e1a38cf53ca76ddcdf67af10df6eaceb pmc_27489856.pdf 4c0d5cdc7137143e34047fae2adf763e3ef66e74 pmc_27489856.pdf a1d5cc10e58bb6b3116180ba0e81069489b50f32c4abfad3cc99a24793b7d4ff pmc_27489856.pdf Title: The Verrucomicrobia LexA-Binding Motif: Insights into the Evolutionary Dynamics of the SOS Response Subject: The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. Keywords: SOS response, LexA regulon, DNA repair, comparative genomics, binding motif, translesion synthesis, uracil-DNA glycosylase, regulatory network evolution Author: Jordi Barbé Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Jul 18 07:23:02 2016 CEST ModDate: Mon Jul 18 11:53:27 2016 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 5444708 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LIQTHQ+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 37 0 BPPTAS+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 42 0 PZWYMV+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 52 0 DQMOLM+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 54 0 VSJUGX+HelveticaNeueLTStd-MdIt Type 1C Custom yes yes no 60 0 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UseOutlines Language: en Outlines: Item: Title: The Verrucomicrobia LexA-Binding Motif: Insights into the Evolutionary Dynamics of the SOS Response Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Children: Item: Title: Functional and Taxonomical Assignments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9 Item: Title: Ortholog Detection and Motif Discovery Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8 Item: Title: Analysis Of α3 Helix Motifs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e Item: Title: LexA-Binding Motif Search and Comparative Genomics Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070 Item: Title: Bacterial Strains and Culture Conditions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5 Item: Title: Oligonucleotides and DNA Techniques Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4 Item: Title: Protein Purification and Electrophoresis Mobility Shift Assays Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc Children: Item: Title: LexA Targets a Novel LexA-Binding Motif in the Verrucomicrobia Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1f89ab83 Item: Title: The Verrucomicrobia LexA Protein Targets Tandem Binding Sites in LexA Promoters Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e73f9ac Item: Title: The Core Verrucomicrobia LexA Regulon Comprises Three Operons Involved in DNA Repair and Mutagenesis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@61064425 Item: Title: The Verrucomicrobia LexA Regulon is Highly Variable and Incorporates Novel Functions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b1d7fff Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@299a06ac Children: Item: Title: Variability and Core Elements of the SOS Regulatory Network Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@383534aa Item: Title: A Tandem Model for the Evolution of the LexA-Binding Motif Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6bc168e5 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b3300e5 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2e5c649 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@136432db Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7382f612 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1055e4af Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3caeaf62 Info: Title: The Verrucomicrobia LexA-Binding Motif: Insights into the Evolutionary Dynamics of the SOS Response Author: Jordi Barbé Subject: The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. Keywords: SOS response, LexA regulon, DNA repair, comparative genomics, binding motif, translesion synthesis, uracil-DNA glycosylase, regulatory network evolution Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Jul 18 07:53:02 CEST 2016 ModDate: Mon Jul 18 12:23:27 CEST 2016 ID: 0x327b34559c44ac447b67068d68142278, 0x4f0f84a11d573e48b4dd36282576a915 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 1244 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 1448 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 4016 ImageHeight: 1968 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1890 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bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. SOS response LexA regulon DNA repair comparative genomics binding motif translesion synthesis uracil-DNA glycosylase regulatory network evolution Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 213, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 477, 728, 520, 736 Annotation: Subtype: Link Rect: 520, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 453, 720, 551, 728 Annotation: Subtype: Link Rect: 522, 677, 551, 708 Annotation: Subtype: Link Rect: 43, 31, 147, 38 Annotation: Subtype: Link Rect: 151, 30, 211, 38 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 386, 160, 396 Annotation: Subtype: Link Rect: 98, 238, 160, 247 Annotation: Subtype: Link Rect: 75, 69, 160, 76 Annotation: Subtype: Link Rect: 176, 579, 551, 646 Annotation: Subtype: Link Rect: 176, 557, 213, 565 Annotation: Subtype: Link Rect: 221, 555, 291, 565 Annotation: 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Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 134, 673, 224, 685 Destination: External Annotation: Subtype: Link Rect: 230, 673, 250, 685 Destination: External Annotation: Subtype: Link Rect: 255, 673, 65, 673 Destination: External Annotation: Subtype: Link Rect: 70, 662, 90, 673 Destination: External Annotation: Subtype: Link Rect: 94, 662, 179, 673 Destination: External Annotation: Subtype: Link Rect: 184, 662, 204, 673 Destination: External Annotation: Subtype: Link Rect: 208, 662, 264, 673 Destination: External Annotation: Subtype: Link Rect: 268, 662, 289, 673 Destination: External Annotation: Subtype: Link Rect: 43, 650, 96, 662 Destination: External Annotation: Subtype: Link Rect: 102, 650, 122, 662 Destination: External Annotation: Subtype: Link Rect: 139, 627, 234, 639 Destination: External Annotation: Subtype: Link Rect: 239, 627, 259, 639 Destination: External Annotation: Subtype: Link Rect: 151, 590, 185, 601 Destination: External Annotation: Subtype: Link Rect: 47, 534, 135, 546 Destination: External Annotation: Subtype: Link Rect: 140, 534, 160, 546 Destination: External Annotation: Subtype: Link Rect: 165, 534, 225, 546 Destination: External Annotation: Subtype: Link Rect: 230, 534, 250, 546 Destination: External Annotation: Subtype: Link Rect: 255, 534, 91, 534 Destination: External Annotation: Subtype: Link Rect: 96, 523, 116, 534 Destination: External Annotation: Subtype: Link Rect: 121, 523, 178, 534 Destination: External Annotation: Subtype: Link Rect: 183, 523, 203, 534 Destination: External Annotation: Subtype: Link Rect: 208, 523, 260, 534 Destination: External Annotation: Subtype: Link Rect: 265, 523, 285, 534 Destination: External Annotation: Subtype: Link Rect: 307, 554, 341, 564 Destination: External Annotation: Subtype: Link Rect: 372, 519, 414, 530 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 6 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 211, 235, 246, 245 Destination: External Annotation: Subtype: Link Rect: 201, 133, 235, 143 Destination: External Annotation: Subtype: Link Rect: 162, 87, 202, 97 Destination: External Annotation: Subtype: Link Rect: 418, 373, 459, 383 Destination: External Annotation: Subtype: Link Rect: 514, 179, 549, 189 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 7 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 243, 158, 289, 170 Destination: External Annotation: Subtype: Link Rect: 43, 147, 64, 158 Destination: External Annotation: Subtype: Link Rect: 385, 697, 428, 708 Destination: External Annotation: Subtype: Link Rect: 430, 697, 450, 708 Destination: External Annotation: Subtype: Link Rect: 453, 697, 490, 708 Destination: External Annotation: Subtype: Link Rect: 492, 697, 513, 708 Destination: External Annotation: Subtype: Link Rect: 515, 697, 359, 697 Destination: External Annotation: Subtype: Link Rect: 362, 685, 382, 697 Destination: External Annotation: Subtype: Link Rect: 385, 685, 405, 697 Destination: External Annotation: Subtype: Link Rect: 407, 685, 455, 697 Destination: External Annotation: Subtype: Link Rect: 457, 685, 478, 697 Destination: External Annotation: Subtype: Link Rect: 334, 603, 369, 613 Destination: External Annotation: Subtype: Link Rect: 510, 559, 549, 571 Destination: External Annotation: Subtype: Link Rect: 304, 548, 324, 559 Destination: External Annotation: Subtype: Link Rect: 451, 236, 486, 247 Destination: External Annotation: Subtype: Link Rect: 352, 193, 389, 204 Destination: External Annotation: Subtype: Link Rect: 391, 193, 411, 204 Destination: External Annotation: Subtype: Link Rect: 413, 193, 501, 204 Destination: External Annotation: Subtype: Link Rect: 503, 193, 523, 204 Destination: External Annotation: Subtype: Link Rect: 525, 193, 546, 204 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 8 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 118, 244, 152, 254 Destination: External Annotation: Subtype: Link Rect: 307, 238, 355, 250 Destination: External Annotation: Subtype: Link Rect: 359, 238, 379, 250 Destination: External Annotation: Subtype: Link Rect: 383, 238, 443, 250 Destination: External Annotation: Subtype: Link Rect: 447, 238, 467, 250 Destination: External Annotation: Subtype: Link Rect: 471, 238, 549, 250 Destination: External Annotation: Subtype: Link Rect: 304, 227, 324, 238 Destination: External Annotation: Subtype: Link Rect: 470, 144, 505, 154 Destination: External Annotation: Subtype: Link Rect: 485, 121, 519, 132 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 9 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 47, 477, 88, 489 Destination: External Annotation: Subtype: Link Rect: 93, 477, 113, 489 Destination: External Annotation: Subtype: Link Rect: 118, 477, 177, 489 Destination: External Annotation: Subtype: Link Rect: 182, 477, 202, 489 Destination: External Annotation: Subtype: Link Rect: 207, 477, 260, 489 Destination: External Annotation: Subtype: Link Rect: 265, 477, 285, 489 Destination: External Annotation: Subtype: Link Rect: 272, 454, 68, 454 Destination: External Annotation: Subtype: Link Rect: 75, 443, 95, 454 Destination: External Annotation: Subtype: Link Rect: 47, 397, 181, 408 Destination: External Annotation: Subtype: Link Rect: 186, 397, 207, 408 Destination: External Annotation: Subtype: Link Rect: 212, 397, 263, 408 Destination: External Annotation: Subtype: Link Rect: 268, 397, 289, 408 Destination: External Annotation: Subtype: Link Rect: 43, 386, 82, 397 Destination: External Annotation: Subtype: Link Rect: 87, 386, 107, 397 Destination: External Annotation: Subtype: Link Rect: 112, 386, 164, 397 Destination: External Annotation: Subtype: Link Rect: 169, 386, 189, 397 Destination: External Annotation: Subtype: Link Rect: 194, 386, 289, 397 Destination: External Annotation: Subtype: Link Rect: 43, 374, 64, 386 Destination: External Annotation: Subtype: Link Rect: 71, 282, 114, 294 Destination: External Annotation: Subtype: Link Rect: 116, 282, 136, 294 Destination: External Annotation: Subtype: Link Rect: 138, 282, 176, 294 Destination: External Annotation: Subtype: Link Rect: 178, 282, 198, 294 Destination: External Annotation: Subtype: Link Rect: 200, 282, 289, 294 Destination: External Annotation: Subtype: Link Rect: 43, 271, 64, 282 Destination: External Annotation: Subtype: Link Rect: 67, 271, 87, 282 Destination: External Annotation: Subtype: Link Rect: 90, 271, 139, 282 Destination: External Annotation: Subtype: Link Rect: 142, 271, 162, 282 Destination: External Annotation: Subtype: Link Rect: 247, 168, 289, 179 Destination: External Annotation: Subtype: Link Rect: 43, 156, 64, 168 Destination: External Annotation: Subtype: Link Rect: 68, 156, 126, 168 Destination: External Annotation: Subtype: Link Rect: 130, 156, 150, 168 Destination: External Annotation: Subtype: Link Rect: 155, 156, 207, 168 Destination: External Annotation: Subtype: Link Rect: 211, 156, 231, 168 Destination: External Annotation: Subtype: Link Rect: 232, 97, 267, 107 Destination: External Annotation: Subtype: Link Rect: 383, 443, 447, 454 Destination: External Annotation: Subtype: Link Rect: 450, 443, 470, 454 Destination: External Annotation: Subtype: Link Rect: 524, 408, 549, 420 Destination: External Annotation: Subtype: Link Rect: 304, 397, 324, 408 Destination: External Annotation: Subtype: Link Rect: 330, 397, 372, 408 Destination: External Annotation: Subtype: Link Rect: 377, 397, 398, 408 Destination: External Annotation: Subtype: Link Rect: 509, 363, 392, 363 Destination: External Annotation: Subtype: Link Rect: 398, 351, 418, 363 Destination: External Annotation: Subtype: Link Rect: 424, 351, 464, 363 Destination: External Annotation: Subtype: Link Rect: 470, 351, 490, 363 Destination: External Annotation: Subtype: Link Rect: 496, 351, 549, 363 Destination: External Annotation: Subtype: Link Rect: 304, 340, 324, 351 Destination: External Annotation: Subtype: Link Rect: 368, 269, 402, 279 Destination: External Annotation: Subtype: Link Rect: 510, 237, 328, 237 Destination: External Annotation: Subtype: Link Rect: 336, 225, 356, 237 Destination: External Annotation: Subtype: Link Rect: 465, 191, 522, 202 Destination: External Annotation: Subtype: Link Rect: 525, 191, 546, 202 Destination: External Annotation: Subtype: Link Rect: 444, 166, 482, 176 Destination: External Annotation: Subtype: Link Rect: 484, 168, 491, 176 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 10 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 191, 697, 233, 708 Destination: External Annotation: Subtype: Link Rect: 237, 697, 257, 708 Destination: External Annotation: Subtype: Link Rect: 112, 662, 169, 674 Destination: External Annotation: Subtype: Link Rect: 174, 662, 194, 674 Destination: External Annotation: Subtype: Link Rect: 186, 640, 67, 640 Destination: External Annotation: Subtype: Link Rect: 74, 628, 94, 640 Destination: External Annotation: Subtype: Link Rect: 101, 628, 157, 640 Destination: External Annotation: Subtype: Link Rect: 164, 628, 189, 640 Destination: External Annotation: Subtype: Link Rect: 73, 605, 111, 617 Destination: External Annotation: Subtype: Link Rect: 113, 605, 133, 617 Destination: External Annotation: Subtype: Link Rect: 47, 536, 102, 548 Destination: External Annotation: Subtype: Link Rect: 104, 536, 124, 548 Destination: External Annotation: Subtype: Link Rect: 127, 536, 174, 548 Destination: External Annotation: Subtype: Link Rect: 176, 536, 196, 548 Destination: External Annotation: Subtype: Link Rect: 199, 536, 289, 548 Destination: External Annotation: Subtype: Link Rect: 43, 525, 64, 536 Destination: External Annotation: Subtype: Link Rect: 47, 500, 81, 510 Destination: External Annotation: Subtype: Link Rect: 154, 468, 200, 479 Destination: External Annotation: Subtype: Link Rect: 203, 468, 223, 479 Destination: External Annotation: Subtype: Link Rect: 225, 468, 266, 479 Destination: External Annotation: Subtype: Link Rect: 268, 468, 289, 479 Destination: External Annotation: Subtype: Link Rect: 43, 456, 131, 468 Destination: External Annotation: Subtype: Link Rect: 133, 456, 153, 468 Destination: External Annotation: Subtype: Link Rect: 456, 685, 549, 697 Destination: External Annotation: Subtype: Link Rect: 304, 674, 324, 685 Destination: External Annotation: Subtype: Link Rect: 357, 651, 410, 662 Destination: External Annotation: Subtype: Link Rect: 412, 651, 432, 662 Destination: External Annotation: Subtype: Link Rect: 365, 628, 388, 640 Destination: External Annotation: Subtype: Link Rect: 392, 628, 412, 640 Destination: External Annotation: Subtype: Link Rect: 498, 617, 549, 628 Destination: External Annotation: Subtype: Link Rect: 304, 605, 324, 617 Destination: External Annotation: Subtype: Link Rect: 515, 605, 363, 605 Destination: External Annotation: Subtype: Link Rect: 368, 594, 388, 605 Destination: External Annotation: Subtype: Link Rect: 307, 582, 368, 594 Destination: External Annotation: Subtype: Link Rect: 375, 582, 395, 594 Destination: External Annotation: Subtype: Link Rect: 323, 536, 447, 548 Destination: External Annotation: Subtype: Link Rect: 450, 536, 471, 548 Destination: External Annotation: Subtype: Link Rect: 436, 525, 470, 536 Destination: External Annotation: Subtype: Link Rect: 472, 525, 492, 536 Destination: External Annotation: Subtype: Link Rect: 527, 479, 323, 479 Destination: External Annotation: Subtype: Link Rect: 326, 468, 346, 479 Destination: External Annotation: Subtype: Link Rect: 432, 431, 467, 441 Destination: External Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 11 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 70, 706, 104, 716 Destination: External Annotation: Subtype: Link Rect: 157, 672, 192, 682 Destination: External Annotation: Subtype: Link Rect: 211, 651, 260, 662 Destination: External Annotation: Subtype: Link Rect: 265, 651, 285, 662 Destination: External Annotation: Subtype: Link Rect: 115, 445, 206, 456 Destination: External Annotation: Subtype: Link Rect: 210, 445, 230, 456 Destination: External Annotation: Subtype: Link Rect: 211, 399, 261, 410 Destination: External Annotation: Subtype: Link Rect: 264, 399, 289, 410 Destination: External Annotation: Subtype: Link Rect: 43, 388, 132, 399 Destination: External Annotation: Subtype: Link Rect: 134, 388, 155, 399 Destination: External Annotation: Subtype: Link Rect: 202, 296, 239, 307 Destination: External Annotation: Subtype: Link Rect: 242, 296, 262, 307 Destination: External Annotation: Subtype: Link Rect: 265, 296, 64, 296 Destination: External Annotation: Subtype: Link Rect: 67, 284, 87, 296 Destination: External Annotation: Subtype: Link Rect: 90, 284, 133, 296 Destination: External Annotation: Subtype: Link Rect: 136, 284, 156, 296 Destination: External Annotation: Subtype: Link Rect: 262, 239, 64, 239 Destination: External Annotation: Subtype: Link Rect: 67, 227, 91, 239 Destination: External Annotation: Subtype: Link Rect: 80, 99, 115, 109 Destination: External Annotation: Subtype: Link Rect: 552, 98, 303, 123 Annotation: Subtype: Link Rect: 43, 21, 147, 28 Annotation: Subtype: Link Rect: 151, 19, 211, 28 Annotation: Subtype: Link Rect: 453, 19, 551, 28 Page: Label: 12 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 314, 337, 495, 347 Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 405, 140, 431, 147 Annotation: Subtype: Link Rect: 431, 140, 463, 147 Annotation: Subtype: Link Rect: 463, 140, 499, 147 Annotation: Subtype: Link Rect: 499, 140, 522, 147 Annotation: Subtype: Link Rect: 522, 139, 549, 147 Annotation: Subtype: Link Rect: 43, 30, 147, 37 Annotation: Subtype: Link Rect: 151, 29, 211, 37 Annotation: Subtype: Link Rect: 453, 29, 551, 38 Checksum: aa299631 Type: CRC32 Checksum: e1a38cf53ca76ddcdf67af10df6eaceb Type: MD5 Checksum: 4c0d5cdc7137143e34047fae2adf763e3ef66e74 Type: SHA-1