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Subject: npjParkinson’s Disease, doi:10.1038/s41531-017-0030-4 Keywords: Author: Miguel Rosa-Grilo Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Mon Aug 28 13:31:15 2017 CEST ModDate: Wed Aug 30 15:51:37 2017 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1094901 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- CDIBPG+AdvTT5afe5d37.B Type 1C WinAnsi yes yes no 539 0 AFUAVX+Arial-BoldMT Type 1C WinAnsi yes yes no 540 0 CDICJF+AdvOTa20b42a7 Type 1C WinAnsi yes yes no 541 0 CDICOK+AdvOT65f8a23b.I+20 Type 1C WinAnsi yes yes no 542 0 CDICJG+AdvOTa20b42a7+20 Type 1C WinAnsi yes yes no 543 0 CDICOL+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 303 0 CDICKG+AdvTT6780a46b Type 1C WinAnsi yes yes no 179 0 CDICNG+AdvOT46dcae81 Type 1C WinAnsi yes yes no 134 0 CDICOJ+AdvOT65f8a23b.I Type 1C WinAnsi yes yes no 136 0 CDICNI+AdvOT46dcae81+fb Type 1C Custom yes yes yes 137 0 CDIDCK+AdvMyriad_R Type 1C WinAnsi yes yes no 138 0 CDICNH+AdvOT46dcae81+20 Type 1C WinAnsi yes yes no 139 0 CDIEIE+AdvOT7d2ebc01 Type 1C WinAnsi yes yes no 135 0 CDIEEE+AdvOT46dcae81+03 Type 1C Custom yes yes yes 140 0 CDIEJF+AdvOT46dcae81+22 Type 1C Custom yes yes no 180 0 CDIEKH+AdvTT6780a46b+20 Type 1C WinAnsi yes yes no 181 0 CDIEKI+AdvOT8608a8d1 Type 1C WinAnsi yes yes no 182 0 CDIEJG+AdvOT919a0533.B Type 1C WinAnsi yes yes no 183 0 CDIEKG+AdvTT6780a46b+fb Type 1C Custom yes yes yes 184 0 CDIFAH+AdvOT8608a8d1+22 Type 1C Custom yes yes yes 207 0 CDIMAN+AdvOT3b30f6db.B+20 Type 1C WinAnsi yes yes no 318 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-02-08 02:58:19 CET RepresentationInformation: 288453.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-02-07 11:02:34 CET Size: 1094901 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 606 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Rotigotine transdermal patch and sleep in Parkinson’s disease: where are we now? Destination: title_link Children: Item: Title: Introduction Destination: A1 Children: Item: Title: Night-time sleep disturbances in Parkinson’s disease Destination: B1 Item: Title: Rotigotine pharmacology and why it may help with sleep related problems in Parkinson’s disease Destination: B2 Item: Title: Sleep fragmentation Destination: B3 Item: Title: Restless legs syndrome Destination: B4 Item: Title: Nocturia Destination: B5 Item: Title: Nocturnal pain Destination: B6 Item: Title: REM sleep behavior disorder Destination: B7 Item: Title: Rotigotine in apomorphine or other advanced therapies treated advanced Parkinson’s patients Destination: B8 Item: Title: Possible adverse sleep related events Destination: B9 Item: Title: Conclusion Destination: A2 Children: Item: Title: Suggested specific clinical uses Destination: B10 Item: Title: Acknowledgements Destination: A3 Item: Title: Author contributions Destination: A4 Item: Title: Competing interests Destination: A5 Item: Title: ACKNOWLEDGMENTS Destination: M1 Info: Title: Rotigotine transdermal patch and sleep in Parkinson’s disease: where are we now? Author: Miguel Rosa-Grilo Subject: npjParkinson’s Disease, doi:10.1038/s41531-017-0030-4 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Mon Aug 28 14:01:15 CEST 2017 ModDate: Wed Aug 30 15:51:37 CEST 2017 ID: 0x25107b411ed8d7f941cb3dccd2c96e50, 0x15e78d086ec1dc33280f7998b857378e Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 250 ImageHeight: 95 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1500 ImageHeight: 1156 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg 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application/pdf doi:10.1038/s41531-017-0030-4 Rotigotine transdermal patch and sleep in Parkinson’s disease: where are we now? Miguel Rosa-Grilo Mubasher A. Qamar Raquel N. Taddei Javier Pagonabarraga Jaime Kulisevsky Anna Sauerbier K. Ray Chaudhuri Springer US npjParkinson’s Disease, doi:10.1038/s41531-017-0030-4 10.1038/s41531-017-0030-4 http://dx.doi.org/10.1038/s41531-017-0030-4 journal npjParkinson’s Disease © 2017, The Author(s) 2373-8057 10.1038/s41531-017-0030-4 springer.com springerlink.com 2010-04-23 True 10.1038/s41531-017-0030-4 springer.com springerlink.com Springer 2017-08-30T15:51:37+02:00 2017-08-28T17:01:15+05:30 2017-08-30T15:51:37+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) VoR uuid:429d4a39-2516-4f8a-a5bb-d1662793db33 uuid:d155ebdf-6d6f-43c5-b337-82adcdb9d6c3 default 1 converted uuid:b1c3c03b-0bf3-44cc-84e5-e188e9b55bae converted to PDF/A-2b pdfToolbox 2017-08-28T17:02:02+05:30 2 B Mubasher A. Qamar http://orcid.org/0000-0002-4105-5097 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. 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