e2e3f9bebb6fc75c4ac5ce9b8f87a81f  pmc_29987000.pdf
67ad7eb17993cdd0cdaab22830cb5624fa3a7d73  pmc_29987000.pdf
136ac870705ceb1728a0d29b45ddadbd31ef854ec7877e705418b47448907ae2  pmc_29987000.pdf

Title:          FGF21 gene therapy as treatment for obesity and insulin resistance
Creator:        Arbortext Advanced Print Publisher 9.1.531/W Unicode
Producer:       Acrobat Distiller 10.0.0 (Windows)
CreationDate:   Thu Aug  2 07:23:41 2018 CEST
ModDate:        Thu Aug  2 07:23:41 2018 CEST
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          24
Encrypted:      no
Page size:      595.276 x 782.362 pts
Page rot:       0
File size:      2873185 bytes
Optimized:      yes
PDF version:    1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
HHBJBO+AdvOT55ce2142                 Type 1C           WinAnsi          yes yes no     314  0
HHBJJE+AdvOT61678bbb.B               Type 1C           WinAnsi          yes yes no     346  0
HHBJJF+AdvStPro-B                    Type 1C           WinAnsi          yes yes no     347  0
HHBJKG+AdvSlimb-BK                   Type 1C           WinAnsi          yes yes no     348  0
HHBJKH+AdvSlim-BKI                   Type 1C           WinAnsi          yes yes no     349  0
HHBJKI+AdvPSMP13                     Type 1C           WinAnsi          yes yes no     358  0
HHBJKJ+AdvPSSym                      Type 1C           Custom           yes yes yes    356  0
HHBJLJ+AdvOT5199123b                 Type 1C           WinAnsi          yes yes no     357  0
HHBJGN+AdvOTf1351f0c                 Type 1C           WinAnsi          yes yes no     343  0
HHBJGO+AdvStPro-R                    Type 1C           WinAnsi          yes yes no     344  0
HHBJGP+AdvOTa293a443                 Type 1C           WinAnsi          yes yes no     340  0
HHBJHP+AdvStPro-L                    Type 1C           WinAnsi          yes yes no     336  0
HHBJIA+AdvTTec369687+20              Type 1C           WinAnsi          yes yes no     337  0
HHBJJB+AdvOT5581a231                 Type 1C           WinAnsi          yes yes no     350  0
HHBJJC+AdvStPro-SB                   Type 1C           WinAnsi          yes yes no     315  0
HHBJJD+AdvTT689d5d16.B               Type 1C           WinAnsi          yes yes no     316  0
HHBJLK+AdvTTec369687                 Type 1C           WinAnsi          yes yes no     246  0
HHBJML+AdvTT3713a231+25              Type 1C           Custom           yes yes yes    241  0
HHBJMM+AdvP4C4E74                    Type 1C           Custom           yes yes yes    236  0
HHBJMN+AdvOTa293a443+20              Type 1C           WinAnsi          yes yes no     233  0
HHBJNN+AdvOT36088c38.B               Type 1C           WinAnsi          yes yes no     230  0
HHBKAN+ArialMT                       Type 1C           Custom           yes yes yes    262  0
HHBKCN+Calibri-Bold                  Type 1C           WinAnsi          yes yes no     259  0
HHBKCO+Helvetica-Bold                Type 1C           WinAnsi          yes yes no     256  0
HHBKFO+Calibri                       Type 1C           Custom           yes yes yes    251  0
HHBMBE+Arial-BoldMT                  Type 1C           WinAnsi          yes yes no      86  0
HHCAFJ+AdvTT3713a231+20              Type 1C           WinAnsi          yes yes no     268  0
HHCBCF+AdvPSMP10                     Type 1C           WinAnsi          yes yes no     207  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2022-11-03 02:32:47 CET
 RepresentationInformation: pmc_29987000.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2020-02-24 03:43:41 CET
  Size: 2873185
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF, ISO PDF/A-1, Level B
  PDFMetadata: 
   Objects: 377
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseThumbs
   Info: 
    Title: FGF21 gene therapy as treatment for obesity and insulin resistance
    Creator: Arbortext Advanced Print Publisher 9.1.531/W Unicode
    Producer: Acrobat Distiller 10.0.0 (Windows)
    CreationDate: Thu Aug 02 07:53:41 CEST 2018
    ModDate: Thu Aug 02 07:53:41 CEST 2018
   ID: 0xea87d7174a26092b2d62f3133d04dae4, 0x9a8f5d10b3d2be76a65bf6732d335daa
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 29
      ImageHeight: 6
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 25
      ImageHeight: 4
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 50
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 12
      ImageHeight: 13
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 50
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 59
      ImageHeight: 41
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 298
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 162
      ImageHeight: 163
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 369
      ImageHeight: 277
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 369
      ImageHeight: 277
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 369
      ImageHeight: 277
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 299
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 299
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 298
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 299
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 299
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 228
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 228
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 229
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 220
      ImageHeight: 220
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 453
      ImageHeight: 31
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 224
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 229
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 228
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 229
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 453
      ImageHeight: 33
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 228
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 228
      ImageHeight: 229
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 224
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 224
      ImageHeight: 224
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 346
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 346
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 174
      ImageHeight: 173
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 345
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 346
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 173
      ImageHeight: 173
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 173
      ImageHeight: 173
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 364
      ImageHeight: 273
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 173
      ImageHeight: 172
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 52
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 52
      ImageHeight: 25
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 52
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 53
      ImageHeight: 26
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 53
      ImageHeight: 25
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 366
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 367
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 365
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 366
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 365
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 365
      ImageHeight: 275
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 51
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 216
      ImageHeight: 187
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 267
      ImageHeight: 233
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 188
      ImageHeight: 213
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 267
      ImageHeight: 228
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 187
      ImageHeight: 213
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 213
      ImageHeight: 186
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 24
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 212
      ImageHeight: 187
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 23
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 186
      ImageHeight: 213
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 187
      ImageHeight: 213
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 188
      ImageHeight: 213
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 28
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 49
      ImageHeight: 28
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: HHBKCO+Helvetica-Bold
      FontSubset: true
      FirstChar: 65
      LastChar: 73
      FontDescriptor: 
       FontName: HHBKCO+Helvetica-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -170, -228, 1003, 962
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBKCN+Calibri-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: HHBKCN+Calibri-Bold
       Flags: Nonsymbolic
       FontBBox: -519, -306, 1240, 971
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBKAN+ArialMT
      FontSubset: true
      FirstChar: 2
      LastChar: 181
      FontDescriptor: 
       FontName: HHBKAN+ArialMT
       Flags: Symbolic
       FontBBox: -665, -325, 2000, 1006
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HHCAFJ+AdvTT3713a231+20
      FontSubset: true
      FirstChar: 151
      LastChar: 151
      FontDescriptor: 
       FontName: HHCAFJ+AdvTT3713a231+20
       Flags: Nonsymbolic
       FontBBox: -468, -208, 1708, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHCBCF+AdvPSMP10
      FontSubset: true
      FirstChar: 97
      LastChar: 98
      FontDescriptor: 
       FontName: HHCBCF+AdvPSMP10
       Flags: Nonsymbolic
       FontBBox: 0, -302, 989, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJHP+AdvStPro-L
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: HHBJHP+AdvStPro-L
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1125, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJIA+AdvTTec369687+20
      FontSubset: true
      FirstChar: 134
      LastChar: 150
      FontDescriptor: 
       FontName: HHBJIA+AdvTTec369687+20
       Flags: Nonsymbolic
       FontBBox: -208, -208, 1062, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJGP+AdvOTa293a443
      FontSubset: true
      FirstChar: 35
      LastChar: 252
      FontDescriptor: 
       FontName: HHBJGP+AdvOTa293a443
       Flags: Nonsymbolic
       FontBBox: -41, -197, 968, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBMBE+Arial-BoldMT
      FontSubset: true
      FirstChar: 65
      LastChar: 105
      FontDescriptor: 
       FontName: HHBMBE+Arial-BoldMT
       Flags: Nonsymbolic
       FontBBox: -628, -376, 2000, 1018
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJGN+AdvOTf1351f0c
      FontSubset: true
      FirstChar: 70
      LastChar: 121
      FontDescriptor: 
       FontName: HHBJGN+AdvOTf1351f0c
       Flags: Nonsymbolic
       FontBBox: -41, -197, 1000, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJGO+AdvStPro-R
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: HHBJGO+AdvStPro-R
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1187, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJJE+AdvOT61678bbb.B
      FontSubset: true
      FirstChar: 38
      LastChar: 121
      FontDescriptor: 
       FontName: HHBJJE+AdvOT61678bbb.B
       Flags: Nonsymbolic
       FontBBox: -41, -197, 1062, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJJF+AdvStPro-B
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: HHBJJF+AdvStPro-B
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1302, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJKG+AdvSlimb-BK
      FontSubset: true
      FirstChar: 35
      LastChar: 180
      FontDescriptor: 
       FontName: HHBJKG+AdvSlimb-BK
       Flags: Serif, Nonsymbolic
       FontBBox: -62, -239, 1062, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJKH+AdvSlim-BKI
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: HHBJKH+AdvSlim-BKI
       Flags: Serif, Nonsymbolic
       FontBBox: -72, -239, 1104, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJJB+AdvOT5581a231
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: HHBJJB+AdvOT5581a231
       Flags: Nonsymbolic
       FontBBox: -41, -197, 1031, 906
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJKJ+AdvPSSym
      FontSubset: true
      FirstChar: 2
      LastChar: 170
      FontDescriptor: 
       FontName: HHBJKJ+AdvPSSym
       Flags: Symbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HHBJLJ+AdvOT5199123b
      FontSubset: true
      FirstChar: 65
      LastChar: 122
      FontDescriptor: 
       FontName: HHBJLJ+AdvOT5199123b
       Flags: Nonsymbolic
       FontBBox: -125, -197, 968, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJKI+AdvPSMP13
      FontSubset: true
      FirstChar: 97
      LastChar: 108
      FontDescriptor: 
       FontName: HHBJKI+AdvPSMP13
       Flags: Nonsymbolic
       FontBBox: 0, -302, 958, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJNN+AdvOT36088c38.B
      FontSubset: true
      FirstChar: 66
      LastChar: 117
      FontDescriptor: 
       FontName: HHBJNN+AdvOT36088c38.B
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1052, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJMN+AdvOTa293a443+20
      FontSubset: true
      FirstChar: 146
      LastChar: 148
      FontDescriptor: 
       FontName: HHBJMN+AdvOTa293a443+20
       Flags: Nonsymbolic
       FontBBox: -114, -187, 1125, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJMM+AdvP4C4E74
      FontSubset: true
      FirstChar: 1
      LastChar: 48
      FontDescriptor: 
       FontName: HHBJMM+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HHBJML+AdvTT3713a231+25
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: HHBJML+AdvTT3713a231+25
       Flags: Symbolic
       FontBBox: -10, -302, 989, 906
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HHBJLK+AdvTTec369687
      FontSubset: true
      FirstChar: 43
      LastChar: 215
      FontDescriptor: 
       FontName: HHBJLK+AdvTTec369687
       Flags: Nonsymbolic
       FontBBox: -72, -208, 927, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJBO+AdvOT55ce2142
      FontSubset: true
      FirstChar: 65
      LastChar: 116
      FontDescriptor: 
       FontName: HHBJBO+AdvOT55ce2142
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1000, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBJJC+AdvStPro-SB
      FontSubset: true
      FirstChar: 49
      LastChar: 50
      FontDescriptor: 
       FontName: HHBJJC+AdvStPro-SB
       Flags: Nonsymbolic
       FontBBox: -114, -197, 1250, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: HHBKFO+Calibri
      FontSubset: true
      FirstChar: 2
      LastChar: 147
      FontDescriptor: 
       FontName: HHBKFO+Calibri
       Flags: Symbolic
       FontBBox: -503, -307, 1240, 964
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HHBJJD+AdvTT689d5d16.B
      FontSubset: true
      FirstChar: 62
      LastChar: 62
      FontDescriptor: 
       FontName: HHBJJD+AdvTT689d5d16.B
       Flags: Nonsymbolic
       FontBBox: -20, -208, 989, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 4.2.1-c316 54.253921, 2018/08/02-12:41:07">
<rdf:RDF xmlns:rdf= "http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about=""
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:xmp="http://ns.adobe.com/xap/1.0/"
	xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
	xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
	xmlns:jav="http://www.niso.org/schemas/jav/1.0/"
	xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/"
	xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
<xmp:CreateDate>2018-08-02T12:41:06+05:30</xmp:CreateDate>
<xmp:ModifyDate>2018-08-02T12:41:06+05:30</xmp:ModifyDate>
<xmp:MetadataDate>2018-08-02T12:41:06+05:30</xmp:MetadataDate>
<pdfx:Producer>Acrobat Distiller 10.1.7 (Windows)</pdfx:Producer>
<pdfx:WPS-ARTICLEDOI>10.15252/emmm.201708791</pdfx:WPS-ARTICLEDOI>
<pdfx:WPS-JOURNALDOI>10.1002/(ISSN)1757-4684</pdfx:WPS-JOURNALDOI>
<pdfx:WPS-PROCLEVEL>3</pdfx:WPS-PROCLEVEL>
<jav:journal_article_version>VoR</jav:journal_article_version>
<prism:doi>10.15252/emmm.201708791</prism:doi>
<dc:format>application/pdf</dc:format>
<dc:title>
<rdf:Alt>
	<rdf:li xml:lang="x-default">FGF21 gene therapy as treatment for obesity and insulin resistance</rdf:li> 
</rdf:Alt> 
</dc:title>
<xmpMM:DocumentID>uuid:775b9234-7f26-4dcd-808d-6dfd356d066d</xmpMM:DocumentID>
<xmpMM:InstanceID>uuid:62754b11-1b81-4e39-a06d-94d7dbce0e86</xmpMM:InstanceID>
</rdf:Description>
</rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 336, 532, 339, 544
      Annotation: 
       Subtype: Link
       Rect: 336, 534, 339, 546
      Annotation: 
       Subtype: Link
       Rect: 339, 532, 345, 543
      Annotation: 
       Subtype: Link
       Rect: 72, 169, 159, 176
     Thumb: true
    Page: 
     Label: 2
     Thumb: true
    Page: 
     Label: 3
     Thumb: true
    Page: 
     Label: 4
     Thumb: true
    Page: 
     Label: 5
     Thumb: true
    Page: 
     Label: 6
     Thumb: true
    Page: 
     Label: 7
     Thumb: true
    Page: 
     Label: 8
     Thumb: true
    Page: 
     Label: 9
     Thumb: true
    Page: 
     Label: 10
     Thumb: true
    Page: 
     Label: 11
     Thumb: true
    Page: 
     Label: 12
     Thumb: true
    Page: 
     Label: 13
     Thumb: true
    Page: 
     Label: 14
     Thumb: true
    Page: 
     Label: 15
     Thumb: true
    Page: 
     Label: 16
     Thumb: true
    Page: 
     Label: 17
     Thumb: true
    Page: 
     Label: 18
     Thumb: true
    Page: 
     Label: 19
     Thumb: true
    Page: 
     Label: 20
     Thumb: true
    Page: 
     Label: 21
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 445, 601, 464, 609
      Annotation: 
       Subtype: Link
       Rect: 491, 273, 547, 280
      Annotation: 
       Subtype: Link
       Rect: 319, 261, 331, 269
      Annotation: 
       Subtype: Link
       Rect: 436, 250, 492, 257
      Annotation: 
       Subtype: Link
       Rect: 489, 239, 544, 246
      Annotation: 
       Subtype: Link
       Rect: 318, 227, 356, 235
      Annotation: 
       Subtype: Link
       Rect: 482, 216, 526, 223
      Annotation: 
       Subtype: Link
       Rect: 476, 205, 522, 212
     Thumb: true
    Page: 
     Label: 22
     Thumb: true
    Page: 
     Label: 23
     Thumb: true
    Page: 
     Label: 24
     Thumb: true
  Checksum: c098b977
   Type: CRC32
  Checksum: e2e3f9bebb6fc75c4ac5ce9b8f87a81f
   Type: MD5
  Checksum: 67ad7eb17993cdd0cdaab22830cb5624fa3a7d73
   Type: SHA-1