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Producer: Aspose.Pdf for .NET 10.1.0; modified using iTextSharp™ 5.4.0 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sun Sep 2 09:36:48 2018 CEST ModDate: Sun Sep 16 13:25:06 2018 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 600.05 x 800 pts Page rot: 0 File size: 952125 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MinionPro-Regular CID Type 0C Identity-H yes no yes 670 0 CDMFGD+MinionPro-It Type 1C Custom yes yes yes 35 0 CDMFGE+minionblackit Type 1C WinAnsi yes yes no 671 0 CDMFGF+Minion-Black Type 1C WinAnsi yes yes no 36 0 CDMFJE+MinionPro-Regular2 Type 1C Custom yes yes yes 34 0 OGTZPO+MinionPro-Regular CID TrueType Identity-H yes yes yes 1 0 CDMFLF+MinionMath-Regular Type 1C WinAnsi yes yes no 37 0 MinionPro-Regular3 Type 1C Custom yes no yes 123 0 CDMGMA+MinionPro-Bold Type 1C Custom yes yes yes 134 0 CDMHAA+MinionMath-Capt Type 1C Custom yes yes yes 332 0 MinionPro-Bold2 Type 1C Custom yes no yes 450 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-05-04 02:33:01 CEST RepresentationInformation: pmc_30246022.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-02-05 11:41:18 CET Size: 952125 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: ISO PDF/A-1, Level B PDFMetadata: Objects: 693 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Info: Title: 5456074.dvi Keywords: Creator: Aspose Ltd. Producer: Aspose.Pdf for .NET 10.1.0; modified using iTextSharp™ 5.4.0 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sun Sep 02 09:36:48 CEST 2018 ModDate: Sun Sep 16 13:25:06 CEST 2018 ID: 0x9d72ed7bd6b75b7537410f4c6325a19e, 0x108b2b044d9efecc7d7f25a599ac1942 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png CompressionScheme: uncompressed ImageWidth: 1 ImageHeight: 1 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Image: NisoImageMetadata: FormatName: image/png CompressionScheme: uncompressed ImageWidth: 1 ImageHeight: 1 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Image: NisoImageMetadata: FormatName: image/png CompressionScheme: uncompressed ImageWidth: 1 ImageHeight: 1 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Image: NisoImageMetadata: FormatName: image/png CompressionScheme: uncompressed ImageWidth: 1 ImageHeight: 1 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Fonts: Type0: Font: BaseFont: OGTZPO+MinionPro-Regular Encoding: Identity-H ToUnicode: true Font: BaseFont: MinionPro-Regular Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: CDMFJE+MinionPro-Regular2 FontSubset: true FirstChar: 2 LastChar: 249 FontDescriptor: FontName: CDMFJE+MinionPro-Regular2 Flags: Serif, Symbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionPro-Bold2 FirstChar: 2 LastChar: 121 FontDescriptor: FontName: MinionPro-Bold2 Flags: Symbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CDMFGD+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 181 FontDescriptor: FontName: CDMFGD+MinionPro-It Flags: Serif, Symbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CDMFGF+Minion-Black FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: CDMFGF+Minion-Black Flags: Serif, Nonsymbolic, ForceBold FontBBox: -133, -250, 1120, 827 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CDMFLF+MinionMath-Regular FontSubset: true FirstChar: 32 LastChar: 62 FontDescriptor: FontName: CDMFLF+MinionMath-Regular Flags: Nonsymbolic FontBBox: 74, -3, 512, 514 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CDMGMA+MinionPro-Bold FontSubset: true FirstChar: 2 LastChar: 118 FontDescriptor: FontName: CDMGMA+MinionPro-Bold Flags: Symbolic, ForceBold FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionPro-Regular3 FirstChar: 2 LastChar: 146 FontDescriptor: FontName: MinionPro-Regular3 Flags: Symbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CDMHAA+MinionMath-Capt FontSubset: true FirstChar: 2 LastChar: 3 FontDescriptor: FontName: CDMHAA+MinionMath-Capt Flags: Symbolic FontBBox: 124, 53, 486, 470 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CDMFGE+minionblackit FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: CDMFGE+minionblackit Flags: Serif, Nonsymbolic, Italic FontBBox: -192, -258, 1081, 868 FontFile3: true Encoding: WinAnsiEncoding CIDFontType0: Font: BaseFont: MinionPro-Regular CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: MinionPro-Regular Flags: Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true CIDFontType2: Font: BaseFont: OGTZPO+MinionPro-Regular CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: OGTZPO+MinionPro-Regular Flags: Nonsymbolic FontBBox: -289, -360, 1684, 917 FontFile2: true XMP: application/pdfSentinel Amenable Mortality: A New Way to Assess the Quality of Healthcare by Examining Causes of Premature Death for Which Highly Efficacious Medical Interventions Are AvailableVergara-Duarte, MontseBorrell, CarmePérez, GlòriaMartín-Sánchez, Juan CarlosClèries, RamonBuxó, MariaMartínez-Solanas, ÈricaYasui, YutakaMuntaner, CarlesBenach, JoanBackground. Amenable mortality, or premature deaths that could be prevented with medical care, is a proven indicator for assessing healthcare quality when adapted to a country or region’s specific healthcare context. This concept is currently used to evaluate the performance of national and international healthcare systems. However, the levels of efficacy and effectiveness determined using this indicator can vary greatly depending on the causes of death that are included. We introduce a new approach by identifying a subgroup of causes for which there are available treatments with a high level of efficacy. These causes should be considered sentinel events to help identify limitations in the effectiveness and quality of health provision. Methods. We conducted an extensive literature review using a list of amenable causes of death compiled by Spanish researchers. We complemented this approach by assessing the time trends of amenable mortality in two high-income countries that have a similar quality of healthcare but very different systems of provision, namely, Spain and the United States. This enabled us to identify different levels of efficacy of medical interventions (high, medium, and low). We consulted a group of medical experts and combined this information to help make the final classification of sentinel amenable causes of death. Results. Sentinel amenable mortality includes causes such as surgical conditions, thyroid diseases, and asthma. The remaining amenable causes of death either have a higher complexity in terms of the disease or need more effective medical interventions or preventative measures to guarantee early detection and adherence to treatment. These included cardiovascular diseases, diabetes, hypertension, all amenable cancers, and some infectious diseases such as pneumonia, influenza, and tuberculosis. Conclusions. Sentinel amenable mortality could act as a good sentinel indicator to identify major deficiencies in healthcare quality and provision and detect inequalities across populations.BioMed Research InternationalHindawi2018/09/02Research articledoi:10.1155/2018/5456074en Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 206, 534, 220, 546 Flags: Print, NoZoom, NoRotate AppearanceDictionary: true Annotation: Subtype: Link Rect: 50, 713, 168, 721 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 146, 581, 150, 592 Flags: Print, NoZoom, NoRotate AppearanceDictionary: true Destination: 519 Annotation: Subtype: Link Rect: 260, 559, 265, 569 Flags: Print, NoZoom, NoRotate AppearanceDictionary: true Destination: 519 Annotation: Subtype: Link Rect: 167, 513, 173, 524 Flags: Print, NoZoom, NoRotate AppearanceDictionary: true Destination: 519 Annotation: Subtype: Link Rect: 179, 513, 184, 524 Flags: Print, NoZoom, NoRotate AppearanceDictionary: true Destination: 519 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