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Keywords: angiogenesis, atherosclerosis, cardiovascular diseases, cell-derived microvesicles, endothelial dysfunction, inflammation, neovascularization, thrombosis Author: Lina Badimon Creator: Adobe InDesign CS6 (Windows) Producer: Adobe PDF Library 10.0.1 CreationDate: Wed Dec 13 14:50:37 2017 CET ModDate: Thu Dec 14 10:51:14 2017 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 20 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 2136974 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XNNYGO+HelveticaNeueLTStd-Lt Type 1C Custom yes yes yes 1629 0 SQYPOY+EuclidExtra CID TrueType Identity-H yes yes yes 1646 0 XNNYGO+HelveticaNeueLTStd-Bd Type 1C Custom yes yes yes 1630 0 IOAMES+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes yes 1638 0 IOAMES+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes yes 1639 0 IOAMES+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes yes 1640 0 IOAMES+MinionPro-Bold Type 1C Custom yes yes yes 1647 0 SQYPOY+MinionPro-Regular Type 1C Custom yes yes yes 1648 0 CNWXYE+MinionPro-It Type 1C Custom yes yes yes 1576 0 CNWXYE+STIXGeneral-Regular Type 1C Custom yes yes yes 1564 0 XNNYGO+HelveticaNeueLTStd-Lt Type 1C WinAnsi yes yes yes 1577 0 XNNYGO+HelveticaNeueLTStd-Lt Type 1C WinAnsi yes yes yes 1581 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-02-29 02:49:41 CET RepresentationInformation: 289307.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-02-28 13:50:40 CET Size: 2136974 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1747 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Microvesicles in Atherosclerosis and Angiogenesis: From Bench to Bedside and Reverse Children: Item: Title: Introduction Item: Title: MV-Mediated Regulatory Mechanisms in the Development and Progression of AT Children: Item: Title: Endothelial Dysfunction Item: Title: Vascular Wall Atheroinflammation Item: Title: Oxidative Stress, Apoptosis, and Vascular Remodeling Item: Title: Coagulation and Thrombosis Item: Title: Potential Prognostic, Diagnostic, and Therapeutic Value of Cell-Derived MVs in AT Children: Item: Title: Cardiovascular Risk Factors Item: Title: Atherosclerosis Item: Title: Acute Coronary Syndromes Item: Title: Cerebrovascular Disease Item: Title: AT-Driven Angiogenesis and Neovascularization: MVs as Therapeutic Vectors Item: Title: Pharmacological and Non-Pharmacological Intervention Children: Item: Title: Therapeutic Potential Item: Title: Conclusion and Future Perspectives Item: Title: Author Contributions Item: Title: Acknowledgments Item: Title: Funding Item: Title: References Info: Title: Microvesicles in Atherosclerosis and Angiogenesis: From Bench to Bedside and Reverse Author: Lina Badimon Subject: Atherosclerosis (AT) is a progressive chronic disease involving lipid accumulation, fibrosis, and inflammation in medium and large-sized arteries, and it is the main cause of cardiovascular disease (CVD). 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