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Title:          Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity
Subject:        Scientific Reports, doi:10.1038/s41598-018-31312-w
Keywords:       
Author:         Saray Varona
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     Item: 
      Title: Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: VSMC supernatants from TgLOX mice limit cell proliferation. 
         Item: 
          Title: BAPN prevented the decrease in VSMC proliferation evoked by LOX. 
         Item: 
          Title: The negative regulation of VSMC proliferation was independent of LOX-PP. 
         Item: 
          Title: BAPN ameliorated the attenuated vascular remodeling exhibited by TgLOX mice. 
       Item: 
        Title: Discussion
       Item: 
        Title: Materials and Methods
        Children: 
         Item: 
          Title: Animal handling. 
         Item: 
          Title: Carotid artery ligation experiments and morphometric analysis. 
         Item: 
          Title: Immunohistochemistry. 
         Item: 
          Title: Peripheral Blood Analysis. 
         Item: 
          Title: Cell culture. 
         Item: 
          Title: Lentivirus production and VSMC infection. 
         Item: 
          Title: Real-time PCR. 
         Item: 
          Title: Western-blot analysis. 
         Item: 
          Title: Determination of DNA synthesis. 
         Item: 
          Title: Statistical Analysis. 
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Figure 1 Mature LOX and LOX-PP were over-expressed in the vascular wall and in VSMC from TgLOX mice.
       Item: 
        Title: Figure 2 Extracellular forms are involved in the attenuated cell proliferation induced by LOX transgenesis.
       Item: 
        Title: Figure 3 BAPN prevents the reduction in VSMC proliferation induced by LOX transgenesis.
       Item: 
        Title: Figure 4 Over-expression of LOX-PP did not affect VSMC proliferation.
       Item: 
        Title: Figure 5 LOX transgenesis did not affect the systemic and local inflammatory response after carotid artery ligation.
       Item: 
        Title: Figure 6 BAPN ameliorates the reduced vascular remodeling after carotid artery ligation.
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. 
Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. 
</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. 
Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. 
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
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                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
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