e6316789b13f18f1503336c54c4376e1 epigenetics_a2017v12n7p515iENG.pdf 1fb95cf7813bef7c904115f4763067893471f17e epigenetics_a2017v12n7p515iENG.pdf 835e235157f61ff3081de19f85e038dea5dce9f870041196c5c4dd56beb73562 epigenetics_a2017v12n7p515iENG.pdf Title: Emerging roles of macrosatellite repeats in genome organization and disease development Subject: Epigenetics, 2017. doi:10.1080/15592294.2017.1318235 Keywords: DNA repeats,epigenetics,genome organization,macrosatellite repeats,noncoding genome Author: Gabrijela Dumbovic Creator: Arbortext Advanced Print Publisher 10.0.1062/W Unicode Producer: Acrobat Distiller 10.1.10 (Windows) CreationDate: Wed Aug 2 04:24:29 2017 CEST ModDate: Wed Aug 2 04:25:05 2017 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 593.972 x 792 pts Page rot: 0 File size: 809295 bytes Optimized: yes PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JJOACP+AdvOT46dcae81 Type 1C WinAnsi yes yes no 601 0 JJOAJO+AdvOTce3d9a73 Type 1C WinAnsi yes yes no 598 0 JJOAKO+AdvOT5fcf1b24 Type 1C WinAnsi yes yes no 595 0 JJOAKP+AdvOT5fcf1b24+20 Type 1C WinAnsi yes yes no 592 0 JJOALA+AdvP4C4E59 Type 1C Custom yes yes yes 587 0 JJOALB+AdvOT2bda31c3.B Type 1C WinAnsi yes yes no 584 0 JJOAMC+AdvOT46dcae81+fb Type 1C Custom yes yes yes 579 0 JJOAMD+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 576 0 JJOAMF+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 573 0 JJOAMG+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 568 0 JJOAME+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 565 0 JJOBGD+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 354 0 JJOBHE+AdvP4C9543 Type 1C WinAnsi yes yes no 351 0 JJOBHF+AdvOTd0125be5.BI Type 1C WinAnsi yes yes no 348 0 JJODCK+AdvOTc20ddc96 Type 1C WinAnsi yes yes no 345 0 JJODCL+AdvOT5fcf1b24+fb Type 1C Custom yes yes yes 7 0 JJODIL+AdvP4C4E74 Type 1C Custom yes yes no 30 0 JJODIK+AdvOT5c7b8c86.I Type 1C WinAnsi yes yes no 357 0 JJPDLC+AdvOTd0125be5.BI+fb Type 1C Custom yes yes yes 360 0 JJPEHO+AdvOT3b30f6db.B+fb Type 1C Custom yes yes yes 139 0 JJPFAL+AdvTT5843c571 Type 1C WinAnsi yes yes no 181 0 JJPGFE+AdvP4C9542 Type 1C WinAnsi yes yes no 235 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2019-02-14 18:17:28 CET RepresentationInformation: epigenetics_a2017v12n7p515iENG.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2018-10-17 15:35:51 CEST Size: 809295 Format: PDF Version: 1.3 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 ErrorMessage: Invalid destination object Offset: 768187 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 646 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: OneColumn PageMode: UseOutlines Language: en Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2a33fae0 Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@707f7052 Children: Item: Title: Coding, noncoding, and architectural roles of macrosatellite repeats in genome organization and disease development Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11028347 Item: Title: D4Z4 macrosatellite regulates local chromatin structure in a copy number dependent manner Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@14899482 Item: Title: DXZ4 macrosatellite regulates higher order nuclear architecture Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Item: Title: NBL2 macrosatellite is hypomethylated in many types of cancer Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Item: Title: RS447 macrosatellite codes for ubiquitin-specific protease 17 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Item: Title: RNU2 macrosatellite encodes for a housekeeping small noncoding RNA Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9 Item: Title: TAF11-Like macrosatellite codes for a TAF family factor Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8 Item: Title: CT47, a macrosatellite with testis-specific expression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e Item: Title: Conclusion and future perspectives Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070 Item: Title: Disclosure of potential conflicts of interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc Info: Title: Emerging roles of macrosatellite repeats in genome organization and disease development Author: Gabrijela Dumbovic Subject: Epigenetics, 2017. doi:10.1080/15592294.2017.1318235 Keywords: DNA repeats,epigenetics,genome organization,macrosatellite repeats,noncoding genome Creator: Arbortext Advanced Print Publisher 10.0.1062/W Unicode Producer: Acrobat Distiller 10.1.10 (Windows) CreationDate: Wed Aug 02 04:54:29 CEST 2017 ModDate: Wed Aug 02 04:55:05 CEST 2017 ID: 0x5d7a7c68b94d4bb5ed092844b5016c7b, 0x18ba1a50c3eee4fd4e9a15d912b9df39 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 732 ImageHeight: 439 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1424 ImageHeight: 594 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1139 ImageHeight: 742 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1424 ImageHeight: 843 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Fonts: Type1: Font: BaseFont: JJOAMD+AdvOT3b30f6db.B FontSubset: true FirstChar: 65 LastChar: 119 FontDescriptor: FontName: JJOAMD+AdvOT3b30f6db.B Flags: Nonsymbolic FontBBox: -31, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOBGD+AdvOT7d6df7ab.I FontSubset: true FirstChar: 45 LastChar: 118 FontDescriptor: FontName: JJOBGD+AdvOT7d6df7ab.I Flags: Nonsymbolic FontBBox: -135, -250, 1000, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAMC+AdvOT46dcae81+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JJOAMC+AdvOT46dcae81+fb Flags: Symbolic FontBBox: 0, 0, 739, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJODIK+AdvOT5c7b8c86.I FontSubset: true FirstChar: 45 LastChar: 116 FontDescriptor: FontName: JJODIK+AdvOT5c7b8c86.I Flags: Nonsymbolic FontBBox: -104, -250, 833, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJODCL+AdvOT5fcf1b24+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JJODCL+AdvOT5fcf1b24+fb Flags: Symbolic FontBBox: 0, 0, 687, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJOALB+AdvOT2bda31c3.B FontSubset: true FirstChar: 65 LastChar: 89 FontDescriptor: FontName: JJOALB+AdvOT2bda31c3.B Flags: Nonsymbolic FontBBox: -41, -250, 885, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJPDLC+AdvOTd0125be5.BI+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JJPDLC+AdvOTd0125be5.BI+fb Flags: Symbolic FontBBox: 0, 0, 885, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJOALA+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 160 FontDescriptor: FontName: JJOALA+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJPEHO+AdvOT3b30f6db.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JJPEHO+AdvOT3b30f6db.B+fb Flags: Symbolic FontBBox: 0, 0, 833, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJPGFE+AdvP4C9542 FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: JJPGFE+AdvP4C9542 Flags: Nonsymbolic FontBBox: 0, -208, 979, 677 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAKP+AdvOT5fcf1b24+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: JJOAKP+AdvOT5fcf1b24+20 Flags: Nonsymbolic FontBBox: -145, -197, 1052, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAKO+AdvOT5fcf1b24 FontSubset: true FirstChar: 37 LastChar: 169 FontDescriptor: FontName: JJOAKO+AdvOT5fcf1b24 Flags: Nonsymbolic FontBBox: -31, -250, 770, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAME+AdvOT1ef757c0 FontSubset: true FirstChar: 37 LastChar: 122 FontDescriptor: FontName: JJOAME+AdvOT1ef757c0 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJPFAL+AdvTT5843c571 FontSubset: true FirstChar: 184 LastChar: 184 FontDescriptor: FontName: JJPFAL+AdvTT5843c571 Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAJO+AdvOTce3d9a73 FontSubset: true FirstChar: 69 LastChar: 122 FontDescriptor: FontName: JJOAJO+AdvOTce3d9a73 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAMG+AdvOT1ef757c0+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: JJOAMG+AdvOT1ef757c0+fb Flags: Symbolic FontBBox: 0, -10, 781, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JJOACP+AdvOT46dcae81 FontSubset: true FirstChar: 44 LastChar: 122 FontDescriptor: FontName: JJOACP+AdvOT46dcae81 Flags: Nonsymbolic FontBBox: -41, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJODCK+AdvOTc20ddc96 FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: JJODCK+AdvOTc20ddc96 Flags: Nonsymbolic FontBBox: -31, -250, 791, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOBHF+AdvOTd0125be5.BI FontSubset: true FirstChar: 44 LastChar: 122 FontDescriptor: FontName: JJOBHF+AdvOTd0125be5.BI Flags: Nonsymbolic FontBBox: -93, -250, 927, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJOAMF+AdvOT1ef757c0+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: JJOAMF+AdvOT1ef757c0+20 Flags: Nonsymbolic FontBBox: -135, -187, 1010, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JJODIL+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JJODIL+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: JJOBHE+AdvP4C9543 FontSubset: true FirstChar: 48 LastChar: 163 FontDescriptor: FontName: JJOBHE+AdvP4C9543 Flags: Nonsymbolic FontBBox: 0, -947, 1041, 895 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf 10.1080/15592294.2017.1318235 en Taylor & Francis Epigenetics, 2017. doi:10.1080/15592294.2017.1318235 DNA repeats epigenetics genome organization macrosatellite repeats noncoding genome Emerging roles of macrosatellite repeats in genome organization and disease development Gabrijela Dumbovic Sonia-V. Forcales Manuel Perucho Journal Epigenetics Copyright Taylor & Francis 1559-2294 1559-2308 12 7 515 526 10.1080/15592294.2017.1318235 https://doi.org/10.1080/15592294.2017.1318235 2017-08-02T07:54:29+05:30 Arbortext Advanced Print Publisher 10.0.1062/W Unicode 2017-08-02T07:55:05+05:30 2017-08-02T07:55:05+05:30 Acrobat Distiller 10.1.10 (Windows) DNA repeats,epigenetics,genome organization,macrosatellite repeats,noncoding genome uuid:6c176206-8560-417f-b9a7-acfa493b47b4 uuid:8fdddd4f-bdb0-4e36-9105-cf32ed0cde67 Pages: Page: Label: 515 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 506, 701, 564, 711 Annotation: Subtype: Link Rect: 133, 638, 137, 648 Destination: null Annotation: Subtype: Link Rect: 214, 638, 218, 648 Destination: null Annotation: Subtype: Link Rect: 313, 638, 316, 648 Destination: null Annotation: Subtype: Link Rect: 316, 638, 318, 649 Destination: null Annotation: Subtype: Link Rect: 318, 638, 322, 648 Destination: null Annotation: Subtype: Link Rect: 291, 350, 300, 360 Destination: null Annotation: Subtype: Link Rect: 206, 279, 220, 288 Destination: null Annotation: Subtype: Link Rect: 186, 195, 189, 205 Destination: null Annotation: Subtype: Link Rect: 218, 183, 221, 193 Destination: null Annotation: Subtype: Link Rect: 277, 135, 280, 145 Destination: null Annotation: Subtype: Link Rect: 296, 87, 300, 97 Destination: null Annotation: Subtype: Link Rect: 469, 315, 476, 324 Destination: null Annotation: Subtype: Link Rect: 483, 310, 505, 320 Destination: 1 Annotation: Subtype: Link Rect: 470, 219, 486, 229 Destination: null Annotation: Subtype: Link Rect: 375, 195, 379, 205 Destination: null Annotation: Subtype: Link Rect: 542, 147, 549, 157 Destination: null Annotation: Subtype: Link Rect: 373, 99, 388, 109 Destination: null Annotation: Subtype: Link Rect: 440, 87, 455, 97 Destination: null Annotation: Subtype: Link Rect: 152, 54, 211, 62 Annotation: Subtype: Link Rect: 424, 37, 560, 44 Annotation: Subtype: Link Rect: 47, 724, 186, 731 Thumb: true Page: Label: 516 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 74, 435, 90, 444 Destination: null Annotation: Subtype: Link Rect: 126, 399, 142, 409 Destination: null Annotation: Subtype: Link Rect: 265, 255, 282, 265 Destination: null Annotation: Subtype: Link Rect: 232, 231, 239, 241 Destination: null Annotation: Subtype: Link Rect: 238, 88, 245, 98 Destination: null Annotation: Subtype: Link Rect: 115, 40, 122, 50 Destination: null Annotation: Subtype: Link Rect: 518, 710, 534, 719 Destination: null Annotation: Subtype: Link Rect: 343, 662, 350, 672 Destination: null Annotation: Subtype: Link Rect: 333, 626, 349, 636 Destination: null Annotation: Subtype: Link Rect: 483, 562, 513, 572 Destination: 27 Annotation: Subtype: Link Rect: 334, 315, 356, 325 Destination: null Annotation: Subtype: Link Rect: 404, 303, 411, 313 Destination: null Annotation: Subtype: Link Rect: 386, 267, 403, 277 Destination: null Annotation: Subtype: Link Rect: 334, 220, 341, 229 Destination: null Annotation: Subtype: Link Rect: 313, 148, 320, 158 Destination: null Annotation: Subtype: Link Rect: 533, 124, 540, 134 Destination: null Thumb: true Page: Label: 517 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 256, 255, 263, 265 Destination: null Annotation: Subtype: Link Rect: 153, 184, 169, 193 Destination: null Annotation: Subtype: Link Rect: 87, 148, 94, 158 Destination: 178 Annotation: Subtype: Link Rect: 156, 148, 163, 158 Destination: 178 Annotation: Subtype: Link Rect: 447, 423, 463, 432 Destination: 178 Annotation: Subtype: Link Rect: 334, 327, 358, 337 Destination: 178 Annotation: Subtype: Link Rect: 379, 303, 386, 313 Destination: 178 Annotation: Subtype: Link Rect: 334, 208, 341, 217 Destination: 232 Annotation: Subtype: Link Rect: 437, 160, 444, 169 Destination: 232 Annotation: Subtype: Link Rect: 540, 682, 559, 689 Destination: null Annotation: Subtype: Link Rect: 543, 637, 555, 644 Destination: 232 Annotation: Subtype: Link Rect: 540, 547, 558, 555 Destination: 292 Annotation: Subtype: Link Rect: 540, 538, 558, 546 Destination: null Thumb: true Page: Label: 518 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 242, 698, 249, 707 Destination: 232 Annotation: Subtype: Link Rect: 107, 657, 129, 667 Destination: 47 Annotation: Subtype: Link Rect: 213, 566, 220, 576 Destination: 232 Annotation: Subtype: Link Rect: 257, 518, 264, 528 Destination: 232 Annotation: Subtype: Link Rect: 103, 483, 110, 492 Destination: 232 Annotation: Subtype: Link Rect: 125, 399, 132, 409 Destination: null Annotation: Subtype: Link Rect: 488, 590, 495, 600 Destination: 232 Annotation: Subtype: Link Rect: 539, 554, 546, 564 Destination: 232 Annotation: Subtype: Link Rect: 316, 494, 331, 504 Destination: 232 Annotation: Subtype: Link Rect: 481, 470, 488, 480 Destination: 232 Annotation: Subtype: Link Rect: 499, 411, 516, 420 Destination: 232 Annotation: Subtype: Link Rect: 363, 363, 379, 372 Destination: 232 Annotation: Subtype: Link Rect: 398, 351, 422, 361 Destination: 232 Annotation: Subtype: Link Rect: 41, 37, 59, 45 Destination: 232 Annotation: Subtype: Link Rect: 75, 37, 82, 45 Destination: 232 Thumb: true Page: Label: 519 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 173, 722, 180, 731 Destination: 232 Annotation: Subtype: Link Rect: 191, 674, 198, 684 Destination: 232 Annotation: Subtype: Link Rect: 174, 562, 195, 572 Destination: 68 Annotation: Subtype: Link Rect: 196, 494, 203, 504 Destination: 232 Annotation: Subtype: Link Rect: 241, 411, 257, 421 Destination: 232 Annotation: Subtype: Link Rect: 131, 375, 138, 385 Destination: 232 Annotation: Subtype: Link Rect: 235, 351, 251, 361 Destination: 232 Annotation: Subtype: Link Rect: 487, 433, 494, 443 Destination: 232 Annotation: Subtype: Link Rect: 461, 374, 469, 383 Destination: 232 Annotation: Subtype: Link Rect: 381, 39, 391, 47 Destination: 232 Thumb: true Page: Label: 520 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 144, 686, 151, 696 Destination: 232 Annotation: Subtype: Link Rect: 218, 686, 225, 696 Destination: 232 Annotation: Subtype: Link Rect: 97, 662, 104, 672 Destination: 232 Annotation: Subtype: Link Rect: 56, 638, 63, 648 Destination: 232 Annotation: Subtype: Link Rect: 162, 614, 169, 624 Destination: 232 Annotation: Subtype: Link Rect: 129, 566, 145, 576 Destination: 232 Annotation: Subtype: Link Rect: 61, 494, 68, 504 Destination: 292 Annotation: Subtype: Link Rect: 413, 698, 420, 707 Destination: 292 Annotation: Subtype: Link Rect: 334, 686, 341, 696 Destination: 292 Annotation: Subtype: Link Rect: 433, 657, 457, 667 Destination: 84 Annotation: Subtype: Link Rect: 442, 602, 449, 612 Destination: 292 Annotation: Subtype: Link Rect: 191, 39, 202, 47 Destination: 292 Thumb: true Page: Label: 521 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 237, 734, 244, 743 Destination: 292 Annotation: Subtype: Link Rect: 235, 722, 242, 731 Destination: 292 Annotation: Subtype: Link Rect: 255, 590, 262, 600 Destination: 292 Annotation: Subtype: Link Rect: 178, 578, 185, 588 Destination: 292 Annotation: Subtype: Link Rect: 80, 542, 96, 552 Destination: 292 Annotation: Subtype: Link Rect: 143, 494, 150, 504 Destination: 292 Annotation: Subtype: Link Rect: 214, 447, 221, 456 Destination: 292 Annotation: Subtype: Link Rect: 210, 411, 217, 421 Destination: 292 Annotation: Subtype: Link Rect: 203, 291, 210, 301 Destination: 292 Annotation: Subtype: Link Rect: 192, 243, 208, 253 Destination: 292 Annotation: Subtype: Link Rect: 66, 184, 73, 193 Destination: 292 Annotation: Subtype: Link Rect: 199, 88, 223, 98 Destination: null Annotation: Subtype: Link Rect: 185, 64, 196, 74 Destination: 292 Annotation: Subtype: Link Rect: 551, 614, 561, 624 Destination: 292 Annotation: Subtype: Link Rect: 553, 602, 564, 612 Destination: 292 Annotation: Subtype: Link Rect: 520, 590, 531, 600 Destination: 292 Annotation: Subtype: Link Rect: 398, 566, 408, 576 Destination: 292 Annotation: Subtype: Link Rect: 371, 506, 381, 516 Destination: 292 Annotation: Subtype: Link Rect: 361, 483, 372, 492 Destination: 292 Annotation: Subtype: Link Rect: 355, 411, 366, 421 Destination: 292 Annotation: Subtype: Link Rect: 390, 315, 401, 325 Destination: 292 Thumb: true Page: Label: 522 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 62, 698, 73, 707 Destination: 292 Annotation: Subtype: Link Rect: 237, 578, 256, 588 Destination: null Annotation: Subtype: Link Rect: 103, 459, 110, 468 Destination: null Annotation: Subtype: Link Rect: 173, 339, 183, 349 Destination: 292 Annotation: Subtype: Link Rect: 184, 231, 194, 241 Destination: 292 Annotation: Subtype: Link Rect: 208, 196, 231, 205 Destination: 292 Annotation: Subtype: Link Rect: 186, 76, 196, 86 Destination: 292 Thumb: true Page: Label: 523 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 80, 650, 91, 660 Destination: 292 Annotation: Subtype: Link Rect: 236, 471, 247, 480 Destination: 292 Annotation: Subtype: Link Rect: 90, 81, 258, 90 Annotation: Subtype: Link Rect: 90, 51, 260, 60 Annotation: Subtype: Link Rect: 506, 720, 564, 728 Annotation: Subtype: Link Rect: 331, 710, 419, 718 Annotation: Subtype: Link Rect: 392, 690, 536, 698 Annotation: Subtype: Link Rect: 331, 670, 430, 678 Annotation: Subtype: Link Rect: 470, 640, 564, 648 Annotation: Subtype: Link Rect: 331, 630, 433, 638 Annotation: Subtype: Link Rect: 445, 600, 564, 609 Annotation: Subtype: Link Rect: 331, 590, 389, 599 Annotation: Subtype: Link Rect: 408, 560, 552, 569 Annotation: Subtype: Link Rect: 446, 530, 564, 539 Annotation: Subtype: Link Rect: 331, 520, 390, 529 Annotation: Subtype: Link Rect: 498, 500, 559, 509 Annotation: Subtype: Link Rect: 454, 471, 564, 479 Annotation: Subtype: Link Rect: 331, 461, 399, 469 Annotation: Subtype: Link Rect: 445, 431, 550, 439 Annotation: Subtype: Link Rect: 353, 401, 516, 409 Annotation: Subtype: Link Rect: 533, 381, 564, 389 Annotation: Subtype: Link Rect: 331, 371, 465, 379 Annotation: Subtype: Link Rect: 494, 351, 564, 360 Annotation: Subtype: Link Rect: 331, 341, 406, 350 Annotation: Subtype: Link Rect: 354, 301, 499, 310 Annotation: Subtype: Link Rect: 353, 261, 510, 270 Annotation: Subtype: Link Rect: 331, 231, 414, 240 Annotation: Subtype: Link Rect: 397, 202, 552, 210 Annotation: Subtype: Link Rect: 476, 182, 564, 190 Annotation: Subtype: Link Rect: 331, 172, 433, 180 Annotation: Subtype: Link Rect: 354, 142, 498, 150 Annotation: Subtype: Link Rect: 449, 112, 564, 120 Annotation: Subtype: Link Rect: 331, 102, 383, 110 Annotation: Subtype: Link Rect: 354, 62, 520, 71 Thumb: true Page: Label: 524 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 72, 700, 273, 708 Annotation: Subtype: Link Rect: 97, 650, 237, 658 Annotation: Subtype: Link Rect: 219, 610, 282, 619 Annotation: Subtype: Link Rect: 49, 600, 152, 609 Annotation: Subtype: Link Rect: 115, 570, 276, 579 Annotation: Subtype: Link Rect: 167, 550, 282, 559 Annotation: Subtype: Link Rect: 49, 540, 99, 549 Annotation: Subtype: Link Rect: 187, 510, 282, 519 Annotation: Subtype: Link Rect: 49, 500, 136, 509 Annotation: Subtype: Link Rect: 71, 451, 216, 459 Annotation: Subtype: Link Rect: 72, 421, 238, 429 Annotation: Subtype: Link Rect: 72, 391, 256, 399 Annotation: Subtype: Link Rect: 72, 341, 261, 350 Annotation: Subtype: Link Rect: 190, 311, 282, 320 Annotation: Subtype: Link Rect: 49, 301, 151, 310 Annotation: Subtype: Link Rect: 71, 241, 240, 250 Annotation: Subtype: Link Rect: 138, 202, 282, 210 Annotation: Subtype: Link Rect: 49, 192, 93, 200 Annotation: Subtype: Link Rect: 120, 142, 282, 150 Annotation: Subtype: Link Rect: 49, 132, 77, 140 Annotation: Subtype: Link Rect: 72, 102, 226, 110 Annotation: Subtype: Link Rect: 251, 82, 282, 90 Annotation: Subtype: Link Rect: 49, 72, 165, 81 Annotation: Subtype: Link Rect: 460, 730, 546, 738 Annotation: Subtype: Link Rect: 313, 720, 400, 728 Annotation: Subtype: Link Rect: 411, 700, 546, 708 Annotation: Subtype: Link Rect: 313, 690, 393, 698 Annotation: Subtype: Link Rect: 399, 690, 461, 698 Annotation: Subtype: Link Rect: 467, 690, 515, 698 Annotation: Subtype: Link Rect: 413, 640, 546, 648 Annotation: Subtype: Link Rect: 313, 630, 345, 638 Annotation: Subtype: Link Rect: 484, 600, 546, 609 Annotation: Subtype: Link Rect: 313, 590, 450, 599 Annotation: Subtype: Link Rect: 472, 540, 546, 549 Annotation: Subtype: Link Rect: 313, 530, 413, 539 Annotation: Subtype: Link Rect: 452, 481, 546, 489 Annotation: Subtype: Link Rect: 313, 471, 403, 479 Annotation: Subtype: Link Rect: 517, 421, 546, 429 Annotation: Subtype: Link Rect: 313, 411, 367, 419 Annotation: Subtype: Link Rect: 472, 361, 546, 369 Annotation: Subtype: Link Rect: 313, 351, 383, 360 Annotation: Subtype: Link Rect: 336, 291, 513, 300 Annotation: Subtype: Link Rect: 348, 241, 518, 250 Annotation: Subtype: Link Rect: 483, 202, 546, 210 Annotation: Subtype: Link Rect: 313, 192, 431, 200 Annotation: Subtype: Link Rect: 336, 142, 495, 150 Annotation: Subtype: Link Rect: 453, 92, 546, 100 Annotation: Subtype: Link Rect: 313, 82, 409, 90 Thumb: true Page: Label: 525 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 205, 730, 300, 738 Annotation: Subtype: Link Rect: 67, 720, 141, 728 Annotation: Subtype: Link Rect: 168, 690, 300, 698 Annotation: Subtype: Link Rect: 67, 680, 144, 688 Annotation: Subtype: Link Rect: 265, 640, 300, 648 Annotation: Subtype: Link Rect: 67, 630, 220, 638 Annotation: Subtype: Link Rect: 126, 590, 291, 599 Annotation: Subtype: Link Rect: 90, 530, 250, 539 Annotation: Subtype: Link Rect: 137, 481, 300, 489 Annotation: Subtype: Link Rect: 67, 471, 114, 479 Annotation: Subtype: Link Rect: 177, 421, 300, 429 Annotation: Subtype: Link Rect: 67, 411, 110, 419 Annotation: Subtype: Link Rect: 269, 381, 300, 389 Annotation: Subtype: Link Rect: 67, 371, 187, 379 Annotation: Subtype: Link Rect: 225, 351, 300, 360 Annotation: Subtype: Link Rect: 67, 341, 142, 350 Annotation: Subtype: Link Rect: 90, 301, 239, 310 Annotation: Subtype: Link Rect: 160, 261, 300, 270 Annotation: Subtype: Link Rect: 67, 251, 131, 260 Annotation: Subtype: Link Rect: 179, 212, 300, 220 Annotation: Subtype: Link Rect: 67, 202, 114, 210 Annotation: Subtype: Link Rect: 177, 172, 300, 180 Annotation: Subtype: Link Rect: 67, 162, 115, 170 Annotation: Subtype: Link Rect: 238, 132, 300, 140 Annotation: Subtype: Link Rect: 67, 122, 181, 130 Annotation: Subtype: Link Rect: 139, 82, 276, 90 Annotation: Subtype: Link Rect: 90, 52, 287, 61 Annotation: Subtype: Link Rect: 529, 700, 564, 708 Annotation: Subtype: Link Rect: 331, 690, 453, 698 Annotation: Subtype: Link Rect: 476, 660, 564, 668 Annotation: Subtype: Link Rect: 331, 650, 417, 658 Annotation: Subtype: Link Rect: 354, 610, 535, 619 Annotation: Subtype: Link Rect: 502, 570, 564, 579 Annotation: Subtype: Link Rect: 331, 560, 440, 569 Annotation: Subtype: Link Rect: 365, 520, 531, 529 Annotation: Subtype: Link Rect: 354, 481, 513, 489 Annotation: Subtype: Link Rect: 533, 451, 564, 459 Annotation: Subtype: Link Rect: 331, 441, 522, 449 Annotation: Subtype: Link Rect: 528, 441, 564, 449 Annotation: Subtype: Link Rect: 331, 431, 352, 439 Annotation: Subtype: Link Rect: 359, 431, 396, 439 Annotation: Subtype: Link Rect: 474, 391, 564, 399 Annotation: Subtype: Link Rect: 331, 381, 400, 389 Annotation: Subtype: Link Rect: 354, 331, 551, 340 Annotation: Subtype: Link Rect: 502, 271, 564, 280 Annotation: Subtype: Link Rect: 331, 261, 471, 270 Annotation: Subtype: Link Rect: 529, 222, 564, 230 Annotation: Subtype: Link Rect: 331, 212, 441, 220 Annotation: Subtype: Link Rect: 354, 162, 513, 170 Annotation: Subtype: Link Rect: 355, 112, 564, 120 Annotation: Subtype: Link Rect: 331, 102, 350, 110 Annotation: Subtype: Link Rect: 356, 102, 438, 110 Annotation: Subtype: Link Rect: 444, 102, 491, 110 Annotation: Subtype: Link Rect: 366, 72, 562, 81 Thumb: true Page: Label: 526 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 72, 720, 268, 728 Annotation: Subtype: Link Rect: 188, 680, 282, 688 Annotation: Subtype: Link Rect: 49, 670, 137, 678 Annotation: Subtype: Link Rect: 253, 620, 282, 629 Annotation: Subtype: Link Rect: 49, 610, 117, 619 Annotation: Subtype: Link Rect: 165, 570, 282, 579 Annotation: Subtype: Link Rect: 49, 560, 107, 569 Annotation: Subtype: Link Rect: 247, 530, 282, 539 Annotation: Subtype: Link Rect: 49, 520, 168, 529 Annotation: Subtype: Link Rect: 251, 491, 282, 499 Annotation: Subtype: Link Rect: 49, 481, 181, 489 Annotation: Subtype: Link Rect: 72, 441, 237, 449 Annotation: Subtype: Link Rect: 247, 401, 282, 409 Annotation: Subtype: Link Rect: 49, 391, 181, 399 Annotation: Subtype: Link Rect: 206, 361, 282, 369 Annotation: Subtype: Link Rect: 49, 351, 158, 360 Annotation: Subtype: Link Rect: 206, 311, 282, 320 Annotation: Subtype: Link Rect: 49, 301, 154, 310 Annotation: Subtype: Link Rect: 101, 261, 262, 270 Annotation: Subtype: Link Rect: 192, 222, 282, 230 Annotation: Subtype: Link Rect: 49, 212, 143, 220 Annotation: Subtype: Link Rect: 247, 192, 282, 200 Annotation: Subtype: Link Rect: 49, 182, 160, 190 Annotation: Subtype: Link Rect: 100, 152, 210, 160 Annotation: Subtype: Link Rect: 72, 122, 228, 130 Annotation: Subtype: Link Rect: 167, 92, 282, 100 Annotation: Subtype: Link Rect: 49, 82, 130, 90 Annotation: Subtype: Link Rect: 335, 690, 491, 698 Annotation: Subtype: Link Rect: 348, 640, 513, 648 Annotation: Subtype: Link Rect: 375, 600, 531, 609 Annotation: Subtype: Link Rect: 456, 570, 485, 579 Annotation: Subtype: Link Rect: 336, 520, 526, 529 Annotation: Subtype: Link Rect: 511, 481, 546, 489 Annotation: Subtype: Link Rect: 313, 471, 432, 479 Annotation: Subtype: Link Rect: 434, 431, 462, 439 Annotation: Subtype: Link Rect: 511, 381, 546, 389 Annotation: Subtype: Link Rect: 313, 371, 466, 379 Annotation: Subtype: Link Rect: 480, 341, 546, 350 Annotation: Subtype: Link Rect: 313, 331, 427, 340 Annotation: Subtype: Link Rect: 336, 271, 532, 280 Annotation: Subtype: Link Rect: 485, 231, 546, 240 Annotation: Subtype: Link Rect: 313, 222, 402, 230 Annotation: Subtype: Link Rect: 421, 172, 546, 180 Annotation: Subtype: Link Rect: 313, 162, 359, 170 Annotation: Subtype: Link Rect: 377, 122, 546, 130 Annotation: Subtype: Link Rect: 313, 112, 335, 120 Annotation: Subtype: Link Rect: 456, 92, 546, 100 Annotation: Subtype: Link Rect: 313, 82, 403, 90 Thumb: true Checksum: 5ac00b17 Type: CRC32 Checksum: e6316789b13f18f1503336c54c4376e1 Type: MD5 Checksum: 1fb95cf7813bef7c904115f4763067893471f17e Type: SHA-1