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Title:          CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
Subject:        Molecular Metabolism, 19 (2019) 75-85. doi:10.1016/j.molmet.2018.10.010
Author:         Rosalía Rodríguez-Rodríguez
Creator:        Elsevier
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     Item: 
      Title: CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
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       Item: 
        Title: 1. Introduction
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       Item: 
        Title: 2. Materials and methods
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         Item: 
          Title: 2.1. Animals
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         Item: 
          Title: 2.2. Intracerebroventricular administration of leptin
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         Item: 
          Title: 2.3. Stereotaxic microinjection and viral vectors
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         Item: 
          Title: 2.4. BAT temperature measurements
          Destination: slink4
         Item: 
          Title: 2.5. Sample collection and processing
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         Item: 
          Title: 2.6. Plasma analysis
          Destination: slink6
         Item: 
          Title: 2.7. Tissue morphology
          Destination: slink7
         Item: 
          Title: 2.8. Liver triglycerides (TG) quantification
          Destination: slink8
         Item: 
          Title: 2.9. RNA preparation and quantitative RT-PCR
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         Item: 
          Title: 2.10. Western blotting
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         Item: 
          Title: 2.11. Statistical analysis
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       Item: 
        Title: 3. Results
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        Children: 
         Item: 
          Title: 3.1. CPT1C KO mice show impaired diet-induced thermogenesis
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         Item: 
          Title: 3.2. The thermogenic response to central leptin is impaired in CPT1C KO mice
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         Item: 
          Title: 3.3. CPT1C KO mice display an altered expression of hypothalamic leptin signaling markers and ER stress after short-term HF diet ...
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         Item: 
          Title: 3.4. Expression of CPT1C in the VMH is enough to restore short-term diet-induced response in CPT1C KO mice
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         Item: 
          Title: 3.5. Selective inactivation of AMPKα in the VMH was not able to induce BAT thermogenesis and body weight loss in CPT1C KO mice
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       Item: 
        Title: 4. Discussion
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       Item: 
        Title: 5. Conclusions
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       Item: 
        Title: Financial support
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       Item: 
        Title: Conflict of interest
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       Item: 
        Title: Appendix A. Supplementary data
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       Item: 
        Title: References
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   Info: 
    Title: CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
    Author: Rosalía Rodríguez-Rodríguez
    Subject: Molecular Metabolism, 19 (2019) 75-85. doi:10.1016/j.molmet.2018.10.010
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
    CreationDate: Wed Jan 02 02:54:46 CET 2019
    ModDate: Wed Jan 02 02:55:28 CET 2019
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   Type: CRC32
  Checksum: 28d26512d16cce8eab8f0dc9426ffb5c
   Type: MD5
  Checksum: 51e30dae69fb9bab55c258d9e428e2b269187cf0
   Type: SHA-1
  Checksum: e9c2569f6efdf901562d1f2c2f18acbcb8c836bf4add9940363d7dfb93d5f162
   Type: SHA-256