
      Annotation: 
       Subtype: Link
       Rect: 310, 399, 549, 407
      Annotation: 
       Subtype: Link
       Rect: 310, 388, 549, 396
      Annotation: 
       Subtype: Link
       Rect: 310, 377, 549, 385
      Annotation: 
       Subtype: Link
       Rect: 310, 366, 549, 374
      Annotation: 
       Subtype: Link
       Rect: 310, 355, 379, 363
      Annotation: 
       Subtype: Link
       Rect: 310, 341, 549, 349
      Annotation: 
       Subtype: Link
       Rect: 310, 330, 547, 338
      Annotation: 
       Subtype: Link
       Rect: 310, 315, 549, 323
      Annotation: 
       Subtype: Link
       Rect: 310, 304, 549, 312
      Annotation: 
       Subtype: Link
       Rect: 310, 293, 346, 301
      Annotation: 
       Subtype: Link
       Rect: 310, 279, 549, 287
      Annotation: 
       Subtype: Link
       Rect: 310, 268, 549, 276
      Annotation: 
       Subtype: Link
       Rect: 310, 257, 549, 265
      Annotation: 
       Subtype: Link
       Rect: 310, 246, 487, 254
      Annotation: 
       Subtype: Link
       Rect: 310, 232, 549, 239
      Annotation: 
       Subtype: Link
       Rect: 310, 221, 549, 229
      Annotation: 
       Subtype: Link
       Rect: 310, 210, 549, 218
      Annotation: 
       Subtype: Link
       Rect: 310, 199, 549, 207
      Annotation: 
       Subtype: Link
       Rect: 310, 188, 447, 196
      Annotation: 
       Subtype: Link
       Rect: 310, 173, 549, 181
      Annotation: 
       Subtype: Link
       Rect: 310, 162, 511, 170
      Annotation: 
       Subtype: Link
       Rect: 310, 148, 549, 156
      Annotation: 
       Subtype: Link
       Rect: 310, 137, 412, 145
      Annotation: 
       Subtype: Link
       Rect: 310, 122, 549, 130
      Annotation: 
       Subtype: Link
       Rect: 310, 111, 549, 119
      Annotation: 
       Subtype: Link
       Rect: 310, 100, 549, 108
      Annotation: 
       Subtype: Link
       Rect: 310, 89, 507, 97
      Annotation: 
       Subtype: Link
       Rect: 310, 75, 549, 83
      Annotation: 
       Subtype: Link
       Rect: 310, 64, 549, 72
      Annotation: 
       Subtype: Link
       Rect: 310, 53, 516, 61
    Page: 
     Label: 283
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 53, 676, 292, 684
      Annotation: 
       Subtype: Link
       Rect: 53, 665, 292, 673
      Annotation: 
       Subtype: Link
       Rect: 53, 654, 292, 662
      Annotation: 
       Subtype: Link
       Rect: 53, 643, 292, 651
      Annotation: 
       Subtype: Link
       Rect: 53, 632, 75, 640
      Annotation: 
       Subtype: Link
       Rect: 53, 618, 292, 626
      Annotation: 
       Subtype: Link
       Rect: 53, 607, 190, 615
      Annotation: 
       Subtype: Link
       Rect: 53, 593, 292, 601
      Annotation: 
       Subtype: Link
       Rect: 53, 582, 292, 590
      Annotation: 
       Subtype: Link
       Rect: 53, 571, 292, 579
      Annotation: 
       Subtype: Link
       Rect: 53, 560, 187, 568
      Annotation: 
       Subtype: Link
       Rect: 53, 546, 292, 554
      Annotation: 
       Subtype: Link
       Rect: 53, 535, 292, 543
      Annotation: 
       Subtype: Link
       Rect: 53, 524, 242, 532
      Annotation: 
       Subtype: Link
       Rect: 53, 509, 292, 517
      Annotation: 
       Subtype: Link
       Rect: 53, 498, 292, 506
      Annotation: 
       Subtype: Link
       Rect: 53, 487, 292, 495
      Annotation: 
       Subtype: Link
       Rect: 53, 477, 93, 485
      Annotation: 
       Subtype: Link
       Rect: 53, 462, 292, 470
      Annotation: 
       Subtype: Link
       Rect: 53, 451, 292, 459
      Annotation: 
       Subtype: Link
       Rect: 53, 440, 292, 448
      Annotation: 
       Subtype: Link
       Rect: 53, 429, 234, 437
      Annotation: 
       Subtype: Link
       Rect: 53, 415, 292, 423
      Annotation: 
       Subtype: Link
       Rect: 53, 404, 292, 412
      Annotation: 
       Subtype: Link
       Rect: 53, 393, 292, 401
      Annotation: 
       Subtype: Link
       Rect: 53, 382, 292, 390
      Annotation: 
       Subtype: Link
       Rect: 53, 371, 71, 379
      Annotation: 
       Subtype: Link
       Rect: 53, 357, 292, 365
      Annotation: 
       Subtype: Link
       Rect: 53, 346, 292, 354
      Annotation: 
       Subtype: Link
       Rect: 53, 335, 292, 343
      Annotation: 
       Subtype: Link
       Rect: 53, 324, 292, 332
      Annotation: 
       Subtype: Link
       Rect: 53, 313, 218, 321
      Annotation: 
       Subtype: Link
       Rect: 53, 299, 292, 307
      Annotation: 
       Subtype: Link
       Rect: 53, 288, 292, 296
      Annotation: 
       Subtype: Link
       Rect: 53, 277, 292, 285
      Annotation: 
       Subtype: Link
       Rect: 53, 266, 292, 274
      Annotation: 
       Subtype: Link
       Rect: 53, 255, 102, 263
      Annotation: 
       Subtype: Link
       Rect: 53, 241, 292, 249
      Annotation: 
       Subtype: Link
       Rect: 53, 230, 292, 238
      Annotation: 
       Subtype: Link
       Rect: 53, 219, 292, 227
      Annotation: 
       Subtype: Link
       Rect: 53, 208, 188, 216
      Annotation: 
       Subtype: Link
       Rect: 53, 194, 292, 202
      Annotation: 
       Subtype: Link
       Rect: 53, 183, 211, 191
      Annotation: 
       Subtype: Link
       Rect: 304, 676, 543, 684
      Annotation: 
       Subtype: Link
       Rect: 304, 665, 543, 673
      Annotation: 
       Subtype: Link
       Rect: 304, 654, 543, 662
      Annotation: 
       Subtype: Link
       Rect: 304, 643, 543, 651
      Annotation: 
       Subtype: Link
       Rect: 304, 632, 543, 640
      Annotation: 
       Subtype: Link
       Rect: 304, 621, 449, 629
      Annotation: 
       Subtype: Link
       Rect: 304, 607, 543, 615
      Annotation: 
       Subtype: Link
       Rect: 304, 596, 543, 604
      Annotation: 
       Subtype: Link
       Rect: 304, 585, 543, 593
      Annotation: 
       Subtype: Link
       Rect: 304, 574, 528, 582
      Annotation: 
       Subtype: Link
       Rect: 304, 560, 543, 568
      Annotation: 
       Subtype: Link
       Rect: 304, 549, 543, 557
      Annotation: 
       Subtype: Link
       Rect: 304, 538, 543, 546
      Annotation: 
       Subtype: Link
       Rect: 304, 528, 371, 535
      Annotation: 
       Subtype: Link
       Rect: 304, 514, 543, 522
      Annotation: 
       Subtype: Link
       Rect: 304, 503, 543, 511
      Annotation: 
       Subtype: Link
       Rect: 304, 492, 503, 500
      Annotation: 
       Subtype: Link
       Rect: 304, 478, 543, 486
      Annotation: 
       Subtype: Link
       Rect: 304, 467, 473, 475
      Annotation: 
       Subtype: Link
       Rect: 304, 453, 543, 461
      Annotation: 
       Subtype: Link
       Rect: 304, 442, 465, 450
      Annotation: 
       Subtype: Link
       Rect: 304, 428, 543, 436
      Annotation: 
       Subtype: Link
       Rect: 304, 417, 543, 425
      Annotation: 
       Subtype: Link
       Rect: 304, 406, 543, 414
      Annotation: 
       Subtype: Link
       Rect: 304, 395, 516, 403
      Annotation: 
       Subtype: Link
       Rect: 304, 381, 543, 389
      Annotation: 
       Subtype: Link
       Rect: 304, 370, 543, 378
      Annotation: 
       Subtype: Link
       Rect: 304, 359, 322, 367
      Annotation: 
       Subtype: Link
       Rect: 304, 345, 543, 353
      Annotation: 
       Subtype: Link
       Rect: 304, 334, 543, 342
      Annotation: 
       Subtype: Link
       Rect: 304, 323, 543, 331
      Annotation: 
       Subtype: Link
       Rect: 304, 312, 543, 320
      Annotation: 
       Subtype: Link
       Rect: 304, 301, 401, 309
      Annotation: 
       Subtype: Link
       Rect: 304, 287, 543, 295
      Annotation: 
       Subtype: Link
       Rect: 304, 276, 543, 284
      Annotation: 
       Subtype: Link
       Rect: 304, 266, 543, 273
      Annotation: 
       Subtype: Link
       Rect: 304, 255, 437, 262
      Annotation: 
       Subtype: Link
       Rect: 304, 241, 543, 249
      Annotation: 
       Subtype: Link
       Rect: 304, 230, 543, 238
      Annotation: 
       Subtype: Link
       Rect: 304, 219, 322, 227
      Annotation: 
       Subtype: Link
       Rect: 304, 205, 543, 213
      Annotation: 
       Subtype: Link
       Rect: 304, 194, 543, 202
      Annotation: 
       Subtype: Link
       Rect: 304, 183, 353, 191
  Checksum: d43a9752
   Type: CRC32
  Checksum: 725e02e33261c8f77b2c72bf094254cd
   Type: MD5
  Checksum: 4e0944a0f6a32f862a729eabf5b7f746ce502dfa
   Type: SHA-1