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false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: A role for the spindle assembly checkpoint in the DNA damage response Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Chromosome segregation in response to genotoxic stress is still blocked when Mec1ATR and Tel1ATM signaling is abrogated Item: Title: The SAC blocks chromosome segregation in response to genotoxic stress in a Mec1ATR and Tel1ATM independent manner Item: Title: SAC as part of the DDR Item: Title: Acknowledgments Item: Title: References Info: Title: A role for the spindle assembly checkpoint in the DNA damage response Author: Roger Palou Subject: Current Genetics, doi:10.1007/s00294-016-0634-y Keywords: DNA damage response (DDR),Spindle assembly checkpoint (SAC),S Phase checkpoint,Chromosome segregation,Genomic instability,Cyclin Dependent Kinase (Cdk1) Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows) CreationDate: Wed Aug 03 09:29:48 CEST 2016 ModDate: Fri Mar 31 07:17:17 CEST 2017 ID: 0x89974ff7954ad14188ebdb362ea94503, 0x064bd4c27281b74c8970bb1158c911dd Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 4 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 5 ImageHeight: 4 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 4 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: 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Springer Berlin Heidelberg Current Genetics, doi:10.1007/s00294-016-0634-y DNA damage response (DDR) Spindle assembly checkpoint (SAC) S Phase checkpoint Chromosome segregation Genomic instability Cyclin Dependent Kinase (Cdk1) A role for the spindle assembly checkpoint in the DNA damage response Roger Palou Gloria Palou David G. 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