761292374472893313604ccd4a724e7b  pmc_30543676.pdf
ff9a7e70500b0e991eabd22c04ef0429dcf79a2d  pmc_30543676.pdf
eb8492339b20dc6a69cf43da039570ff436dcc1055e13ed85d5778cb359a8cec  pmc_30543676.pdf

Title:          Bin-CE: A comprehensive web application to decide upon the best set of outcomes to be combined in a binary composite endpoint
Author:         Josep Ramon Marsal, Ignacio Ferreira-Gonz#_#x00E1;lez, Aida Ribera, Gerard Oristrell, Jose Ignacio Pijoan, David Garc#_#x00ED;a-Dorado
Creator:        Arbortext Advanced Print Publisher 11.0.3521/W Unicode-x64
Producer:       PDFlib+PDI 9.0.6 (C++/Win64); modified using iTextSharp™ 5.5.3 ©2000-2014 iText Group NV (AGPL-version)
CreationDate:   Tue Dec 11 03:56:43 2018 CET
ModDate:        Tue Dec 11 03:56:52 2018 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          16
Encrypted:      no
Page size:      612 x 792 pts (letter)
Page rot:       0
File size:      1430577 bytes
Optimized:      no
PDF version:    1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
Helvetica                            Type 1            Builtin          yes no  yes      9  0
OpenSans                             Type 1            Builtin          yes no  yes    638  0
Helvetica-Bold                       Type 1            Builtin          yes no  yes     10  0
NXIYDC+UniversATT-Bold               CID TrueType      Identity-H       yes yes yes    639  0
FRAXNX+ArialMT                       CID TrueType      Identity-H       yes yes yes    253  0
PNNZZF+Univers                       Type 1C           Custom           yes yes yes    640  0
Helvetica-Oblique                    Type 1            Builtin          yes no  yes    641  0
MinionPro-Regular                    Type 1            Builtin          yes no  yes     11  0
Helvetica-Condensed-Bold             Type 1            Builtin          yes no  yes    642  0
Helvetica-Condensed                  Type 1            Builtin          yes no  yes     65  0
FFBNHH+ArialNarrow                   CID TrueType      Identity-H       yes yes yes    643  0
ZDSNQA+MinionPro-It                  Type 1C           Custom           yes yes yes     12  0
MinionPro-Bold                       Type 1            Builtin          yes no  yes     13  0
TeX_CM_Maths_Italic                  Type 1            Builtin          yes no  yes     40  0
TeX_CM_Roman                         Type 1            Builtin          yes no  yes     41  0
THADSV+MinionPro-Regular             Type 1C           Custom           yes yes yes     42  0
TeX_CM_Maths_Symbols                 Type 1            Builtin          yes no  yes     43  0
PI_chars_2                           Type 1            Builtin          yes no  yes     44  0
TeX_CM_Maths_Extension               Type 1            Builtin          yes no  yes     81  0
PI_chars_1                           Type 1            Builtin          yes no  yes     82  0
SVSZIH+SymbolGreekU                  CID TrueType      Identity-H       yes yes yes     94  0
BRAHWW+MinionPro-BoldIt              Type 1C           Custom           yes yes yes    182  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-01-19 07:07:41 CET
 RepresentationInformation: pmc_30543676.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2019-07-15 03:37:51 CEST
  Size: 1430577
  Format: PDF
  Version: 1.6
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref030' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref034' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref043' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref041' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref004' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref042' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref040' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref009' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'Lpone.0209000.ref038' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref030' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref043' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref034' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref038' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref009' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref040' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref041' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref042' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'Lpone.0209000.ref004' cannot be found
   ID: PDF-HUL-122
   Offset: 1213974
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 712
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Language: en
   Info: 
    Title: Bin-CE: A comprehensive web application to decide upon the best set of outcomes to be combined in a binary composite endpoint
    Author: Josep Ramon Marsal, Ignacio Ferreira-Gonz#_#x00E1;lez, Aida Ribera, Gerard Oristrell, Jose Ignacio Pijoan, David Garc#_#x00ED;a-Dorado
    Creator: Arbortext Advanced Print Publisher 11.0.3521/W Unicode-x64
    Producer: PDFlib+PDI 9.0.6 (C++/Win64); modified using iTextSharp™ 5.5.3 ©2000-2014 iText Group NV (AGPL-version)
    CreationDate: Tue Dec 11 04:26:43 CET 2018
    ModDate: Tue Dec 11 04:26:52 CET 2018
   ID: 0xd3a34ee342ba8073db1d191edee12c01, 0x44100e2512eb4a787314d19d875e5ba7
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 38
      ImageHeight: 49
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1230
      ImageHeight: 457
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1230
      ImageHeight: 918
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1236
      ImageHeight: 647
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1232
      ImageHeight: 850
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1230
      ImageHeight: 978
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1230
      ImageHeight: 309
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1191
      ImageHeight: 1762
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 453
      ImageHeight: 100
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: FFBNHH+ArialNarrow
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: FRAXNX+ArialMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: SVSZIH+SymbolGreekU
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: NXIYDC+UniversATT-Bold
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: PNNZZF+Univers
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: PNNZZF+Univers
       Flags: Nonsymbolic
       FontBBox: -168, -250, 992, 947
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica-Oblique
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: Helvetica-Oblique
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica-Condensed
      FirstChar: 33
      LastChar: 251
      FontDescriptor: 
       FontName: Helvetica-Condensed
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica-Condensed-Bold
      FirstChar: 33
      LastChar: 251
      FontDescriptor: 
       FontName: Helvetica-Condensed-Bold
       Flags: Symbolic, ForceBold
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Maths_Italic
      FirstChar: 1
      LastChar: 127
      FontDescriptor: 
       FontName: TeX_CM_Maths_Italic
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: Helvetica
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Roman
      FirstChar: 1
      LastChar: 127
      FontDescriptor: 
       FontName: TeX_CM_Roman
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica-Bold
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: Helvetica-Bold
       Flags: Symbolic, ForceBold
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: THADSV+MinionPro-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 4
      FontDescriptor: 
       FontName: THADSV+MinionPro-Regular
       Flags: Nonsymbolic
       FontBBox: -289, -360, 1684, 917
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-Regular
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: MinionPro-Regular
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Maths_Symbols
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: TeX_CM_Maths_Symbols
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: ZDSNQA+MinionPro-It
      FontSubset: true
      FirstChar: 1
      LastChar: 42
      FontDescriptor: 
       FontName: ZDSNQA+MinionPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -201, -360, 1684, 919
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PI_chars_2
      FirstChar: 33
      LastChar: 126
      FontDescriptor: 
       FontName: PI_chars_2
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-Bold
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: MinionPro-Bold
       Flags: Symbolic, ForceBold
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Maths_Extension
      FirstChar: 1
      LastChar: 150
      FontDescriptor: 
       FontName: TeX_CM_Maths_Extension
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: PI_chars_1
      FirstChar: 33
      LastChar: 126
      FontDescriptor: 
       FontName: PI_chars_1
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: BRAHWW+MinionPro-BoldIt
      FontSubset: true
      FirstChar: 1
      LastChar: 23
      FontDescriptor: 
       FontName: BRAHWW+MinionPro-BoldIt
       Flags: Nonsymbolic, Italic, ForceBold
       FontBBox: -230, -360, 1684, 919
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: OpenSans
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: OpenSans
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: NXIYDC+UniversATT-Bold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: NXIYDC+UniversATT-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -229, -250, 986, 955
       FontFile2: true
     Font: 
      BaseFont: SVSZIH+SymbolGreekU
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: SVSZIH+SymbolGreekU
       Flags: Nonsymbolic
       FontBBox: -911, -268, 1320, 928
       FontFile2: true
     Font: 
      BaseFont: FRAXNX+ArialMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: FRAXNX+ArialMT
       Flags: Nonsymbolic
       FontBBox: -665, -325, 2000, 1006
       FontFile2: true
     Font: 
      BaseFont: FFBNHH+ArialNarrow
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: FFBNHH+ArialNarrow
       Flags: Nonsymbolic
       FontBBox: -182, -307, 1000, 1086
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.1.0-jc003">
  <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
    <rdf:Description rdf:about=""
        xmlns:dc="http://purl.org/dc/elements/1.1/"
        xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/"
        xmlns:crossmark="http://crossref.org/crossmark/1.0/"
        xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
        xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
        xmlns:xmp="http://ns.adobe.com/xap/1.0/"
      dc:identifier="doi:10.1371/journal.pone.0209000"
      prism:doi="10.1371/journal.pone.0209000"
      prism:url="http://dx.doi.org/10.1371/journal.pone.0209000"
      crossmark:MajorVersionDate="2018-12-13"
      crossmark:CrossmarkDomainExclusive="false"
      crossmark:DOI="10.1371/journal.pone.0209000"
      pdfx:doi="10.1371/journal.pone.0209000"
      pdfx:CrossmarkMajorVersionDate="2018-12-13"
      pdfx:CrossmarkDomainExclusive="false"
      pdf:Producer="PDFlib+PDI 9.0.6 (C++/Win64); modified using iTextSharp™ 5.5.3 ©2000-2014 iText Group NV (AGPL-version)"
      xmp:ModifyDate="2018-12-11T08:26:52+05:30"
      xmp:MetadataDate="2018-12-11T08:26:52+05:30">
      <dc:creator>
        <rdf:Seq>
          <rdf:li>Josep Ramon Marsal, Ignacio Ferreira-González, Aida Ribera, Gerard Oristrell, Jose Ignacio Pijoan, David García-Dorado</rdf:li>
        </rdf:Seq>
      </dc:creator>
      <dc:title>
        <rdf:Alt>
          <rdf:li xml:lang="x-default">Bin-CE: A comprehensive web application to decide upon the best set of outcomes to be combined in a binary composite endpoint</rdf:li>
        </rdf:Alt>
      </dc:title>
      <crossmark:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>www.plosone.org</rdf:li>
        </rdf:Seq>
      </crossmark:CrossMarkDomains>
      <pdfx:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>www.plosone.org</rdf:li>
        </rdf:Seq>
      </pdfx:CrossMarkDomains>
    </rdf:Description>
  </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 288, 596, 296, 603
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 265, 585, 273, 592
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 479, 80, 484, 90
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 486, 80, 491, 90
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 512, 87, 522
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 501, 87, 511
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 489, 87, 499
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 478, 87, 488
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 466, 87, 476
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 490, 90, 500
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 69, 338, 161, 345
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 327, 79, 334
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 209, 149, 217
       Flags: Print
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 340, 691, 344, 701
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 275, 678, 280, 688
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 285, 678, 289, 688
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 294, 652, 298, 662
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 203, 574, 208, 584
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 210, 574, 215, 584
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 217, 574, 222, 584
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 224, 574, 229, 584
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 234, 574, 243, 584
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 306, 548, 316, 558
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 358, 418, 368, 428
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 456, 418, 465, 428
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 448, 262, 564, 272
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 249, 241, 259
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 266, 119, 270, 129
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 273, 119, 282, 129
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 284, 119, 294, 129
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 506, 704, 516, 714
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 431, 499, 435, 509
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 438, 499, 447, 509
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 363, 473, 372, 483
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 505, 349, 532, 359
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 374, 310, 384, 320
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 266, 297, 276, 307
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 534, 119, 563, 129
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 106, 329, 116
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 93, 344, 103
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 435, 80, 540, 90
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 446, 525, 472, 535
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 380, 447, 400, 457
       Flags: Print
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 203, 173, 212, 183
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 528, 173, 538, 183
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 488, 134, 507, 144
       Flags: Print
       Destination: 77
      Annotation: 
       Subtype: Link
       Rect: 200, 588, 220, 596
       Flags: Print
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 200, 573, 352, 581
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 475, 360, 495, 370
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 200, 478, 220, 486
       Flags: Print
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 200, 434, 352, 442
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 295, 381, 314, 391
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 200, 543, 220, 551
       Flags: Print
       Destination: 77
      Annotation: 
       Subtype: Link
       Rect: 200, 499, 352, 507
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 133, 220, 141
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 200, 80, 352, 88
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 513, 238, 518, 248
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 520, 238, 530, 248
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 532, 238, 541, 248
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 222, 212, 241, 222
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 200, 475, 220, 483
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 200, 403, 352, 411
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 494, 534, 514, 544
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 291, 508, 310, 518
       Flags: Print
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 315, 465, 325, 475
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 203, 309, 232, 319
       Flags: Print
       Destination: 160
      Annotation: 
       Subtype: Link
       Rect: 258, 309, 263, 319
       Flags: Print
       Destination: 77
      Annotation: 
       Subtype: Link
       Rect: 268, 309, 272, 319
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 277, 309, 281, 319
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 286, 309, 291, 319
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 310, 309, 315, 319
       Flags: Print
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 348, 188, 352, 198
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 355, 188, 364, 198
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 366, 188, 376, 198
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 286, 149, 291, 159
       Flags: Print
       Destination: 77
      Annotation: 
       Subtype: Link
       Rect: 257, 106, 276, 116
       Flags: Print
       Destination: 77
      Annotation: 
       Subtype: Link
       Rect: 203, 80, 222, 90
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 200, 624, 220, 632
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 200, 589, 352, 597
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 320, 118, 340, 128
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 200, 275, 220, 283
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 200, 165, 352, 173
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 288, 418, 308, 428
       Flags: Print
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 230, 314, 235, 324
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 254, 314, 266, 324
       Flags: Print
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 510, 184, 566, 194
       Flags: Print
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 382, 119, 386, 129
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 406, 119, 411, 129
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 211, 106, 241, 116
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 477, 106, 506, 116
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 36, 706, 64, 714
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 36, 456, 186, 464
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 284, 378, 313, 388
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 36, 706, 64, 714
       Flags: Print
       Destination: 160
      Annotation: 
       Subtype: Link
       Rect: 36, 533, 186, 541
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 36, 246, 64, 254
       Flags: Print
       Destination: 160
      Annotation: 
       Subtype: Link
       Rect: 36, 72, 186, 80
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 228, 517, 233, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 235, 517, 245, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 247, 517, 256, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 259, 517, 268, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 270, 517, 280, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 282, 517, 292, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 343, 517, 348, 527
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 309, 504, 319, 514
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 520, 478, 530, 488
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 532, 478, 542, 488
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 547, 478, 556, 488
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 492, 465, 567, 475
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 452, 283, 462
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 203, 374, 212, 384
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 234, 335, 263, 345
       Flags: Print
       Destination: 177
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 350, 626, 355, 636
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 360, 626, 364, 636
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 382, 535, 387, 545
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 389, 535, 399, 545
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 401, 535, 410, 545
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 415, 535, 425, 545
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 317, 470, 327, 480
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 329, 470, 339, 480
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 341, 470, 351, 480
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 345, 392, 355, 402
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 357, 392, 367, 402
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 372, 392, 381, 402
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 347, 249, 352, 259
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 354, 249, 359, 259
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 361, 249, 366, 259
       Flags: Print
       Destination: 249
      Annotation: 
       Subtype: Link
       Rect: 368, 249, 378, 259
       Flags: Print
       Destination: 294
      Annotation: 
       Subtype: Link
       Rect: 380, 249, 389, 259
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 394, 249, 404, 259
       Flags: Print
       Destination: 396
      Annotation: 
       Subtype: Link
       Rect: 507, 171, 561, 181
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 158, 303, 168
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 99, 227, 109
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 200, 704, 227, 714
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 659, 227, 669
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 269, 209, 277
       Flags: Print
       Destination: 506
      Annotation: 
       Subtype: Link
       Rect: 449, 259, 566, 267
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 245, 250, 280, 258
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 237, 209, 245
       Flags: Print
       Destination: 506
      Annotation: 
       Subtype: Link
       Rect: 497, 228, 558, 236
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 218, 277, 226
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 302, 218, 337, 226
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 205, 209, 213
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 221, 186, 375, 194
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 173, 209, 181
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 296, 154, 455, 162
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 480, 154, 515, 162
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 141, 209, 149
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 469, 131, 564, 139
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 122, 269, 130
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 295, 122, 329, 130
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 109, 209, 117
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 466, 90, 550, 98
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 81, 291, 89
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 316, 81, 351, 89
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 15
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 200, 706, 209, 714
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 395, 697, 507, 705
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 532, 697, 567, 705
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 684, 209, 692
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 256, 674, 427, 682
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 453, 674, 488, 682
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 661, 209, 669
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 339, 652, 370, 660
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 639, 209, 647
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 429, 620, 459, 628
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 607, 209, 615
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 440, 597, 552, 605
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 245, 588, 280, 596
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 575, 209, 583
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 366, 556, 488, 564
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 513, 556, 548, 564
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 543, 209, 551
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 200, 520, 209, 528
       Flags: Print
       Destination: 3
      Annotation: 
       Subtype: Link
       Rect: 221, 501, 375, 509
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 401, 501, 436, 509
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 488, 209, 496
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 200, 466, 209, 474
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 352, 447, 473, 455
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 499, 447, 534, 455
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 434, 209, 442
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 443, 424, 567, 432
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 415, 245, 423
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 271, 415, 306, 423
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 402, 209, 410
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 200, 379, 209, 387
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 200, 347, 209, 355
       Flags: Print
       Destination: 36
      Annotation: 
       Subtype: Link
       Rect: 501, 347, 575, 355
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 338, 235, 346
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 325, 209, 333
       Flags: Print
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 431, 315, 568, 323
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 306, 252, 314
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 277, 306, 312, 314
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 293, 209, 301
       Flags: Print
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 284, 283, 399, 291
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 425, 283, 460, 291
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 270, 209, 278
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 400, 251, 548, 259
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 242, 256, 250
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 229, 209, 237
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 349, 219, 494, 227
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 519, 219, 554, 227
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 206, 209, 214
       Flags: Print
       Destination: 124
      Annotation: 
       Subtype: Link
       Rect: 474, 197, 574, 205
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 187, 265, 195
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 290, 187, 325, 195
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 174, 209, 182
       Flags: Print
       Destination: 196
      Annotation: 
       Subtype: Link
       Rect: 360, 165, 528, 173
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 155, 256, 163
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 142, 209, 150
       Flags: Print
       Destination: 196
      Annotation: 
       Subtype: Link
       Rect: 273, 133, 385, 141
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 410, 133, 445, 141
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 120, 209, 128
       Flags: Print
       Destination: 196
      Annotation: 
       Subtype: Link
       Rect: 242, 110, 379, 118
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 404, 110, 439, 118
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
    Page: 
     Sequence: 16
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 200, 706, 209, 714
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 400, 697, 543, 705
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 687, 256, 695
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 674, 209, 682
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 200, 652, 209, 660
       Flags: Print
       Destination: 196
      Annotation: 
       Subtype: Link
       Rect: 383, 642, 496, 650
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 521, 642, 556, 650
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 629, 209, 637
       Flags: Print
       Destination: 196
      Annotation: 
       Subtype: Link
       Rect: 495, 620, 556, 628
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 610, 301, 618
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 327, 610, 362, 618
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 597, 209, 605
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 256, 588, 388, 596
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 413, 588, 448, 596
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 575, 209, 583
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 200, 552, 209, 560
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 245, 543, 275, 551
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 530, 209, 538
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 400, 520, 563, 528
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 511, 247, 519
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 273, 511, 308, 519
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 498, 209, 506
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 505, 488, 565, 496
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 479, 301, 487
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 326, 479, 361, 487
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 466, 209, 474
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 221, 456, 545, 464
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 443, 209, 451
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 321, 434, 559, 442
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 424, 351, 432
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 411, 209, 419
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 377, 402, 492, 410
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 518, 402, 553, 410
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 389, 209, 397
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 221, 379, 338, 387
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 363, 379, 398, 387
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 366, 209, 374
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 221, 347, 374, 355
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 400, 347, 435, 355
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 334, 209, 342
       Flags: Print
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 325, 325, 481, 333
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 200, 312, 209, 320
       Flags: Print
       Destination: 219
      Annotation: 
       Subtype: Link
       Rect: 526, 302, 562, 310
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 293, 324, 301
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 350, 293, 385, 301
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 81, 34, 237, 42
       Flags: Print
  Checksum: b67fc8e2
   Type: CRC32
  Checksum: 761292374472893313604ccd4a724e7b
   Type: MD5
  Checksum: ff9a7e70500b0e991eabd22c04ef0429dcf79a2d
   Type: SHA-1
  Checksum: eb8492339b20dc6a69cf43da039570ff436dcc1055e13ed85d5778cb359a8cec
   Type: SHA-256