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Item: Title: Methods Destination: sectionSec2 Children: Item: Title: Design and setting Destination: sectionSec3 Item: Title: Measures Destination: sectionSec4 Item: Title: Statistical analysis Destination: sectionSec5 Item: Title: Results Destination: sectionSec6 Children: Item: Title: Latent classes of multimorbidity pattern Destination: sectionSec7 Item: Title: Association between multimorbidity classes with outcomes at baseline and after 3 years Destination: sectionSec8 Item: Title: Sensitivity analysis Destination: sectionSec9 Item: Title: Discussion Destination: sectionSec10 Item: Title: Conclusions Destination: sectionSec11 Item: Title: Additional files Destination: sectionSec100 Item: Title: Abbreviations Destination: sectionabr1 Item: Title: Funding Destination: sectionFPar4 Item: Title: Availability of data and materials Destination: sectionFPar1 Item: Title: Authors’ contributions Destination: sections12877-017-0586-1 Item: Title: Ethics approval and consent to participate 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