94c122faf3958ea2d621a8989ce0989b pmc_30042672.pdf ca3de52f9d0f72ac91b3a95fb0073951c5f5a383 pmc_30042672.pdf 7f694159bf9f2731ea966ca7b535889cac9def91dfbae006908b01dfcfe0705e pmc_30042672.pdf Title: Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors Subject: This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into extrasynaptic and synaptic regions of glutamate and GABA synapses. Keywords: G protein-coupled receptor, dopamine receptor, heteroreceptor complexes, oligomerization, Parkinson's diseases, volume transmission, neural plasticity Author: Kjell Fuxe Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Fri Jul 6 14:34:20 2018 CEST ModDate: Fri Jul 6 14:42:21 2018 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 24 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 4055867 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- UACSMC+HelveticaNeueLTStd-MdIt Type 1C Custom yes yes no 81 0 KZPGLA+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 75 0 FZSBHM+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 73 0 IERCIV+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 56 0 SLCXRP+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 51 0 IDWMYB+MinionPro-Regular Type 1C Custom yes yes no 103 0 AXRLIJ+MinionPro-It Type 1C Custom yes yes no 288 0 JCOJZT+MTGU Type 1C Custom yes yes no 286 0 EJCRHO+HelveticaNeueLTStd-Md Type 1C Custom yes yes no 330 0 PJALMP+MinionPro-Bold Type 1C Custom yes yes no 464 0 OBGWMD+MTSY Type 1C Custom yes yes no 1107 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-01-19 07:09:25 CET RepresentationInformation: pmc_30042672.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2020-02-24 03:41:52 CET Size: 4055867 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 1252 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: あひちどの〠いはばちねどのづ〠ごひちのびねどびびどはの〠どの〠えづちぬぴと〠ちのつ〠ぐちひにどのびはの〧び〠いどびづちびづ〺〠きはつふぬちぴどはの〠はて〠こべのちばぴどっ〠ごひちのびねどびびどはの〠ちのつ〠ぐぬちびぴどっどぴべ〠ごとひはふでと〠ざはぬふねづ〠ごひちのびねどびびどはの〠ちのつ〠いはばちねどのづ〠えづぴづひはひづっづばぴはひび Destination: ariclecounter.1 Children: Item: Title: ぉのぴひはつふっぴどはの Destination: section*.2 Item: Title: ざはぬふねづ〠ごひちのびねどびびどはの〠ぉの〠あひちどの〠いぁ〠ぎづふひはのび Destination: section*.3 Children: Item: Title: ごふぢづひは〭ぉのてふのつどぢふぬちひ〠いぁ〠ぎづふひはのび Destination: section*.4 Item: Title: ぎどでひは〭こぴひどちぴちぬ〠いぁ〠ぎづふひはのび Destination: section*.5 Item: Title: きづびは〭がどねぢどっ〠いぁ〠ぎづふひはのび Destination: section*.6 Children: Item: Title: ぁねべでつちぬち Destination: section*.7 Item: Title: ぎふっぬづふび〠ぁっっふねぢづのび Destination: section*.8 Item: Title: いぁ〠ごひちのびねどびびどはの〠どの〠ぴとづ〠ぃづひづぢひちぬ〠ぃはひぴづへ Destination: section*.9 Item: Title: ぉのぴづでひちぴどはの〠はて〠ごひちのびねどぴぴづひ〯ねはつふぬちぴはひ〠こどでのちぬび〠ざどち〠げづっづばぴはひ〭ひづっづばぴはひ〠ぉのぴづひちっぴどはのび〠どの〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.10 Item: Title: ぉのぴづでひちぴどはの〠はて〠こべのちばぴどっ〠ちのつ〠ざはぬふねづ〠ごひちのびねどびびどはの〠ざどち〠げづっづばぴはひ〭げづっづばぴはひ〠ぉのぴづひちっぴどはのび〠ぉの〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.11 Item: Title: ぉのぴづでひちぴどはの〠はて〠こどでのちぬび〠どの〠ぎどでひは〭びぴひどちぴちぬ〠いぁ〠ごひちのびねどびびどはの〠ごとひはふでと〠ざちひどはふび〠ごべばづび〠はて〠いぁ〠げづっづばぴはひび〠ちのつ〠ごとづどひ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.12 Item: Title: いぁ〠きはつふぬちぴどはの〠はて〠ぴとづ〠ぇぬふぴちねちぴづ〠こべのちばびづび〠はの〠ぴとづ〠いはひびちぬ〠こぴひどちぴは〭ぐちぬぬどつちぬ〠ぇぁあぁ〠ぐちぴとぷちべ〠ごとひはふでと〠い〲〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.13 Children: Item: Title: い〲げ〭ぎきいぁげ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.14 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.15 Item: Title: ぁ〲ぁげ〭い〲げ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.16 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.17 Item: Title: ぁ〲ぁげ〭い〲げ〭ねぇぬふげ〵〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.18 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.19 Item: Title: ぎごこ〱〭い〲〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.20 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.21 Item: Title: さのつづひびぴちのつどので〠ぴとづ〠ぉのぴづでひちぴどはの〠はて〠い〲げ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび〠どの〠いはひびちぬ〠こぴひどちぴは〭ぐちぬぬどつちぬ〠ぇぁあぁ〠ぎづふひはのび Destination: section*.22 Item: Title: いぁ〠ねはつふぬちぴどはの〠はて〠でぬふぴちねちぴづ〠びべのちばびづび〠はの〠ぴとづ〠びぴひどちぴは〭づのぴはばづつふのっふぬちひ〯のどでひちぬ〠ばちぴとぷちべ〠ぴとひはふでと〠い〱げ〠とづぴづひはひづっづばぴはひ〠っはねばぬづへづび Destination: section*.23 Children: Item: Title: い〱げ〭ぎきいぁげ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.24 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.25 Item: Title: ぁ〱げ〭い〱げ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.26 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.27 Item: Title: い〱げ〭い〳げ〠えづぴづひはひづっづばぴはひ〠ぃはねばぬづへづび Destination: section*.28 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.29 Item: Title: いぁ〠ねはつふぬちぴどはの〠はて〠ぴとづ〠どびぬちのつ〯びぴひどはびはねづ〠っはねばちひぴねづのぴ〠はて〠ぴとづ〠つはひびちぬ〠びぴひどちぴふね〠どのぶはぬぶどので〠い〴げ〭きくげ〠とづぴづひはひづっづばぴはひ〠っはねばぬづへづび Destination: section*.30 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.31 Item: Title: いぁ〠ねはつふぬちぴどはの〠はて〠びぴひどちぴちぬ〠っとはぬどのづひでどっ〠どのぴづひのづふひはのび〠どのぶはぬぶどので〠ぁ〲ぁげ〭い〲げ〠とづぴづひはひづっづばぴはひ〠っはねばぬづへづび Destination: section*.32 Children: Item: Title: げづぬづぶちのっづ〠てはひ〠ぐちひにどのびはの〧び〠いどびづちびづ Destination: section*.33 Item: Title: いぁ〠ねはつふぬちぴどはの〠はて〠びぴひどちぴちぬ〠ぇぁあぁ〠どのぴづひのづふひはのび〠ばはぴづのぴどちぬぬべ〠どのぶはぬぶどので〠い〵げ〭ぇぁあぁぁ〠とづぴづひはひづっづばぴはひ〠っはねばぬづへづび Destination: section*.34 Item: Title: ぃはのっぬふびどはのび Destination: section*.35 Item: Title: ぁふぴとはひ〠ぃはのぴひどぢふぴどはのび Destination: section*.36 Item: Title: ぁっにのはぷぬづつでねづのぴび Destination: section*.37 Item: Title: げづてづひづのっづび Destination: section*.38 Info: Title: Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors Author: Kjell Fuxe Subject: This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into extrasynaptic and synaptic regions of glutamate and GABA synapses. Keywords: G protein-coupled receptor, dopamine receptor, heteroreceptor complexes, oligomerization, Parkinson's diseases, volume transmission, neural plasticity Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Fri Jul 06 15:04:20 CEST 2018 ModDate: Fri Jul 06 15:12:21 CEST 2018 ID: 0x3fb39293791b9502661ebf6088678fc6, 0xb22de49f45a234498668c30b32786500 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2677 ImageHeight: 1621 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2677 ImageHeight: 1095 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1417 ImageHeight: 1521 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: AXRLIJ+MinionPro-It FontSubset: true FirstChar: 19 LastChar: 237 FontDescriptor: FontName: AXRLIJ+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 1003, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PJALMP+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: PJALMP+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 823, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: UACSMC+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 237 FontDescriptor: FontName: UACSMC+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -133, -205, 995, 731 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: SLCXRP+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 39 LastChar: 124 FontDescriptor: FontName: SLCXRP+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -9, -214, 848, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OBGWMD+MTSY FontSubset: true FirstChar: 67 LastChar: 67 FontDescriptor: FontName: OBGWMD+MTSY Flags: Symbolic, AllCap FontBBox: 0, -83, 724, 583 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: IDWMYB+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: IDWMYB+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: IERCIV+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 124 FontDescriptor: FontName: IERCIV+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -30, -214, 773, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: FZSBHM+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: FZSBHM+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJCRHO+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 39 LastChar: 121 FontDescriptor: FontName: EJCRHO+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: 0, -205, 810, 714 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: KZPGLA+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 39 LastChar: 243 FontDescriptor: FontName: KZPGLA+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: JCOJZT+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: JCOJZT+MTGU Flags: Symbolic FontBBox: 0, -206, 607, 683 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: dvips + MiKTeX GPL Ghostscript 9.0 G protein-coupled receptor, dopamine receptor, heteroreceptor complexes, oligomerization, Parkinson's diseases, volume transmission, neural plasticity 2018-07-06T18:12:21+05:30 2018-07-06T18:04:20+05:30 LaTeX with hyperref package + hypdvips 2018-07-06T18:12:21+05:30 67966084-8374-11e8-0000-22ae019b6246 uuid:b3c8b077-a78b-43b8-8ae1-e5497f326faa application/pdf Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors Kjell Fuxe This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into extrasynaptic and synaptic regions of glutamate and GABA synapses. This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into extrasynaptic and synaptic regions of glutamate and GABA synapses. G protein-coupled receptor dopamine receptor heteroreceptor complexes oligomerization Parkinson's diseases volume transmission neural plasticity Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 217, 755 Annotation: Subtype: Link Rect: 522, 736, 551, 744 Annotation: Subtype: Link Rect: 477, 728, 520, 736 Annotation: Subtype: Link Rect: 520, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 454, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 149, 38 Annotation: Subtype: Link Rect: 153, 30, 213, 38 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 411, 160, 421 Annotation: Subtype: Link Rect: 114, 263, 160, 272 Annotation: Subtype: Link Rect: 76, 67, 160, 76 Annotation: Subtype: Link Rect: 176, 510, 551, 646 Annotation: Subtype: Link Rect: 176, 488, 286, 497 Annotation: Subtype: Link Rect: 303, 486, 409, 496 Annotation: 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Destination: External Annotation: Subtype: Link Rect: 236, 651, 289, 662 Destination: External Annotation: Subtype: Link Rect: 43, 640, 64, 651 Destination: External Annotation: Subtype: Link Rect: 104, 628, 162, 640 Destination: External Annotation: Subtype: Link Rect: 167, 628, 187, 640 Destination: External Annotation: Subtype: Link Rect: 128, 582, 160, 594 Destination: External Annotation: Subtype: Link Rect: 165, 582, 185, 594 Destination: External Annotation: Subtype: Link Rect: 189, 582, 264, 594 Destination: External Annotation: Subtype: Link Rect: 268, 582, 289, 594 Destination: External Annotation: Subtype: Link Rect: 43, 571, 101, 582 Destination: External Annotation: Subtype: Link Rect: 104, 571, 124, 582 Destination: External Annotation: Subtype: Link Rect: 126, 571, 164, 582 Destination: External Annotation: Subtype: Link Rect: 167, 571, 187, 582 Destination: External Annotation: Subtype: Link Rect: 189, 571, 238, 582 Destination: External Annotation: Subtype: Link Rect: 240, 571, 261, 582 Destination: External Annotation: Subtype: Link Rect: 263, 571, 63, 571 Destination: External Annotation: Subtype: Link Rect: 65, 559, 86, 571 Destination: External Annotation: Subtype: Link Rect: 130, 525, 172, 536 Destination: External Annotation: Subtype: Link Rect: 175, 525, 200, 536 Destination: External Annotation: Subtype: Link Rect: 203, 525, 289, 536 Destination: External Annotation: Subtype: Link Rect: 43, 514, 68, 525 Destination: External Annotation: Subtype: Link Rect: 270, 410, 65, 410 Destination: External Annotation: Subtype: Link Rect: 69, 399, 94, 410 Destination: External Annotation: Subtype: Link Rect: 94, 399, 101, 410 Destination: External Annotation: Subtype: Link Rect: 106, 399, 193, 410 Destination: External Annotation: Subtype: Link Rect: 198, 399, 223, 410 Destination: External Annotation: Subtype: Link Rect: 227, 399, 82, 399 Destination: External Annotation: Subtype: Link Rect: 85, 388, 105, 399 Destination: External Annotation: Subtype: Link Rect: 113, 239, 133, 250 Destination: External Annotation: Subtype: Link Rect: 138, 239, 163, 250 Destination: External Annotation: Subtype: Link Rect: 163, 239, 170, 250 Destination: External Annotation: Subtype: Link Rect: 175, 239, 260, 250 Destination: External Annotation: Subtype: Link Rect: 265, 239, 285, 250 Destination: External Annotation: Subtype: Link Rect: 144, 101, 183, 113 Destination: External Annotation: Subtype: Link Rect: 186, 101, 206, 113 Destination: External Annotation: Subtype: Link Rect: 47, 78, 113, 90 Destination: External Annotation: Subtype: Link Rect: 117, 78, 137, 90 Destination: External Annotation: Subtype: Link Rect: 394, 697, 437, 708 Destination: External Annotation: Subtype: Link Rect: 441, 697, 465, 708 Destination: External Annotation: Subtype: Link Rect: 465, 697, 471, 708 Destination: External Annotation: Subtype: Link Rect: 456, 685, 523, 697 Destination: External Annotation: Subtype: Link Rect: 527, 685, 548, 697 Destination: External Annotation: Subtype: Link Rect: 374, 662, 425, 674 Destination: External Annotation: Subtype: Link Rect: 429, 662, 449, 674 Destination: External Annotation: Subtype: Link Rect: 450, 617, 502, 628 Destination: External Annotation: Subtype: Link Rect: 506, 617, 526, 628 Destination: External Annotation: Subtype: Link Rect: 530, 617, 325, 617 Destination: External Annotation: Subtype: Link Rect: 330, 605, 350, 617 Destination: External Annotation: Subtype: Link Rect: 354, 605, 422, 617 Destination: External Annotation: Subtype: Link Rect: 426, 605, 446, 617 Destination: External Annotation: Subtype: Link Rect: 307, 559, 375, 571 Destination: External Annotation: Subtype: Link Rect: 380, 559, 400, 571 Destination: External Annotation: Subtype: Link Rect: 405, 559, 474, 571 Destination: External Annotation: Subtype: Link Rect: 479, 559, 499, 571 Destination: External Annotation: Subtype: Link Rect: 504, 559, 549, 571 Destination: External Annotation: Subtype: Link Rect: 304, 548, 329, 559 Destination: External Annotation: Subtype: Link Rect: 334, 548, 358, 559 Destination: External Annotation: Subtype: Link Rect: 364, 548, 388, 559 Destination: External Annotation: Subtype: Link Rect: 388, 548, 395, 559 Destination: External Annotation: Subtype: Link Rect: 401, 548, 425, 559 Destination: External Annotation: Subtype: Link Rect: 431, 548, 484, 559 Destination: External Annotation: Subtype: Link Rect: 490, 548, 510, 559 Destination: External Annotation: Subtype: Link Rect: 516, 548, 356, 548 Destination: External Annotation: Subtype: Link Rect: 359, 536, 383, 548 Destination: External Annotation: Subtype: Link Rect: 387, 536, 411, 548 Destination: External Annotation: Subtype: Link Rect: 414, 536, 517, 548 Destination: External Annotation: Subtype: Link Rect: 521, 536, 546, 548 Destination: External Annotation: Subtype: Link Rect: 505, 502, 549, 514 Destination: External Annotation: Subtype: Link Rect: 304, 491, 328, 502 Destination: External Annotation: Subtype: Link Rect: 343, 456, 388, 468 Destination: External Annotation: Subtype: Link Rect: 393, 456, 418, 468 Destination: External Annotation: Subtype: Link Rect: 423, 456, 448, 468 Destination: External Annotation: Subtype: Link Rect: 307, 388, 355, 399 Destination: External Annotation: Subtype: Link Rect: 358, 388, 378, 399 Destination: External Annotation: Subtype: Link Rect: 380, 388, 421, 399 Destination: External Annotation: Subtype: Link Rect: 423, 388, 447, 399 Destination: External Annotation: Subtype: Link Rect: 487, 365, 549, 376 Destination: External Annotation: Subtype: Link Rect: 304, 353, 324, 365 Destination: External Annotation: Subtype: Link Rect: 480, 319, 525, 330 Destination: External Annotation: Subtype: Link Rect: 529, 319, 549, 330 Destination: External Annotation: Subtype: Link Rect: 304, 307, 352, 319 Destination: External Annotation: Subtype: Link Rect: 356, 307, 376, 319 Destination: External Annotation: Subtype: Link Rect: 379, 307, 428, 319 Destination: External Annotation: Subtype: Link Rect: 432, 307, 452, 319 Destination: External Annotation: Subtype: Link Rect: 436, 261, 498, 273 Destination: External Annotation: Subtype: Link Rect: 501, 261, 521, 273 Destination: External Annotation: Subtype: Link Rect: 459, 227, 522, 239 Destination: External Annotation: Subtype: Link Rect: 528, 227, 548, 239 Destination: External Annotation: Subtype: Link Rect: 379, 124, 435, 135 Destination: External Annotation: Subtype: Link Rect: 439, 124, 459, 135 Destination: External Annotation: Subtype: Link Rect: 408, 78, 456, 90 Destination: External Annotation: Subtype: Link Rect: 458, 78, 478, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 4 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 198, 708, 262, 720 Destination: External Annotation: Subtype: Link Rect: 265, 708, 285, 720 Destination: External Annotation: Subtype: Link Rect: 47, 582, 144, 594 Destination: External Annotation: Subtype: Link Rect: 147, 582, 167, 594 Destination: External Annotation: Subtype: Link Rect: 91, 548, 133, 560 Destination: External Annotation: Subtype: Link Rect: 136, 548, 160, 560 Destination: External Annotation: Subtype: Link Rect: 163, 548, 228, 560 Destination: External Annotation: Subtype: Link Rect: 231, 548, 251, 560 Destination: External Annotation: Subtype: Link Rect: 254, 548, 105, 548 Destination: External Annotation: Subtype: Link Rect: 108, 537, 128, 548 Destination: External Annotation: Subtype: Link Rect: 164, 479, 208, 491 Destination: External Annotation: Subtype: Link Rect: 211, 479, 232, 491 Destination: External Annotation: Subtype: Link Rect: 235, 479, 83, 479 Destination: External Annotation: Subtype: Link Rect: 86, 468, 106, 479 Destination: External Annotation: Subtype: Link Rect: 110, 468, 175, 479 Destination: External Annotation: Subtype: Link Rect: 178, 468, 198, 479 Destination: External Annotation: Subtype: Link Rect: 156, 388, 202, 399 Destination: External Annotation: Subtype: Link Rect: 208, 388, 232, 399 Destination: External Annotation: Subtype: Link Rect: 101, 319, 147, 331 Destination: External Annotation: Subtype: Link Rect: 149, 319, 174, 331 Destination: External Annotation: Subtype: Link Rect: 177, 319, 197, 331 Destination: External Annotation: Subtype: Link Rect: 270, 273, 66, 273 Destination: External Annotation: Subtype: Link Rect: 70, 262, 91, 273 Destination: External Annotation: Subtype: Link Rect: 127, 170, 162, 182 Destination: External Annotation: Subtype: Link Rect: 166, 170, 186, 182 Destination: External Annotation: Subtype: Link Rect: 98, 136, 138, 147 Destination: External Annotation: Subtype: Link Rect: 140, 136, 165, 147 Destination: External Annotation: Subtype: Link Rect: 165, 136, 172, 147 Destination: External Annotation: Subtype: Link Rect: 216, 67, 258, 78 Destination: External Annotation: Subtype: Link Rect: 260, 67, 285, 78 Destination: External Annotation: Subtype: Link Rect: 390, 697, 435, 708 Destination: External Annotation: Subtype: Link Rect: 439, 697, 460, 708 Destination: External Annotation: Subtype: Link Rect: 464, 697, 514, 708 Destination: External Annotation: Subtype: Link Rect: 519, 697, 539, 708 Destination: External Annotation: Subtype: Link Rect: 371, 640, 413, 651 Destination: External Annotation: Subtype: Link Rect: 416, 640, 441, 651 Destination: External Annotation: Subtype: Link Rect: 371, 628, 423, 640 Destination: External Annotation: Subtype: Link Rect: 425, 628, 445, 640 Destination: External Annotation: Subtype: Link Rect: 357, 559, 397, 571 Destination: External Annotation: Subtype: Link Rect: 400, 559, 425, 571 Destination: External Annotation: Subtype: Link Rect: 424, 502, 465, 514 Destination: External Annotation: Subtype: Link Rect: 467, 502, 492, 514 Destination: External Annotation: Subtype: Link Rect: 540, 491, 360, 491 Destination: External Annotation: Subtype: Link Rect: 363, 479, 384, 491 Destination: External Annotation: Subtype: Link Rect: 509, 456, 325, 456 Destination: External Annotation: Subtype: Link Rect: 329, 445, 349, 456 Destination: External Annotation: Subtype: Link Rect: 342, 353, 416, 365 Destination: External Annotation: Subtype: Link Rect: 421, 353, 441, 365 Destination: External Annotation: Subtype: Link Rect: 307, 319, 396, 330 Destination: External Annotation: Subtype: Link Rect: 398, 319, 418, 330 Destination: External Annotation: Subtype: Link Rect: 421, 319, 441, 330 Destination: External Annotation: Subtype: Link Rect: 484, 261, 549, 273 Destination: External Annotation: Subtype: Link Rect: 304, 250, 324, 261 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 47, 442, 101, 454 Destination: External Annotation: Subtype: Link Rect: 105, 442, 125, 454 Destination: External Annotation: Subtype: Link Rect: 261, 431, 291, 442 Destination: External Annotation: Subtype: Link Rect: 47, 419, 67, 431 Destination: External Annotation: Subtype: Link Rect: 70, 385, 127, 396 Destination: External Annotation: Subtype: Link Rect: 130, 385, 151, 396 Destination: External Annotation: Subtype: Link Rect: 242, 305, 289, 316 Destination: External Annotation: Subtype: Link Rect: 43, 293, 64, 305 Destination: External Annotation: Subtype: Link Rect: 105, 224, 167, 236 Destination: External Annotation: Subtype: Link Rect: 172, 224, 192, 236 Destination: External Annotation: Subtype: Link Rect: 237, 90, 289, 101 Destination: External Annotation: Subtype: Link Rect: 43, 78, 64, 90 Destination: External Annotation: Subtype: Link Rect: 67, 78, 110, 90 Destination: External Annotation: Subtype: Link Rect: 114, 78, 139, 90 Destination: External Annotation: Subtype: Link Rect: 191, 67, 243, 78 Destination: External Annotation: Subtype: Link Rect: 245, 67, 265, 78 Destination: External Annotation: Subtype: Link Rect: 268, 67, 324, 720 Destination: External Annotation: Subtype: Link Rect: 328, 708, 348, 720 Destination: External Annotation: Subtype: Link Rect: 522, 662, 323, 662 Destination: External Annotation: Subtype: Link Rect: 326, 651, 346, 662 Destination: External Annotation: Subtype: Link Rect: 348, 651, 395, 662 Destination: External Annotation: Subtype: Link Rect: 397, 651, 417, 662 Destination: External Annotation: Subtype: Link Rect: 373, 617, 423, 628 Destination: External Annotation: Subtype: Link Rect: 426, 617, 446, 628 Destination: External Annotation: Subtype: Link Rect: 450, 617, 498, 628 Destination: External Annotation: Subtype: Link Rect: 501, 617, 521, 628 Destination: External Annotation: Subtype: Link Rect: 323, 559, 419, 571 Destination: External Annotation: Subtype: Link Rect: 422, 559, 442, 571 Destination: External Annotation: Subtype: Link Rect: 524, 525, 325, 525 Destination: External Annotation: Subtype: Link Rect: 328, 514, 349, 525 Destination: External Annotation: Subtype: Link Rect: 476, 433, 523, 445 Destination: External Annotation: Subtype: Link Rect: 525, 433, 546, 445 Destination: External Annotation: Subtype: Link Rect: 419, 365, 484, 376 Destination: External Annotation: Subtype: Link Rect: 488, 365, 508, 376 Destination: External Annotation: Subtype: Link Rect: 307, 319, 357, 330 Destination: External Annotation: Subtype: Link Rect: 360, 319, 380, 330 Destination: External Annotation: Subtype: Link Rect: 389, 261, 435, 273 Destination: External Annotation: Subtype: Link Rect: 437, 261, 457, 273 Destination: External Annotation: Subtype: Link Rect: 502, 135, 549, 147 Destination: External Annotation: Subtype: Link Rect: 304, 124, 328, 135 Destination: External Annotation: Subtype: Link Rect: 328, 124, 335, 135 Destination: External Annotation: Subtype: Link Rect: 426, 90, 494, 101 Destination: External Annotation: Subtype: Link Rect: 498, 90, 518, 101 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 6 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 90, 697, 127, 708 Destination: External Annotation: Subtype: Link Rect: 129, 697, 149, 708 Destination: External Annotation: Subtype: Link Rect: 138, 628, 221, 640 Destination: External Annotation: Subtype: Link Rect: 223, 628, 247, 640 Destination: External Annotation: Subtype: Link Rect: 249, 628, 289, 640 Destination: External Annotation: Subtype: Link Rect: 43, 617, 68, 628 Destination: External Annotation: Subtype: Link Rect: 104, 571, 154, 582 Destination: External Annotation: Subtype: Link Rect: 158, 571, 178, 582 Destination: External Annotation: Subtype: Link Rect: 183, 571, 242, 582 Destination: External Annotation: Subtype: Link Rect: 246, 571, 266, 582 Destination: External Annotation: Subtype: Link Rect: 227, 548, 262, 559 Destination: External Annotation: Subtype: Link Rect: 265, 548, 285, 559 Destination: External Annotation: Subtype: Link Rect: 231, 514, 289, 525 Destination: External Annotation: Subtype: Link Rect: 43, 502, 64, 514 Destination: External Annotation: Subtype: Link Rect: 215, 491, 266, 502 Destination: External Annotation: Subtype: Link Rect: 268, 491, 289, 502 Destination: External Annotation: Subtype: Link Rect: 43, 479, 132, 491 Destination: External Annotation: Subtype: Link Rect: 137, 479, 162, 491 Destination: External Annotation: Subtype: Link Rect: 276, 468, 64, 468 Destination: External Annotation: Subtype: Link Rect: 68, 456, 88, 468 Destination: External Annotation: Subtype: Link Rect: 103, 422, 187, 433 Destination: External Annotation: Subtype: Link Rect: 189, 422, 214, 433 Destination: External Annotation: Subtype: Link Rect: 214, 422, 221, 433 Destination: External Annotation: Subtype: Link Rect: 223, 422, 244, 433 Destination: External Annotation: Subtype: Link Rect: 246, 422, 270, 433 Destination: External Annotation: Subtype: Link Rect: 126, 365, 235, 376 Destination: External Annotation: Subtype: Link Rect: 241, 365, 266, 376 Destination: External Annotation: Subtype: Link Rect: 255, 330, 63, 330 Destination: External Annotation: Subtype: Link Rect: 65, 319, 86, 330 Destination: External Annotation: Subtype: Link Rect: 88, 319, 108, 330 Destination: External Annotation: Subtype: Link Rect: 110, 319, 194, 330 Destination: External Annotation: Subtype: Link Rect: 196, 319, 221, 330 Destination: External Annotation: Subtype: Link Rect: 223, 319, 247, 330 Destination: External Annotation: Subtype: Link Rect: 250, 319, 274, 330 Destination: External Annotation: Subtype: Link Rect: 47, 250, 127, 261 Destination: External Annotation: Subtype: Link Rect: 129, 250, 149, 261 Destination: External Annotation: Subtype: Link Rect: 152, 250, 215, 261 Destination: External Annotation: Subtype: Link Rect: 218, 250, 238, 261 Destination: External Annotation: Subtype: Link Rect: 240, 250, 261, 261 Destination: External Annotation: Subtype: Link Rect: 120, 193, 199, 204 Destination: External Annotation: Subtype: Link Rect: 202, 193, 222, 204 Destination: External Annotation: Subtype: Link Rect: 47, 67, 97, 78 Destination: External Annotation: Subtype: Link Rect: 105, 67, 130, 78 Destination: External Annotation: Subtype: Link Rect: 137, 67, 231, 78 Destination: External Annotation: Subtype: Link Rect: 238, 67, 263, 78 Destination: External Annotation: Subtype: Link Rect: 270, 67, 386, 720 Destination: External Annotation: Subtype: Link Rect: 390, 708, 415, 720 Destination: External Annotation: Subtype: Link Rect: 424, 706, 462, 716 Destination: External Annotation: Subtype: Link Rect: 465, 708, 471, 716 Destination: External Annotation: Subtype: Link Rect: 385, 502, 425, 514 Destination: External Annotation: Subtype: Link Rect: 430, 502, 450, 514 Destination: External Annotation: Subtype: Link Rect: 455, 502, 475, 514 Destination: External Annotation: Subtype: Link Rect: 480, 502, 520, 514 Destination: External Annotation: Subtype: Link Rect: 525, 502, 546, 514 Destination: External Annotation: Subtype: Link Rect: 357, 388, 447, 399 Destination: External Annotation: Subtype: Link Rect: 452, 388, 477, 399 Destination: External Annotation: Subtype: Link Rect: 482, 388, 506, 399 Destination: External Annotation: Subtype: Link Rect: 511, 388, 536, 399 Destination: External Annotation: Subtype: Link Rect: 536, 388, 543, 399 Destination: External Annotation: Subtype: Link Rect: 543, 388, 549, 399 Destination: External Annotation: Subtype: Link Rect: 304, 376, 367, 388 Destination: External Annotation: Subtype: Link Rect: 371, 376, 391, 388 Destination: External Annotation: Subtype: Link Rect: 521, 353, 327, 353 Destination: External Annotation: Subtype: Link Rect: 332, 342, 353, 353 Destination: External Annotation: Subtype: Link Rect: 358, 342, 449, 353 Destination: External Annotation: Subtype: Link Rect: 454, 342, 479, 353 Destination: External Annotation: Subtype: Link Rect: 479, 342, 486, 353 Destination: External Annotation: Subtype: Link Rect: 491, 342, 516, 353 Destination: External Annotation: Subtype: Link Rect: 521, 342, 546, 353 Destination: External Annotation: Subtype: Link Rect: 307, 204, 353, 216 Destination: External Annotation: Subtype: Link Rect: 359, 204, 383, 216 Destination: External Annotation: Subtype: Link Rect: 383, 204, 390, 216 Destination: External Annotation: Subtype: Link Rect: 395, 204, 485, 216 Destination: External Annotation: Subtype: Link Rect: 491, 204, 515, 216 Destination: External Annotation: Subtype: Link Rect: 520, 204, 546, 216 Destination: External Annotation: Subtype: Link Rect: 471, 101, 519, 113 Destination: External Annotation: Subtype: Link Rect: 525, 101, 546, 113 Destination: External Annotation: Subtype: Link Rect: 487, 90, 326, 90 Destination: External Annotation: Subtype: Link Rect: 330, 78, 350, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 7 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 178, 246, 227, 257 Destination: External Annotation: Subtype: Link Rect: 233, 246, 257, 257 Destination: External Annotation: Subtype: Link Rect: 264, 246, 289, 257 Destination: External Annotation: Subtype: Link Rect: 43, 234, 147, 246 Destination: External Annotation: Subtype: Link Rect: 150, 234, 170, 246 Destination: External Annotation: Subtype: Link Rect: 178, 232, 213, 242 Destination: External Annotation: Subtype: Link Rect: 117, 188, 200, 200 Destination: External Annotation: Subtype: Link Rect: 204, 188, 224, 200 Destination: External Annotation: Subtype: Link Rect: 254, 177, 289, 188 Destination: External Annotation: Subtype: Link Rect: 43, 165, 64, 177 Destination: External Annotation: Subtype: Link Rect: 499, 146, 549, 157 Destination: External Annotation: Subtype: Link Rect: 304, 134, 324, 146 Destination: External Annotation: Subtype: Link Rect: 330, 134, 392, 146 Destination: External Annotation: Subtype: Link Rect: 397, 134, 418, 146 Destination: External Annotation: Subtype: Link Rect: 511, 86, 546, 96 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 8 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 47, 355, 153, 366 Destination: External Annotation: Subtype: Link Rect: 158, 355, 178, 366 Destination: External Annotation: Subtype: Link Rect: 188, 353, 222, 363 Destination: External Annotation: Subtype: Link Rect: 93, 250, 128, 260 Destination: External Annotation: Subtype: Link Rect: 274, 229, 100, 229 Destination: External Annotation: Subtype: Link Rect: 105, 218, 125, 229 Destination: External Annotation: Subtype: Link Rect: 130, 218, 182, 229 Destination: External Annotation: Subtype: Link Rect: 187, 218, 212, 229 Destination: External Annotation: Subtype: Link Rect: 92, 204, 126, 214 Destination: External Annotation: Subtype: Link Rect: 115, 183, 151, 195 Destination: External Annotation: Subtype: Link Rect: 154, 183, 174, 195 Destination: External Annotation: Subtype: Link Rect: 174, 91, 221, 103 Destination: External Annotation: Subtype: Link Rect: 223, 91, 248, 103 Destination: External Annotation: Subtype: Link Rect: 391, 341, 426, 352 Destination: External Annotation: Subtype: Link Rect: 358, 284, 393, 294 Destination: External Annotation: Subtype: Link Rect: 307, 252, 355, 263 Destination: External Annotation: Subtype: Link Rect: 361, 252, 381, 263 Destination: External Annotation: Subtype: Link Rect: 402, 218, 474, 229 Destination: External Annotation: Subtype: Link Rect: 480, 218, 500, 229 Destination: External Annotation: Subtype: Link Rect: 511, 215, 546, 226 Destination: External Annotation: Subtype: Link Rect: 524, 172, 326, 172 Destination: External Annotation: Subtype: Link Rect: 331, 160, 356, 172 Destination: External Annotation: Subtype: Link Rect: 524, 80, 324, 80 Destination: External Annotation: Subtype: Link Rect: 327, 69, 347, 80 Destination: External Annotation: Subtype: Link Rect: 354, 66, 388, 77 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 9 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 47, 251, 93, 262 Destination: External Annotation: Subtype: Link Rect: 95, 251, 115, 262 Destination: External Annotation: Subtype: Link Rect: 160, 88, 194, 99 Destination: External Annotation: Subtype: Link Rect: 124, 77, 159, 87 Destination: External Annotation: Subtype: Link Rect: 151, 65, 185, 76 Destination: External Annotation: Subtype: Link Rect: 487, 135, 524, 147 Destination: External Annotation: Subtype: Link Rect: 527, 135, 548, 147 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 10 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 199, 674, 240, 685 Destination: External Annotation: Subtype: Link Rect: 245, 674, 265, 685 Destination: External Annotation: Subtype: Link Rect: 88, 582, 176, 594 Destination: External Annotation: Subtype: Link Rect: 184, 582, 204, 594 Destination: External Annotation: Subtype: Link Rect: 113, 422, 191, 433 Destination: External Annotation: Subtype: Link Rect: 195, 422, 215, 433 Destination: External Annotation: Subtype: Link Rect: 87, 399, 137, 410 Destination: External Annotation: Subtype: Link Rect: 142, 399, 162, 410 Destination: External Annotation: Subtype: Link Rect: 192, 376, 288, 388 Destination: External Annotation: Subtype: Link Rect: 43, 365, 64, 376 Destination: External Annotation: Subtype: Link Rect: 257, 330, 67, 330 Destination: External Annotation: Subtype: Link Rect: 74, 319, 94, 330 Destination: External Annotation: Subtype: Link Rect: 180, 307, 223, 319 Destination: External Annotation: Subtype: Link Rect: 227, 307, 252, 319 Destination: External Annotation: Subtype: Link Rect: 237, 284, 289, 296 Destination: External Annotation: Subtype: Link Rect: 43, 273, 64, 284 Destination: External Annotation: Subtype: Link Rect: 69, 273, 159, 284 Destination: External Annotation: Subtype: Link Rect: 164, 273, 189, 284 Destination: External Annotation: Subtype: Link Rect: 195, 273, 220, 284 Destination: External Annotation: Subtype: Link Rect: 81, 67, 134, 78 Destination: External Annotation: Subtype: Link Rect: 136, 67, 157, 78 Destination: External Annotation: Subtype: Link Rect: 307, 639, 362, 651 Destination: External Annotation: Subtype: Link Rect: 367, 639, 387, 651 Destination: External Annotation: Subtype: Link Rect: 393, 639, 446, 651 Destination: External Annotation: Subtype: Link Rect: 451, 639, 472, 651 Destination: External Annotation: Subtype: Link Rect: 477, 639, 523, 651 Destination: External Annotation: Subtype: Link Rect: 529, 639, 549, 651 Destination: External Annotation: Subtype: Link Rect: 304, 628, 329, 639 Destination: External Annotation: Subtype: Link Rect: 332, 628, 418, 639 Destination: External Annotation: Subtype: Link Rect: 422, 628, 447, 639 Destination: External Annotation: Subtype: Link Rect: 447, 628, 453, 639 Destination: External Annotation: Subtype: Link Rect: 456, 628, 481, 639 Destination: External Annotation: Subtype: Link Rect: 485, 628, 509, 639 Destination: External Annotation: Subtype: Link Rect: 512, 628, 326, 628 Destination: External Annotation: Subtype: Link Rect: 332, 617, 352, 628 Destination: External Annotation: Subtype: Link Rect: 361, 614, 396, 625 Destination: External Annotation: Subtype: Link Rect: 328, 582, 374, 594 Destination: External Annotation: Subtype: Link Rect: 379, 582, 399, 594 Destination: External Annotation: Subtype: Link Rect: 404, 582, 449, 594 Destination: External Annotation: Subtype: Link Rect: 453, 582, 473, 594 Destination: External Annotation: Subtype: Link Rect: 478, 582, 498, 594 Destination: External Annotation: Subtype: Link Rect: 307, 548, 401, 559 Destination: External Annotation: Subtype: Link Rect: 408, 548, 433, 559 Destination: External Annotation: Subtype: Link Rect: 480, 525, 328, 525 Destination: External Annotation: Subtype: Link Rect: 334, 513, 354, 525 Destination: External Annotation: Subtype: Link Rect: 518, 468, 325, 468 Destination: External Annotation: Subtype: Link Rect: 328, 456, 349, 468 Destination: External Annotation: Subtype: Link Rect: 352, 456, 439, 468 Destination: External Annotation: Subtype: Link Rect: 442, 456, 467, 468 Destination: External Annotation: Subtype: Link Rect: 376, 387, 429, 399 Destination: External Annotation: Subtype: Link Rect: 431, 387, 451, 399 Destination: External Annotation: Subtype: Link Rect: 503, 296, 549, 307 Destination: External Annotation: Subtype: Link Rect: 304, 284, 329, 296 Destination: External Annotation: Subtype: Link Rect: 333, 284, 353, 296 Destination: External Annotation: Subtype: Link Rect: 358, 284, 444, 296 Destination: External Annotation: Subtype: Link Rect: 449, 284, 469, 296 Destination: External Annotation: Subtype: Link Rect: 474, 284, 521, 296 Destination: External Annotation: Subtype: Link Rect: 525, 284, 546, 296 Destination: External Annotation: Subtype: Link Rect: 370, 239, 441, 250 Destination: External Annotation: Subtype: Link Rect: 444, 239, 464, 250 Destination: External Annotation: Subtype: Link Rect: 349, 193, 391, 204 Destination: External Annotation: Subtype: Link Rect: 393, 193, 418, 204 Destination: External Annotation: Subtype: Link Rect: 421, 193, 523, 204 Destination: External Annotation: Subtype: Link Rect: 525, 193, 546, 204 Destination: External Annotation: Subtype: Link Rect: 435, 158, 519, 170 Destination: External Annotation: Subtype: Link Rect: 525, 158, 546, 170 Destination: External Annotation: Subtype: Link Rect: 398, 124, 449, 135 Destination: External Annotation: Subtype: Link Rect: 451, 124, 471, 135 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 11 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 222, 561, 265, 573 Destination: External Annotation: Subtype: Link Rect: 268, 561, 289, 573 Destination: External Annotation: Subtype: Link Rect: 43, 550, 88, 561 Destination: External Annotation: Subtype: Link Rect: 92, 550, 117, 561 Destination: External Annotation: Subtype: Link Rect: 121, 550, 146, 561 Destination: External Annotation: Subtype: Link Rect: 150, 550, 205, 561 Destination: External Annotation: Subtype: Link Rect: 210, 550, 230, 561 Destination: External Annotation: Subtype: Link Rect: 234, 550, 289, 561 Destination: External Annotation: Subtype: Link Rect: 43, 538, 64, 550 Destination: External Annotation: Subtype: Link Rect: 164, 504, 208, 515 Destination: External Annotation: Subtype: Link Rect: 213, 504, 233, 515 Destination: External Annotation: Subtype: Link Rect: 237, 504, 289, 515 Destination: External Annotation: Subtype: Link Rect: 43, 492, 64, 504 Destination: External Annotation: Subtype: Link Rect: 67, 492, 112, 504 Destination: External Annotation: Subtype: Link Rect: 115, 492, 136, 504 Destination: External Annotation: Subtype: Link Rect: 174, 470, 250, 481 Destination: External Annotation: Subtype: Link Rect: 252, 470, 273, 481 Destination: External Annotation: Subtype: Link Rect: 134, 355, 176, 366 Destination: External Annotation: Subtype: Link Rect: 180, 355, 204, 366 Destination: External Annotation: Subtype: Link Rect: 207, 355, 262, 366 Destination: External Annotation: Subtype: Link Rect: 265, 355, 285, 366 Destination: External Annotation: Subtype: Link Rect: 234, 183, 289, 195 Destination: External Annotation: Subtype: Link Rect: 43, 172, 64, 183 Destination: External Annotation: Subtype: Link Rect: 307, 479, 377, 491 Destination: External Annotation: Subtype: Link Rect: 381, 479, 401, 491 Destination: External Annotation: Subtype: Link Rect: 406, 479, 493, 491 Destination: External Annotation: Subtype: Link Rect: 498, 479, 522, 491 Destination: External Annotation: Subtype: Link Rect: 372, 445, 421, 456 Destination: External Annotation: Subtype: Link Rect: 426, 445, 446, 456 Destination: External Annotation: Subtype: Link Rect: 450, 445, 505, 456 Destination: External Annotation: Subtype: Link Rect: 509, 445, 529, 456 Destination: External Annotation: Subtype: Link Rect: 358, 422, 408, 433 Destination: External Annotation: Subtype: Link Rect: 410, 422, 430, 433 Destination: External Annotation: Subtype: Link Rect: 433, 422, 523, 433 Destination: External Annotation: Subtype: Link Rect: 525, 422, 546, 433 Destination: External Annotation: Subtype: Link Rect: 337, 399, 388, 410 Destination: External Annotation: Subtype: Link Rect: 390, 399, 410, 410 Destination: External Annotation: Subtype: Link Rect: 307, 330, 356, 342 Destination: External Annotation: Subtype: Link Rect: 359, 330, 379, 342 Destination: External Annotation: Subtype: Link Rect: 382, 330, 462, 342 Destination: External Annotation: Subtype: Link Rect: 465, 330, 485, 342 Destination: External Annotation: Subtype: Link Rect: 488, 330, 549, 342 Destination: External Annotation: Subtype: Link Rect: 304, 319, 324, 330 Destination: External Annotation: Subtype: Link Rect: 327, 319, 370, 330 Destination: External Annotation: Subtype: Link Rect: 374, 319, 398, 330 Destination: External Annotation: Subtype: Link Rect: 436, 296, 473, 307 Destination: External Annotation: Subtype: Link Rect: 479, 296, 499, 307 Destination: External Annotation: Subtype: Link Rect: 505, 296, 525, 307 Destination: External Annotation: Subtype: Link Rect: 307, 261, 383, 273 Destination: External Annotation: Subtype: Link Rect: 388, 261, 409, 273 Destination: External Annotation: Subtype: Link Rect: 396, 227, 484, 239 Destination: External Annotation: Subtype: Link Rect: 489, 227, 513, 239 Destination: External Annotation: Subtype: Link Rect: 404, 193, 488, 204 Destination: External Annotation: Subtype: Link Rect: 490, 193, 514, 204 Destination: External Annotation: Subtype: Link Rect: 361, 135, 423, 147 Destination: External Annotation: Subtype: Link Rect: 425, 135, 446, 147 Destination: External Annotation: Subtype: Link Rect: 448, 135, 499, 147 Destination: External Annotation: Subtype: Link Rect: 501, 135, 522, 147 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 12 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 178, 697, 219, 708 Destination: External Annotation: Subtype: Link Rect: 221, 697, 246, 708 Destination: External Annotation: Subtype: Link Rect: 175, 640, 240, 651 Destination: External Annotation: Subtype: Link Rect: 244, 640, 264, 651 Destination: External Annotation: Subtype: Link Rect: 268, 640, 289, 651 Destination: External Annotation: Subtype: Link Rect: 43, 628, 102, 640 Destination: External Annotation: Subtype: Link Rect: 105, 628, 129, 640 Destination: External Annotation: Subtype: Link Rect: 155, 594, 209, 605 Destination: External Annotation: Subtype: Link Rect: 212, 594, 232, 605 Destination: External Annotation: Subtype: Link Rect: 231, 559, 289, 571 Destination: External Annotation: Subtype: Link Rect: 43, 548, 68, 559 Destination: External Annotation: Subtype: Link Rect: 77, 525, 141, 536 Destination: External Annotation: Subtype: Link Rect: 146, 525, 171, 536 Destination: External Annotation: Subtype: Link Rect: 176, 525, 232, 536 Destination: External Annotation: Subtype: Link Rect: 237, 525, 258, 536 Destination: External Annotation: Subtype: Link Rect: 47, 468, 97, 479 Destination: External Annotation: Subtype: Link Rect: 99, 468, 120, 479 Destination: External Annotation: Subtype: Link Rect: 122, 468, 142, 479 Destination: External Annotation: Subtype: Link Rect: 47, 390, 99, 402 Destination: External Annotation: Subtype: Link Rect: 102, 390, 122, 402 Destination: External Annotation: Subtype: Link Rect: 47, 333, 101, 344 Destination: External Annotation: Subtype: Link Rect: 106, 333, 126, 344 Destination: External Annotation: Subtype: Link Rect: 131, 333, 196, 344 Destination: External Annotation: Subtype: Link Rect: 201, 333, 221, 344 Destination: External Annotation: Subtype: Link Rect: 351, 571, 388, 582 Destination: External Annotation: Subtype: Link Rect: 392, 571, 412, 582 Destination: External Annotation: Subtype: Link Rect: 416, 571, 460, 582 Destination: External Annotation: Subtype: Link Rect: 464, 571, 488, 582 Destination: External Annotation: Subtype: Link Rect: 485, 456, 549, 468 Destination: External Annotation: Subtype: Link Rect: 304, 445, 324, 456 Destination: External Annotation: Subtype: Link Rect: 329, 445, 384, 456 Destination: External Annotation: Subtype: Link Rect: 389, 445, 409, 456 Destination: External Annotation: Subtype: Link Rect: 447, 110, 482, 121 Destination: External Annotation: Subtype: Link Rect: 365, 67, 415, 78 Destination: External Annotation: Subtype: Link Rect: 418, 67, 438, 78 Destination: External Annotation: Subtype: Link Rect: 440, 67, 460, 78 Destination: External Annotation: Subtype: Link Rect: 462, 67, 506, 78 Destination: External Annotation: Subtype: Link Rect: 508, 67, 529, 78 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 47, 662, 90, 674 Destination: External Annotation: Subtype: Link Rect: 94, 662, 114, 674 Destination: External Annotation: Subtype: Link Rect: 117, 662, 142, 674 Destination: External Annotation: Subtype: Link Rect: 142, 662, 149, 674 Destination: External Annotation: Subtype: Link Rect: 152, 662, 199, 674 Destination: External Annotation: Subtype: Link Rect: 203, 662, 223, 674 Destination: External Annotation: Subtype: Link Rect: 227, 662, 265, 674 Destination: External Annotation: Subtype: Link Rect: 268, 662, 289, 674 Destination: External Annotation: Subtype: Link Rect: 43, 651, 94, 662 Destination: External Annotation: Subtype: Link Rect: 97, 651, 118, 662 Destination: External Annotation: Subtype: Link Rect: 121, 651, 168, 662 Destination: External Annotation: Subtype: Link Rect: 171, 651, 192, 662 Destination: External Annotation: Subtype: Link Rect: 193, 468, 236, 479 Destination: External Annotation: Subtype: Link Rect: 243, 468, 263, 479 Destination: External Annotation: Subtype: Link Rect: 158, 399, 221, 410 Destination: External Annotation: Subtype: Link Rect: 225, 399, 245, 410 Destination: External Annotation: Subtype: Link Rect: 159, 330, 198, 342 Destination: External Annotation: Subtype: Link Rect: 202, 330, 223, 342 Destination: External Annotation: Subtype: Link Rect: 123, 250, 158, 261 Destination: External Annotation: Subtype: Link Rect: 161, 250, 181, 261 Destination: External Annotation: Subtype: Link Rect: 144, 181, 186, 193 Destination: External Annotation: Subtype: Link Rect: 191, 181, 211, 193 Destination: External Annotation: Subtype: Link Rect: 276, 124, 65, 124 Destination: External Annotation: Subtype: Link Rect: 69, 113, 89, 124 Destination: External Annotation: Subtype: Link Rect: 242, 78, 289, 90 Destination: External Annotation: Subtype: Link Rect: 43, 67, 64, 78 Destination: External Annotation: Subtype: Link Rect: 336, 261, 380, 273 Destination: External Annotation: Subtype: Link Rect: 384, 261, 404, 273 Destination: External Annotation: Subtype: Link Rect: 407, 261, 456, 273 Destination: External Annotation: Subtype: Link Rect: 459, 261, 480, 273 Destination: External Annotation: Subtype: Link Rect: 483, 261, 525, 273 Destination: External Annotation: Subtype: Link Rect: 529, 261, 549, 273 Destination: External Annotation: Subtype: Link Rect: 304, 250, 374, 261 Destination: External Annotation: Subtype: Link Rect: 380, 250, 400, 261 Destination: External Annotation: Subtype: Link Rect: 371, 227, 413, 239 Destination: External Annotation: Subtype: Link Rect: 416, 227, 436, 239 Destination: External Annotation: Subtype: Link Rect: 327, 181, 370, 193 Destination: External Annotation: Subtype: Link Rect: 373, 181, 393, 193 Destination: External Annotation: Subtype: Link Rect: 396, 181, 455, 193 Destination: External Annotation: Subtype: Link Rect: 458, 181, 478, 193 Destination: External Annotation: Subtype: Link Rect: 459, 147, 516, 158 Destination: External Annotation: Subtype: Link Rect: 519, 147, 539, 158 Destination: External Annotation: Subtype: Link Rect: 307, 101, 357, 113 Destination: External Annotation: Subtype: Link Rect: 362, 101, 383, 113 Destination: External Annotation: Subtype: Link Rect: 307, 90, 359, 101 Destination: External Annotation: Subtype: Link Rect: 362, 90, 383, 101 Destination: External Annotation: Subtype: Link Rect: 476, 67, 522, 78 Destination: External Annotation: Subtype: Link Rect: 525, 67, 546, 78 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 14 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 67, 308, 148, 320 Destination: External Annotation: Subtype: Link Rect: 151, 308, 171, 320 Destination: External Annotation: Subtype: Link Rect: 307, 708, 377, 720 Destination: External Annotation: Subtype: Link Rect: 385, 708, 405, 720 Destination: External Annotation: Subtype: Link Rect: 412, 708, 432, 720 Destination: External Annotation: Subtype: Link Rect: 440, 708, 513, 720 Destination: External Annotation: Subtype: Link Rect: 521, 708, 546, 720 Destination: External Annotation: Subtype: Link Rect: 347, 662, 412, 674 Destination: External Annotation: Subtype: Link Rect: 416, 662, 441, 674 Destination: External Annotation: Subtype: Link Rect: 378, 571, 427, 582 Destination: External Annotation: Subtype: Link Rect: 430, 571, 450, 582 Destination: External Annotation: Subtype: Link Rect: 530, 536, 324, 536 Destination: External Annotation: Subtype: Link Rect: 328, 525, 352, 536 Destination: External Annotation: Subtype: Link Rect: 355, 525, 380, 536 Destination: External Annotation: Subtype: Link Rect: 523, 491, 323, 491 Destination: External Annotation: Subtype: Link Rect: 326, 479, 346, 491 Destination: External Annotation: Subtype: Link Rect: 348, 479, 389, 491 Destination: External Annotation: Subtype: Link Rect: 391, 479, 416, 491 Destination: External Annotation: Subtype: Link Rect: 432, 378, 476, 389 Destination: External Annotation: Subtype: Link Rect: 480, 378, 505, 389 Destination: External Annotation: Subtype: Link Rect: 503, 355, 549, 366 Destination: External Annotation: Subtype: Link Rect: 304, 343, 329, 355 Destination: External Annotation: Subtype: Link Rect: 526, 170, 324, 170 Destination: External Annotation: Subtype: Link Rect: 327, 158, 348, 170 Destination: External Annotation: Subtype: Link Rect: 351, 158, 412, 170 Destination: External Annotation: Subtype: Link Rect: 416, 158, 436, 170 Destination: External Annotation: Subtype: Link Rect: 439, 158, 522, 170 Destination: External Annotation: Subtype: Link Rect: 525, 158, 546, 170 Destination: External Annotation: Subtype: Link Rect: 461, 124, 549, 135 Destination: External Annotation: Subtype: Link Rect: 304, 113, 324, 124 Destination: External Annotation: Subtype: Link Rect: 328, 113, 422, 124 Destination: External Annotation: Subtype: Link Rect: 426, 113, 446, 124 Destination: External Annotation: Subtype: Link Rect: 451, 113, 485, 124 Destination: External Annotation: Subtype: Link Rect: 490, 113, 510, 124 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 130, 708, 183, 720 Destination: External Annotation: Subtype: Link Rect: 189, 708, 209, 720 Destination: External Annotation: Subtype: Link Rect: 47, 651, 103, 662 Destination: External Annotation: Subtype: Link Rect: 106, 651, 126, 662 Destination: External Annotation: Subtype: Link Rect: 256, 617, 94, 617 Destination: External Annotation: Subtype: Link Rect: 98, 605, 118, 617 Destination: External Annotation: Subtype: Link Rect: 47, 571, 81, 582 Destination: External Annotation: Subtype: Link Rect: 86, 571, 106, 582 Destination: External Annotation: Subtype: Link Rect: 247, 571, 94, 571 Destination: External Annotation: Subtype: Link Rect: 97, 559, 117, 571 Destination: External Annotation: Subtype: Link Rect: 213, 491, 257, 502 Destination: External Annotation: Subtype: Link Rect: 261, 491, 285, 502 Destination: External Annotation: Subtype: Link Rect: 264, 479, 63, 479 Destination: External Annotation: Subtype: Link Rect: 65, 468, 90, 479 Destination: External Annotation: Subtype: Link Rect: 236, 433, 289, 445 Destination: External Annotation: Subtype: Link Rect: 43, 422, 64, 433 Destination: External Annotation: Subtype: Link Rect: 240, 342, 289, 353 Destination: External Annotation: Subtype: Link Rect: 43, 330, 64, 342 Destination: External Annotation: Subtype: Link Rect: 146, 273, 193, 284 Destination: External Annotation: Subtype: Link Rect: 196, 273, 216, 284 Destination: External Annotation: Subtype: Link Rect: 175, 191, 209, 201 Destination: External Annotation: Subtype: Link Rect: 408, 587, 483, 599 Destination: External Annotation: Subtype: Link Rect: 486, 587, 506, 599 Destination: External Annotation: Subtype: Link Rect: 476, 296, 522, 307 Destination: External Annotation: Subtype: Link Rect: 525, 296, 546, 307 Destination: External Annotation: Subtype: Link Rect: 477, 239, 522, 250 Destination: External Annotation: Subtype: Link Rect: 525, 239, 546, 250 Destination: External Annotation: Subtype: Link Rect: 425, 124, 468, 135 Destination: External Annotation: Subtype: Link Rect: 470, 124, 490, 135 Destination: External Annotation: Subtype: Link Rect: 492, 124, 513, 135 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 16 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 156, 662, 228, 674 Destination: External Annotation: Subtype: Link Rect: 235, 662, 259, 674 Destination: External Annotation: Subtype: Link Rect: 207, 628, 263, 640 Destination: External Annotation: Subtype: Link Rect: 267, 628, 287, 640 Destination: External Annotation: Subtype: Link Rect: 127, 571, 191, 582 Destination: External Annotation: Subtype: Link Rect: 195, 571, 215, 582 Destination: External Annotation: Subtype: Link Rect: 124, 216, 171, 227 Destination: External Annotation: Subtype: Link Rect: 173, 216, 198, 227 Destination: External Annotation: Subtype: Link Rect: 255, 181, 289, 193 Destination: External Annotation: Subtype: Link Rect: 43, 170, 64, 181 Destination: External Annotation: Subtype: Link Rect: 177, 90, 210, 101 Destination: External Annotation: Subtype: Link Rect: 212, 90, 232, 101 Destination: External Annotation: Subtype: Link Rect: 307, 569, 341, 579 Destination: External Annotation: Subtype: Link Rect: 340, 319, 424, 330 Destination: External Annotation: Subtype: Link Rect: 427, 319, 447, 330 Destination: External Annotation: Subtype: Link Rect: 449, 319, 473, 330 Destination: External Annotation: Subtype: Link Rect: 530, 170, 324, 170 Destination: External Annotation: Subtype: Link Rect: 328, 158, 352, 170 Destination: External Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 17 Sequence: 17 Annotations: Annotation: Subtype: Link Rect: 66, 342, 162, 351 Annotation: Subtype: Link Rect: 66, 304, 166, 313 Annotation: Subtype: Link Rect: 66, 266, 176, 275 Annotation: Subtype: Link Rect: 292, 209, 52, 229 Annotation: Subtype: Link Rect: 292, 142, 52, 163 Annotation: Subtype: Link Rect: 66, 114, 169, 124 Annotation: Subtype: Link Rect: 66, 68, 166, 76 Annotation: Subtype: Link Rect: 552, 370, 313, 390 Annotation: Subtype: Link Rect: 327, 333, 422, 341 Annotation: Subtype: Link Rect: 415, 304, 511, 313 Annotation: Subtype: Link Rect: 366, 275, 476, 285 Annotation: Subtype: Link Rect: 327, 228, 436, 237 Annotation: Subtype: Link Rect: 410, 181, 506, 190 Annotation: Subtype: Link Rect: 327, 134, 422, 143 Annotation: Subtype: Link Rect: 327, 86, 427, 95 Annotation: Subtype: Link Rect: 43, 28, 149, 37 Annotation: Subtype: Link Rect: 153, 28, 213, 36 Annotation: Subtype: Link Rect: 449, 28, 551, 37 Page: Label: 18 Sequence: 18 Annotations: Annotation: Subtype: Link Rect: 66, 699, 152, 706 Annotation: Subtype: Link Rect: 66, 660, 162, 668 Annotation: Subtype: Link Rect: 66, 622, 166, 631 Annotation: Subtype: Link Rect: 153, 583, 209, 592 Annotation: Subtype: Link Rect: 141, 556, 237, 564 Annotation: Subtype: Link Rect: 189, 528, 238, 536 Annotation: Subtype: Link Rect: 141, 489, 240, 498 Annotation: Subtype: Link Rect: 66, 452, 166, 460 Annotation: Subtype: Link Rect: 141, 413, 220, 422 Annotation: Subtype: Link Rect: 117, 385, 216, 394 Annotation: Subtype: Link Rect: 66, 347, 197, 356 Annotation: Subtype: Link Rect: 219, 311, 290, 318 Annotation: Subtype: Link Rect: 198, 282, 291, 289 Annotation: Subtype: Link Rect: 66, 244, 168, 252 Annotation: Subtype: Link Rect: 102, 205, 172, 214 Annotation: Subtype: Link Rect: 154, 157, 236, 167 Annotation: Subtype: Link Rect: 292, 111, 52, 130 Annotation: Subtype: Link Rect: 66, 72, 164, 82 Annotation: Subtype: Link Rect: 448, 680, 526, 687 Annotation: Subtype: Link Rect: 425, 642, 540, 649 Annotation: Subtype: Link Rect: 327, 612, 410, 621 Annotation: Subtype: Link Rect: 327, 517, 411, 526 Annotation: Subtype: Link Rect: 327, 470, 409, 479 Annotation: Subtype: Link Rect: 363, 422, 443, 432 Annotation: Subtype: Link Rect: 327, 386, 412, 394 Annotation: Subtype: Link Rect: 552, 336, 313, 357 Annotation: Subtype: Link Rect: 327, 301, 442, 308 Annotation: Subtype: Link Rect: 327, 252, 422, 261 Annotation: Subtype: Link Rect: 480, 206, 546, 214 Annotation: Subtype: Link Rect: 470, 167, 551, 176 Annotation: Subtype: Link Rect: 327, 120, 409, 129 Annotation: Subtype: Link Rect: 443, 91, 523, 100 Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 19 Sequence: 19 Annotations: Annotation: Subtype: Link Rect: 143, 699, 193, 706 Annotation: Subtype: Link Rect: 129, 651, 199, 659 Annotation: Subtype: Link Rect: 66, 602, 297, 612 Annotation: Subtype: Link Rect: 102, 564, 206, 573 Annotation: Subtype: Link Rect: 145, 517, 243, 526 Annotation: Subtype: Link Rect: 66, 470, 165, 479 Annotation: Subtype: Link Rect: 66, 422, 144, 432 Annotation: Subtype: Link Rect: 66, 396, 140, 403 Annotation: Subtype: Link Rect: 292, 355, 52, 376 Annotation: Subtype: Link Rect: 95, 328, 205, 337 Annotation: Subtype: Link Rect: 66, 300, 166, 309 Annotation: Subtype: Link Rect: 185, 273, 248, 280 Annotation: Subtype: Link Rect: 66, 233, 142, 242 Annotation: Subtype: Link Rect: 88, 195, 161, 204 Annotation: Subtype: Link Rect: 190, 157, 285, 167 Annotation: Subtype: Link Rect: 118, 131, 198, 138 Annotation: Subtype: Link Rect: 124, 91, 203, 100 Annotation: Subtype: Link Rect: 363, 670, 444, 678 Annotation: Subtype: Link Rect: 399, 631, 499, 640 Annotation: Subtype: Link Rect: 327, 583, 425, 593 Annotation: Subtype: Link Rect: 327, 556, 422, 564 Annotation: Subtype: Link Rect: 327, 517, 430, 526 Annotation: Subtype: Link Rect: 552, 469, 313, 490 Annotation: Subtype: Link Rect: 439, 434, 551, 441 Annotation: Subtype: Link Rect: 327, 395, 426, 403 Annotation: Subtype: Link Rect: 356, 377, 441, 384 Annotation: Subtype: Link Rect: 327, 348, 387, 356 Annotation: Subtype: Link Rect: 486, 311, 545, 318 Annotation: Subtype: Link Rect: 363, 262, 485, 271 Annotation: Subtype: Link Rect: 327, 216, 444, 223 Annotation: Subtype: Link Rect: 327, 167, 436, 176 Annotation: Subtype: Link Rect: 356, 120, 459, 129 Annotation: Subtype: Link Rect: 552, 71, 313, 92 Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 20 Sequence: 20 Annotations: Annotation: Subtype: Link Rect: 66, 680, 178, 687 Annotation: Subtype: Link Rect: 66, 640, 137, 649 Annotation: Subtype: Link Rect: 113, 602, 189, 611 Annotation: Subtype: Link Rect: 66, 566, 142, 574 Annotation: Subtype: Link Rect: 124, 527, 201, 536 Annotation: Subtype: Link Rect: 239, 500, 291, 507 Annotation: Subtype: Link Rect: 66, 462, 152, 469 Annotation: Subtype: Link Rect: 141, 422, 245, 431 Annotation: Subtype: Link Rect: 66, 394, 176, 403 Annotation: Subtype: Link Rect: 95, 367, 160, 375 Annotation: Subtype: Link 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Annotation: Subtype: Link Rect: 379, 131, 452, 138 Annotation: Subtype: Link Rect: 327, 82, 426, 91 Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 21 Sequence: 21 Annotations: Annotation: Subtype: Link Rect: 66, 679, 162, 687 Annotation: Subtype: Link Rect: 66, 546, 169, 555 Annotation: Subtype: Link Rect: 66, 509, 162, 517 Annotation: Subtype: Link Rect: 162, 480, 257, 489 Annotation: Subtype: Link Rect: 225, 452, 290, 460 Annotation: Subtype: Link Rect: 95, 414, 191, 422 Annotation: Subtype: Link Rect: 192, 385, 289, 394 Annotation: Subtype: Link Rect: 150, 347, 249, 356 Annotation: Subtype: Link Rect: 94, 252, 198, 261 Annotation: Subtype: Link Rect: 170, 224, 255, 233 Annotation: Subtype: Link Rect: 66, 186, 169, 195 Annotation: Subtype: Link Rect: 66, 139, 142, 148 Annotation: Subtype: Link Rect: 327, 699, 407, 706 Annotation: Subtype: Link Rect: 453, 631, 550, 640 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Annotation: Subtype: Link Rect: 110, 678, 189, 687 Annotation: Subtype: Link Rect: 95, 650, 194, 659 Annotation: Subtype: Link Rect: 151, 623, 220, 631 Annotation: Subtype: Link Rect: 66, 583, 126, 592 Annotation: Subtype: Link Rect: 66, 546, 166, 555 Annotation: Subtype: Link Rect: 134, 498, 232, 508 Annotation: Subtype: Link Rect: 66, 460, 146, 470 Annotation: Subtype: Link Rect: 66, 423, 166, 432 Annotation: Subtype: Link Rect: 106, 394, 163, 403 Annotation: Subtype: Link Rect: 66, 356, 142, 365 Annotation: Subtype: Link Rect: 66, 311, 131, 318 Annotation: Subtype: Link Rect: 66, 272, 162, 280 Annotation: Subtype: Link Rect: 66, 234, 164, 243 Annotation: Subtype: Link Rect: 66, 176, 165, 186 Annotation: Subtype: Link Rect: 66, 140, 123, 148 Annotation: Subtype: Link Rect: 95, 110, 186, 119 Annotation: Subtype: Link Rect: 102, 83, 178, 91 Annotation: Subtype: Link Rect: 370, 688, 469, 697 Annotation: Subtype: Link Rect: 552, 649, 313, 669 Annotation: Subtype: Link Rect: 414, 613, 475, 621 Annotation: Subtype: Link Rect: 327, 564, 433, 574 Annotation: Subtype: Link Rect: 405, 527, 482, 536 Annotation: Subtype: Link Rect: 327, 489, 384, 498 Annotation: Subtype: Link Rect: 426, 460, 517, 469 Annotation: Subtype: Link Rect: 327, 434, 388, 441 Annotation: Subtype: Link Rect: 406, 405, 466, 413 Annotation: Subtype: Link Rect: 327, 366, 435, 375 Annotation: Subtype: Link Rect: 413, 328, 509, 337 Annotation: Subtype: Link Rect: 370, 299, 476, 309 Annotation: Subtype: Link Rect: 327, 262, 426, 271 Annotation: Subtype: Link Rect: 398, 234, 495, 243 Annotation: Subtype: Link Rect: 440, 205, 521, 214 Annotation: Subtype: Link Rect: 370, 168, 469, 176 Annotation: Subtype: Link Rect: 356, 111, 456, 119 Annotation: Subtype: Link Rect: 366, 82, 469, 91 Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 23 Sequence: 23 Annotations: Annotation: Subtype: Link Rect: 145, 679, 244, 687 Annotation: Subtype: Link Rect: 66, 631, 175, 640 Annotation: Subtype: Link Rect: 66, 593, 170, 602 Annotation: Subtype: Link Rect: 66, 555, 170, 564 Annotation: Subtype: Link Rect: 199, 519, 257, 526 Annotation: Subtype: Link Rect: 66, 470, 175, 479 Annotation: Subtype: Link Rect: 66, 422, 135, 432 Annotation: Subtype: Link Rect: 102, 395, 225, 403 Annotation: Subtype: Link Rect: 66, 357, 189, 365 Annotation: Subtype: Link Rect: 95, 328, 175, 337 Annotation: Subtype: Link Rect: 173, 309, 245, 318 Annotation: Subtype: Link Rect: 164, 281, 259, 290 Annotation: Subtype: Link Rect: 228, 243, 286, 252 Annotation: Subtype: Link Rect: 66, 205, 189, 214 Annotation: Subtype: Link Rect: 292, 167, 52, 187 Annotation: Subtype: Link Rect: 95, 139, 193, 148 Annotation: Subtype: Link Rect: 164, 101, 240, 110 Annotation: Subtype: Link Rect: 394, 697, 455, 706 Annotation: Subtype: Link Rect: 327, 670, 400, 678 Annotation: Subtype: Link Rect: 327, 623, 419, 630 Annotation: Subtype: Link 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Link Rect: 95, 687, 205, 697 Annotation: Subtype: Link Rect: 66, 650, 176, 659 Annotation: Subtype: Link Rect: 66, 621, 160, 631 Annotation: Subtype: Link Rect: 106, 593, 196, 602 Annotation: Subtype: Link Rect: 292, 556, 52, 574 Annotation: Subtype: Link Rect: 327, 698, 427, 706 Annotation: Subtype: Link Rect: 552, 660, 313, 679 Annotation: Subtype: Link Rect: 316, 575, 343, 582 Annotation: Subtype: Link Rect: 345, 575, 377, 582 Annotation: Subtype: Link Rect: 379, 575, 414, 583 Annotation: Subtype: Link Rect: 416, 575, 439, 582 Annotation: Subtype: Link Rect: 441, 574, 470, 583 Annotation: Subtype: Link Rect: 43, 29, 149, 38 Annotation: Subtype: Link Rect: 153, 29, 213, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Checksum: 8c104b43 Type: CRC32 Checksum: 94c122faf3958ea2d621a8989ce0989b Type: MD5 Checksum: ca3de52f9d0f72ac91b3a95fb0073951c5f5a383 Type: SHA-1 Checksum: 7f694159bf9f2731ea966ca7b535889cac9def91dfbae006908b01dfcfe0705e Type: SHA-256