fadbf80c353e3eeacda9d2d3ebeb6c1e intjouenvrespubhea_a2018v15p16.pdf b74ed8dd7ca770520df54d3cf1bd1fc31411f73b intjouenvrespubhea_a2018v15p16.pdf c017b44a13aba411e02a2d67764b84a448f3dd4f652387845783de4f7552f2ae intjouenvrespubhea_a2018v15p16.pdf Title: Patient-Centered Care in Breast Cancer Genetic Clinics Subject: With advances in breast cancer (BC) gene panel testing, risk counseling has become increasingly complex, potentially leading to unmet psychosocial needs. We assessed psychosocial needs and correlates in women initiating testing for high genetic BC risk in clinics in France and Germany, and compared these results with data from a literature review. Among the 442 counselees consecutively approached, 212 (83%) in France and 180 (97%) in Germany, mostly BC patients (81% and 92%, respectively), returned the ‘Psychosocial Assessment in Hereditary Cancer’ questionnaire. Based on the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) BC risk estimation model, the mean BC lifetime risk estimates were 19% and 18% in France and Germany, respectively. In both countries, the most prevalent needs clustered around the “living with cancer” and “children-related issues” domains. In multivariate analyses, a higher number of psychosocial needs were significantly associated with younger age (b = -0.05), higher anxiety (b = 0.78), and having children (b = 1.51), but not with country, educational level, marital status, depression, or loss of a family member due to hereditary cancer. These results are in line with the literature review data. However, this review identified only seven studies that quantitatively addressed psychosocial needs in the BC genetic counseling setting. Current data lack understandings of how cancer risk counseling affects psychosocial needs, and improves patient-centered care in that setting. Keywords: breast cancer; genetic risk; risk counseling; psychosocial needs; distress; service delivery; culture Author: Anne Brédart, Amélie Anota, Julia Dick, Violetta Kuboth, Olivier Lareyre, Antoine De Pauw, Alejandra Cano, Dominique Stoppa-Lyonnet, Rita Schmutzler, Sylvie Dolbeault and Jean-Luc Kop Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.17 CreationDate: Mon Feb 12 15:30:42 2018 CET ModDate: Mon Oct 22 10:34:19 2018 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 360751 bytes Optimized: yes PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- PJDYJO+VnURWPalladioL Type 1 Custom yes yes no 528 0 LCHYTL+URWPalladioL-Ital Type 1 Custom yes yes no 532 0 SEWQFJ+URWPalladioL-Bold Type 1 Custom yes yes no 535 0 SRHOPK+URWPalladioL-Roma Type 1 Custom yes yes no 538 0 FZHUML+CMSY10 Type 1 Builtin yes yes no 541 0 BTFGED+VnURWPalladioL-Bold Type 1 Custom yes yes no 544 0 OXBKYU+TeXGyreAdventor-Bold Type 1 Custom yes yes no 548 0 LWQXII+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 552 0 IRWHZX+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 554 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 314 0 LWLIVD+EURM10 Type 1 Builtin yes yes no 317 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2018-10-23 04:43:07 CEST RepresentationInformation: intjouenvrespubhea_a2018v15p16.pdf ReportingModule: BYTESTREAM, Rel. 1.3 (2007-04-10) LastModified: 2018-10-22 10:34:31 CEST Size: 360751 Format: bytestream Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/octet-stream Checksum: 4b8aed57 Type: CRC32 Checksum: fadbf80c353e3eeacda9d2d3ebeb6c1e Type: MD5 Checksum: b74ed8dd7ca770520df54d3cf1bd1fc31411f73b Type: SHA-1