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Title:          Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling
Subject:        Scientific Reports, doi:10.1038/s41598-018-32107-9
Keywords:       
Author:         Ignacio R. Ipharraguerre
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     Item: 
      Title: Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Antimicrobials promote growth independently of the metabolic phenotype. 
         Item: 
          Title: Antimicrobials converge in altering bile acid biosynthesis by gut microbiota. 
         Item: 
          Title: Antimicrobials modify the profile of bile acid in multiple tissues. 
         Item: 
          Title: Antimicrobials enhance the circulating concentration of FGF19. 
         Item: 
          Title: Intestinal protection by antimicrobials is associated with activation of FXR and TGR5 in the intestine. 
         Item: 
          Title: Antimicrobials remodel bile acid signaling in liver and adipose tissue but not in muscle. 
       Item: 
        Title: Discussion
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Animal Experiments. 
         Item: 
          Title: Sample Collection. 
         Item: 
          Title: Explant Assay. 
         Item: 
          Title: Ussing Chamber Assay. 
         Item: 
          Title: Gut Microbiota Analysis. 
         Item: 
          Title: Bile Acid Analysis. 
         Item: 
          Title: Bile Salt Hydrolase Assay. 
         Item: 
          Title: Gene-Expression Analysis. 
         Item: 
          Title: Hormone and Metabolite Quantification. 
         Item: 
          Title: Statistical Analysis. 
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Figure 1 Growth promotion by in-feed antimicrobials (AMA) is paralleled by inconsistent alterations in the metabolic profile of pigs.
       Item: 
        Title: Figure 2 In-feed antimicrobials (AMA) have irregular influence on the intestinal microbiota of pigs.
       Item: 
        Title: Figure 3 Feeding antimicrobials (AMA) to pigs alter the synthesis of secondary bile acids and the profile of bile acids (BA) in a tissue-specific manner.
       Item: 
        Title: Figure 4 Feeding antimicrobials to pigs enhance the circulating concentration of FGF19 by targeting intestinal FXR.
       Item: 
        Title: Figure 5 The enteroprotective action of in-feed antimicrobials in pigs is associated with increased signaling through intestinal FXR and TGR5.
       Item: 
        Title: Figure 6 Feeding antimicrobials to pigs alter bile acid signaling in liver and subcutaneous white adipose (sWAT).
       Item: 
        Title: Figure 7 Model for bile acid (BA)-induced adaptations underlying growth promotion by antimicrobials (AMA) in pigs.
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Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
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The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
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   Type: CRC32
  Checksum: e7beb828d3e6b49ca3ee4e3088ff6c78
   Type: MD5
  Checksum: 44ed99d30cc163692f9de7c784f68b21a1f9224b
   Type: SHA-1
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   Type: SHA-256