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Keywords: Myc, oncogene, inhibitor, therapy, Omomyc, clinical application Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Feb 20 11:23:39 CET 2017 ModDate: Mon Feb 20 11:27:46 CET 2017 ID: 0xf809bdcf20e1e09f40ceeffb8ff55a3e, 0xd4b2d31098660c49aae2c9c55dc22ca2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 506 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 525 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1784 ImageHeight: 812 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: JVXNZG+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 0 LastChar: 121 FontDescriptor: FontName: JVXNZG+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -64, -205, 995, 731 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PHVTDT+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: PHVTDT+HelveticaNeueLTStd-Bd Flags: Serif, Nonsymbolic FontBBox: -8, -214, 848, 786 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IOLGNI+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: IOLGNI+MTGU Flags: Symbolic FontBBox: 0, -188, 607, 460 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: DZIQUZ+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: DZIQUZ+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ZRFSYQ+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: ZRFSYQ+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -30, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: TPUWOU+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: TPUWOU+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 823, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: RVBXPV+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: RVBXPV+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 856, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IKZHMO+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: IKZHMO+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MJPKHX+RMTMI FontSubset: true FirstChar: 22 LastChar: 22 FontDescriptor: FontName: MJPKHX+RMTMI Flags: Symbolic FontBBox: 0, -188, 637, 440 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: TWTZSH+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 169 FontDescriptor: FontName: TWTZSH+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 1003, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: UOTLLQ+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 0 LastChar: 122 FontDescriptor: FontName: UOTLLQ+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: 0, -205, 815, 731 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CNTUYP+MTSY FontSubset: true FirstChar: 48 LastChar: 48 FontDescriptor: FontName: CNTUYP+MTSY Flags: Symbolic FontBBox: 0, 0, 279, 553 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: dvips + MiKTeX GPL Ghostscript 9.0 Myc, oncogene, inhibitor, therapy, Omomyc, clinical application 2017-02-20T15:27:46+05:30 2017-02-20T15:23:39+05:30 LaTeX with hyperref package + hypdvips 2017-02-20T15:27:46+05:30 f41f2ac4-f9ad-11e6-0000-8232e01dfb52 uuid:b4f3f84c-88de-42c8-b87c-2ee4a1755a98 application/pdf Strategies to Inhibit Myc and Their Clinical Applicability Laura Soucek Myc is an oncogene deregulated in most—perhaps all—human cancers. Myc is an oncogene deregulated in most—perhaps all—human cancers. 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External Annotation: Subtype: Link Rect: 425, 90, 467, 101 Destination: External Annotation: Subtype: Link Rect: 471, 90, 491, 101 Destination: External Annotation: Subtype: Link Rect: 406, 67, 446, 78 Destination: External Annotation: Subtype: Link Rect: 448, 67, 468, 78 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 96, 528, 86, 586 Destination: External Annotation: Subtype: Link Rect: 96, 587, 86, 605 Destination: External Annotation: Subtype: Link Rect: 96, 607, 86, 644 Destination: External Annotation: Subtype: Link Rect: 96, 646, 86, 664 Destination: External Annotation: Subtype: Link Rect: 107, 528, 97, 555 Destination: External Annotation: Subtype: Link Rect: 107, 557, 97, 575 Destination: External Annotation: Subtype: Link Rect: 107, 577, 97, 615 Destination: External Annotation: Subtype: Link Rect: 107, 617, 97, 635 Destination: External Annotation: Subtype: Link Rect: 107, 637, 97, 665 Destination: External Annotation: Subtype: Link Rect: 107, 667, 97, 684 Destination: External Annotation: Subtype: Link Rect: 107, 686, 107, 544 Destination: External Annotation: Subtype: Link Rect: 116, 546, 107, 564 Destination: External Annotation: Subtype: Link Rect: 133, 528, 123, 564 Destination: External Annotation: Subtype: Link Rect: 133, 566, 123, 584 Destination: External Annotation: Subtype: Link Rect: 144, 528, 134, 559 Destination: External Annotation: Subtype: Link Rect: 144, 561, 134, 579 Destination: External Annotation: Subtype: Link Rect: 144, 581, 134, 628 Destination: External Annotation: Subtype: Link Rect: 144, 630, 134, 647 Destination: External Annotation: Subtype: Link Rect: 144, 649, 134, 667 Destination: External Annotation: Subtype: Link Rect: 144, 669, 134, 686 Destination: External Annotation: Subtype: Link Rect: 160, 528, 151, 568 Destination: External Annotation: Subtype: Link Rect: 160, 570, 151, 587 Destination: External Annotation: Subtype: Link Rect: 172, 528, 162, 567 Destination: External Annotation: Subtype: Link Rect: 172, 568, 162, 586 Destination: External Annotation: Subtype: Link Rect: 172, 588, 162, 618 Destination: External Annotation: Subtype: Link Rect: 172, 620, 162, 637 Destination: External Annotation: Subtype: Link Rect: 172, 639, 162, 676 Destination: External Annotation: Subtype: Link Rect: 172, 678, 162, 696 Destination: External Annotation: Subtype: Link Rect: 183, 528, 174, 551 Destination: External Annotation: Subtype: Link Rect: 183, 553, 174, 571 Destination: External Annotation: Subtype: Link Rect: 203, 528, 194, 556 Destination: External Annotation: Subtype: Link Rect: 203, 558, 194, 575 Destination: External Annotation: Subtype: Link Rect: 203, 577, 194, 607 Destination: External Annotation: Subtype: Link Rect: 203, 608, 194, 626 Destination: External Annotation: Subtype: Link Rect: 203, 628, 194, 664 Destination: External Annotation: Subtype: Link Rect: 203, 665, 194, 683 Destination: External Annotation: Subtype: Link Rect: 203, 685, 203, 544 Destination: External Annotation: Subtype: Link Rect: 213, 546, 203, 564 Destination: External Annotation: Subtype: Link Rect: 225, 528, 215, 566 Destination: External Annotation: Subtype: Link Rect: 225, 568, 215, 585 Destination: External Annotation: Subtype: Link Rect: 225, 587, 215, 619 Destination: External Annotation: Subtype: Link Rect: 225, 620, 215, 638 Destination: External Annotation: Subtype: Link Rect: 225, 640, 215, 692 Destination: External Annotation: Subtype: Link Rect: 225, 694, 215, 711 Destination: External Annotation: Subtype: Link Rect: 241, 528, 232, 565 Destination: External Annotation: Subtype: Link Rect: 241, 567, 232, 584 Destination: External Annotation: Subtype: Link Rect: 241, 586, 232, 617 Destination: External Annotation: Subtype: Link Rect: 241, 618, 232, 636 Destination: External Annotation: Subtype: Link Rect: 277, 528, 267, 569 Destination: External Annotation: Subtype: Link Rect: 277, 571, 267, 589 Destination: External Annotation: Subtype: Link Rect: 277, 590, 267, 608 Destination: External Annotation: Subtype: Link Rect: 277, 610, 267, 644 Destination: External Annotation: Subtype: Link Rect: 277, 646, 267, 663 Destination: External Annotation: Subtype: Link Rect: 277, 665, 267, 706 Destination: External Annotation: Subtype: Link Rect: 286, 528, 277, 546 Destination: External Annotation: Subtype: Link Rect: 286, 547, 277, 589 Destination: External Annotation: Subtype: Link Rect: 286, 591, 277, 609 Destination: External Annotation: Subtype: Link Rect: 286, 610, 277, 650 Destination: External Annotation: Subtype: Link Rect: 286, 652, 277, 669 Destination: External Annotation: Subtype: Link Rect: 298, 528, 288, 551 Destination: External Annotation: Subtype: Link Rect: 298, 553, 288, 571 Destination: External Annotation: Subtype: Link Rect: 298, 573, 288, 612 Destination: External Annotation: Subtype: Link Rect: 298, 614, 288, 632 Destination: External Annotation: Subtype: Link Rect: 298, 634, 288, 651 Destination: External Annotation: Subtype: Link Rect: 317, 528, 308, 553 Destination: External Annotation: Subtype: Link Rect: 317, 555, 308, 572 Destination: External Annotation: Subtype: Link Rect: 328, 528, 319, 570 Destination: External Annotation: Subtype: Link Rect: 328, 572, 319, 590 Destination: External Annotation: Subtype: Link Rect: 340, 528, 330, 567 Destination: External Annotation: Subtype: Link Rect: 340, 569, 330, 587 Destination: External Annotation: Subtype: Link Rect: 366, 528, 356, 580 Destination: External Annotation: Subtype: Link Rect: 366, 582, 356, 599 Destination: External Annotation: Subtype: Link Rect: 366, 601, 356, 637 Destination: External Annotation: Subtype: Link Rect: 366, 638, 356, 660 Destination: External Annotation: Subtype: Link Rect: 382, 528, 373, 559 Destination: External Annotation: Subtype: Link Rect: 382, 560, 373, 578 Destination: External Annotation: Subtype: Link Rect: 394, 528, 385, 585 Destination: External Annotation: Subtype: Link Rect: 394, 586, 385, 604 Destination: External Annotation: Subtype: Link Rect: 394, 606, 385, 686 Destination: External Annotation: Subtype: Link Rect: 394, 687, 385, 705 Destination: External Annotation: Subtype: Link Rect: 410, 528, 401, 575 Destination: External Annotation: Subtype: Link Rect: 410, 577, 401, 595 Destination: External Annotation: Subtype: Link Rect: 410, 597, 401, 650 Destination: External Annotation: Subtype: Link Rect: 410, 651, 401, 669 Destination: External Annotation: Subtype: Link Rect: 422, 528, 413, 564 Destination: External Annotation: Subtype: Link Rect: 422, 566, 413, 584 Destination: External Annotation: Subtype: Link Rect: 422, 586, 413, 640 Destination: External Annotation: Subtype: Link Rect: 422, 642, 413, 659 Destination: External Annotation: Subtype: Link Rect: 442, 528, 432, 551 Destination: External Annotation: Subtype: Link Rect: 442, 553, 432, 571 Destination: External Annotation: Subtype: Link Rect: 442, 573, 432, 615 Destination: External Annotation: Subtype: Link Rect: 442, 617, 432, 635 Destination: External Annotation: Subtype: Link Rect: 480, 528, 471, 547 Destination: External Annotation: Subtype: Link Rect: 480, 549, 471, 567 Destination: External Annotation: Subtype: Link Rect: 480, 569, 471, 627 Destination: External Annotation: Subtype: Link Rect: 480, 628, 471, 646 Destination: External Annotation: Subtype: Link Rect: 506, 528, 497, 565 Destination: External Annotation: Subtype: Link Rect: 506, 567, 497, 585 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 6 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 278, 651, 63, 651 Destination: External Annotation: Subtype: Link Rect: 65, 640, 86, 651 Destination: External Annotation: Subtype: Link Rect: 86, 571, 128, 582 Destination: External Annotation: Subtype: Link Rect: 130, 571, 150, 582 Destination: External Annotation: Subtype: Link Rect: 84, 502, 147, 514 Destination: External Annotation: Subtype: Link Rect: 149, 502, 169, 514 Destination: External Annotation: Subtype: Link Rect: 122, 479, 164, 491 Destination: External Annotation: Subtype: Link Rect: 166, 479, 186, 491 Destination: External Annotation: Subtype: Link Rect: 138, 364, 220, 376 Destination: External Annotation: Subtype: Link Rect: 225, 364, 245, 376 Destination: External Annotation: Subtype: Link Rect: 249, 364, 289, 376 Destination: External Annotation: Subtype: Link Rect: 43, 353, 64, 364 Destination: External Annotation: Subtype: Link Rect: 66, 351, 100, 361 Destination: External Annotation: Subtype: Link Rect: 47, 296, 91, 307 Destination: External Annotation: Subtype: Link Rect: 94, 296, 119, 307 Destination: External Annotation: Subtype: Link Rect: 47, 261, 92, 273 Destination: External Annotation: Subtype: Link Rect: 95, 261, 115, 273 Destination: External Annotation: Subtype: Link Rect: 215, 250, 250, 261 Destination: External Annotation: Subtype: Link Rect: 252, 250, 273, 261 Destination: External Annotation: Subtype: Link Rect: 248, 204, 289, 215 Destination: External Annotation: Subtype: Link Rect: 43, 192, 64, 204 Destination: External Annotation: Subtype: Link Rect: 154, 147, 194, 158 Destination: External Annotation: Subtype: Link Rect: 196, 147, 216, 158 Destination: External Annotation: Subtype: Link Rect: 114, 87, 148, 98 Destination: External Annotation: Subtype: Link Rect: 522, 662, 325, 662 Destination: External Annotation: Subtype: Link Rect: 330, 651, 350, 662 Destination: External Annotation: Subtype: Link Rect: 354, 651, 375, 662 Destination: External Annotation: Subtype: Link Rect: 379, 651, 431, 662 Destination: External Annotation: Subtype: Link Rect: 435, 651, 455, 662 Destination: External Annotation: Subtype: Link Rect: 498, 594, 549, 605 Destination: External Annotation: Subtype: Link Rect: 304, 582, 324, 594 Destination: External Annotation: Subtype: Link Rect: 326, 582, 373, 594 Destination: External Annotation: Subtype: Link Rect: 375, 582, 396, 594 Destination: External Annotation: Subtype: Link Rect: 398, 582, 460, 594 Destination: External Annotation: Subtype: Link Rect: 462, 582, 482, 594 Destination: External Annotation: Subtype: Link Rect: 307, 525, 360, 536 Destination: External Annotation: Subtype: Link Rect: 365, 525, 385, 536 Destination: External Annotation: Subtype: Link Rect: 390, 525, 410, 536 Destination: External Annotation: Subtype: Link Rect: 415, 525, 435, 536 Destination: External Annotation: Subtype: Link Rect: 439, 525, 486, 536 Destination: External Annotation: Subtype: Link Rect: 491, 525, 511, 536 Destination: External Annotation: Subtype: Link Rect: 516, 525, 325, 525 Destination: External Annotation: Subtype: Link Rect: 329, 514, 350, 525 Destination: External Annotation: Subtype: Link Rect: 354, 514, 408, 525 Destination: External Annotation: Subtype: Link Rect: 412, 514, 432, 525 Destination: External Annotation: Subtype: Link Rect: 417, 410, 478, 422 Destination: External Annotation: Subtype: Link Rect: 484, 410, 504, 422 Destination: External Annotation: Subtype: Link Rect: 463, 342, 492, 353 Destination: External Annotation: Subtype: Link Rect: 495, 342, 515, 353 Destination: External Annotation: Subtype: Link Rect: 472, 319, 504, 330 Destination: External Annotation: Subtype: Link Rect: 507, 319, 527, 330 Destination: External Annotation: Subtype: Link Rect: 499, 261, 549, 273 Destination: External Annotation: Subtype: Link Rect: 304, 250, 324, 261 Destination: External Annotation: Subtype: Link Rect: 521, 239, 323, 239 Destination: External Annotation: Subtype: Link Rect: 326, 227, 346, 239 Destination: External Annotation: Subtype: Link Rect: 348, 227, 368, 239 Destination: External Annotation: Subtype: Link Rect: 398, 204, 461, 216 Destination: External Annotation: Subtype: Link Rect: 465, 204, 485, 216 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 7 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 139, 617, 200, 628 Destination: External Annotation: Subtype: Link Rect: 206, 617, 226, 628 Destination: External Annotation: Subtype: Link Rect: 66, 582, 125, 594 Destination: External Annotation: Subtype: Link Rect: 129, 582, 150, 594 Destination: External Annotation: Subtype: Link Rect: 154, 582, 203, 594 Destination: External Annotation: Subtype: Link Rect: 207, 582, 228, 594 Destination: External Annotation: Subtype: Link Rect: 232, 580, 266, 590 Destination: External Annotation: Subtype: Link Rect: 255, 525, 63, 525 Destination: External Annotation: Subtype: Link Rect: 65, 514, 86, 525 Destination: External Annotation: Subtype: Link Rect: 88, 514, 133, 525 Destination: External Annotation: Subtype: Link Rect: 135, 514, 155, 525 Destination: External Annotation: Subtype: Link Rect: 125, 468, 181, 479 Destination: External Annotation: Subtype: Link Rect: 184, 468, 204, 479 Destination: External Annotation: Subtype: Link Rect: 186, 456, 249, 468 Destination: External Annotation: Subtype: Link Rect: 252, 456, 272, 468 Destination: External Annotation: Subtype: Link Rect: 275, 456, 65, 456 Destination: External Annotation: Subtype: Link Rect: 69, 445, 90, 456 Destination: External Annotation: Subtype: Link Rect: 94, 445, 133, 456 Destination: External Annotation: Subtype: Link Rect: 137, 445, 157, 456 Destination: External Annotation: Subtype: Link Rect: 162, 445, 213, 456 Destination: External Annotation: Subtype: Link Rect: 217, 445, 237, 456 Destination: External Annotation: Subtype: Link Rect: 242, 445, 289, 456 Destination: External Annotation: Subtype: Link Rect: 43, 433, 64, 445 Destination: External Annotation: Subtype: Link Rect: 67, 433, 120, 445 Destination: External Annotation: Subtype: Link Rect: 123, 433, 144, 445 Destination: External Annotation: Subtype: Link Rect: 244, 410, 65, 410 Destination: External Annotation: Subtype: Link Rect: 69, 399, 89, 410 Destination: External Annotation: Subtype: Link Rect: 94, 399, 139, 410 Destination: External Annotation: Subtype: Link Rect: 143, 399, 163, 410 Destination: External Annotation: Subtype: Link Rect: 168, 399, 222, 410 Destination: External Annotation: Subtype: Link Rect: 226, 399, 246, 410 Destination: External Annotation: Subtype: Link Rect: 251, 399, 289, 410 Destination: External Annotation: Subtype: Link Rect: 43, 388, 64, 399 Destination: External Annotation: Subtype: Link Rect: 261, 376, 65, 376 Destination: External Annotation: Subtype: Link Rect: 69, 365, 89, 376 Destination: External Annotation: Subtype: Link Rect: 163, 342, 217, 353 Destination: External Annotation: Subtype: Link Rect: 220, 342, 240, 353 Destination: External Annotation: Subtype: Link Rect: 179, 307, 210, 319 Destination: External Annotation: Subtype: Link Rect: 213, 307, 233, 319 Destination: External Annotation: Subtype: Link Rect: 47, 239, 94, 250 Destination: External Annotation: Subtype: Link Rect: 97, 239, 117, 250 Destination: External Annotation: Subtype: Link Rect: 140, 216, 211, 227 Destination: External Annotation: Subtype: Link Rect: 215, 216, 235, 227 Destination: External Annotation: Subtype: Link Rect: 240, 216, 64, 216 Destination: External Annotation: Subtype: Link Rect: 68, 204, 88, 216 Destination: External Annotation: Subtype: Link Rect: 199, 181, 265, 193 Destination: External Annotation: Subtype: Link Rect: 267, 181, 287, 193 Destination: External Annotation: Subtype: Link Rect: 207, 170, 251, 181 Destination: External Annotation: Subtype: Link Rect: 254, 170, 278, 181 Destination: External Annotation: Subtype: Link Rect: 221, 158, 289, 170 Destination: External Annotation: Subtype: Link Rect: 43, 147, 64, 158 Destination: External Annotation: Subtype: Link Rect: 156, 135, 200, 147 Destination: External Annotation: Subtype: Link Rect: 203, 135, 227, 147 Destination: External Annotation: Subtype: Link Rect: 162, 87, 196, 98 Destination: External Annotation: Subtype: Link Rect: 168, 67, 219, 78 Destination: External Annotation: Subtype: Link Rect: 221, 67, 241, 78 Destination: External Annotation: Subtype: Link Rect: 463, 617, 523, 628 Destination: External Annotation: Subtype: Link Rect: 525, 617, 546, 628 Destination: External Annotation: Subtype: Link Rect: 521, 582, 344, 582 Destination: External Annotation: Subtype: Link Rect: 346, 571, 366, 582 Destination: External Annotation: Subtype: Link Rect: 369, 571, 472, 582 Destination: External Annotation: Subtype: Link Rect: 474, 571, 495, 582 Destination: External Annotation: Subtype: Link Rect: 479, 468, 520, 479 Destination: External Annotation: Subtype: Link Rect: 525, 468, 546, 479 Destination: External Annotation: Subtype: Link Rect: 509, 353, 549, 365 Destination: External Annotation: Subtype: Link Rect: 304, 342, 324, 353 Destination: External Annotation: Subtype: Link Rect: 354, 216, 392, 227 Destination: External Annotation: Subtype: Link Rect: 396, 216, 416, 227 Destination: External Annotation: Subtype: Link Rect: 354, 181, 407, 193 Destination: External Annotation: Subtype: Link Rect: 411, 181, 431, 193 Destination: External Annotation: Subtype: Link Rect: 531, 113, 326, 113 Destination: External Annotation: Subtype: Link Rect: 330, 101, 350, 113 Destination: External Annotation: Subtype: Link Rect: 397, 78, 465, 90 Destination: External Annotation: Subtype: Link Rect: 469, 78, 489, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 8 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 124, 708, 189, 720 Destination: External Annotation: Subtype: Link Rect: 193, 708, 213, 720 Destination: External Annotation: Subtype: Link Rect: 83, 605, 151, 617 Destination: External Annotation: Subtype: Link Rect: 154, 605, 174, 617 Destination: External Annotation: Subtype: Link Rect: 197, 525, 238, 536 Destination: External Annotation: Subtype: Link Rect: 241, 525, 261, 536 Destination: External Annotation: Subtype: Link Rect: 106, 491, 128, 502 Destination: External Annotation: Subtype: Link Rect: 132, 491, 152, 502 Destination: External Annotation: Subtype: Link Rect: 67, 456, 164, 468 Destination: External Annotation: Subtype: Link Rect: 168, 456, 188, 468 Destination: External Annotation: Subtype: Link Rect: 264, 433, 63, 433 Destination: External Annotation: Subtype: Link Rect: 66, 422, 86, 433 Destination: External Annotation: Subtype: Link Rect: 89, 422, 156, 433 Destination: External Annotation: Subtype: Link Rect: 158, 422, 178, 433 Destination: External Annotation: Subtype: Link Rect: 231, 353, 252, 364 Destination: External Annotation: Subtype: Link Rect: 255, 353, 275, 364 Destination: External Annotation: Subtype: Link Rect: 47, 307, 94, 318 Destination: External Annotation: Subtype: Link Rect: 98, 307, 118, 318 Destination: External Annotation: Subtype: Link Rect: 75, 272, 120, 284 Destination: External Annotation: Subtype: Link Rect: 123, 272, 143, 284 Destination: External Annotation: Subtype: Link Rect: 66, 204, 117, 215 Destination: External Annotation: Subtype: Link Rect: 120, 204, 141, 215 Destination: External Annotation: Subtype: Link Rect: 80, 192, 129, 204 Destination: External Annotation: Subtype: Link Rect: 131, 192, 151, 204 Destination: External Annotation: Subtype: Link Rect: 111, 146, 174, 158 Destination: External Annotation: Subtype: Link Rect: 178, 146, 198, 158 Destination: External Annotation: Subtype: Link Rect: 117, 123, 180, 135 Destination: External Annotation: Subtype: Link Rect: 183, 123, 203, 135 Destination: External Annotation: Subtype: Link Rect: 263, 112, 63, 112 Destination: External Annotation: Subtype: Link Rect: 65, 101, 85, 112 Destination: External Annotation: Subtype: Link Rect: 434, 708, 477, 720 Destination: External Annotation: Subtype: Link Rect: 480, 708, 500, 720 Destination: External Annotation: Subtype: Link Rect: 337, 685, 379, 697 Destination: External Annotation: Subtype: Link Rect: 381, 685, 401, 697 Destination: External Annotation: Subtype: Link Rect: 307, 628, 355, 640 Destination: External Annotation: Subtype: Link Rect: 357, 628, 377, 640 Destination: External Annotation: Subtype: Link Rect: 307, 605, 398, 617 Destination: External Annotation: Subtype: Link Rect: 401, 605, 421, 617 Destination: External Annotation: Subtype: Link Rect: 307, 536, 347, 548 Destination: External Annotation: Subtype: Link Rect: 351, 536, 371, 548 Destination: External Annotation: Subtype: Link Rect: 339, 479, 402, 491 Destination: External Annotation: Subtype: Link Rect: 406, 479, 426, 491 Destination: External Annotation: Subtype: Link Rect: 475, 445, 525, 456 Destination: External Annotation: Subtype: Link Rect: 527, 445, 548, 456 Destination: External Annotation: Subtype: Link Rect: 536, 376, 326, 376 Destination: External Annotation: Subtype: Link Rect: 330, 365, 350, 376 Destination: External Annotation: Subtype: Link Rect: 411, 365, 472, 376 Destination: External Annotation: Subtype: Link Rect: 476, 365, 497, 376 Destination: External Annotation: Subtype: Link Rect: 453, 353, 492, 365 Destination: External Annotation: Subtype: Link Rect: 495, 353, 515, 365 Destination: External Annotation: Subtype: Link Rect: 338, 342, 421, 353 Destination: External Annotation: Subtype: Link Rect: 425, 342, 445, 353 Destination: External Annotation: Subtype: Link Rect: 449, 342, 493, 353 Destination: External Annotation: Subtype: Link Rect: 497, 342, 517, 353 Destination: External Annotation: Subtype: Link Rect: 307, 330, 356, 342 Destination: External Annotation: Subtype: Link Rect: 360, 330, 380, 342 Destination: External Annotation: Subtype: Link Rect: 383, 330, 433, 342 Destination: External Annotation: Subtype: Link Rect: 436, 330, 456, 342 Destination: External Annotation: Subtype: Link Rect: 522, 330, 327, 330 Destination: External Annotation: Subtype: Link Rect: 333, 319, 354, 330 Destination: External Annotation: Subtype: Link Rect: 345, 284, 387, 296 Destination: External Annotation: Subtype: Link Rect: 389, 284, 409, 296 Destination: External Annotation: Subtype: Link Rect: 412, 284, 463, 296 Destination: External Annotation: Subtype: Link Rect: 465, 284, 486, 296 Destination: External Annotation: Subtype: Link Rect: 481, 239, 549, 250 Destination: External Annotation: Subtype: Link Rect: 304, 227, 324, 239 Destination: External Annotation: Subtype: Link Rect: 447, 204, 501, 216 Destination: External Annotation: Subtype: Link Rect: 506, 204, 527, 216 Destination: External Annotation: Subtype: Link Rect: 484, 193, 549, 204 Destination: External Annotation: Subtype: Link Rect: 304, 181, 324, 193 Destination: External Annotation: Subtype: Link Rect: 326, 181, 375, 193 Destination: External Annotation: Subtype: Link Rect: 377, 181, 398, 193 Destination: External Annotation: Subtype: Link Rect: 411, 158, 434, 170 Destination: External Annotation: Subtype: Link Rect: 437, 158, 457, 170 Destination: External Annotation: Subtype: Link Rect: 307, 101, 370, 113 Destination: External Annotation: Subtype: Link Rect: 373, 101, 393, 113 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 9 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 161, 595, 204, 607 Destination: External Annotation: Subtype: Link Rect: 207, 595, 227, 607 Destination: External Annotation: Subtype: Link Rect: 117, 561, 167, 572 Destination: External Annotation: Subtype: Link Rect: 169, 561, 189, 572 Destination: External Annotation: Subtype: Link Rect: 239, 538, 264, 549 Destination: External Annotation: Subtype: Link Rect: 268, 538, 289, 549 Destination: External Annotation: Subtype: Link Rect: 43, 526, 116, 538 Destination: External Annotation: Subtype: Link Rect: 119, 526, 139, 538 Destination: External Annotation: Subtype: Link Rect: 172, 515, 221, 526 Destination: External Annotation: Subtype: Link Rect: 224, 515, 244, 526 Destination: External Annotation: Subtype: Link Rect: 266, 469, 63, 469 Destination: External Annotation: Subtype: Link Rect: 65, 458, 86, 469 Destination: External Annotation: Subtype: Link Rect: 80, 376, 111, 385 Destination: External Annotation: Subtype: Link Rect: 436, 640, 492, 651 Destination: External Annotation: Subtype: Link Rect: 495, 640, 515, 651 Destination: External Annotation: Subtype: Link Rect: 307, 571, 356, 582 Destination: External Annotation: Subtype: Link Rect: 358, 571, 383, 582 Destination: External Annotation: Subtype: Link Rect: 383, 571, 390, 582 Destination: External Annotation: Subtype: Link Rect: 456, 410, 524, 422 Destination: External Annotation: Subtype: Link Rect: 527, 410, 548, 422 Destination: External Annotation: Subtype: Link Rect: 531, 342, 354, 342 Destination: External Annotation: Subtype: Link Rect: 356, 330, 377, 342 Destination: External Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 10 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 169, 671, 238, 678 Annotation: Subtype: Link Rect: 292, 630, 52, 651 Annotation: Subtype: Link Rect: 66, 603, 152, 612 Annotation: Subtype: Link Rect: 66, 566, 148, 574 Annotation: Subtype: Link Rect: 191, 538, 259, 546 Annotation: Subtype: Link Rect: 146, 461, 221, 470 Annotation: Subtype: Link Rect: 66, 424, 166, 432 Annotation: Subtype: Link Rect: 102, 387, 206, 394 Annotation: Subtype: Link Rect: 96, 347, 189, 357 Annotation: Subtype: Link Rect: 66, 319, 153, 328 Annotation: Subtype: Link Rect: 66, 281, 144, 290 Annotation: Subtype: Link Rect: 102, 254, 154, 262 Annotation: Subtype: Link Rect: 196, 235, 281, 243 Annotation: Subtype: Link Rect: 292, 185, 52, 206 Annotation: Subtype: Link Rect: 141, 160, 194, 167 Annotation: Subtype: Link Rect: 187, 130, 270, 139 Annotation: Subtype: Link Rect: 109, 103, 184, 110 Annotation: Subtype: Link Rect: 163, 73, 252, 82 Annotation: Subtype: Link Rect: 327, 671, 405, 678 Annotation: Subtype: Link Rect: 373, 641, 431, 650 Annotation: Subtype: Link Rect: 327, 603, 406, 612 Annotation: Subtype: Link Rect: 327, 565, 409, 574 Annotation: Subtype: Link Rect: 327, 518, 401, 527 Annotation: Subtype: Link Rect: 327, 489, 416, 499 Annotation: Subtype: Link Rect: 363, 451, 469, 461 Annotation: Subtype: Link Rect: 327, 432, 406, 442 Annotation: Subtype: Link Rect: 423, 414, 513, 423 Annotation: Subtype: Link Rect: 383, 385, 462, 394 Annotation: Subtype: Link Rect: 327, 349, 423, 357 Annotation: Subtype: Link Rect: 409, 311, 511, 318 Annotation: Subtype: Link Rect: 327, 273, 392, 281 Annotation: Subtype: Link Rect: 327, 235, 430, 243 Annotation: Subtype: Link Rect: 327, 216, 403, 224 Annotation: Subtype: Link Rect: 327, 179, 430, 186 Annotation: Subtype: Link Rect: 366, 141, 456, 148 Annotation: Subtype: Link Rect: 404, 112, 471, 120 Annotation: Subtype: Link Rect: 327, 73, 406, 82 Annotation: Subtype: Link Rect: 43, 28, 175, 37 Annotation: Subtype: Link Rect: 179, 28, 239, 36 Annotation: Subtype: Link Rect: 438, 28, 551, 37 Page: Label: 11 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 66, 687, 158, 697 Annotation: Subtype: Link Rect: 66, 650, 163, 659 Annotation: Subtype: Link Rect: 109, 623, 175, 630 Annotation: Subtype: Link Rect: 150, 594, 231, 602 Annotation: Subtype: Link Rect: 292, 546, 52, 565 Annotation: Subtype: Link Rect: 137, 481, 189, 488 Annotation: Subtype: Link Rect: 95, 432, 180, 441 Annotation: Subtype: Link Rect: 186, 404, 266, 413 Annotation: Subtype: Link Rect: 110, 375, 189, 384 Annotation: Subtype: Link Rect: 176, 358, 252, 366 Annotation: Subtype: Link Rect: 66, 328, 159, 337 Annotation: Subtype: Link Rect: 102, 292, 206, 299 Annotation: Subtype: Link Rect: 66, 254, 120, 261 Annotation: Subtype: Link Rect: 66, 225, 159, 233 Annotation: Subtype: Link Rect: 66, 186, 141, 195 Annotation: Subtype: Link Rect: 102, 150, 206, 157 Annotation: Subtype: Link Rect: 88, 110, 167, 119 Annotation: Subtype: Link Rect: 66, 74, 170, 81 Annotation: Subtype: Link Rect: 327, 678, 406, 687 Annotation: Subtype: Link Rect: 462, 650, 544, 659 Annotation: Subtype: Link Rect: 327, 613, 402, 621 Annotation: Subtype: Link Rect: 464, 583, 525, 592 Annotation: Subtype: Link Rect: 327, 547, 403, 554 Annotation: Subtype: Link Rect: 379, 498, 467, 507 Annotation: Subtype: Link Rect: 452, 452, 510, 460 Annotation: Subtype: Link Rect: 552, 403, 313, 423 Annotation: Subtype: Link Rect: 327, 377, 400, 384 Annotation: Subtype: Link Rect: 327, 337, 410, 347 Annotation: Subtype: Link Rect: 422, 311, 487, 318 Annotation: Subtype: Link Rect: 454, 292, 507, 299 Annotation: Subtype: Link Rect: 327, 262, 460, 271 Annotation: Subtype: Link Rect: 327, 224, 416, 233 Annotation: Subtype: Link Rect: 327, 197, 444, 204 Annotation: Subtype: Link Rect: 370, 159, 455, 166 Annotation: Subtype: Link Rect: 399, 131, 464, 138 Annotation: Subtype: Link Rect: 370, 101, 449, 110 Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 12 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 66, 699, 170, 706 Annotation: Subtype: Link Rect: 66, 670, 147, 678 Annotation: Subtype: Link Rect: 199, 650, 289, 659 Annotation: Subtype: Link Rect: 66, 612, 146, 621 Annotation: Subtype: Link Rect: 125, 594, 177, 602 Annotation: Subtype: Link Rect: 201, 565, 280, 573 Annotation: Subtype: Link Rect: 66, 538, 131, 545 Annotation: Subtype: Link Rect: 66, 498, 159, 508 Annotation: Subtype: Link Rect: 66, 471, 148, 479 Annotation: Subtype: Link Rect: 66, 434, 127, 441 Annotation: Subtype: Link Rect: 292, 394, 52, 414 Annotation: Subtype: Link Rect: 134, 347, 231, 356 Annotation: Subtype: Link Rect: 161, 318, 250, 328 Annotation: Subtype: Link Rect: 185, 290, 235, 299 Annotation: Subtype: Link Rect: 292, 251, 52, 272 Annotation: Subtype: Link Rect: 66, 214, 127, 223 Annotation: Subtype: Link Rect: 66, 186, 145, 195 Annotation: Subtype: Link Rect: 66, 150, 153, 157 Annotation: Subtype: Link Rect: 66, 112, 152, 119 Annotation: Subtype: Link Rect: 66, 72, 148, 82 Annotation: Subtype: Link Rect: 327, 687, 431, 697 Annotation: Subtype: Link Rect: 487, 670, 551, 678 Annotation: Subtype: Link Rect: 435, 651, 529, 659 Annotation: Subtype: Link Rect: 481, 623, 551, 630 Annotation: Subtype: Link Rect: 385, 604, 471, 611 Annotation: Subtype: Link Rect: 425, 576, 491, 583 Annotation: Subtype: Link Rect: 327, 538, 398, 545 Annotation: Subtype: Link Rect: 327, 509, 426, 517 Annotation: Subtype: Link Rect: 327, 481, 427, 488 Annotation: Subtype: Link Rect: 327, 441, 420, 451 Annotation: Subtype: Link Rect: 387, 424, 448, 431 Annotation: Subtype: Link Rect: 445, 394, 524, 403 Annotation: Subtype: Link Rect: 552, 355, 313, 376 Annotation: Subtype: Link Rect: 327, 329, 444, 337 Annotation: Subtype: Link Rect: 327, 282, 432, 289 Annotation: Subtype: Link Rect: 406, 243, 485, 252 Annotation: Subtype: Link Rect: 327, 178, 429, 185 Annotation: Subtype: Link Rect: 388, 121, 462, 129 Annotation: Subtype: Link Rect: 419, 102, 518, 110 Annotation: Subtype: Link Rect: 366, 72, 431, 82 Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 130, 680, 241, 687 Annotation: Subtype: Link Rect: 66, 642, 125, 649 Annotation: Subtype: Link Rect: 102, 622, 201, 631 Annotation: Subtype: Link Rect: 194, 593, 266, 602 Annotation: Subtype: Link Rect: 238, 538, 291, 545 Annotation: Subtype: Link Rect: 66, 508, 138, 517 Annotation: Subtype: Link Rect: 95, 481, 160, 488 Annotation: Subtype: Link 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Subtype: Link Rect: 370, 375, 449, 384 Annotation: Subtype: Link Rect: 419, 347, 502, 356 Annotation: Subtype: Link Rect: 327, 318, 399, 327 Annotation: Subtype: Link Rect: 353, 290, 412, 299 Annotation: Subtype: Link Rect: 440, 262, 510, 271 Annotation: Subtype: Link Rect: 327, 224, 433, 233 Annotation: Subtype: Link Rect: 463, 197, 542, 204 Annotation: Subtype: Link Rect: 405, 102, 431, 109 Annotation: Subtype: Link Rect: 431, 102, 463, 109 Annotation: Subtype: Link Rect: 463, 102, 499, 110 Annotation: Subtype: Link Rect: 499, 102, 522, 109 Annotation: Subtype: Link Rect: 522, 101, 549, 110 Annotation: Subtype: Link Rect: 43, 29, 175, 38 Annotation: Subtype: Link Rect: 179, 29, 239, 37 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Checksum: 6a30b7fc Type: CRC32 Checksum: f3a1d0746e2e54fc147b995ffcee6a97 Type: MD5 Checksum: ec2894d548a6a20f20743f5b6755864586a12816 Type: SHA-1