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Item: Title: CSF-1 and IL-10 upregulates CCR5 expression. Item: Title: Effects of IL-10 and CSF-1 on monocytes from CD patients and HD. Item: Title: CCL5/CCR5 signaling modifies phenotype during the maturation of monocytes from HD and CD patients. Item: Title: CCL5 suppressed LPS-induced IL-6 and TNF-α production by CD monocytes. Item: Title: CCR5 expression and CSF-1 were associated with clinical behavior and treatment in CD patients in remission. Item: Title: Discussion Item: Title: Material and Methods Children: Item: Title: Patients and Samples. Item: Title: Ethical statement. Item: Title: Reagents. Item: Title: Whole blood cell culture. Item: Title: Whole blood cell staining and flow cytometry analysis. Item: Title: Determination of cytokine plasma levels. Item: Title: Chemotaxis assay. Item: Title: Statistics. Item: Title: Acknowledgements Item: Title: Figure 1 CCR5 expression on monocytes from HD and CD patients in remission. Item: Title: Figure 2 CSF-1 and IL-10 upregulated CCR5 expression on monocytes from HD and CD patients in remission. Item: Title: Figure 3 Functional effects of CSF-1 and IL-10 on peripheral blood monocytes from HD and CD patients in remission. Item: Title: Figure 4 CCL5/CCR5 signaling modified the phenotype of monocytes during their maturation. Item: Title: Figure 5 CCL5 suppressed LPS-induced IL-6 and TNF-α production by peripheral blood monocytes from HD and CD patients in remission. Item: Title: Figure 6 CSF-1 and CCR5 expression was associated with clinical behavior and treatment in CD patients in remission. Item: Title: Table 1 Clinical characteristics of the Crohn’s disease study population. 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FontBBox: -553, -239, 1110, 952 FontFile2: true XMP: application/pdf doi:10.1038/s41598-017-00145-4 CSF-1 regulates the function of monocytes in Crohn’s disease patients in remission Juan Camilo Nieto Carlos Zamora Elisabet Cantamp#x000F3; Esther Garcia-Planella Jordi Gordillo Maria Angels Ortiz Camp#x000E1;ndido Juamp#x000E1;rez Silvia Vidal Springer US Scientific Reports, doi:10.1038/s41598-017-00145-4 10.1038/s41598-017-00145-4 http://dx.doi.org/10.1038/s41598-017-00145-4 journal Scientific Reports © 2017, The Author(s) 2045-2322 1 11 noindex 10.1038/s41598-017-00145-4 2010-04-23 springer.com springerlink.com 2010-04-23 True 10.1038/s41598-017-00145-4 springer.com springerlink.com Springer 2017-03-01T15:02:49+01:00 2017-02-28T15:25:17+05:30 2017-03-01T15:02:49+01:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) uuid:0b6b4ced-1015-4793-b317-3cf13379d75d uuid:8b7a75f9-113b-42c1-8a5f-63ad49ae616c Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 363, 300, 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