e1c070ac208c6faba45f57e9551b77ea pmc_29784925.pdf 777384f9266bc74ffef784b4fbdc4966df5bf804 pmc_29784925.pdf 882618a5372fc522973df0eca247a24ad9b64cd56c2962375a5fea3a73074f13 pmc_29784925.pdf Title: Acrylamide acute neurotoxicity in adult zebrafish Subject: Scientific Reports, doi:10.1038/s41598-018-26343-2 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Mon May 14 16:16:20 2018 CEST ModDate: Tue May 15 13:18:47 2018 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2520420 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DZYXNX+Corbel CID TrueType Identity-H yes yes yes 415 0 BLKTLB+TimesNewRomanPSMT Type 1C WinAnsi yes yes yes 416 0 MinionPro-It Type 1C Custom yes no yes 97 0 KHABBQ+Corbel-Bold2 Type 1C WinAnsi yes yes yes 417 0 CLMGUQ+Corbel2 Type 1C WinAnsi yes yes yes 58 0 EBHYBV+Corbel-Bold CID TrueType Identity-H yes yes yes 59 0 MinionPro-Regular Type 1C Custom yes no yes 60 0 KHABBQ+Corbel-Bold2 Type 1C WinAnsi yes yes yes 297 0 CLMGUQ+Corbel2 Type 1C WinAnsi yes yes yes 451 0 DZYXNX+Corbel CID TrueType Identity-H yes yes yes 449 0 MyriadPro-It Type 1C WinAnsi yes no yes 300 0 EuclidSymbol Type 1C Custom yes no yes 57 0 CLMGUQ+Corbel2 Type 1C WinAnsi yes yes yes 298 0 DZYXNX+Corbel CID TrueType Identity-H yes yes yes 299 0 MinionPro-Bold Type 1C WinAnsi yes no yes 75 0 KHABBQ+Corbel-Bold2 Type 1C WinAnsi yes yes yes 310 0 DZYXNX+Corbel CID TrueType Identity-H yes yes yes 311 0 MyriadPro-It Type 1C WinAnsi yes no yes 312 0 VOYKFN+STIXGeneral-Regular Type 1C Custom yes yes yes 98 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-01-19 07:10:18 CET RepresentationInformation: pmc_29784925.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2018-05-28 03:40:31 CEST Size: 2520420 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 513 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Acrylamide acute neurotoxicity in adult zebrafish Children: Item: Title: Results and Discussion Children: Item: Title: Systemic toxicity. Item: Title: Behavioral effects. Item: Title: Effects on transcriptional level. Item: Title: Effects of ACR on the adult fish brain proteome. Item: Title: Changes in the neurochemical profile. Item: Title: Conclusions Item: Title: Methods Children: Item: Title: Animals and housing. Item: Title: Experimental procedure. Item: Title: Concentration-response analysis for lethality. Item: Title: Behavioral testing. Item: Title: Whole-body cortisol assay. Item: Title: Skin coloration. Item: Title: RNA preparation and qRT-PCR analysis. Item: Title: Proteomic Analysis. Item: Title: Proteomic data Analysis. Item: Title: Analysis of neurochemicals by LC-MS/MS. Item: Title: Data analysis. Item: Title: Data availability. Item: Title: Acknowledgements Item: Title: Figure 1 Behavioral effects of 3 days exposure to 0. Item: Title: Figure 2 Behavioral effects of 3 days exposure to 0. Item: Title: Figure 3 Behavioral effects of 3 days exposure to 0. Item: Title: Figure 4 Effects of 3 days exposure to 0. Item: Title: Figure 5 Expression of selected transcripts related with axonal damage, synaptic vesicle cycling and neurotoxicity in the brain of adult zebrafish exposed to 0. Item: Title: Figure 6 Effects of acrylamide exposure on the adult zebrafish brain proteome. Item: Title: Figure 7 Changes in the profile of neurochemicals in the brain of adult zebrafish control and exposed to 0. Info: Title: Acrylamide acute neurotoxicity in adult zebrafish Subject: Scientific Reports, doi:10.1038/s41598-018-26343-2 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Mon May 14 16:46:20 CEST 2018 ModDate: Tue May 15 13:18:47 CEST 2018 ID: 0x65ffab28be7f0165f9ef9a833bd61479, 0x735e22d614547806e3c5a9aca89300bb Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1319 ImageHeight: 2300 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1650 ImageHeight: 1822 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: 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