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1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7c53a9eb Children: Item: Title: 1. Introduction: Down syndrome at high risk for Alzheimer's disease Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed17bee Item: Title: 2. Cerebrospinal fluid biomarkers for AD in the general population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2a33fae0 Item: Title: 3. Few CSF studies in DS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@707f7052 Item: Title: 4. Need for CSF analyses in DS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11028347 Item: Title: 5. Future avenues Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@14899482 Item: Title: 6. Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Info: Title: Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome Author: Alain D. Dekker Subject: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 8 (2017) 1-10. doi:10.1016/j.dadm.2017.02.006 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) ID: 0xfb3b4b1da1b08414560a4e4263dead9a, 0x4c7de6329f9d0f46a1652c4cfa30ab0f Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 120 ImageHeight: 120 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 251 ImageHeight: 276 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: Separation Image: NisoImageMetadata: CompressionScheme: JPEG ImageWidth: 1699 ImageHeight: 1396 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: GPJNPB+AdvPSSym FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: GPJNPB+AdvPSSym Flags: Symbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: GPJNNM+AdvPSA88A FontSubset: true FirstChar: 37 LastChar: 245 FontDescriptor: FontName: GPJNNM+AdvPSA88A Flags: Serif, Nonsymbolic FontBBox: -166, -208, 1000, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: GPJNPC+AdvPS586B FontSubset: true FirstChar: 44 LastChar: 54 FontDescriptor: FontName: GPJNPC+AdvPS586B Flags: Nonsymbolic FontBBox: -20, -229, 1010, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GPJNNN+AdvPSA88C FontSubset: true FirstChar: 38 LastChar: 146 FontDescriptor: FontName: GPJNNN+AdvPSA88C Flags: Serif, Nonsymbolic FontBBox: -166, -208, 1010, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GPJNNO+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 160 FontDescriptor: FontName: GPJNNO+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GPJNNP+AdvPSA88B FontSubset: true FirstChar: 31 LastChar: 146 FontDescriptor: FontName: GPJNNP+AdvPSA88B Flags: Serif, Nonsymbolic FontBBox: -166, -208, 1000, 781 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: GPKAMA+AdvP4C4E74 FontSubset: true FirstChar: 106 LastChar: 123 FontDescriptor: FontName: GPKAMA+AdvP4C4E74 Flags: Nonsymbolic FontBBox: -20, -958, 1114, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GPJNPA+AdvPS3F4C13 FontSubset: true FirstChar: 97 LastChar: 103 FontDescriptor: FontName: GPJNPA+AdvPS3F4C13 Flags: Nonsymbolic FontBBox: 0, -291, 875, 697 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.dadm.2017.02.006 Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome Alain D. Dekker Juan Fortea Rafael Blesa Peter P. De Deyn Alzheimer's disease Biomarkers Cerebrospinal fluid Dementia Down syndrome Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 8 (2017) 1-10. doi:10.1016/j.dadm.2017.02.006 Elsevier Inc. journal Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring © 2017 The Authors. 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694 Annotation: Subtype: Link Rect: 54, 676, 276, 684 Annotation: Subtype: Link Rect: 54, 666, 276, 674 Annotation: Subtype: Link Rect: 54, 656, 96, 664 Annotation: Subtype: Link Rect: 54, 646, 276, 654 Annotation: Subtype: Link Rect: 54, 636, 276, 644 Annotation: Subtype: Link Rect: 54, 626, 276, 634 Annotation: Subtype: Link Rect: 54, 616, 276, 624 Annotation: Subtype: Link Rect: 54, 606, 92, 614 Annotation: Subtype: Link Rect: 54, 596, 276, 604 Annotation: Subtype: Link Rect: 54, 586, 276, 594 Annotation: Subtype: Link Rect: 317, 696, 539, 704 Annotation: Subtype: Link Rect: 317, 686, 491, 694 Annotation: Subtype: Link Rect: 317, 676, 539, 684 Annotation: Subtype: Link Rect: 317, 666, 539, 674 Annotation: Subtype: Link Rect: 317, 656, 418, 664 Annotation: Subtype: Link Rect: 317, 646, 539, 654 Annotation: Subtype: Link Rect: 317, 636, 539, 644 Annotation: Subtype: Link Rect: 317, 626, 392, 634 Annotation: Subtype: Link Rect: 317, 616, 539, 624 Annotation: Subtype: Link Rect: 317, 606, 539, 614 Annotation: Subtype: Link Rect: 317, 596, 539, 604 Annotation: Subtype: Link Rect: 317, 586, 382, 594 Checksum: 509b46d6 Type: CRC32 Checksum: 3c6adcdbc66ae07fe669646e75abc33c Type: MD5 Checksum: 9fc4e9cb6bde38d8f888e85e422ac7465a2893a7 Type: SHA-1