54b39cffd78fc9e16d7635d1d259f988 RBMO_2018.pdf f4b8e82049321ea3052440f2dba3774485a86391 RBMO_2018.pdf 73c489827a81961012bda20e92ac98bb636936acd35da0981b136ab1da1419ae RBMO_2018.pdf Title: Hysteroscopic septum resection and reproductive medicine: A SWOT analysis Subject: Reproductive BioMedicine Online, 37 (2018) 709-715. doi:10.1016/j.rbmo.2018.09.013 Keywords: Infertility,Metroplasty,Preterm delivery,Recurrent miscarriage,Septate uterus,Septum resection,Spontaneous abortion,Spontaneous abortion Author: Spanish Infertility SWOT Group (SISG) Creator: Elsevier Producer: Adobe PDF Library 10.0.1 CreationDate: Thu Dec 6 06:11:50 2018 CET ModDate: Wed Dec 12 18:16:23 2018 CET Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 345350 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NXWMLB+Quasimoda-Bold Type 1C Custom yes yes yes 1674 0 NXWMLB+Quasimoda-Regular Type 1C Custom yes yes yes 1677 0 NXWMLB+Quasimoda-Medium Type 1C WinAnsi yes yes yes 1679 0 NXWMLB+Quasimoda-SemiBold Type 1C Custom yes yes yes 1681 0 NXWMLB+Quasimoda-Light Type 1C Custom yes yes yes 88 0 NXWMLB+Quasimoda-LightItalic Type 1C Custom yes yes yes 92 0 NXWMLB+Quasimoda-SemiBold-SC700 Type 1C WinAnsi yes yes yes 100 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-07-30 02:10:28 CEST RepresentationInformation: RBMO_2018.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-07-29 12:22:34 CEST Size: 345350 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Hysteroscopic septum resection and reproductive medicine: A SWOT analysis Children: Item: Title: Introduction Item: Title: Strengths Children: Item: Title: Septum resection improves fertility Item: Title: Septum resection decreases miscarriage rate Item: Title: Septum resection decreases preterm delivery and increases term births and live births Item: Title: Septum resection does not delay time to assisted reproductive treatment Item: Title: Septum resection surgery is simple, safe and with reduced morbidity Item: Title: Improves obstetric outcomes regardless of septum size Item: Title: Weaknesses Children: Item: Title: Lack of evidence in randomized trials showing septum resection improves obstetrical outcomes Item: Title: Not recommended in women without poor reproductive outcomes Item: Title: May affect peri-implantation and perinatal outcomes Item: Title: Surgical risks associated with septum resection Item: Title: Non-standardized procedure Item: Title: Direct and indirect costs Item: Title: Opportunities Children: Item: Title: Predisposition to interventionism Item: Title: Generalized reduction in the fear of side-effects of surgery Item: Title: Demand from women and society to solve their problems, such as those related to infertility Item: Title: Patient confidence Item: Title: Improved endometrial assessment after septoplasty Item: Title: Threats Children: Item: Title: Risk of over diagnosis Item: Title: Risk of over-treating a situation that is not actually causing infertility Item: Title: Under-treating a situation that is causing infertility Item: Title: Easy access to information on the Internet overriding medical criteria Item: Title: Conclusions Item: Title: References Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 300 ImageHeight: 401 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 131 ImageHeight: 130 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: NXWMLB+Quasimoda-SemiBold FontSubset: true FirstChar: 31 LastChar: 252 FontDescriptor: FontName: NXWMLB+Quasimoda-SemiBold Flags: Nonsymbolic FontBBox: -182, -276, 1289, 1123 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-SemiBold-SC700 FontSubset: true FirstChar: 84 LastChar: 84 FontDescriptor: FontName: NXWMLB+Quasimoda-SemiBold-SC700 Flags: Nonsymbolic FontBBox: -182, -276, 1289, 1123 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-Light FontSubset: true FirstChar: 26 LastChar: 246 FontDescriptor: FontName: NXWMLB+Quasimoda-Light Flags: Nonsymbolic FontBBox: -168, -279, 1239, 1112 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-Bold FontSubset: true FirstChar: 31 LastChar: 122 FontDescriptor: FontName: NXWMLB+Quasimoda-Bold Flags: Nonsymbolic FontBBox: -184, -279, 1310, 1128 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-LightItalic FontSubset: true FirstChar: 29 LastChar: 246 FontDescriptor: FontName: NXWMLB+Quasimoda-LightItalic Flags: Nonsymbolic, Italic FontBBox: -221, -279, 1239, 1113 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-Regular FontSubset: true FirstChar: 30 LastChar: 237 FontDescriptor: FontName: NXWMLB+Quasimoda-Regular Flags: Nonsymbolic FontBBox: -180, -274, 1261, 1115 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NXWMLB+Quasimoda-Medium FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: NXWMLB+Quasimoda-Medium Flags: Nonsymbolic FontBBox: -181, -274, 1274, 1119 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true XMP: doi:10.1016/j.rbmo.2018.09.013 application/pdf Elsevier Ltd Reproductive BioMedicine Online, 37 (2018) 709-715. doi:10.1016/j.rbmo.2018.09.013 Infertility Metroplasty Preterm delivery Recurrent miscarriage Septate uterus Septum resection Spontaneous abortion Spontaneous abortion Hysteroscopic septum resection and reproductive medicine: A SWOT analysis Spanish Infertility SWOT Group (SISG) M.A. Checa J. Bellver E. Bosch J.J. Espinós F. Fabregues J. Fontes J. García-Velasco A. Requena 2018-12-06T10:41:50+05:30 2018-12-12T18:16:23+01:00 2018-12-12T18:16:23+01:00 Elsevier uuid:51eb34fe-b75d-e742-9cbf-dee279b3037a xmp.did:01801174072068118083A17A29ED4307 xmp.id:01C5BDAE07206811822AFD1B1B1044F9 proof:pdf uuid:d56e5e26-6274-4fa7-ad08-30fc2ecddb91 uuid:fd8cfc10-4791-4a8b-8025-00abb91efa0c xmp.did:01801174072068118083A17A29ED4307 default converted from application/pdf to application/pdf Adobe InDesign CS6 (Macintosh) / 2018-12-06T10:41:50+05:30 Adobe PDF Library 10.0.1 Infertility,Metroplasty,Preterm delivery,Recurrent miscarriage,Septate uterus,Septum resection,Spontaneous abortion,Spontaneous abortion False journal © 2018 Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd. Reproductive BioMedicine Online 1472-6483 37 6 10.1016/j.rbmo.2018.09.013 https://doi.org/10.1016/j.rbmo.2018.09.013 709 715 709-715 December 2018 6.5 2010-04-23 true 10.1016/j.rbmo.2018.09.013 noindex sciencedirect.com elsevier.com sciencedirect.com elsevier.com VoR true 2010-04-23 10.1016/j.rbmo.2018.09.013 sciencedirect.com elsevier.com True Pages: Page: Label: 709 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 519, 662, 554, 623 Annotation: Subtype: Link Rect: 355, 481, 359, 468 ActionDest: 1629 Annotation: Subtype: Link Rect: 359, 481, 363, 468 ActionDest: 1629 Annotation: Subtype: Link Rect: 405, 481, 409, 468 ActionDest: 1629 Annotation: Subtype: Link Rect: 449, 481, 452, 468 ActionDest: 1629 Annotation: Subtype: Link Rect: 190, 469, 193, 456 ActionDest: 1629 Annotation: Subtype: Link Rect: 249, 469, 253, 456 ActionDest: 1629 Annotation: Subtype: Link Rect: 294, 469, 298, 456 ActionDest: 1629 Annotation: Subtype: Link Rect: 373, 469, 377, 456 ActionDest: 1629 Annotation: Subtype: Link Rect: 430, 469, 434, 456 ActionDest: 1629 Page: Label: 710 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 45, 662, 107, 650 ActionDest: 12 Annotation: Subtype: Link Rect: 98, 554, 177, 542 ActionDest: 12 Annotation: Subtype: Link Rect: 45, 479, 183, 467 ActionDest: 12 Annotation: Subtype: Link Rect: 45, 371, 118, 360 ActionDest: 14 Annotation: Subtype: Link Rect: 141, 350, 175, 338 ActionDest: 12 Annotation: Subtype: Link Rect: 42, 339, 82, 327 ActionDest: 12 Annotation: Subtype: Link Rect: 45, 264, 106, 252 ActionDest: 14 Annotation: Subtype: Link Rect: 84, 242, 154, 231 ActionDest: 14 Annotation: Subtype: Link Rect: 262, 694, 329, 682 ActionDest: 14 Annotation: Subtype: Link Rect: 303, 629, 354, 618 ActionDest: 14 Annotation: Subtype: Link Rect: 212, 619, 255, 607 ActionDest: 14 Annotation: Subtype: Link Rect: 215, 597, 307, 585 ActionDest: 12 Annotation: Subtype: Link Rect: 261, 447, 283, 435 ActionDest: 1 Annotation: Subtype: Link Rect: 245, 242, 346, 231 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 726, 529, 714 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 715, 526, 704 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 705, 423, 693 ActionDest: 14 Annotation: Subtype: Link Rect: 430, 683, 523, 671 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 672, 443, 661 ActionDest: 12 Annotation: Subtype: Link Rect: 495, 672, 519, 661 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 662, 428, 650 ActionDest: 14 Annotation: Subtype: Link Rect: 482, 490, 534, 478 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 479, 400, 467 ActionDest: 14 Annotation: Subtype: Link Rect: 385, 436, 525, 424 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 425, 401, 413 ActionDest: 12 Annotation: Subtype: Link Rect: 498, 425, 528, 413 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 414, 423, 403 ActionDest: 12 Annotation: Subtype: Link Rect: 492, 382, 528, 370 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 371, 532, 360 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 361, 413, 349 ActionDest: 12 Annotation: Subtype: Link Rect: 447, 242, 513, 231 ActionDest: 14 Page: Label: 711 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 180, 705, 211, 693 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 694, 95, 682 ActionDest: 14 Annotation: Subtype: Link Rect: 59, 640, 121, 628 ActionDest: 14 Annotation: Subtype: Link Rect: 113, 629, 180, 618 ActionDest: 12 Annotation: Subtype: Link Rect: 121, 597, 194, 585 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 586, 200, 575 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 576, 74, 564 ActionDest: 14 Annotation: Subtype: Link Rect: 114, 511, 182, 499 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 500, 197, 489 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 490, 195, 478 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 479, 192, 467 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 468, 87, 456 ActionDest: 12 Annotation: Subtype: Link Rect: 165, 468, 194, 456 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 457, 100, 446 ActionDest: 14 Annotation: Subtype: Link Rect: 96, 361, 192, 349 ActionDest: 14 Annotation: Subtype: Link Rect: 92, 328, 182, 317 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 318, 132, 306 ActionDest: 14 Annotation: Subtype: Link Rect: 130, 210, 197, 198 ActionDest: 12 Annotation: Subtype: Link Rect: 106, 135, 199, 123 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 124, 141, 112 ActionDest: 12 Annotation: Subtype: Link Rect: 79, 113, 205, 102 ActionDest: 12 Annotation: Subtype: Link Rect: 56, 103, 97, 91 ActionDest: 12 Annotation: Subtype: Link Rect: 290, 705, 360, 693 ActionDest: 14 Annotation: Subtype: Link Rect: 307, 672, 383, 661 ActionDest: 14 Annotation: Subtype: Link Rect: 226, 662, 347, 650 ActionDest: 14 Annotation: Subtype: Link Rect: 229, 543, 302, 532 ActionDest: 12 Annotation: Subtype: Link Rect: 274, 468, 336, 456 ActionDest: 14 Annotation: Subtype: Link Rect: 339, 457, 365, 446 ActionDest: 14 Annotation: Subtype: Link Rect: 226, 447, 269, 435 ActionDest: 14 Annotation: Subtype: Link Rect: 271, 328, 362, 317 ActionDest: 12 Annotation: Subtype: Link Rect: 348, 264, 377, 252 ActionDest: 12 Annotation: Subtype: Link Rect: 226, 253, 269, 241 ActionDest: 12 Annotation: Subtype: Link Rect: 229, 221, 377, 209 ActionDest: 12 Annotation: Subtype: Link Rect: 226, 210, 366, 198 ActionDest: 12 Annotation: Subtype: Link Rect: 226, 199, 243, 188 ActionDest: 12 Annotation: Subtype: Link Rect: 332, 167, 370, 155 ActionDest: 12 Annotation: Subtype: Link Rect: 226, 156, 269, 145 ActionDest: 12 Annotation: Subtype: Link Rect: 462, 726, 535, 714 ActionDest: 12 Annotation: Subtype: Link Rect: 438, 672, 511, 661 ActionDest: 12 Annotation: Subtype: Link Rect: 507, 597, 542, 585 ActionDest: 12 Annotation: Subtype: Link Rect: 396, 586, 435, 575 ActionDest: 12 Annotation: Subtype: Link Rect: 399, 543, 483, 532 ActionDest: 12 Annotation: Subtype: Link Rect: 508, 500, 548, 489 ActionDest: 14 Annotation: Subtype: Link Rect: 396, 490, 436, 478 ActionDest: 14 Annotation: Subtype: Link Rect: 524, 490, 552, 478 ActionDest: 14 Annotation: Subtype: Link Rect: 396, 479, 436, 467 ActionDest: 14 Annotation: Subtype: Link Rect: 399, 296, 466, 284 ActionDest: 14 Page: Label: 712 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 45, 715, 179, 704 ActionDest: 12 Annotation: Subtype: Link Rect: 45, 640, 107, 628 ActionDest: 14 Annotation: Subtype: Link Rect: 94, 479, 162, 467 ActionDest: 14 Annotation: Subtype: Link Rect: 91, 393, 160, 381 ActionDest: 14 Annotation: Subtype: Link Rect: 133, 371, 185, 360 ActionDest: 12 Annotation: Subtype: Link Rect: 42, 361, 136, 349 ActionDest: 12 Annotation: Subtype: Link Rect: 314, 726, 365, 714 ActionDest: 12 Annotation: Subtype: Link Rect: 212, 715, 230, 704 ActionDest: 12 Annotation: Subtype: Link Rect: 274, 672, 345, 661 ActionDest: 12 Annotation: Subtype: Link Rect: 234, 533, 317, 521 ActionDest: 12 Annotation: Subtype: Link Rect: 296, 522, 359, 510 ActionDest: 12 Annotation: Subtype: Link Rect: 212, 511, 298, 499 ActionDest: 12 Annotation: Subtype: Link Rect: 338, 156, 365, 145 ActionDest: 14 Annotation: Subtype: Link Rect: 212, 146, 256, 134 ActionDest: 14 Annotation: Subtype: Link Rect: 313, 70, 363, 59 ActionDest: 12 Annotation: Subtype: Link Rect: 212, 60, 229, 48 ActionDest: 12 Annotation: Subtype: Link Rect: 477, 672, 536, 661 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 662, 424, 650 ActionDest: 14 Annotation: Subtype: Link Rect: 385, 629, 477, 618 ActionDest: 12 Annotation: Subtype: Link Rect: 501, 576, 538, 564 ActionDest: 14 Annotation: Subtype: Link Rect: 382, 565, 426, 553 ActionDest: 14 Annotation: Subtype: Link Rect: 385, 533, 463, 521 ActionDest: 14 Annotation: Subtype: Link Rect: 418, 404, 490, 392 ActionDest: 14 Annotation: Subtype: Link Rect: 431, 296, 521, 284 ActionDest: 12 Annotation: Subtype: Link Rect: 382, 285, 464, 274 ActionDest: 12 Annotation: Subtype: Link Rect: 410, 167, 476, 155 ActionDest: 12 Page: Label: 713 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 161, 608, 187, 596 ActionDest: 14 Annotation: Subtype: Link Rect: 56, 597, 97, 585 ActionDest: 14 Annotation: Subtype: Link Rect: 96, 447, 157, 435 ActionDest: 14 Annotation: Subtype: Link Rect: 106, 307, 175, 295 ActionDest: 12 Annotation: Subtype: Link Rect: 59, 264, 151, 252 ActionDest: 12 Annotation: Subtype: Link Rect: 59, 242, 120, 231 ActionDest: 12 Annotation: Subtype: Link Rect: 125, 232, 195, 220 ActionDest: 12 Annotation: Subtype: Link Rect: 59, 189, 138, 177 ActionDest: 12 Annotation: Subtype: Link Rect: 229, 640, 337, 628 ActionDest: 12 Annotation: Subtype: Link Rect: 229, 576, 308, 564 ActionDest: 14 Annotation: Subtype: Link Rect: 256, 522, 324, 510 ActionDest: 14 Annotation: Subtype: Link Rect: 229, 447, 351, 435 ActionDest: 14 Annotation: Subtype: Link Rect: 226, 436, 327, 424 ActionDest: 14 Annotation: Subtype: Link Rect: 229, 264, 303, 252 ActionDest: 12 Annotation: Subtype: Link Rect: 229, 242, 324, 231 ActionDest: 12 Annotation: Subtype: Link Rect: 334, 156, 360, 145 ActionDest: 14 Annotation: Subtype: Link Rect: 226, 146, 307, 134 ActionDest: 14 Annotation: Subtype: Link Rect: 295, 135, 374, 123 ActionDest: 14 Annotation: Subtype: Link Rect: 508, 715, 536, 704 ActionDest: 12 Annotation: Subtype: Link Rect: 396, 705, 518, 693 ActionDest: 12 Annotation: Subtype: Link Rect: 504, 619, 527, 607 ActionDest: 14 Annotation: Subtype: Link Rect: 396, 608, 454, 596 ActionDest: 14 Page: Label: 714 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 42, 702, 198, 693 Annotation: Subtype: Link Rect: 51, 694, 194, 684 Annotation: Subtype: Link Rect: 51, 685, 169, 675 Annotation: Subtype: Link Rect: 51, 676, 195, 666 Annotation: Subtype: Link Rect: 51, 666, 160, 657 Annotation: Subtype: Link Rect: 42, 658, 163, 648 Annotation: Subtype: Link Rect: 51, 649, 187, 639 Annotation: Subtype: Link Rect: 51, 640, 192, 630 Annotation: Subtype: Link Rect: 51, 631, 190, 621 Annotation: Subtype: Link Rect: 51, 622, 197, 612 Annotation: Subtype: Link Rect: 51, 613, 175, 603 Annotation: Subtype: Link Rect: 42, 603, 198, 594 Annotation: Subtype: Link Rect: 51, 595, 196, 585 Annotation: Subtype: Link Rect: 51, 586, 184, 576 Annotation: Subtype: Link Rect: 51, 577, 184, 567 Annotation: Subtype: Link Rect: 51, 568, 198, 558 Annotation: Subtype: Link Rect: 51, 558, 155, 549 Annotation: Subtype: Link Rect: 42, 549, 185, 540 Annotation: Subtype: Link Rect: 51, 541, 186, 531 Annotation: Subtype: Link Rect: 51, 532, 190, 522 Annotation: Subtype: Link Rect: 51, 523, 198, 513 Annotation: Subtype: Link Rect: 51, 514, 189, 504 Annotation: Subtype: Link Rect: 51, 505, 198, 495 Annotation: Subtype: Link Rect: 51, 495, 123, 486 Annotation: Subtype: Link Rect: 42, 486, 190, 477 Annotation: Subtype: Link Rect: 51, 478, 194, 468 Annotation: Subtype: Link Rect: 51, 469, 198, 459 Annotation: Subtype: Link Rect: 51, 460, 194, 450 Annotation: Subtype: Link Rect: 51, 450, 188, 441 Annotation: Subtype: Link Rect: 42, 441, 183, 432 Annotation: Subtype: Link Rect: 51, 433, 166, 423 Annotation: Subtype: Link Rect: 51, 424, 183, 414 Annotation: Subtype: Link Rect: 51, 415, 196, 405 Annotation: Subtype: Link Rect: 51, 406, 192, 396 Annotation: Subtype: Link Rect: 51, 396, 112, 387 Annotation: Subtype: Link Rect: 42, 387, 178, 378 Annotation: Subtype: Link Rect: 51, 378, 186, 369 Annotation: Subtype: Link Rect: 51, 370, 192, 360 Annotation: Subtype: Link Rect: 51, 361, 196, 351 Annotation: Subtype: Link Rect: 51, 352, 198, 342 Annotation: Subtype: Link Rect: 51, 342, 166, 333 Annotation: Subtype: Link Rect: 42, 334, 196, 324 Annotation: Subtype: Link Rect: 51, 325, 195, 315 Annotation: Subtype: Link Rect: 51, 316, 188, 306 Annotation: Subtype: Link Rect: 51, 306, 95, 297 Annotation: Subtype: Link Rect: 42, 297, 188, 288 Annotation: Subtype: Link Rect: 51, 289, 187, 279 Annotation: Subtype: Link Rect: 51, 280, 176, 270 Annotation: Subtype: Link Rect: 51, 271, 187, 261 Annotation: Subtype: Link Rect: 51, 262, 198, 252 Annotation: Subtype: Link Rect: 51, 252, 104, 243 Annotation: Subtype: Link Rect: 42, 243, 192, 234 Annotation: Subtype: Link Rect: 51, 235, 189, 225 Annotation: Subtype: Link Rect: 51, 226, 183, 216 Annotation: Subtype: Link Rect: 51, 217, 179, 207 Annotation: Subtype: Link Rect: 51, 208, 196, 198 Annotation: Subtype: Link Rect: 42, 198, 192, 189 Annotation: Subtype: Link Rect: 51, 189, 193, 180 Annotation: Subtype: Link Rect: 51, 181, 194, 171 Annotation: Subtype: Link Rect: 51, 172, 187, 162 Annotation: Subtype: Link Rect: 51, 163, 197, 153 Annotation: Subtype: Link Rect: 51, 153, 76, 144 Annotation: Subtype: Link Rect: 42, 144, 198, 135 Annotation: Subtype: Link Rect: 51, 136, 190, 126 Annotation: Subtype: Link Rect: 51, 127, 198, 117 Annotation: Subtype: Link Rect: 51, 118, 185, 108 Annotation: Subtype: Link Rect: 51, 109, 187, 99 Annotation: Subtype: Link Rect: 51, 100, 197, 90 Annotation: Subtype: Link Rect: 51, 90, 106, 81 Annotation: Subtype: Link Rect: 42, 82, 183, 72 Annotation: Subtype: Link Rect: 51, 73, 198, 63 Annotation: Subtype: Link Rect: 51, 64, 198, 54 Annotation: Subtype: Link Rect: 221, 726, 352, 716 Annotation: Subtype: Link Rect: 221, 717, 346, 707 Annotation: Subtype: Link Rect: 212, 708, 342, 698 Annotation: Subtype: Link Rect: 221, 699, 355, 689 Annotation: Subtype: Link Rect: 221, 690, 246, 680 Annotation: Subtype: Link Rect: 212, 681, 362, 671 Annotation: Subtype: Link Rect: 221, 672, 362, 662 Annotation: Subtype: Link Rect: 221, 663, 367, 653 Annotation: Subtype: Link Rect: 221, 654, 366, 644 Annotation: Subtype: Link Rect: 221, 645, 331, 635 Annotation: Subtype: Link Rect: 212, 636, 351, 626 Annotation: Subtype: Link Rect: 221, 627, 346, 617 Annotation: Subtype: Link Rect: 221, 618, 358, 608 Annotation: Subtype: Link Rect: 221, 609, 365, 599 Annotation: Subtype: Link Rect: 221, 600, 274, 590 Annotation: Subtype: Link Rect: 212, 591, 358, 581 Annotation: Subtype: Link Rect: 221, 582, 359, 572 Annotation: Subtype: Link Rect: 221, 573, 363, 563 Annotation: Subtype: Link Rect: 221, 564, 368, 554 Annotation: Subtype: Link Rect: 221, 555, 318, 545 Annotation: Subtype: Link Rect: 212, 546, 342, 536 Annotation: Subtype: Link Rect: 221, 537, 349, 527 Annotation: Subtype: Link Rect: 221, 528, 362, 518 Annotation: Subtype: Link Rect: 221, 519, 258, 509 Annotation: Subtype: Link Rect: 212, 510, 344, 500 Annotation: Subtype: Link Rect: 221, 501, 343, 491 Annotation: Subtype: Link Rect: 221, 492, 361, 482 Annotation: Subtype: Link Rect: 221, 483, 330, 473 Annotation: Subtype: Link Rect: 212, 474, 345, 464 Annotation: Subtype: Link Rect: 221, 465, 361, 455 Annotation: Subtype: Link Rect: 221, 456, 359, 446 Annotation: Subtype: Link Rect: 221, 447, 360, 437 Annotation: Subtype: Link Rect: 221, 438, 352, 428 Annotation: Subtype: Link Rect: 212, 429, 362, 419 Annotation: Subtype: Link Rect: 221, 420, 363, 410 Annotation: Subtype: Link Rect: 221, 411, 357, 401 Annotation: Subtype: Link Rect: 221, 402, 331, 392 Annotation: Subtype: Link Rect: 212, 393, 352, 383 Annotation: Subtype: Link Rect: 221, 384, 365, 374 Annotation: Subtype: Link Rect: 221, 375, 364, 365 Annotation: Subtype: Link Rect: 221, 366, 368, 356 Annotation: Subtype: Link Rect: 221, 357, 348, 347 Annotation: Subtype: Link Rect: 221, 348, 246, 338 Annotation: Subtype: Link Rect: 212, 339, 365, 329 Annotation: Subtype: Link Rect: 221, 330, 361, 320 Annotation: Subtype: Link Rect: 221, 321, 365, 311 Annotation: Subtype: Link Rect: 221, 312, 365, 302 Annotation: Subtype: Link Rect: 221, 303, 363, 293 Annotation: Subtype: Link Rect: 221, 294, 322, 284 Annotation: Subtype: Link Rect: 212, 285, 362, 275 Annotation: Subtype: Link Rect: 221, 276, 360, 266 Annotation: Subtype: Link Rect: 221, 267, 361, 257 Annotation: Subtype: Link Rect: 221, 258, 368, 248 Annotation: Subtype: Link Rect: 221, 249, 250, 239 Annotation: Subtype: Link Rect: 212, 240, 358, 230 Annotation: Subtype: Link Rect: 221, 231, 353, 221 Annotation: Subtype: Link Rect: 221, 222, 360, 212 Annotation: Subtype: Link Rect: 221, 213, 357, 203 Annotation: Subtype: Link Rect: 221, 204, 345, 194 Annotation: Subtype: Link Rect: 221, 195, 353, 185 Annotation: Subtype: Link Rect: 221, 186, 339, 176 Annotation: Subtype: Link Rect: 212, 177, 357, 167 Annotation: Subtype: Link Rect: 221, 168, 343, 158 Annotation: Subtype: Link Rect: 221, 159, 350, 149 Annotation: Subtype: Link Rect: 221, 150, 345, 140 Annotation: Subtype: Link Rect: 221, 141, 246, 131 Annotation: Subtype: Link Rect: 212, 132, 356, 122 Annotation: Subtype: Link Rect: 221, 123, 338, 113 Annotation: Subtype: Link Rect: 221, 114, 356, 104 Annotation: Subtype: Link Rect: 221, 105, 244, 95 Annotation: Subtype: Link Rect: 212, 96, 363, 86 Annotation: Subtype: Link Rect: 221, 87, 356, 77 Annotation: Subtype: Link Rect: 221, 78, 300, 68 Annotation: Subtype: Link Rect: 212, 69, 327, 59 Annotation: Subtype: Link Rect: 221, 60, 359, 50 Annotation: Subtype: Link Rect: 391, 726, 518, 716 Annotation: Subtype: Link Rect: 391, 717, 528, 707 Annotation: Subtype: Link Rect: 382, 708, 520, 698 Annotation: Subtype: Link Rect: 391, 699, 532, 689 Annotation: Subtype: Link Rect: 391, 690, 536, 680 Annotation: Subtype: Link Rect: 391, 681, 455, 671 Annotation: Subtype: Link Rect: 382, 672, 535, 662 Annotation: Subtype: Link Rect: 391, 663, 516, 653 Annotation: Subtype: Link Rect: 391, 654, 489, 644 Annotation: Subtype: Link Rect: 382, 645, 527, 635 Annotation: Subtype: Link Rect: 391, 636, 518, 626 Annotation: Subtype: Link Rect: 391, 627, 530, 617 Annotation: Subtype: Link Rect: 391, 618, 523, 608 Annotation: Subtype: Link Rect: 391, 609, 446, 599 Annotation: Subtype: Link Rect: 382, 600, 523, 590 Annotation: Subtype: Link Rect: 391, 591, 523, 581 Annotation: Subtype: Link Rect: 391, 582, 521, 572 Annotation: Subtype: Link Rect: 391, 573, 535, 563 Annotation: Subtype: Link Rect: 391, 564, 437, 554 Annotation: Subtype: Link Rect: 382, 555, 533, 545 Annotation: Subtype: Link Rect: 391, 546, 538, 536 Annotation: Subtype: Link Rect: 391, 537, 520, 527 Annotation: Subtype: Link Rect: 391, 528, 530, 518 Annotation: Subtype: Link Rect: 382, 519, 524, 509 Annotation: Subtype: Link Rect: 391, 510, 512, 500 Annotation: Subtype: Link Rect: 391, 501, 518, 491 Annotation: Subtype: Link Rect: 391, 492, 538, 482 Annotation: Subtype: Link Rect: 391, 483, 532, 473 Annotation: Subtype: Link Rect: 391, 474, 534, 464 Annotation: Subtype: Link Rect: 391, 465, 448, 455 Annotation: Subtype: Link Rect: 382, 456, 531, 446 Annotation: Subtype: Link Rect: 391, 447, 522, 437 Annotation: Subtype: Link Rect: 391, 438, 529, 428 Annotation: Subtype: Link Rect: 391, 429, 533, 419 Annotation: Subtype: Link Rect: 391, 420, 516, 410 Annotation: Subtype: Link Rect: 391, 411, 471, 401 Annotation: Subtype: Link Rect: 382, 402, 508, 392 Annotation: Subtype: Link Rect: 391, 393, 504, 383 Annotation: Subtype: Link Rect: 391, 384, 536, 374 Annotation: Subtype: Link Rect: 391, 375, 534, 365 Annotation: Subtype: Link Rect: 391, 366, 527, 356 Annotation: Subtype: Link Rect: 391, 357, 424, 347 Annotation: Subtype: Link Rect: 382, 348, 526, 338 Annotation: Subtype: Link Rect: 391, 339, 523, 329 Annotation: Subtype: Link Rect: 391, 330, 521, 320 Annotation: Subtype: Link Rect: 391, 321, 438, 311 Annotation: Subtype: Link Rect: 382, 312, 525, 302 Annotation: Subtype: Link Rect: 391, 303, 514, 293 Annotation: Subtype: Link Rect: 391, 294, 534, 284 Annotation: Subtype: Link Rect: 391, 285, 506, 275 Annotation: Subtype: Link Rect: 382, 276, 519, 266 Annotation: Subtype: Link Rect: 391, 267, 532, 257 Annotation: Subtype: Link Rect: 391, 258, 531, 248 Annotation: Subtype: Link Rect: 391, 249, 525, 239 Annotation: Subtype: Link Rect: 391, 240, 514, 230 Annotation: Subtype: Link Rect: 391, 231, 479, 221 Annotation: Subtype: Link Rect: 382, 222, 536, 212 Annotation: Subtype: Link Rect: 391, 213, 538, 203 Annotation: Subtype: Link Rect: 391, 204, 529, 194 Annotation: Subtype: Link Rect: 391, 195, 529, 185 Annotation: Subtype: Link Rect: 391, 186, 526, 176 Annotation: Subtype: Link Rect: 391, 177, 516, 167 Annotation: Subtype: Link Rect: 382, 168, 519, 158 Annotation: Subtype: Link Rect: 391, 159, 535, 149 Annotation: Subtype: Link Rect: 391, 150, 523, 140 Annotation: Subtype: Link Rect: 391, 141, 529, 131 Annotation: Subtype: Link Rect: 391, 132, 536, 122 Annotation: Subtype: Link Rect: 391, 123, 531, 113 Annotation: Subtype: Link Rect: 391, 114, 530, 104 Annotation: Subtype: Link Rect: 391, 105, 518, 95 Annotation: Subtype: Link Rect: 391, 96, 417, 86 Annotation: Subtype: Link Rect: 382, 87, 526, 77 Annotation: Subtype: Link Rect: 391, 78, 526, 68 Annotation: Subtype: Link Rect: 391, 69, 531, 59 Annotation: Subtype: Link Rect: 391, 60, 486, 50 Page: Label: 715 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 56, 726, 192, 716 Annotation: Subtype: Link Rect: 65, 717, 206, 707 Annotation: Subtype: Link Rect: 65, 708, 209, 698 Annotation: Subtype: Link Rect: 65, 699, 207, 689 Annotation: Subtype: Link Rect: 65, 690, 167, 680 Annotation: Subtype: Link Rect: 56, 681, 188, 671 Annotation: Subtype: Link Rect: 65, 672, 209, 662 Annotation: Subtype: Link Rect: 65, 663, 199, 653 Annotation: Subtype: Link Rect: 65, 654, 162, 644 Annotation: Subtype: Link Rect: 56, 645, 197, 635 Annotation: Subtype: Link Rect: 65, 636, 211, 626 Annotation: Subtype: Link Rect: 65, 627, 212, 617 Annotation: Subtype: Link Rect: 65, 618, 203, 608 Annotation: Subtype: Link Rect: 65, 609, 145, 599 Annotation: Subtype: Link Rect: 56, 600, 211, 590 Annotation: Subtype: Link Rect: 65, 591, 212, 581 Annotation: Subtype: Link Rect: 65, 582, 212, 572 Annotation: Subtype: Link Rect: 65, 573, 180, 563 Annotation: Subtype: Link Rect: 56, 564, 204, 554 Annotation: Subtype: Link Rect: 65, 555, 192, 545 Annotation: Subtype: Link Rect: 65, 546, 151, 536 Annotation: Subtype: Link Rect: 56, 537, 186, 527 Annotation: Subtype: Link Rect: 65, 528, 197, 518 Annotation: Subtype: Link Rect: 65, 519, 202, 509 Annotation: Subtype: Link Rect: 65, 510, 204, 500 Annotation: Subtype: Link Rect: 65, 501, 192, 491 Annotation: Subtype: Link Rect: 65, 492, 194, 482 Annotation: Subtype: Link Rect: 65, 483, 129, 473 Annotation: Subtype: Link Rect: 65, 456, 190, 446 Annotation: Subtype: Link Rect: 65, 447, 153, 437 Annotation: Subtype: Link Rect: 56, 438, 184, 428 Annotation: Subtype: Link Rect: 65, 429, 202, 419 Annotation: Subtype: Link Rect: 65, 420, 204, 410 Annotation: Subtype: Link Rect: 65, 411, 206, 401 Annotation: Subtype: Link Rect: 65, 402, 183, 392 Annotation: Subtype: Link Rect: 65, 393, 137, 383 Annotation: Subtype: Link Rect: 56, 384, 211, 374 Annotation: Subtype: Link Rect: 65, 375, 209, 365 Annotation: Subtype: Link Rect: 65, 366, 204, 356 Annotation: Subtype: Link Rect: 65, 357, 142, 347 Annotation: Subtype: Link Rect: 56, 348, 212, 338 Annotation: Subtype: Link Rect: 65, 339, 197, 329 Annotation: Subtype: Link Rect: 65, 330, 194, 320 Annotation: Subtype: Link Rect: 65, 321, 149, 311 Annotation: Subtype: Link Rect: 56, 312, 203, 302 Annotation: Subtype: Link Rect: 65, 303, 197, 293 Annotation: Subtype: Link Rect: 65, 294, 193, 284 Annotation: Subtype: Link Rect: 235, 726, 375, 716 Annotation: Subtype: Link Rect: 235, 717, 262, 707 Annotation: Subtype: Link Rect: 226, 708, 348, 698 Annotation: Subtype: Link Rect: 235, 699, 373, 689 Annotation: Subtype: Link Rect: 235, 690, 378, 680 Annotation: Subtype: Link Rect: 235, 681, 272, 671 Annotation: Subtype: Link Rect: 226, 672, 369, 662 Annotation: Subtype: Link Rect: 235, 663, 374, 653 Annotation: Subtype: Link Rect: 235, 654, 381, 644 Annotation: Subtype: Link Rect: 235, 645, 374, 635 Annotation: Subtype: Link Rect: 235, 636, 354, 626 Annotation: Subtype: Link Rect: 226, 627, 372, 617 Annotation: Subtype: Link Rect: 235, 618, 372, 608 Annotation: Subtype: Link Rect: 235, 609, 364, 599 Annotation: Subtype: Link Rect: 226, 600, 371, 590 Annotation: Subtype: Link Rect: 235, 591, 379, 581 Annotation: Subtype: Link Rect: 235, 582, 369, 572 Annotation: Subtype: Link Rect: 235, 573, 379, 563 Annotation: Subtype: Link Rect: 235, 564, 257, 554 Annotation: Subtype: Link Rect: 226, 555, 377, 545 Annotation: Subtype: Link Rect: 235, 546, 380, 536 Annotation: Subtype: Link Rect: 235, 537, 365, 527 Annotation: Subtype: Link Rect: 235, 528, 321, 518 Annotation: Subtype: Link Rect: 226, 519, 365, 509 Annotation: Subtype: Link Rect: 235, 510, 370, 500 Annotation: Subtype: Link Rect: 235, 501, 369, 491 Annotation: Subtype: Link Rect: 235, 492, 370, 482 Annotation: Subtype: Link Rect: 235, 483, 383, 473 Annotation: Subtype: Link Rect: 235, 474, 269, 464 Annotation: Subtype: Link Rect: 226, 465, 368, 455 Annotation: Subtype: Link Rect: 235, 456, 375, 446 Annotation: Subtype: Link Rect: 235, 447, 358, 437 Annotation: Subtype: Link Rect: 235, 438, 369, 428 Annotation: Subtype: Link Rect: 235, 429, 375, 419 Annotation: Subtype: Link Rect: 235, 420, 291, 410 Annotation: Subtype: Link Rect: 226, 411, 372, 401 Annotation: Subtype: Link Rect: 235, 402, 376, 392 Annotation: Subtype: Link Rect: 235, 393, 360, 383 Annotation: Subtype: Link Rect: 235, 384, 339, 374 Annotation: Subtype: Link Rect: 226, 375, 361, 365 Annotation: Subtype: Link Rect: 235, 366, 375, 356 Annotation: Subtype: Link Rect: 235, 357, 354, 347 Annotation: Subtype: Link Rect: 235, 348, 371, 338 Annotation: Subtype: Link Rect: 235, 339, 277, 329 Annotation: Subtype: Link Rect: 226, 330, 364, 320 Annotation: Subtype: Link Rect: 235, 321, 379, 311 Annotation: Subtype: Link Rect: 235, 312, 381, 302 Annotation: Subtype: Link Rect: 235, 303, 365, 293 Annotation: Subtype: Link Rect: 235, 294, 382, 284 Annotation: Subtype: Link Rect: 405, 726, 544, 716 Annotation: Subtype: Link Rect: 405, 717, 455, 707 Annotation: Subtype: Link Rect: 396, 708, 537, 698 Annotation: Subtype: Link Rect: 405, 699, 552, 689 Annotation: Subtype: Link Rect: 405, 690, 537, 680 Annotation: Subtype: Link Rect: 405, 681, 484, 671 Annotation: Subtype: Link Rect: 396, 672, 537, 662 Annotation: Subtype: Link Rect: 405, 663, 489, 653 Annotation: Subtype: Link Rect: 396, 654, 533, 644 Annotation: Subtype: Link Rect: 405, 645, 552, 635 Annotation: Subtype: Link Rect: 405, 636, 529, 626 Annotation: Subtype: Link Rect: 405, 627, 535, 617 Annotation: Subtype: Link Rect: 405, 618, 535, 608 Annotation: Subtype: Link Rect: 396, 609, 545, 599 Annotation: Subtype: Link Rect: 405, 600, 551, 590 Annotation: Subtype: Link Rect: 405, 591, 543, 581 Annotation: Subtype: Link Rect: 405, 582, 518, 572 Annotation: Subtype: Link Rect: 396, 573, 548, 563 Annotation: Subtype: Link Rect: 405, 564, 530, 554 Annotation: Subtype: Link Rect: 405, 555, 538, 545 Annotation: Subtype: Link Rect: 405, 546, 423, 536 Annotation: Subtype: Link Rect: 396, 537, 538, 527 Annotation: Subtype: Link Rect: 405, 528, 533, 518 Annotation: Subtype: Link Rect: 405, 519, 539, 509 Annotation: Subtype: Link Rect: 405, 510, 540, 500 Annotation: Subtype: Link Rect: 405, 501, 541, 491 Annotation: Subtype: Link Rect: 405, 492, 432, 482 Annotation: Subtype: Link Rect: 396, 483, 527, 473 Annotation: Subtype: Link Rect: 405, 474, 537, 464 Annotation: Subtype: Link Rect: 405, 465, 547, 455 Annotation: Subtype: Link Rect: 405, 456, 458, 446 Annotation: Subtype: Link Rect: 396, 447, 520, 437 Annotation: Subtype: Link Rect: 405, 438, 549, 428 Annotation: Subtype: Link Rect: 405, 429, 534, 419 Annotation: Subtype: Link Rect: 405, 420, 538, 410 Annotation: Subtype: Link Rect: 405, 411, 553, 401 Annotation: Subtype: Link Rect: 405, 402, 510, 392 Annotation: Subtype: Link Rect: 396, 393, 537, 383 Annotation: Subtype: Link Rect: 405, 384, 533, 374 Annotation: Subtype: Link Rect: 405, 375, 520, 365 Annotation: Subtype: Link Rect: 405, 366, 543, 356 Annotation: Subtype: Link Rect: 405, 357, 485, 347 Annotation: Subtype: Link Rect: 396, 348, 543, 338 Annotation: Subtype: Link Rect: 405, 339, 552, 329 Annotation: Subtype: Link Rect: 405, 330, 546, 320 Annotation: Subtype: Link Rect: 405, 321, 483, 311 Checksum: 3e4aac9c Type: CRC32 Checksum: 54b39cffd78fc9e16d7635d1d259f988 Type: MD5 Checksum: f4b8e82049321ea3052440f2dba3774485a86391 Type: SHA-1 Checksum: 73c489827a81961012bda20e92ac98bb636936acd35da0981b136ab1da1419ae Type: SHA-256