c9dfa85f49d2ef4ce56e3d47607e8932  pmc_27076187.pdf
f68a04ef5c0309dc9b7019e1cf7018b99cfdd8ec  pmc_27076187.pdf
785997a67abbca7a2f2d8f8c27be71ce2d62273d7257ce1f3ee73c620a807b84  pmc_27076187.pdf

Title:          Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study
Subject:        Annals of Intensive Care, doi:10.1186/s13613-016-0134-8
Keywords:       Biomarkers; C-reactive protein; Procalcitonin; Mid-region fragment of pro-adrenomedullin; Ventilator-associated pneumonia; Clinical Pulmonary Infection Score; Diagnosis; Prediction
Author:         Pedro Póvoa
Creator:        Springer
Producer:       Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
CreationDate:   Mon Apr 11 13:26:45 2016 CEST
ModDate:        Thu Apr 14 02:13:46 2016 CEST
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          11
Encrypted:      no
Page size:      595.276 x 793.701 pts
Page rot:       0
File size:      1488432 bytes
Optimized:      no
PDF version:    1.6

name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
GnkbnsMyriadPro-Light                Type 1C           Custom           yes no  yes     47  0
NnvycfMyriadPro-It                   Type 1C           Custom           yes no  yes     10  0
NjkjpyMyriadPro-Semibold             Type 1C           Custom           yes no  yes     11  0
VnlkpsMyriadPro-Bold                 Type 1C           Custom           yes no  yes      9  0
PslxywMyriadPro-LightIt              Type 1C           Custom           yes no  yes     65  0
BRUBLV+CscmwnMTSY                    Type 1C           Custom           yes yes yes     46  0
FsjvjnMyriadPro-Regular              Type 1C           Custom           yes no  yes     14  0
MfqlskWarnockPro-Regular             Type 1C           Custom           yes no  yes     12  0
AHDAUB+BbcrgbWarnockPro-It           Type 1C           Custom           yes yes yes     13  0
HVMKYV+WnkyvvMyriadPro-SemiboldIt    Type 1C           WinAnsi          yes yes yes     63  0
GGNLTB+HhmtcbSPSMTSYBBold            Type 1C           Custom           yes yes yes     64  0
GrmrnsWarnockPro-LightIt             Type 1C           WinAnsi          yes no  yes    152  0

Jhove (Rel. 1.6, 2011-01-04)
 Date: 2019-02-14 18:49:01 CET
 RepresentationInformation: pmc_27076187.pdf
  ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22)
  LastModified: 2018-02-06 09:04:22 CET
  Size: 1488432
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 1109
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: EN
    Outlines: 
     Item: 
      Title: Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study
      Children: 
       Item: 
        Title: Abstract 
        Children: 
         Item: 
          Title: Background: 
         Item: 
          Title: Methods: 
         Item: 
          Title: Results: 
         Item: 
          Title: Conclusions: 
       Item: 
        Title: Background
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Study design
         Item: 
          Title: Study subjects
         Item: 
          Title: Data collection and management
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Kinetics of biomarkers and inflammatory variables
       Item: 
        Title: Discussion
       Item: 
        Title: Conclusions
       Item: 
        Title: Authors’ contributions
       Item: 
        Title: References
   Info: 
    Title: Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study
    Author: Pedro Póvoa
    Subject: Annals of Intensive Care, doi:10.1186/s13613-016-0134-8
    Keywords: Biomarkers; C-reactive protein; Procalcitonin; Mid-region fragment of pro-adrenomedullin; Ventilator-associated pneumonia; Clinical Pulmonary Infection Score; Diagnosis; Prediction
    Creator: Springer
    Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
    CreationDate: Mon Apr 11 13:56:45 CEST 2016
    ModDate: Thu Apr 14 02:13:46 CEST 2016
   ID: 0xf6fb3214e3cbd10cbc057fcbe0a121fe, 0xc82396371eb543634b3ecf0dec8567e0
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 2
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 46
      ImageHeight: 6
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 96
      ImageHeight: 90
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 46
      ImageHeight: 15
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 46
      ImageHeight: 7
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 46
      ImageHeight: 66
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 46
      ImageHeight: 12
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 46
      ImageHeight: 8
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 46
      ImageHeight: 13
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 22
      ImageHeight: 8
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 4
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 4
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 4
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 3
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 4
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 5
      ImageHeight: 3
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 1595
      ImageHeight: 1421
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1654
      ImageHeight: 2332
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      CompressionScheme: JPEG
      ImageWidth: 1593
      ImageHeight: 2399
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      ImageWidth: 1100
      ImageHeight: 90
      ColorSpace: black is zero
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: GGNLTB+HhmtcbSPSMTSYBBold
      FontSubset: true
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: GGNLTB+HhmtcbSPSMTSYBBold
       Flags: Symbolic
       FontBBox: -16, -935, 987, 896
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PslxywMyriadPro-LightIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: PslxywMyriadPro-LightIt
       Flags: Nonsymbolic, Italic
       FontBBox: -121, -250, 1007, 863
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: GrmrnsWarnockPro-LightIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: GrmrnsWarnockPro-LightIt
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -223, -515, 1437, 929
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: VnlkpsMyriadPro-Bold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: VnlkpsMyriadPro-Bold
       Flags: Nonsymbolic
       FontBBox: -163, -250, 1256, 989
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NnvycfMyriadPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: NnvycfMyriadPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -185, -250, 1090, 953
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NjkjpyMyriadPro-Semibold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: NjkjpyMyriadPro-Semibold
       Flags: Nonsymbolic
       FontBBox: -161, -250, 1198, 972
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MfqlskWarnockPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MfqlskWarnockPro-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -177, -533, 1474, 950
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: AHDAUB+BbcrgbWarnockPro-It
      FontSubset: true
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: AHDAUB+BbcrgbWarnockPro-It
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -221, -533, 1474, 950
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BRUBLV+CscmwnMTSY
      FontSubset: true
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: BRUBLV+CscmwnMTSY
       Flags: Symbolic
       FontBBox: 0, -954, 1043, 796
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FsjvjnMyriadPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: FsjvjnMyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: GnkbnsMyriadPro-Light
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: GnkbnsMyriadPro-Light
       Flags: Nonsymbolic
       FontBBox: -49, -250, 1046, 883
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HVMKYV+WnkyvvMyriadPro-SemiboldIt
      FontSubset: true
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HVMKYV+WnkyvvMyriadPro-SemiboldIt
       Flags: Nonsymbolic, Italic
       FontBBox: -193, -250, 1164, 972
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
   XMP: <x:xmpmeta x:xmptk="Adobe XMP Core 5.2-c001 63.143651, 2012/04/05-09:01:49        " xmlns:x="adobe:ns:meta/">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreateDate>2016-04-11T16:56:45+05:30</xmp:CreateDate>
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2016-04-14T02:13:46+02:00</xmp:ModifyDate>
         <xmp:MetadataDate>2016-04-14T02:13:46+02:00</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)</pdf:Producer>
         <pdf:Keywords>Biomarkers; C-reactive protein; Procalcitonin; Mid-region fragment of pro-adrenomedullin; Ventilator-associated pneumonia; Clinical Pulmonary Infection Score; Diagnosis; Prediction</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1186/s13613-016-0134-8</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer Paris</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Annals of Intensive Care, doi:10.1186/s13613-016-0134-8</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Biomarkers; C-reactive protein; Procalcitonin; Mid-region fragment of pro-adrenomedullin; Ventilator-associated pneumonia; Clinical Pulmonary Infection Score; Diagnosis; Prediction</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Pedro Póvoa</rdf:li>
               <rdf:li>Ignacio Martin-Loeches</rdf:li>
               <rdf:li>Paula Ramirez</rdf:li>
               <rdf:li>Lieuwe D. Bos</rdf:li>
               <rdf:li>Mariano Esperatti</rdf:li>
               <rdf:li>Joana Silvestre</rdf:li>
               <rdf:li>Gisela Gili</rdf:li>
               <rdf:li>Gema Goma</rdf:li>
               <rdf:li>Eugenio Berlanga</rdf:li>
               <rdf:li>Mateu Espasa</rdf:li>
               <rdf:li>Elsa Gonçalves</rdf:li>
               <rdf:li>Antoni Torres</rdf:li>
               <rdf:li>Antonio Artigas</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:DOI>10.1186/s13613-016-0134-8</crossmark:DOI>
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/">
         <prism:url>"http://dx.doi.org/10.1186/s13613-016-0134-8</prism:url>
         <prism:doi>10.1186/s13613-016-0134-8</prism:doi>
         <prism:issn>2110-5820</prism:issn>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Annals of Intensive Care</prism:publicationName>
         <prism:copyright>Póvoa et al.</prism:copyright>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:doi>10.1186/s13613-016-0134-8</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#" xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:1f7a775a-b4bb-42eb-96c4-7d4ebeb888ff</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:f01d1d07-6ff1-420f-a717-38d65b0c0bd6</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:faed590c-3d72-4f9e-9d69-17b404c584e5</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2016-04-11T16:54:29+05:30</stEvt:when>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:751f3333-7315-45f2-98d9-c7a51349d6d9</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2016-04-11T16:55:07+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/" xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#" xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/X ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:MajorVersionDate</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkMajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>robots</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://crossref.org/crossmark/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>crossmark</pdfaSchema:prefix>
                  <pdfaSchema:schema>Crossmark Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The date when a publication was publishe.</pdfaProperty:description>
                           <pdfaProperty:name>MajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://prismstandard.org/namespaces/basic/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). </pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Volume number</pdfaProperty:description>
                           <pdfaProperty:name>volume</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Issue number</pdfaProperty:description>
                           <pdfaProperty:name>number</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Starting page</pdfaProperty:description>
                           <pdfaProperty:name>startingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Ending page</pdfaProperty:description>
                           <pdfaProperty:name>endingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. </pdfaProperty:description>
                           <pdfaProperty:name>aggregationType</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”</pdfaProperty:description>
                           <pdfaProperty:name>publicationName</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Copyright</pdfaProperty:description>
                           <pdfaProperty:name>copyright</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>DocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 182, 81, 307, 73
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 210, 200, 215, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 349, 236, 354, 224
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 439, 200, 444, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 505, 188, 510, 176
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 387, 152, 392, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 377, 116, 382, 104
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 388, 116, 393, 104
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 484, 686, 541, 661
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 102, 645, 107, 633
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 114, 645, 124, 633
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 105, 597, 115, 585
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 121, 597, 131, 585
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 138, 213, 143, 201
       Flags: Print
       AppearanceDictionary: true
       Destination: 43
      Annotation: 
       Subtype: Link
       Rect: 209, 213, 213, 201
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 71, 129, 76, 117
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 259, 105, 269, 93
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 519, 657, 529, 645
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 365, 585, 370, 573
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 365, 513, 375, 501
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 381, 513, 390, 501
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 490, 297, 495, 285
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 180, 245, 190, 233
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 137, 233, 142, 221
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 232, 221, 237, 209
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 458, 257, 463, 245
       Flags: Print
       AppearanceDictionary: true
       Destination: 43
      Annotation: 
       Subtype: Link
       Rect: 342, 161, 346, 149
       Flags: Print
       AppearanceDictionary: true
       Destination: 60
     Thumb: true
    Page: 
     Sequence: 4
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 120, 568, 125, 556
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 86, 496, 91, 484
       Flags: Print
       AppearanceDictionary: true
       Destination: 93
      Annotation: 
       Subtype: Link
       Rect: 72, 232, 77, 220
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 179, 196, 184, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 256, 136, 261, 124
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 322, 508, 327, 496
       Flags: Print
       AppearanceDictionary: true
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 448, 448, 453, 436
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 440, 364, 445, 352
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 322, 244, 327, 232
       Flags: Print
       AppearanceDictionary: true
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 441, 172, 446, 160
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 380, 88, 385, 76
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
     Thumb: true
    Page: 
     Sequence: 6
     Thumb: true
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 93, 247, 98, 235
       Flags: Print
       AppearanceDictionary: true
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 515, 175, 525, 163
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 356, 139, 365, 127
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 329, 103, 339, 91
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
     Thumb: true
    Page: 
     Sequence: 8
     Thumb: true
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 259, 693, 269, 681
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 275, 693, 285, 681
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 191, 669, 201, 657
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 233, 453, 243, 441
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 206, 369, 216, 357
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 220, 369, 230, 357
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 236, 369, 245, 357
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 183, 285, 188, 273
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 193, 285, 202, 273
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 215, 273, 225, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 229, 273, 239, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 257, 249, 267, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 237, 141, 247, 129
       Flags: Print
       AppearanceDictionary: true
       Destination: 161
      Annotation: 
       Subtype: Link
       Rect: 310, 113, 365, 103
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 310, 100, 400, 90
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 201, 308, 230, 300
       Flags: Print
       AppearanceDictionary: true
       Destination: 149
     Thumb: true
    Page: 
     Sequence: 11
     Thumb: true
  Checksum: 87d1f19f
   Type: CRC32
  Checksum: c9dfa85f49d2ef4ce56e3d47607e8932
   Type: MD5
  Checksum: f68a04ef5c0309dc9b7019e1cf7018b99cfdd8ec
   Type: SHA-1