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comb椀渀愀琀椀漀渀 挀栀攀洀漀琀栀攀爀愀瀀礀 昀漀爀 挀漀氀漀爀攀挀琀愀氀 挀愀渀挀攀爩㸾൥湤潢樍㌴㤠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀ㄩ⽆‰⽎數琠㌵㤠〠刯偡牥湴″㐸‰⁒⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㌵〠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䴀ㄩ⽆‰⽐慲敮琠㌴㠠〠刯偲敶″㔱‰⁒⽔楴汥⣾＀䄀䌀䬀一伀圀䰀䔀䐀䜀䴀䔀一吀匩㸾൥湤潢樍㌵ㄠ〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀㠩⽆‰⽎數琠㌵〠〠刯偡牥湴″㐸‰⁒⽐牥瘠㌵㈠〠刯呩瑬攨Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7ce6a65d Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1500955a Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e874448 Children: Item: Title: Outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@29b5cd00 Item: Title: Costs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@60285225 Item: Title: Cost-effectiveness outcome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7113b13f Item: Title: Missing data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@45820e51 Item: Title: Sensitivity analysis Destination: 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randomised phase III trial of two durations of adjuvant Oxaliplatin combination chemotherapy for colorectal cancer José Robles-Zurita Kathleen A. Boyd Andrew H. Briggs Timothy Iveson Rachel S. Kerr Mark P. Saunders Jim Cassidy Niels Henrik Hollander Josep Tabernero Eva Segelov Bengt Glimelius Andrea Harkin Karen Allan John McQueen Sarah Pearson Ashita Waterston Louise Medley Charles Wilson Richard Ellis Sharadah Essapen Amandeep S. Dhadda Rob Hughes Stephen Falk Sherif Raouf Charlotte Rees Rene K Olesen David Propper John Bridgewater Ashraf Azzabi David Farrugia Andrew Webb David Cunningham Tamas Hickish Andrew Weaver Simon Gollins Harpreet S Wasan James Paul Springer US British Journal of Cancer, doi:10.1038/s41416-018-0319-z 10.1038/s41416-018-0319-z http://dx.doi.org/10.1038/s41416-018-0319-z journal British Journal of Cancer © 2018, The Author(s) 1532-1827 10.1038/s41416-018-0319-z springer.com springerlink.com 2010-04-23 True 10.1038/s41416-018-0319-z springer.com springerlink.com Springer 2018-11-27T17:06:12+05:30 2018-11-27T17:05:12+05:30 2018-11-27T17:06:12+05:30 True VoR uuid:8d586687-a259-4e85-8a88-9abba926860a uuid:69371f8f-4043-4e5a-8c88-a4e58627e4aa default 1 converted uuid:550b8883-480f-4939-b06a-a1f80f9bc2b1 converted to PDF/A-2b pdfToolbox 2018-11-27T17:06:12+05:30 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://crossref.org/crossmark/1.0/ crossmark crossmark internal CrossMarkDomains CrossMarkDomains Seq Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Usual same as prism:doi DOI Text external The date when a publication was published. MajorVersionDate Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Copyright copyright Text external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. issn Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url Text http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Label: 1332 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 533, 704, 535, 736 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 533, 709, 553, 740 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 553, 695, 559, 705 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 553, 695, 559, 705 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 65, 259, 68, 268 Flags: Print AppearanceDictionary: true Destination: 85 Annotation: Subtype: Link Rect: 102, 219, 105, 228 Flags: Print AppearanceDictionary: true Destination: 85 Annotation: Subtype: Link Rect: 388, 298, 391, 307 Flags: Print AppearanceDictionary: true Destination: 85 Annotation: Subtype: Link Rect: 476, 749, 548, 757 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 156, 80, 277, 87 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 1333 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 91, 717, 94, 726 Flags: Print AppearanceDictionary: true Destination: 85 Annotation: Subtype: Link Rect: 98, 717, 105, 726 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 266, 717, 273, 726 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 277, 717, 283, 726 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 267, 697, 273, 706 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 697, 282, 706 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 105, 647, 112, 656 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 209, 637, 216, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 217, 637, 224, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 194, 388, 201, 397 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 258, 318, 264, 327 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 266, 318, 273, 327 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 160, 269, 167, 278 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 72, 249, 79, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 277, 139, 283, 148 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 497, 727, 504, 736 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 363, 647, 370, 656 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 337, 617, 344, 626 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 353, 488, 360, 497 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 353, 388, 360, 397 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 434, 239, 441, 248 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 340, 139, 347, 148 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 448, 139, 455, 148 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 358, 119, 365, 128 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 409, 69, 416, 78 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 1334 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 233, 717, 240, 726 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 170, 667, 177, 676 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 85, 607, 92, 616 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 76, 587, 82, 596 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 286, 488, 293, 497 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 68, 474, 72, 483 Flags: Print AppearanceDictionary: true Destination: 33 Annotation: Subtype: Link Rect: 109, 424, 113, 433 Flags: Print AppearanceDictionary: true Destination: 50 Annotation: Subtype: Link Rect: 69, 364, 74, 373 Flags: Print AppearanceDictionary: true Destination: 50 Annotation: Subtype: Link Rect: 338, 623, 342, 632 Flags: Print AppearanceDictionary: true Destination: 50 Annotation: Subtype: Link Rect: 335, 534, 340, 543 Flags: Print AppearanceDictionary: true Destination: 50 Annotation: Subtype: Link Rect: 453, 388, 460, 397 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 336, 255, 340, 264 Flags: Print AppearanceDictionary: true Destination: 75 Annotation: Subtype: Link Rect: 424, 149, 431, 158 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 416, 99, 423, 108 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 1335 Sequence: 4 Thumb: true Page: Label: 1336 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 286, 99, 293, 108 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 451, 548, 457, 557 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 491, 368, 498, 377 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 1337 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 214, 257, 283, 264 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 35, 248, 90, 255 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 429, 712, 549, 719 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 313, 703, 541, 710 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 313, 694, 327, 701 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 1338 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 116, 705, 194, 712 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 487, 643, 559, 650 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 311, 634, 368, 641 Flags: Print AppearanceDictionary: true Thumb: true Checksum: 09eb02e5 Type: CRC32 Checksum: fe6a2e0d71407d90fa318ac4e8a6eb69 Type: MD5 Checksum: 0084340d8e55d75c5ed46e7cd235e434e72ebeda Type: SHA-1