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Title:          Intravesical Mycobacterium brumae triggers both local and systemic immunotherapeutic responses against bladder cancer in mice
Subject:        Scientific Reports, doi:10.1038/s41598-018-33253-w
Keywords:       
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     Item: 
      Title: Intravesical Mycobacterium brumae triggers both local and systemic immunotherapeutic responses against bladder cancer in mi ...
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Treatment with mycobacteria triggers influx of immune cells into mouse bladders, which was higher when mycobacteria were em ...
         Item: 
          Title: KC, IL-6, MIP-2, MMP-9 and VEGF are present in urine samples from mycobacteria-treated tumor-bearing mice. 
         Item: 
          Title: Mycobacteria treatment induces the production of BCG and M. brumae specific antibodies. 
         Item: 
          Title: Splenocytes from mycobacteria-treated mice specifically proliferate in the presence of the antigens used in the instillatio ...
       Item: 
        Title: Discussion
       Item: 
        Title: Material and Methods
        Children: 
         Item: 
          Title: Bacterial strains and cell line. 
         Item: 
          Title: Orthotopic murine model of BC and intravesical treatment. 
         Item: 
          Title: Detection of infiltrated immune cell subsets in bladders. 
         Item: 
          Title: Detection of macromolecules in urine samples. 
         Item: 
          Title: Detection of anti-mycobacteria antibodies in sera. 
         Item: 
          Title: Proliferation of mycobacteria-stimulated splenocyte cultures. 
         Item: 
          Title: Statistical analysis. 
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Figure 1 Infiltrated immune cells into mycobacteria-treated and non-treated tumor bearing mice 29 days after tumor induction.
       Item: 
        Title: Figure 2 Representative histological images of bladder sections stained with two immunological markers.
       Item: 
        Title: Figure 3 Systemic immune responses in tumor-bearing and healthy mice.
       Item: 
        Title: Figure 4 Schedule of the animal experiments.
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NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
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                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
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