5fb29bdc2b32e3a8bf7bd76d6d526fd2 pmc_27713878.pdf 0ac2e364293e5be31a347e0525a865560676d57d pmc_27713878.pdf 3a2b0d2ff2a5c360583f4389248235f9ec4f47796067696df5792e8e74be14f0 pmc_27713878.pdf Title: ERK5 and Cell Proliferation: Nuclear Localization Is What Matters Subject: ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. Keywords: MAP kinase, ERK5, nuclear translocation, transcriptional co-activator, cell proliferation, cancer, Hsp90, Cdc37 Author: Jose M. Lizcano Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Sep 19 06:20:17 2016 CEST ModDate: Mon Sep 19 06:28:43 2016 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 603385 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FLCZNJ+HelveticaNeueLTStd-Bd Type 1C WinAnsi yes yes no 24 0 KSHAOL+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 29 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 46 0 PRDVMO+HelveticaNeueLTStd-LtIt Type 1C WinAnsi yes yes no 48 0 RAVQRZ+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 55 0 FVJYYE+MinionPro-Regular Type 1C Custom yes yes no 57 0 XTRGVR+MinionPro-Bold Type 1C Custom yes yes no 132 0 JNJNJU+MinionPro-It Type 1C WinAnsi yes yes no 91 0 OBGWMD+MTSY Type 1C Custom yes yes no 176 0 IAGKPX+MTGU Type 1C Custom yes yes no 315 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2019-02-14 18:36:30 CET RepresentationInformation: pmc_27713878.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2018-02-06 08:48:32 CET Size: 603385 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 370 FreeObjects: 1 IncrementalUpdates: 2 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: ぅげか〵〠ちのつ〠ぃづぬぬ〠ぐひはぬどてづひちぴどはの〺〠ぎふっぬづちひ〠がはっちぬどぺちぴどはの〠ぉび〠しとちぴ〠きちぴぴづひび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Children: Item: Title: ぉのぴひはつふっぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Item: Title: げはぬづ〠はて〠ぅげか〵〠ぐちぴとぷちべ〠どの〠ぎはひねちぬ〠ちのつ〠ぃちのっづひ〠ぃづぬぬ〠ぐひはぬどてづひちぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Item: Title: ぅげか〵〠ぎふっぬづちひ〠こふぢびぴひちぴづび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9 Item: Title: きづっとちのどびねび〠ぉのぶはぬぶづつ〠どの〠ぅげか〵〠ぎふっぬづちひ〠ごひちのびぬはっちぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8 Children: Item: Title: ぎふっぬづちひ〠ごひちのびぬはっちぴどはの〠いづばづのつづのぴ〠はて〠ぅげか〵〠ぃ〭ごづひねどのちぬ〠ぐとはびばとはひべぬちぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e Item: Title: ぎふっぬづちひ〠ごひちのびぬはっちぴどはの〠ぉのつづばづのつづのぴ〠はて〠ぅげか〵〠ぃ〭ごづひねどのちぬ〠ぐとはびばとはひべぬちぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070 Item: Title: ぐづひびばづっぴどぶづび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5 Item: Title: ぁふぴとはひ〠ぃはのぴひどぢふぴどはのび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4 Item: Title: ぁっにのはぷぬづつでねづのぴび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1 Item: Title: げづてづひづのっづび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc Info: Title: ERK5 and Cell Proliferation: Nuclear Localization Is What Matters Author: Jose M. Lizcano Subject: ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. Keywords: MAP kinase, ERK5, nuclear translocation, transcriptional co-activator, cell proliferation, cancer, Hsp90, Cdc37 Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Sep 19 06:50:17 CEST 2016 ModDate: Mon Sep 19 06:58:43 CEST 2016 ID: 0x872ed6f3c29d916edddf8ea90651a1b8, 0x1f3075f20e5e8843a3a7d3c7b37e987f Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 2020 ImageHeight: 1151 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: PRDVMO+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 38 LastChar: 225 FontDescriptor: FontName: PRDVMO+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OBGWMD+MTSY FontSubset: true FirstChar: 67 LastChar: 67 FontDescriptor: FontName: OBGWMD+MTSY Flags: Symbolic, AllCap FontBBox: 0, -83, 724, 583 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: XTRGVR+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: XTRGVR+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 823, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: RAVQRZ+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 122 FontDescriptor: FontName: RAVQRZ+HelveticaNeueLTStd-MdIt Flags: Nonsymbolic, SmallCap FontBBox: -49, -146, 891, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FLCZNJ+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 44 LastChar: 124 FontDescriptor: FontName: FLCZNJ+HelveticaNeueLTStd-Bd Flags: Serif, Nonsymbolic FontBBox: -9, -214, 848, 786 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FVJYYE+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 151 FontDescriptor: FontName: FVJYYE+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: JNJNJU+MinionPro-It FontSubset: true FirstChar: 40 LastChar: 169 FontDescriptor: FontName: JNJNJU+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 712 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IAGKPX+MTGU FontSubset: true FirstChar: 107 LastChar: 107 FontDescriptor: FontName: IAGKPX+MTGU Flags: Symbolic FontBBox: 0, -10, 455, 460 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: KSHAOL+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: KSHAOL+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -30, -214, 773, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PIAOFJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PIAOFJ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding XMP: dvips + MiKTeX GPL Ghostscript 9.0 MAP kinase, ERK5, nuclear translocation, transcriptional co-activator, cell proliferation, cancer, Hsp90, Cdc37 2016-09-19T09:58:43+05:30 2016-09-19T09:50:17+05:30 LaTeX with hyperref package + hypdvips 2016-09-19T09:58:43+05:30 de60a53c-807b-11e6-0000-f4014c4a34f7 uuid:2e3ad108-852b-41a0-9052-4e2147ca6d19 application/pdf ERK5 and Cell Proliferation: Nuclear Localization Is What Matters Jose M. Lizcano ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. MAP kinase ERK5 nuclear translocation transcriptional co-activator cell proliferation cancer Hsp90 Cdc37 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 270, 755 Annotation: Subtype: Link Rect: 504, 736, 551, 744 Annotation: Subtype: Link Rect: 456, 728, 498, 736 Annotation: Subtype: Link Rect: 498, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 458, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 175, 38 Annotation: Subtype: Link Rect: 179, 30, 239, 38 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 402, 160, 412 Annotation: Subtype: Link Rect: 78, 245, 160, 253 Annotation: Subtype: Link Rect: 80, 75, 160, 83 Annotation: Subtype: Link Rect: 176, 620, 551, 660 Annotation: Subtype: Link Rect: 241, 595, 299, 603 Annotation: Subtype: Link Rect: 317, 595, 386, 603 Annotation: Subtype: Link Rect: 323, 87, 360, 98 Destination: External Annotation: Subtype: Link Rect: 364, 87, 384, 98 Destination: External Annotation: Subtype: Link Rect: 387, 87, 432, 98 Destination: External Annotation: Subtype: Link Rect: 435, 87, 455, 98 Destination: External Annotation: Subtype: Link Rect: 459, 87, 549, 98 Destination: External Annotation: Subtype: Link Rect: 176, 75, 197, 87 Destination: External Page: Label: 2 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 74, 708, 122, 720 Destination: External Annotation: Subtype: Link Rect: 128, 708, 148, 720 Destination: External Annotation: Subtype: Link Rect: 197, 662, 289, 674 Destination: External Annotation: Subtype: Link Rect: 43, 651, 64, 662 Destination: External Annotation: Subtype: Link Rect: 205, 640, 253, 651 Destination: External Annotation: Subtype: Link Rect: 257, 640, 277, 651 Destination: External Annotation: Subtype: Link Rect: 244, 617, 289, 628 Destination: External Annotation: Subtype: Link Rect: 43, 605, 64, 617 Destination: External Annotation: Subtype: Link Rect: 77, 594, 142, 605 Destination: External Annotation: Subtype: Link Rect: 147, 594, 167, 605 Destination: External Annotation: Subtype: Link Rect: 171, 594, 217, 605 Destination: External Annotation: Subtype: Link Rect: 221, 594, 241, 605 Destination: External Annotation: Subtype: Link Rect: 120, 559, 166, 571 Destination: External Annotation: Subtype: Link Rect: 168, 559, 189, 571 Destination: External Annotation: Subtype: Link Rect: 130, 502, 175, 514 Destination: External Annotation: Subtype: Link Rect: 177, 502, 197, 514 Destination: External Annotation: Subtype: Link Rect: 160, 410, 206, 422 Destination: External Annotation: Subtype: Link Rect: 212, 410, 232, 422 Destination: External Annotation: Subtype: Link Rect: 47, 376, 92, 388 Destination: External Annotation: Subtype: Link Rect: 98, 376, 118, 388 Destination: External Annotation: Subtype: Link Rect: 166, 353, 210, 365 Destination: External Annotation: Subtype: Link Rect: 214, 353, 234, 365 Destination: External Annotation: Subtype: Link Rect: 176, 342, 221, 353 Destination: External Annotation: Subtype: Link Rect: 224, 342, 244, 353 Destination: External Annotation: Subtype: Link Rect: 126, 330, 184, 342 Destination: External Annotation: Subtype: Link Rect: 188, 330, 209, 342 Destination: External Annotation: Subtype: Link Rect: 128, 319, 176, 330 Destination: External Annotation: Subtype: Link Rect: 179, 319, 199, 330 Destination: External Annotation: Subtype: Link Rect: 211, 284, 252, 296 Destination: External Annotation: Subtype: Link Rect: 255, 284, 276, 296 Destination: External Annotation: Subtype: Link Rect: 103, 261, 188, 273 Destination: External Annotation: Subtype: Link Rect: 193, 261, 213, 273 Destination: External Annotation: Subtype: Link Rect: 264, 227, 101, 227 Destination: External Annotation: Subtype: Link Rect: 103, 216, 123, 227 Destination: External Annotation: Subtype: Link Rect: 208, 170, 261, 181 Destination: External Annotation: Subtype: Link Rect: 265, 170, 285, 181 Destination: External Annotation: Subtype: Link Rect: 268, 135, 63, 135 Destination: External Annotation: Subtype: Link Rect: 65, 124, 85, 135 Destination: External Annotation: Subtype: Link Rect: 87, 124, 128, 135 Destination: External Annotation: Subtype: Link Rect: 130, 124, 150, 135 Destination: External Annotation: Subtype: Link Rect: 128, 90, 173, 101 Destination: External Annotation: Subtype: Link Rect: 176, 90, 196, 101 Destination: External Annotation: Subtype: Link Rect: 448, 708, 490, 720 Destination: External Annotation: Subtype: Link Rect: 492, 708, 512, 720 Destination: External Annotation: Subtype: Link Rect: 307, 674, 387, 685 Destination: External Annotation: Subtype: Link Rect: 391, 674, 411, 685 Destination: External Annotation: Subtype: Link Rect: 415, 674, 460, 685 Destination: External Annotation: Subtype: Link Rect: 463, 674, 484, 685 Destination: External Annotation: Subtype: Link Rect: 487, 674, 549, 685 Destination: External Annotation: Subtype: Link Rect: 304, 662, 324, 674 Destination: External Annotation: Subtype: Link Rect: 326, 662, 439, 674 Destination: External Annotation: Subtype: Link Rect: 441, 662, 462, 674 Destination: External Annotation: Subtype: Link Rect: 382, 605, 450, 617 Destination: External Annotation: Subtype: Link Rect: 453, 605, 473, 617 Destination: External Annotation: Subtype: Link Rect: 477, 605, 522, 617 Destination: External Annotation: Subtype: Link Rect: 525, 605, 546, 617 Destination: External Annotation: Subtype: Link Rect: 452, 559, 482, 568 Destination: External Annotation: Subtype: Link Rect: 349, 456, 418, 468 Destination: External Annotation: Subtype: Link Rect: 421, 456, 442, 468 Destination: External Annotation: Subtype: Link Rect: 445, 456, 492, 468 Destination: External Annotation: Subtype: Link Rect: 495, 456, 515, 468 Destination: External Annotation: Subtype: Link Rect: 519, 456, 325, 456 Destination: External Annotation: Subtype: Link Rect: 330, 445, 350, 456 Destination: External Annotation: Subtype: Link Rect: 354, 445, 409, 456 Destination: External Annotation: Subtype: Link Rect: 414, 445, 434, 456 Destination: External Annotation: Subtype: Link Rect: 337, 388, 386, 399 Destination: External Annotation: Subtype: Link Rect: 389, 388, 409, 399 Destination: External Annotation: Subtype: Link Rect: 509, 365, 323, 365 Destination: External Annotation: Subtype: Link Rect: 325, 353, 345, 365 Destination: External Annotation: Subtype: Link Rect: 307, 181, 382, 193 Destination: External Annotation: Subtype: Link Rect: 385, 181, 406, 193 Destination: External Annotation: Subtype: Link Rect: 370, 147, 423, 158 Destination: External Annotation: Subtype: Link Rect: 430, 147, 450, 158 Destination: External Annotation: Subtype: Link Rect: 323, 67, 386, 78 Destination: External Annotation: Subtype: Link Rect: 389, 67, 409, 78 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Page: Label: 3 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 467, 671, 511, 681 Destination: External Annotation: Subtype: Link Rect: 513, 671, 530, 681 Destination: External Annotation: Subtype: Link Rect: 467, 662, 505, 671 Destination: External Annotation: Subtype: Link Rect: 507, 662, 524, 671 Destination: External Annotation: Subtype: Link Rect: 467, 650, 500, 659 Destination: External Annotation: Subtype: Link Rect: 502, 650, 519, 659 Destination: External Annotation: Subtype: Link Rect: 467, 629, 509, 638 Destination: External Annotation: Subtype: Link Rect: 511, 629, 529, 638 Destination: External Annotation: Subtype: Link Rect: 467, 598, 497, 607 Destination: External Annotation: Subtype: Link Rect: 499, 598, 516, 607 Destination: External Annotation: Subtype: Link Rect: 467, 586, 505, 595 Destination: External Annotation: Subtype: Link Rect: 507, 586, 525, 595 Destination: External Annotation: Subtype: Link Rect: 467, 565, 530, 574 Destination: External Annotation: Subtype: Link Rect: 532, 565, 550, 574 Destination: External Annotation: Subtype: Link Rect: 467, 544, 506, 553 Destination: External Annotation: Subtype: Link Rect: 508, 544, 525, 553 Destination: External Annotation: Subtype: Link Rect: 467, 522, 506, 532 Destination: External Annotation: Subtype: Link Rect: 508, 522, 526, 532 Destination: External Annotation: Subtype: Link Rect: 467, 501, 515, 511 Destination: External Annotation: Subtype: Link Rect: 516, 501, 534, 511 Destination: External Annotation: Subtype: Link Rect: 467, 489, 510, 499 Destination: External Annotation: Subtype: Link Rect: 512, 489, 530, 499 Destination: External Annotation: Subtype: Link Rect: 467, 477, 516, 487 Destination: External Annotation: Subtype: Link Rect: 518, 477, 535, 487 Destination: External Annotation: Subtype: Link Rect: 467, 456, 509, 466 Destination: External Annotation: Subtype: Link Rect: 511, 456, 528, 466 Destination: External Annotation: Subtype: Link Rect: 47, 371, 106, 382 Destination: External Annotation: Subtype: Link Rect: 109, 371, 129, 382 Destination: External Annotation: Subtype: Link Rect: 136, 336, 193, 348 Destination: External Annotation: Subtype: Link Rect: 196, 336, 216, 348 Destination: External Annotation: Subtype: Link Rect: 214, 290, 289, 302 Destination: External Annotation: Subtype: Link Rect: 43, 279, 64, 290 Destination: External Annotation: Subtype: Link Rect: 74, 267, 115, 279 Destination: External Annotation: Subtype: Link Rect: 118, 267, 138, 279 Destination: External Annotation: Subtype: Link Rect: 162, 210, 208, 222 Destination: External Annotation: Subtype: Link Rect: 213, 210, 233, 222 Destination: External Annotation: Subtype: Link Rect: 238, 210, 289, 222 Destination: External Annotation: Subtype: Link Rect: 43, 199, 64, 210 Destination: External Annotation: Subtype: Link Rect: 247, 141, 289, 153 Destination: External Annotation: Subtype: Link Rect: 43, 130, 64, 141 Destination: External Annotation: Subtype: Link Rect: 475, 393, 522, 405 Destination: External Annotation: Subtype: Link Rect: 529, 393, 549, 405 Destination: External Annotation: Subtype: Link Rect: 304, 382, 324, 393 Destination: External Annotation: Subtype: Link Rect: 396, 336, 482, 348 Destination: External Annotation: Subtype: Link Rect: 484, 336, 504, 348 Destination: External Annotation: Subtype: Link Rect: 508, 302, 549, 313 Destination: External Annotation: Subtype: Link Rect: 304, 290, 324, 302 Destination: External Annotation: Subtype: Link Rect: 307, 256, 347, 267 Destination: External Annotation: Subtype: Link Rect: 350, 256, 370, 267 Destination: External Annotation: Subtype: Link Rect: 345, 72, 392, 83 Destination: External Annotation: Subtype: Link Rect: 396, 72, 416, 83 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Page: Label: 4 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 78, 697, 165, 708 Destination: External Annotation: Subtype: Link Rect: 170, 697, 190, 708 Destination: External Annotation: Subtype: Link Rect: 103, 662, 147, 674 Destination: External Annotation: Subtype: Link Rect: 149, 662, 169, 674 Destination: External Annotation: Subtype: Link Rect: 267, 640, 64, 640 Destination: External Annotation: Subtype: Link Rect: 68, 628, 88, 640 Destination: External Annotation: Subtype: Link Rect: 131, 594, 184, 605 Destination: External Annotation: Subtype: Link Rect: 187, 594, 207, 605 Destination: External Annotation: Subtype: Link Rect: 149, 536, 176, 548 Destination: External Annotation: Subtype: Link Rect: 178, 536, 199, 548 Destination: External Annotation: Subtype: Link Rect: 47, 422, 170, 433 Destination: External Annotation: Subtype: Link Rect: 176, 422, 196, 433 Destination: External Annotation: Subtype: Link Rect: 202, 422, 289, 433 Destination: External Annotation: Subtype: Link Rect: 43, 410, 64, 422 Destination: External Annotation: Subtype: Link Rect: 67, 410, 112, 422 Destination: External Annotation: Subtype: Link Rect: 115, 410, 135, 422 Destination: External Annotation: Subtype: Link Rect: 131, 365, 197, 376 Destination: External Annotation: Subtype: Link Rect: 202, 365, 222, 376 Destination: External Annotation: Subtype: Link Rect: 104, 342, 139, 353 Destination: External Annotation: Subtype: Link Rect: 142, 342, 162, 353 Destination: External Annotation: Subtype: Link Rect: 47, 191, 81, 201 Destination: External Annotation: Subtype: Link Rect: 184, 135, 228, 147 Destination: External Annotation: Subtype: Link Rect: 231, 135, 251, 147 Destination: External Annotation: Subtype: Link Rect: 223, 113, 289, 124 Destination: External Annotation: Subtype: Link Rect: 43, 101, 64, 113 Destination: External Annotation: Subtype: Link Rect: 206, 90, 258, 101 Destination: External Annotation: Subtype: Link Rect: 265, 90, 285, 101 Destination: External Annotation: Subtype: Link Rect: 392, 674, 439, 685 Destination: External Annotation: Subtype: Link Rect: 443, 674, 464, 685 Destination: External Annotation: Subtype: Link Rect: 355, 651, 401, 662 Destination: External Annotation: Subtype: Link Rect: 405, 651, 425, 662 Destination: External Annotation: Subtype: Link Rect: 307, 640, 372, 651 Destination: External Annotation: Subtype: Link Rect: 377, 640, 397, 651 Destination: External Annotation: Subtype: Link Rect: 401, 640, 521, 651 Destination: External Annotation: Subtype: Link Rect: 525, 640, 546, 651 Destination: External Annotation: Subtype: Link Rect: 528, 571, 404, 571 Destination: External Annotation: Subtype: Link Rect: 409, 559, 430, 571 Destination: External Annotation: Subtype: Link Rect: 435, 559, 520, 571 Destination: External Annotation: Subtype: Link Rect: 525, 559, 546, 571 Destination: External Annotation: Subtype: Link Rect: 307, 456, 430, 468 Destination: External Annotation: Subtype: Link Rect: 436, 456, 456, 468 Destination: External Annotation: Subtype: Link Rect: 462, 456, 549, 468 Destination: External Annotation: Subtype: Link Rect: 304, 445, 324, 456 Destination: External Annotation: Subtype: Link Rect: 505, 227, 549, 239 Destination: External Annotation: Subtype: Link Rect: 304, 216, 324, 227 Destination: External Annotation: Subtype: Link Rect: 388, 170, 432, 181 Destination: External Annotation: Subtype: Link Rect: 434, 170, 454, 181 Destination: External Annotation: Subtype: Link Rect: 373, 124, 459, 135 Destination: External Annotation: Subtype: Link Rect: 462, 124, 483, 135 Destination: External Annotation: Subtype: Link Rect: 432, 90, 499, 101 Destination: External Annotation: Subtype: Link Rect: 504, 90, 525, 101 Destination: External Annotation: Subtype: Link Rect: 530, 90, 328, 90 Destination: External Annotation: Subtype: Link Rect: 334, 78, 354, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Page: Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 295, 376, 330, 385 Destination: External Annotation: Subtype: Link Rect: 332, 376, 350, 385 Destination: External Annotation: Subtype: Link Rect: 325, 357, 360, 366 Destination: External Annotation: Subtype: Link Rect: 362, 357, 380, 366 Destination: External Annotation: Subtype: Link Rect: 368, 319, 458, 328 Destination: External Annotation: Subtype: Link Rect: 460, 319, 477, 328 Destination: External Annotation: Subtype: Link Rect: 479, 319, 542, 328 Destination: External Annotation: Subtype: Link Rect: 49, 309, 66, 319 Destination: External Annotation: Subtype: Link Rect: 161, 300, 196, 309 Destination: External Annotation: Subtype: Link Rect: 198, 300, 215, 309 Destination: External Annotation: Subtype: Link Rect: 173, 251, 221, 263 Destination: External Annotation: Subtype: Link Rect: 226, 251, 246, 263 Destination: External Annotation: Subtype: Link Rect: 86, 228, 133, 240 Destination: External Annotation: Subtype: Link Rect: 136, 228, 157, 240 Destination: External Annotation: Subtype: Link Rect: 161, 228, 224, 240 Destination: External Annotation: Subtype: Link Rect: 228, 228, 248, 240 Destination: External Annotation: Subtype: Link Rect: 451, 114, 500, 125 Destination: External Annotation: Subtype: Link Rect: 504, 114, 524, 125 Destination: External Annotation: Subtype: Link Rect: 372, 91, 411, 102 Destination: External Annotation: Subtype: Link Rect: 415, 91, 436, 102 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Page: Label: 6 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 339, 676, 370, 684 Destination: External Annotation: Subtype: Link Rect: 418, 674, 453, 684 Destination: External Annotation: Subtype: Link Rect: 43, 28, 175, 37 Annotation: Subtype: Link Rect: 179, 28, 239, 36 Annotation: Subtype: Link Rect: 427, 28, 551, 37 Page: Label: 7 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 405, 140, 431, 147 Annotation: Subtype: Link Rect: 431, 140, 463, 147 Annotation: Subtype: Link Rect: 463, 140, 499, 148 Annotation: Subtype: Link Rect: 499, 140, 522, 147 Annotation: Subtype: Link Rect: 522, 139, 549, 148 Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 427, 29, 551, 38 Checksum: bdf694d6 Type: CRC32 Checksum: 5fb29bdc2b32e3a8bf7bd76d6d526fd2 Type: MD5 Checksum: 0ac2e364293e5be31a347e0525a865560676d57d Type: SHA-1