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MIMEtype: application/pdf PDFMetadata: Objects: 762 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Background Destination: sectionASec1 Item: Title: Results Destination: sectionASec2 Item: Title: Conclusions Destination: sectionASec3 Item: Title: Background Destination: sectionSec1 Item: Title: Results Destination: sectionSec2 Children: Item: Title: Genomic differentiation of Phaseolus species Destination: sectionSec3 Item: Title: Uncovering the closest sister clade of P. vulgaris Destination: sectionSec4 Item: Title: Metabolomic profiling differentiates Phaseolus species and implicates flavonoid production as a phenomenon accompanying species radiation Destination: sectionSec5 Item: Title: Asymmetric intra-species and inter-species genomic flow in Mesoamerica and across hemispheres Destination: sectionSec6 Item: Title: Parallel domestication events share signatures of selection in both common bean gene pools Destination: sectionSec7 Item: Title: Differential shaping of the common bean genome by domestication and genomic introgression Destination: sectionSec8 Item: Title: Discussion Destination: sectionSec9 Children: Item: Title: P. pseudovulgaris emerged by allopatric speciation in the Amotape–Huancabamba Depression before the split of both P. vulgaris gene pools Destination: sectionSec10 Item: Title: Insights into genetic barriers for reproduction in the genus Destination: sectionSec11 Item: Title: Modern cultivars result from the combined outcome of domestication and adaptive introgressions Destination: sectionSec12 Item: Title: Conclusions Destination: sectionSec13 Item: Title: Methods Destination: sectionSec14 Children: Item: Title: Plant material Destination: sectionSec15 Item: Title: DNA/RNA sequencing and mapping Destination: sectionSec16 Item: Title: Nuclear and chloroplast phylogenetic profiles Destination: sectionSec17 Item: Title: Coalescent simulations Destination: sectionSec18 Item: Title: Introgression signal Destination: sectionSec19 Item: Title: Selection during domestication Destination: sectionSec20 Item: Title: Gene Ontology enrichments Destination: sectionSec21 Item: Title: Sample preparation and extraction for metabolomic profiling Destination: sectionSec22 Item: Title: Mass spectrometry Destination: sectionSec23 Item: Title: Non-targeted metabolite profiling Destination: sectionSec24 Item: Title: Metabolomic data analysis Destination: sectionSec25 Item: Title: Additional files Destination: sectionSec26 Item: Title: Acknowledgments Destination: sections13059-017-1190-6 Item: Title: Funding Destination: sectionFPar1 Item: Title: Availability of data and materials Destination: sectionFPar2 Item: Title: Authors’ contributions Destination: sectionFPar3 Item: Title: Competing interests Destination: sectionFPar4 Item: Title: Ethics approval and consent to participate Destination: 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