152ba95dae0888e51effb5d62dc25af4  pmc_29987762.pdf
ea462d3bfb272a8b909e52c304e330cf9a249b98  pmc_29987762.pdf
b864ca1d4a205fbd1affc006d4ad72f71f7098141a23bbc5a72f57cf7f564e3c  pmc_29987762.pdf

Title:          Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death
Subject:        Neurotherapeutics, doi:10.1007/s13311-018-0646-z
Keywords:       Candesartan,Microglia,Neurodegeneration,Parkinson,Telmisartan,Viral vectors
Author:         Ana I. Rodriguez-Perez
Creator:        Arbortext Advanced Print Publisher 9.1.440/W Unicode
Producer:       Acrobat Distiller 9.0.0 (Windows)
CreationDate:   Mon Nov 19 14:11:52 2018 CET
ModDate:        Wed Nov 21 21:22:12 2018 CET
Tagged:         no
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Pages:          19
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PDF version:    1.4

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        Title: Introduction
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        Title: Materials and Methods
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          Title: Experimental Design
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          Title: Synthesis and Purification of Adeno-Associated Vectors
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          Title: Stereotaxic Injections and Candesartan and Telmisartan Administration
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          Title: Double/Triple Immunofluorescence and Laser Confocal Microscopy
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          Title: Western Blot
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          Title: Immunohistochemistry, Nissl Staining, and Stereological Analysis
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          Title: High Performance Liquid Chromatography
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          Title: Motor Behavioral Analysis: Cylinder Test, Rotarod Test, and Locomotor Activity
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         Item: 
          Title: RNA Extraction and Real-Time Quantitative Reverse Transcriptase–Polymerase Chain Reaction
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         Item: 
          Title: TNF-α Quantification
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          Title: NADPH Oxidase Activity
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          Title: Statistical Analysis
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        Title: Results
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         Item: 
          Title: Transgene Expression Following AAV Vector Injection
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         Item: 
          Title: Loss of Dopaminergic Neurons After Overexpression of WT or Mutated A53T Alpha-Synuclein: Effect of AT1 Receptor Blockers
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          Title: HPLC Analysis and Motor Behavior
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         Item: 
          Title: Microglial Response After Overexpression of WT or Mutated A53T Αlpha-Synuclein: Effect of AT1 Receptor Blockers
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        Title: Discussion
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        Title: References
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     Item: 
      Title: Introduction
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      Title: Materials and Methods
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      Title: Results
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      Title: Discussion
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      Title: References
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   Info: 
    Title: Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death
    Author: Ana I. Rodriguez-Perez
    Subject: Neurotherapeutics, doi:10.1007/s13311-018-0646-z
    Keywords: Candesartan,Microglia,Neurodegeneration,Parkinson,Telmisartan,Viral vectors
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