fd6572cab0529acb419c80147659194d pmc_28861074.pdf 41ba510c921f376bd3af51ff8256e4365a8318a2 pmc_28861074.pdf Title: The Probiotic Combination of Bifidobacterium longum subsp. infantis CECT 7210 and Bifidobacterium animalis subsp. lactis BPL6 Reduces Pathogen Loads and Improves Gut Health of Weaned Piglets Orally Challenged with Salmonella Typhimurium Subject: Probiotics have been demonstrated to be useful to enhance gut health and prevent gastrointestinal infections in humans. Keywords: multi-strain probiotic, Bifidobacterium sp., pig model, Salmonella Typhimurium, microbiota, diarrhea, infant model Author: Susana M. Martín-Orúe Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sat Aug 12 12:13:58 2017 CEST ModDate: Sat Aug 12 13:27:51 2017 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 878294 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XCOHVY+MinionPro-Regular Type 1 Custom yes yes no 41 0 JGWCAD+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 42 0 PGKSCI+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 43 0 XFIUNY+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 44 0 GPBKSX+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 45 0 INTWGQ+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 47 0 JDKMNY+MTSYN Type 1 Builtin yes yes no 48 0 SQRAFJ+RBLMI Type 1 Builtin yes yes no 49 0 HYGMSX+MinionPro-It Type 1 Custom yes yes no 108 0 NFWZSN+MinionPro-Bold Type 1 Custom yes yes no 154 0 CFYSLP+HelveticaNeueLTStd-Roman Type 1 Custom yes yes no 156 0 CFTLTF+MTGU Type 1 Builtin yes yes no 187 0 WXGRYX+MTGUB Type 1 Builtin yes yes no 307 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2019-02-14 17:54:14 CET RepresentationInformation: pmc_28861074.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2018-02-08 07:50:28 CET Size: 878294 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 699 FreeObjects: 3 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: The Probiotic Combination of Bifidobacterium longum subsp. infantis CECT 7210 and Bifidobacterium animalis subsp. lactis BPL6 Reduces Pathogen Loads and Improves Gut Health of Weaned Piglets Orally Challenged with Salmonella Typhimurium Children: Item: Title: Introduction Item: Title: Materials And Methods Children: Item: Title: Animals and Housing Item: Title: Experimental Products and Diets Item: Title: Bacterial Strain Item: Title: Experimental Procedure Item: Title: Analytical Procedures Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: Animal Performance Item: Title: Clinical Signs Item: Title: Salmonella Analysis Item: Title: Changes in Fermentative Activity Item: Title: Immune Response Item: Title: Intestinal Morphology Item: Title: Discussion Item: Title: Conclusion Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: References Info: Title: The Probiotic Combination of Bifidobacterium longum subsp. infantis CECT 7210 and Bifidobacterium animalis subsp. lactis BPL6 Reduces Pathogen Loads and Improves Gut Health of Weaned Piglets Orally Challenged with Salmonella Typhimurium Author: Susana M. Martín-Orúe Subject: Probiotics have been demonstrated to be useful to enhance gut health and prevent gastrointestinal infections in humans. Keywords: multi-strain probiotic, Bifidobacterium sp., pig model, Salmonella Typhimurium, microbiota, diarrhea, infant model Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sat Aug 12 12:43:58 CEST 2017 ModDate: Sat Aug 12 13:57:51 CEST 2017 ID: 0xf769d1589cf3cee854d8a717ba82104d, 0xa0caf20c492c754d9311b60abc6d381d Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: XCOHVY+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: XCOHVY+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JGWCAD+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: JGWCAD+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: PGKSCI+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: PGKSCI+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XFIUNY+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 2 LastChar: 121 FontDescriptor: FontName: XFIUNY+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: HYGMSX+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: HYGMSX+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GPBKSX+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: GPBKSX+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: INTWGQ+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 250 FontDescriptor: FontName: INTWGQ+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JDKMNY+MTSYN FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: JDKMNY+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: SQRAFJ+RBLMI FontSubset: true FirstChar: 59 LastChar: 62 FontDescriptor: FontName: SQRAFJ+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: WXGRYX+MTGUB FontSubset: true FirstChar: 97 LastChar: 97 FontDescriptor: FontName: WXGRYX+MTGUB Flags: Symbolic FontBBox: 0, -205, 879, 699 FontFile: true Font: BaseFont: NFWZSN+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: NFWZSN+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CFTLTF+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: CFTLTF+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: CFYSLP+HelveticaNeueLTStd-Roman FontSubset: true FirstChar: 65 LastChar: 103 FontDescriptor: FontName: CFYSLP+HelveticaNeueLTStd-Roman Flags: Symbolic FontBBox: -166, -214, 1076, 952 FontFile: true EncodingDictionary: Differences: true XMP: application/pdf Susana M. Martín-Orúe Probiotics have been demonstrated to be useful to enhance gut health and prevent gastrointestinal infections in humans. The Probiotic Combination of Bifidobacterium longum subsp. infantis CECT 7210 and Bifidobacterium animalis subsp. lactis BPL6 Reduces Pathogen Loads and Improves Gut Health of Weaned Piglets Orally Challenged with Salmonella Typhimurium multi-strain probiotic Bifidobacterium sp. pig model Salmonella Typhimurium microbiota diarrhea infant model 2017-08-12T15:43:58+05:30 LaTeX with hyperref package 2017-08-12T16:57:51+05:30 2017-08-12T16:57:51+05:30 multi-strain probiotic, Bifidobacterium sp., pig model, Salmonella Typhimurium, microbiota, diarrhea, infant model pdfTeX-1.40.15 False This is MiKTeX-pdfTeX 2.9.5496 (1.40.15) uuid:706593f4-541b-4f19-a2b1-b9ef56855e92 uuid:03d4d121-6ca4-4078-b470-d21f60ad1e58 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 43, 718, 160, 754 Annotation: Subtype: Link Rect: 474, 736, 551, 745 Annotation: Subtype: Link Rect: 467, 727, 551, 737 Annotation: Subtype: Link Rect: 453, 718, 551, 729 Annotation: Subtype: Link Rect: 86, 462, 160, 472 Annotation: Subtype: Link Rect: 75, 67, 160, 74 Annotation: Subtype: Link Rect: 521, 677, 551, 707 Annotation: Subtype: Link Rect: 176, 469, 551, 651 Annotation: Subtype: Link Rect: 176, 448, 250, 459 Annotation: Subtype: Link Rect: 256, 448, 332, 459 Annotation: Subtype: Link Rect: 411, 448, 513, 459 Annotation: Subtype: Link Rect: 176, 437, 274, 449 Annotation: Subtype: Link Rect: 296, 437, 395, 449 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 268, 576, 290, 588 ActionDest: 464 Annotation: Subtype: Link Rect: 43, 565, 64, 576 ActionDest: 464 Annotation: Subtype: Link Rect: 264, 565, 292, 576 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 554, 66, 565 ActionDest: 526 Annotation: Subtype: Link Rect: 72, 554, 92, 565 ActionDest: 526 Annotation: Subtype: Link Rect: 91, 519, 146, 530 ActionDest: 526 Annotation: Subtype: Link Rect: 151, 519, 171, 530 ActionDest: 526 Annotation: Subtype: Link Rect: 177, 519, 290, 530 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 508, 64, 519 ActionDest: 526 Annotation: Subtype: Link Rect: 145, 485, 214, 496 ActionDest: 526 Annotation: Subtype: Link Rect: 221, 485, 241, 496 ActionDest: 526 Annotation: Subtype: Link Rect: 267, 450, 290, 462 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 440, 64, 450 ActionDest: 526 Annotation: Subtype: Link Rect: 156, 394, 172, 404 ActionDest: 526 Annotation: Subtype: Link Rect: 178, 394, 198, 404 ActionDest: 526 Annotation: Subtype: Link Rect: 204, 394, 261, 404 ActionDest: 526 Annotation: Subtype: Link Rect: 267, 394, 287, 404 ActionDest: 526 Annotation: Subtype: Link Rect: 274, 347, 292, 359 ActionDest: 464 Annotation: Subtype: Link Rect: 43, 337, 88, 347 ActionDest: 464 Annotation: Subtype: Link Rect: 92, 337, 112, 347 ActionDest: 464 Annotation: Subtype: Link Rect: 117, 337, 174, 347 ActionDest: 464 Annotation: Subtype: Link Rect: 179, 337, 203, 347 ActionDest: 464 Annotation: Subtype: Link Rect: 208, 337, 244, 347 ActionDest: 526 Annotation: Subtype: Link Rect: 249, 337, 269, 347 ActionDest: 526 Annotation: Subtype: Link Rect: 164, 302, 212, 313 ActionDest: 526 Annotation: Subtype: Link Rect: 215, 302, 236, 313 ActionDest: 526 Annotation: Subtype: Link Rect: 239, 302, 290, 313 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 290, 64, 301 ActionDest: 526 Annotation: Subtype: Link Rect: 205, 290, 245, 301 ActionDest: 526 Annotation: Subtype: Link Rect: 248, 290, 268, 301 ActionDest: 526 Annotation: Subtype: Link Rect: 272, 290, 292, 301 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 279, 66, 290 ActionDest: 526 Annotation: Subtype: Link Rect: 71, 279, 91, 290 ActionDest: 526 Annotation: Subtype: Link Rect: 96, 279, 156, 290 ActionDest: 548 Annotation: Subtype: Link Rect: 161, 279, 181, 290 ActionDest: 548 Annotation: Subtype: Link Rect: 66, 221, 138, 233 ActionDest: 464 Annotation: Subtype: Link Rect: 142, 221, 162, 233 ActionDest: 464 Annotation: Subtype: Link Rect: 259, 211, 292, 221 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 199, 93, 210 ActionDest: 526 Annotation: Subtype: Link Rect: 95, 199, 116, 210 ActionDest: 526 Annotation: Subtype: Link Rect: 91, 141, 168, 152 ActionDest: 526 Annotation: Subtype: Link Rect: 174, 141, 194, 152 ActionDest: 526 Annotation: Subtype: Link Rect: 200, 141, 259, 152 ActionDest: 464 Annotation: Subtype: Link Rect: 265, 141, 290, 152 ActionDest: 464 Annotation: Subtype: Link Rect: 43, 130, 109, 141 ActionDest: 464 Annotation: Subtype: Link Rect: 115, 130, 135, 141 ActionDest: 464 Annotation: Subtype: Link Rect: 512, 464, 551, 475 ActionDest: 526 Annotation: Subtype: Link Rect: 302, 453, 353, 463 ActionDest: 526 Annotation: Subtype: Link Rect: 355, 453, 375, 463 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 196, 463, 227, 474 ActionDest: 148 Annotation: Subtype: Link Rect: 47, 440, 68, 451 ActionDest: 526 Annotation: Subtype: Link Rect: 70, 440, 91, 451 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 92, 213, 173, 225 ActionDest: 464 Annotation: Subtype: Link Rect: 176, 213, 196, 225 ActionDest: 464 Annotation: Subtype: Link Rect: 253, 202, 292, 213 ActionDest: 548 Annotation: Subtype: Link Rect: 43, 191, 63, 202 ActionDest: 548 Annotation: Subtype: Link Rect: 67, 191, 87, 202 ActionDest: 548 Annotation: Subtype: Link Rect: 351, 408, 403, 419 ActionDest: 526 Annotation: Subtype: Link Rect: 407, 408, 427, 419 ActionDest: 526 Annotation: Subtype: Link Rect: 518, 408, 551, 419 ActionDest: 464 Annotation: Subtype: Link Rect: 302, 396, 323, 408 ActionDest: 464 Annotation: Subtype: Link Rect: 327, 396, 347, 408 ActionDest: 464 Annotation: Subtype: Link Rect: 407, 339, 473, 350 ActionDest: 526 Annotation: Subtype: Link Rect: 477, 339, 497, 350 ActionDest: 526 Annotation: Subtype: Link Rect: 302, 328, 351, 339 ActionDest: 526 Annotation: Subtype: Link Rect: 355, 328, 375, 339 ActionDest: 526 Annotation: Subtype: Link Rect: 405, 157, 463, 168 ActionDest: 526 Annotation: Subtype: Link Rect: 466, 157, 487, 168 ActionDest: 526 Annotation: Subtype: Link Rect: 430, 76, 474, 88 ActionDest: 526 Annotation: Subtype: Link Rect: 479, 76, 500, 88 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 47, 603, 120, 614 ActionDest: 526 Annotation: Subtype: Link Rect: 125, 603, 145, 614 ActionDest: 526 Annotation: Subtype: Link Rect: 75, 276, 160, 288 ActionDest: 548 Annotation: Subtype: Link Rect: 163, 276, 183, 288 ActionDest: 548 Annotation: Subtype: Link Rect: 370, 531, 402, 542 ActionDest: 214 Annotation: Subtype: Link Rect: 312, 451, 347, 462 ActionDest: 243 Annotation: Subtype: Link Rect: 302, 345, 340, 356 ActionDest: 243 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 43, 156, 79, 167 ActionDest: 243 Annotation: Subtype: Link Rect: 314, 456, 354, 467 ActionDest: 272 Annotation: Subtype: Link Rect: 302, 316, 336, 328 ActionDest: 272 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 302, 120, 335, 131 ActionDest: 297 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 56, 632, 88, 643 ActionDest: 297 Annotation: Subtype: Link Rect: 517, 528, 551, 540 ActionDest: 548 Annotation: Subtype: Link Rect: 302, 517, 353, 528 ActionDest: 548 Annotation: Subtype: Link Rect: 356, 517, 377, 528 ActionDest: 548 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 244, 568, 290, 580 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 557, 64, 568 ActionDest: 526 Annotation: Subtype: Link Rect: 66, 557, 127, 568 ActionDest: 464 Annotation: Subtype: Link Rect: 130, 557, 150, 568 ActionDest: 464 Annotation: Subtype: Link Rect: 131, 511, 184, 522 ActionDest: 526 Annotation: Subtype: Link Rect: 188, 511, 208, 522 ActionDest: 526 Annotation: Subtype: Link Rect: 179, 385, 235, 396 ActionDest: 464 Annotation: Subtype: Link Rect: 239, 385, 259, 396 ActionDest: 464 Annotation: Subtype: Link Rect: 263, 385, 292, 396 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 374, 65, 385 ActionDest: 526 Annotation: Subtype: Link Rect: 69, 374, 90, 385 ActionDest: 526 Annotation: Subtype: Link Rect: 74, 362, 110, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 111, 362, 132, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 134, 362, 184, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 186, 362, 206, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 208, 362, 265, 373 ActionDest: 464 Annotation: Subtype: Link Rect: 267, 362, 287, 373 ActionDest: 464 Annotation: Subtype: Link Rect: 160, 351, 216, 362 ActionDest: 526 Annotation: Subtype: Link Rect: 220, 351, 240, 362 ActionDest: 526 Annotation: Subtype: Link Rect: 234, 339, 292, 351 ActionDest: 464 Annotation: Subtype: Link Rect: 43, 328, 64, 339 ActionDest: 464 Annotation: Subtype: Link Rect: 66, 328, 87, 339 ActionDest: 464 Annotation: Subtype: Link Rect: 260, 316, 292, 328 ActionDest: 526 Annotation: Subtype: Link Rect: 43, 306, 66, 316 ActionDest: 526 Annotation: Subtype: Link Rect: 71, 306, 91, 316 ActionDest: 526 Annotation: Subtype: Link Rect: 97, 306, 147, 316 ActionDest: 526 Annotation: Subtype: Link Rect: 152, 306, 172, 316 ActionDest: 526 Annotation: Subtype: Link Rect: 157, 248, 228, 259 ActionDest: 464 Annotation: Subtype: Link Rect: 232, 248, 252, 259 ActionDest: 464 Annotation: Subtype: Link Rect: 207, 213, 262, 225 ActionDest: 464 Annotation: Subtype: Link Rect: 267, 213, 287, 225 ActionDest: 464 Annotation: Subtype: Link Rect: 101, 190, 182, 202 ActionDest: 526 Annotation: Subtype: Link Rect: 185, 190, 205, 202 ActionDest: 526 Annotation: Subtype: Link Rect: 524, 706, 551, 717 ActionDest: 548 Annotation: Subtype: Link Rect: 302, 694, 323, 706 ActionDest: 548 Annotation: Subtype: Link Rect: 327, 694, 347, 706 ActionDest: 548 Annotation: Subtype: Link Rect: 340, 500, 440, 511 ActionDest: 464 Annotation: Subtype: Link Rect: 444, 500, 465, 511 ActionDest: 464 Annotation: Subtype: Link Rect: 395, 397, 493, 408 ActionDest: 464 Annotation: Subtype: Link Rect: 496, 397, 516, 408 ActionDest: 464 Annotation: Subtype: Link Rect: 519, 397, 551, 408 ActionDest: 526 Annotation: Subtype: Link Rect: 302, 386, 358, 396 ActionDest: 526 Annotation: Subtype: Link Rect: 362, 386, 383, 396 ActionDest: 526 Annotation: Subtype: Link Rect: 405, 374, 506, 385 ActionDest: 464 Annotation: Subtype: Link Rect: 510, 374, 530, 385 ActionDest: 464 Annotation: Subtype: Link Rect: 534, 374, 551, 385 ActionDest: 526 Annotation: Subtype: Link Rect: 302, 362, 375, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 379, 362, 399, 373 ActionDest: 526 Annotation: Subtype: Link Rect: 378, 306, 461, 316 ActionDest: 464 Annotation: Subtype: Link Rect: 464, 306, 484, 316 ActionDest: 464 Annotation: Subtype: Link Rect: 305, 133, 351, 144 ActionDest: 548 Annotation: Subtype: Link Rect: 353, 133, 374, 144 ActionDest: 548 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 129, 706, 183, 717 ActionDest: 464 Annotation: Subtype: Link Rect: 187, 706, 207, 717 ActionDest: 464 Annotation: Subtype: Link Rect: 211, 706, 265, 717 ActionDest: 464 Annotation: Subtype: Link Rect: 269, 706, 289, 717 ActionDest: 464 Annotation: Subtype: Link Rect: 172, 397, 228, 408 ActionDest: 526 Annotation: Subtype: Link Rect: 232, 397, 252, 408 ActionDest: 526 Annotation: Subtype: Link Rect: 47, 340, 73, 351 ActionDest: 526 Annotation: Subtype: Link Rect: 76, 340, 97, 351 ActionDest: 526 Annotation: Subtype: Link Rect: 100, 340, 153, 351 ActionDest: 464 Annotation: Subtype: Link Rect: 156, 340, 177, 351 ActionDest: 464 Annotation: Subtype: Link Rect: 180, 340, 233, 351 ActionDest: 464 Annotation: Subtype: Link Rect: 236, 340, 261, 351 ActionDest: 464 Annotation: Subtype: Link Rect: 202, 316, 258, 328 ActionDest: 464 Annotation: Subtype: Link Rect: 262, 316, 287, 328 ActionDest: 464 Annotation: Subtype: Link Rect: 47, 282, 99, 293 ActionDest: 464 Annotation: Subtype: Link Rect: 101, 282, 121, 293 ActionDest: 464 Annotation: Subtype: Link Rect: 376, 671, 452, 683 ActionDest: 526 Annotation: Subtype: Link Rect: 455, 671, 475, 683 ActionDest: 526 Annotation: Subtype: Link Rect: 478, 671, 522, 683 ActionDest: 548 Annotation: Subtype: Link Rect: 525, 671, 545, 683 ActionDest: 548 Annotation: Subtype: Link Rect: 473, 649, 549, 661 ActionDest: 526 Annotation: Subtype: Link Rect: 302, 638, 322, 648 ActionDest: 526 Annotation: Subtype: Link Rect: 328, 638, 385, 648 ActionDest: 526 Annotation: Subtype: Link Rect: 391, 638, 411, 648 ActionDest: 526 Annotation: Subtype: Link Rect: 441, 638, 520, 648 ActionDest: 526 Annotation: Subtype: Link Rect: 527, 638, 548, 648 ActionDest: 526 Annotation: Subtype: Link Rect: 432, 339, 494, 351 ActionDest: 526 Annotation: Subtype: Link Rect: 497, 339, 517, 351 ActionDest: 526 Annotation: Subtype: Link Rect: 389, 305, 441, 316 ActionDest: 464 Annotation: Subtype: Link Rect: 443, 305, 464, 316 ActionDest: 464 Annotation: Subtype: Link Rect: 387, 236, 460, 247 ActionDest: 464 Annotation: Subtype: Link Rect: 465, 236, 485, 247 ActionDest: 464 Annotation: Subtype: Link Rect: 374, 156, 437, 167 ActionDest: 526 Annotation: Subtype: Link Rect: 443, 156, 463, 167 ActionDest: 526 Annotation: Subtype: Link Rect: 469, 156, 520, 167 ActionDest: 464 Annotation: Subtype: Link Rect: 525, 156, 545, 167 ActionDest: 464 Annotation: Subtype: Link Rect: 511, 133, 551, 144 ActionDest: 464 Annotation: Subtype: Link Rect: 302, 122, 325, 133 ActionDest: 464 Annotation: Subtype: Link Rect: 330, 122, 350, 133 ActionDest: 464 Annotation: Subtype: Link Rect: 398, 87, 467, 99 ActionDest: 464 Annotation: Subtype: Link Rect: 470, 87, 490, 99 ActionDest: 464 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 126, 386, 227, 396 Annotation: Subtype: Link Rect: 184, 349, 256, 358 Annotation: Subtype: Link Rect: 168, 311, 282, 320 Annotation: Subtype: Link Rect: 53, 265, 153, 273 Annotation: Subtype: Link Rect: 279, 225, 293, 235 Annotation: Subtype: Link Rect: 53, 217, 133, 225 Annotation: Subtype: Link Rect: 202, 188, 293, 197 Annotation: Subtype: Link Rect: 53, 180, 80, 187 Annotation: Subtype: Link Rect: 212, 150, 293, 159 Annotation: Subtype: Link Rect: 53, 142, 75, 149 Annotation: Subtype: Link Rect: 53, 103, 130, 112 Annotation: Subtype: Link Rect: 490, 424, 551, 433 Annotation: Subtype: Link Rect: 312, 415, 342, 423 Annotation: Subtype: Link Rect: 330, 368, 430, 377 Annotation: Subtype: Link Rect: 504, 339, 551, 348 Annotation: Subtype: Link Rect: 312, 329, 387, 339 Annotation: Subtype: Link Rect: 473, 301, 551, 310 Annotation: Subtype: Link Rect: 312, 293, 332, 300 Annotation: Subtype: Link Rect: 383, 235, 502, 244 Annotation: Subtype: Link Rect: 428, 207, 528, 216 Annotation: Subtype: Link Rect: 312, 169, 421, 178 Annotation: Subtype: Link Rect: 449, 140, 529, 150 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 251, 706, 293, 716 Annotation: Subtype: Link Rect: 53, 699, 100, 706 Annotation: Subtype: Link Rect: 53, 669, 142, 678 Annotation: Subtype: Link Rect: 100, 602, 192, 612 Annotation: Subtype: Link Rect: 90, 564, 172, 574 Annotation: Subtype: Link Rect: 118, 536, 236, 545 Annotation: Subtype: Link Rect: 53, 508, 168, 517 Annotation: Subtype: Link Rect: 156, 471, 243, 479 Annotation: Subtype: Link Rect: 53, 432, 136, 441 Annotation: Subtype: Link Rect: 53, 394, 147, 403 Annotation: Subtype: Link Rect: 158, 367, 260, 375 Annotation: Subtype: Link Rect: 53, 328, 132, 337 Annotation: Subtype: Link Rect: 250, 299, 293, 309 Annotation: Subtype: Link Rect: 53, 292, 107, 299 Annotation: Subtype: Link Rect: 227, 262, 293, 271 Annotation: Subtype: Link Rect: 53, 252, 97, 261 Annotation: Subtype: Link Rect: 191, 224, 268, 233 Annotation: Subtype: Link Rect: 127, 195, 189, 205 Annotation: Subtype: Link Rect: 53, 157, 171, 167 Annotation: Subtype: Link Rect: 53, 140, 152, 148 Annotation: Subtype: Link Rect: 53, 101, 141, 110 Annotation: Subtype: Link Rect: 434, 697, 544, 706 Annotation: Subtype: Link Rect: 312, 650, 422, 659 Annotation: Subtype: Link Rect: 348, 612, 427, 621 Annotation: Subtype: Link Rect: 509, 555, 551, 564 Annotation: Subtype: Link Rect: 312, 547, 376, 554 Annotation: Subtype: Link Rect: 312, 508, 437, 517 Annotation: Subtype: Link Rect: 312, 470, 406, 479 Annotation: Subtype: Link Rect: 452, 422, 551, 432 Annotation: Subtype: Link Rect: 312, 415, 334, 422 Annotation: Subtype: Link Rect: 442, 366, 545, 375 Annotation: Subtype: Link Rect: 312, 318, 402, 328 Annotation: Subtype: Link Rect: 312, 291, 425, 299 Annotation: Subtype: Link Rect: 312, 252, 436, 261 Annotation: Subtype: Link Rect: 472, 224, 551, 233 Annotation: Subtype: Link Rect: 312, 216, 353, 223 Annotation: Subtype: Link Rect: 363, 177, 463, 186 Annotation: Subtype: Link Rect: 423, 158, 490, 167 Annotation: Subtype: Link Rect: 312, 120, 430, 129 Annotation: Subtype: Link Rect: 418, 82, 505, 91 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 167, 687, 291, 697 Annotation: Subtype: Link Rect: 97, 650, 179, 659 Annotation: Subtype: Link Rect: 160, 631, 271, 640 Annotation: Subtype: Link Rect: 53, 604, 159, 612 Annotation: Subtype: Link Rect: 220, 564, 293, 574 Annotation: Subtype: Link Rect: 53, 557, 70, 564 Annotation: Subtype: Link Rect: 463, 687, 551, 697 Annotation: Subtype: Link Rect: 312, 680, 339, 687 Annotation: Subtype: Link Rect: 315, 593, 341, 602 Annotation: Subtype: Link Rect: 343, 593, 376, 602 Annotation: Subtype: Link Rect: 377, 593, 413, 602 Annotation: Subtype: Link Rect: 415, 593, 438, 602 Annotation: Subtype: Link Rect: 440, 593, 470, 602 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 435, 29, 551, 38 Checksum: 857ee9db Type: CRC32 Checksum: fd6572cab0529acb419c80147659194d Type: MD5 Checksum: 41ba510c921f376bd3af51ff8256e4365a8318a2 Type: SHA-1