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Invalid destination object Offset: 187847 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 300 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Exome chip analyses in adult attention deficit hyperactivity disorder Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@16f65612 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@311d617d Item: Title: Materials and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7c53a9eb Children: Item: Title: Subjects Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed17bee Item: Title: Genotyping, genotype calling and quality control Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2a33fae0 Item: Title: Statistical analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@707f7052 Item: Title: Examination of rare coding variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11028347 Item: Title: Examination of common variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@14899482 Item: Title: In silico functional analyses of the significant loci Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Item: Title: Exploration of biological pathways: GO terms Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Item: Title: Gene expression in brain tissue Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9 Children: Item: Title: Subjects and genotyping Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8 Item: Title: Examination of rare coding variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e Item: Title: Table 1 Properties of the IMpACT discovery samples examined in this study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070 Children: Item: Title: Examination of common variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5 Item: Title: In silico functional analyses of the significant loci Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4 Item: Title: Exploration of biological pathways: GO terms Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1 Item: Title: Table 2 Summary of effect severity of the rare coding missense variants in the NT5DC1 gene with observed minor allele frequenc礀 戀攀氀漀眀 琀栀攀 攀猀琀愀戀氀椀猀栀攀搀 挀爀椀琀椀挀愀氀 琀栀爀攀猀栀漀氀搩㸾൥湤潢樍㄰㘠〠潢樍㰼⽐慲敮琠㄰㔠〠刯䑥獴⣾＀䈀㄀㐩⽔楴汥⣾＀䜀攀渀攀 攀砀瀀爀攀猀猀椀漀渀 椀渀 戀爀愀椀渀 琀椀猀猀甀攩㸾൥湤潢樍㄰㜠〠潢樍㰼⽆楲獴‱〸‰⁒⽐慲敮琠㤸‰⁒⽎數琠㄰㔠〠刯䑥獴⣾＀琀愀戀开戀欀琀戀氀琀ㄩ⽃潵湴‭㌯䱡獴‱〹‰⁒⽐牥瘠ㄱ〠〠刯呩瑬攨Table 1 Properties of the IMpACT discovery samples examined in this study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc Children: Item: Title: Gene expression in brain tissue Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1f89ab83 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e73f9ac Item: Title: We are grateful to the participants of the study. Special acknowledgment is due to Benjamin Neale and Christiaan de Leeuw for 椀渀瘀愀氀甀愀戀氀攀 椀渀猀椀最栀琀 愀渀搀 猀甀最最攀猀琀椀漀渀猀 爀攀最愀爀搀椀渀最 琀栀攀 瀀爀攀猀攀渀琀攀搀 搀愀琀愀⸀ 圀攀 琀栀愀渀欀 琀栀攀 唀䬀 䔀砀漀洀攀 䌀栀椀瀀 挀漀渀猀漀爀琀椀甀洀 昀漀爀 愀挀挀攀猀猀 琀漀 挀漀渀琀爀漀氀 琀栀敜ഀ
㸾൥湤潢樍㄰㐠〠潢樍㰼⽐慲敮琠㤸‰⁒⽎數琠㄰㌠〠刯䑥獴⣾＀䄀㐩⽐牥瘠㄰㔠〠刯呩瑬攨Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@61064425 Item: Title: We are grateful to the participants of the study. Special acknowledgment is due to Benjamin Neale and Christiaan de Leeuw for 椀渀瘀愀氀甀愀戀氀攀 椀渀猀椀最栀琀 愀渀搀 猀甀最最攀猀琀椀漀渀猀 爀攀最愀爀搀椀渀最 琀栀攀 瀀爀攀猀攀渀琀攀搀 搀愀琀愀⸀ 圀攀 琀栀愀渀欀 琀栀攀 唀䬀 䔀砀漀洀攀 䌀栀椀瀀 挀漀渀猀漀爀琀椀甀洀 昀漀爀 愀挀挀攀猀猀 琀漀 挀漀渀琀爀漀氀 琀栀敜ഀ
㸾൥湤潢樍㄰㌠〠潢樍㰼⽐慲敮琠㤸‰⁒⽎數琠㄰㈠〠刯䑥獴⣾＀䄀㔩⽐牥瘠㄰㐠〠刯呩瑬攨We are grateful to the participants of the study. Special acknowledgment is due to Benjamin Neale and Christiaan de Leeuw for 椀渀瘀愀氀甀愀戀氀攀 椀渀猀椀最栀琀 愀渀搀 猀甀最最攀猀琀椀漀渀猀 爀攀最愀爀搀椀渀最 琀栀攀 瀀爀攀猀攀渀琀攀搀 搀愀琀愀⸀ 圀攀 琀栀愀渀欀 琀栀攀 唀䬀 䔀砀漀洀攀 䌀栀椀瀀 挀漀渀猀漀爀琀椀甀洀 昀漀爀 愀挀挀攀猀猀 琀漀 挀漀渀琀爀漀氀 琀栀敜ഀ
㸾൥湤潢樍㄰㐠〠潢樍㰼⽐慲敮琠㤸‰⁒⽎數琠㄰㌠〠刯䑥獴⣾＀䄀㐩⽐牥瘠㄰㔠〠刯呩瑬攨Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b1d7fff Item: Title: ACKNOWLEDGEMENTS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@299a06ac Item: Title: REFERENCES Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@383534aa Info: Title: Exome chip analyses in adult attention deficit hyperactivity disorder Author: T Zayats Subject: Translational Psychiatry 6, e923 (2016). doi:10.1038/tp.2016.196 Creator: Producer: CreationDate: Wed Oct 12 17:33:43 CEST 2016 ModDate: Thu Oct 13 13:19:22 CEST 2016 ID: 0x95d7c724917b2a8f461c5345b88b491a, 0x78a027fef85a6943b809cf366c3eb804 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: CJMBLD+AdvOT8608a8d1+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: CJMBLD+AdvOT8608a8d1+03 Flags: Symbolic FontBBox: -479, -364, 854, 927 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: 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FontName: CJMBLE+AdvTT6780a46b+fb Flags: Symbolic FontBBox: 9, 0, 875, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CJMBMF+AdvTT6780a46b+20 FontSubset: true FirstChar: 151 LastChar: 151 FontDescriptor: FontName: CJMBMF+AdvTT6780a46b+20 Flags: Nonsymbolic FontBBox: 0, -114, 1156, 750 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1038/tp.2016.196 T Zayats K K Jacobsen R Kleppe C P Jacob S Kittel-Schneider M Ribasés J A Ramos-Quiroga V Richarte M Casas N R Mota E H Grevet M Klein J Corominas J Bralten T Galesloot A A Vasquez S Herms A J Forstner H Larsson G Breen P Asherson S Gross-Lesch K P Lesch S Cichon M B Gabrielsen O L Holmen C H D Bau J Buitelaar L Kiemeney S V Faraone B Cormand B Franke A Reif J Haavik S Johansson Translational Psychiatry 6, e923 (2016). doi:10.1038/tp.2016.196 Nature Publishing Group © 2016 The Author(s) Exome chip analyses in adult attention deficit hyperactivity disorder © 10.1038/tp.2016.196 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