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Title:          Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity
Subject:        Prenatal glucocorticoids are routinely administered to pregnant women at risk of preterm delivery in order to improve survival of the newborn.
Keywords:       glucocorticoids, prenatal betamethasone, T cell repertoire, autoimmunity, type 1 diabetes, non-obese diabetic mice, experimental autoimmune encephalomyelitis mice, MRL/lpr
Author:         Anna Gieras
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     Item: 
      Title: Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity
      Children: 
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and Methods
        Children: 
         Item: 
          Title: Mice and Treatment
         Item: 
          Title: Flow Cytometry
         Item: 
          Title: Thymocyte Sensitivity to Betamethasone
         Item: 
          Title: Autologous Mixed Lymphocyte 
Reaction (AMLR)
         Item: 
          Title: Disease Scoring
          Children: 
           Item: 
            Title: MRL/lpr Mice
            Children: 
             Item: 
              Title: Measurement of Double-Stranded (ds) DNA Autoantibodies
             Item: 
              Title: Measurement of Proteinuria
           Item: 
            Title: Non-Obese Diabetic (NOD) Mice
           Item: 
            Title: EAE Mouse Model
         Item: 
          Title: Gene Expression Analysis
         Item: 
          Title: Statistics
         Item: 
          Title: Study Approval
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Prenatal Glucocorticoid Treatment Results in Apoptosis of DP Thymocytes in the MRL/lpr Offspring
         Item: 
          Title: Prenatal Betamethasone Treatment Leads to Changes in the T Cell Repertoire of MRL/lpr Offspring
         Item: 
          Title: Prenatal Betamethasone Protects from T1D Development in NOD Mice
         Item: 
          Title: Prenatal Betamethasone Does Not Induce Long Lasting Changes in the Treg Cell Compartment
         Item: 
          Title: Prenatal Betamethasone Has No Effect on Disease in the Context of a Highly Restricted Pathogenic Repertoire
       Item: 
        Title: Discussion
       Item: 
        Title: Ethics Statement
       Item: 
        Title: Author Contributions
       Item: 
        Title: Acknowledgments
       Item: 
        Title: Funding
       Item: 
        Title: Supplementary Material
       Item: 
        Title: References
   Info: 
    Title: Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity
    Author: Anna Gieras
    Subject: Prenatal glucocorticoids are routinely administered to pregnant women at risk of preterm delivery in order to improve survival of the newborn.
    Keywords: glucocorticoids, prenatal betamethasone, T cell repertoire, autoimmunity, type 1 diabetes, non-obese diabetic mice, experimental autoimmune encephalomyelitis mice, MRL/lpr
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   Type: CRC32
  Checksum: e1e1eeaf4738e43cd3204c6c220096ec
   Type: MD5
  Checksum: 416ab549fd4310e6c6f5fdee2c67020eadf5ee8e
   Type: SHA-1
  Checksum: b77d224e6146011c66859eee08808f729a294b7ddfde11768149055481efffa9
   Type: SHA-256