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Title:          Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation
Subject:        Nature Communications, doi:10.1038/s41467-018-03704-z
Keywords:       
Author:         Hui Li
Creator:        Springer
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     Item: 
      Title: Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: N-WASP ko in keratinocytes causes chronic skin inflammation
          Destination: B1
         Item: 
          Title: Increased cytokine expression in N-WASP-null back skin
          Destination: B2
         Item: 
          Title: Different immune cells contribute to IL-17 in N-WASP ko mice
          Destination: B3
         Item: 
          Title: Skin inflammation is dependent on keratinocyte-derived IL-23
          Destination: B4
         Item: 
          Title: Primary N-WASP-null keratinocytes express IL-23A in’vitro
          Destination: B5
         Item: 
          Title: N-WASP regulates IL-23 expression by H3K9 dimethylation
          Destination: B6
         Item: 
          Title: N-WASP regulates protein stability of G9a and GLP
          Destination: B7
         Item: 
          Title: N-WASP is associated with chromatin-bound G9a and GLP
          Destination: B8
         Item: 
          Title: TNF regulates IL-23 expression via H3K9 methylation
          Destination: B9
         Item: 
          Title: TNF induces phosphorylation of N-WASP
          Destination: B10
         Item: 
          Title: H3K9me2 is regulating IL-23 expression in human keratinocytes
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       Item: 
        Title: Discussion
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       Item: 
        Title: Methods
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         Item: 
          Title: Mice
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         Item: 
          Title: Barrier assay
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         Item: 
          Title: Cell isolation, culture and in’vitro knockout
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         Item: 
          Title: Inhibitor experiments
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         Item: 
          Title: Subcellular fractionation
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         Item: 
          Title: Flow cytometry
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         Item: 
          Title: ChIP
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         Item: 
          Title: Gene expression analysis
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         Item: 
          Title: Immunofluorescence and immunohistochemistry
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         Item: 
          Title: Human skin samples
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         Item: 
          Title: Biochemical analysis
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         Item: 
          Title: ELISA
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          Title: Statistics
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          Title: Data availability
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        Title: References
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       Item: 
        Title: Acknowledgements
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        Title: Competing interests
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                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. 
Comment 
PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. 
Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. 

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                           <pdfaProperty:description>Copyright </pdfaProperty:description>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article.
The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. 
If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). 
</pdfaProperty:description>
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                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. 
Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. 
</pdfaProperty:description>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. 
Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. 
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
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                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                  <pdfaSchema:prefix>sn</pdfaSchema:prefix>
                  <pdfaSchema:schema>Springer Nature ORCID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
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