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Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a9273a8 Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@26a7b76d Item: Title: 2. Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4abdb505 Children: Item: Title: Outline placeholder Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7ce6a65d Children: Item: Title: 2.1.1. Study design and participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1500955a Item: Title: 2.1.2. Molecular procedures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e874448 Item: Title: Evidence before this study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@29b5cd00 Item: Title: Added value of this study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@60285225 Item: Title: Implications of all the available evidence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7113b13f Children: Item: Title: Outline placeholder Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@45820e51 Children: Item: Title: 2.1.3. Phylogenetic analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42d8062c Item: Title: 2.1.4. Ultra-deep sequencing data management Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6043cd28 Item: Title: 2.1.5. Study of the amino acid replacements located on the capsid surface Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb51256 Item: Title: 2.2. Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@59906517 Children: Item: Title: 2.3. Role of the funding source Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5bfbf16f Item: Title: 3. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@25af5db5 Item: Title: 4. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12cdcf4 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5bcea91b Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5f3a4b84 Item: Title: Declaration of interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@27f723 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@670b40af Item: Title: Appendix A. Supplementary data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4923ab24 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Info: Title: Evidence for positive selection of hepatitis A virus antigenic variants in vaccinated men-having-sex-with men patients: Implications for immunization policies Creator: Elsevier Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Wed Jan 16 02:45:11 CET 2019 ModDate: Wed Jan 23 16:51:32 CET 2019 ID: 0x765b72d4303407ef32380a58df86e9d3, 0x355369c1e5b750da9262ed1727139a11 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 697 ImageHeight: 180 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 272 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: 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IICCHF+AdvTT6b11a639.I Flags: Nonsymbolic FontBBox: -114, -250, 1083, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IICCHG+AdvTTc8c83e50+20 FontSubset: true FirstChar: 147 LastChar: 148 FontDescriptor: FontName: IICCHG+AdvTTc8c83e50+20 Flags: Nonsymbolic FontBBox: -208, -156, 947, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IICBJE+AdvTT0f485e03 FontSubset: true FirstChar: 97 LastChar: 116 FontDescriptor: FontName: IICBJE+AdvTT0f485e03 Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf Evidence for positive selection of hepatitis A virus antigenic variants in vaccinated men-having-sex-with men patients: Implications for immunization policies Aurora Sabrià Josep Gregori Damir Garcia-Cehic Susana Guix Tomàs Pumarola Sandra Manzanares-Laya Joan A. Caylà Albert Bosch Josep Quer Rosa M. Pintó Vaccine escape-mutants MSM Quasispecies Deep-sequencing EBioMedicine, 39 (2018) 348-357. doi:10.1016/j.ebiom.2018.11.023 journal EBioMedicine (c) 2018 Elsevier B.V. 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