ad599c37e8c8320c64ae080d5b268a71 pmc_30514339.pdf 1e9994a2b585df0d801b359aba092cf3a57eb4f6 pmc_30514339.pdf 3ddb071e54af76d05dcb95289faa69ab3b1c1f684aff42e7f99700baa516b773 pmc_30514339.pdf Title: Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data Subject: Critical Care, 2018, doi:10.1186/s13054-018-2076-z Keywords: Prognosis,Outcomes,Hematologic,Neoplasms,Intensive care units,Mechanical ventilation,Neutropenia Author: Quentin Georges Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Wed Nov 28 22:59:21 2018 CET ModDate: Tue Dec 4 14:52:33 2018 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 940921 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IHIJKH+SlmbwrAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 8 0 IHIJPG+FkymkcAdvTTe45e47d2 Type 1C WinAnsi yes yes no 9 0 IHIJPH+TbqlfrAdvTTb5929f4c Type 1C WinAnsi yes yes no 64 0 IHIJPI+NpvmkfAdvTT99c4c969 Type 1C WinAnsi yes yes no 12 0 IHIJPJ+VktpclAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 65 0 IHIJPK+JfnsgrAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 66 0 MyriadPro-Regular Type 1 Custom yes no no 10 0 IHIKPF+TctmdpAdvTT7329fd89.I Type 1C WinAnsi yes yes no 14 0 IHILCH+PxmrhtAdvTT86d47313+20 Type 1C WinAnsi yes yes no 11 0 IHILBG+KtkqxlAdvTT86d47313 Type 1C WinAnsi yes yes no 13 0 IHILIG+XvcwscAdvTT8861b38f.I Type 1C WinAnsi yes yes no 126 0 IHIPPL+RlgpvpAdvP4C4E74 Type 1C Custom yes yes no 175 0 IHJAAM+BspfxjAdvTT43ccf47d Type 1C WinAnsi yes yes no 176 0 IHJACM+SpdgqmAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 205 0 IHJACN+MsvvwcAdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 206 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-29 02:41:39 CEST RepresentationInformation: pmc_30514339.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2019-08-12 03:39:00 CEST Size: 940921 Format: PDF Version: 1.5 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR3' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR19' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR27' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR48' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR36' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR37' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR44' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR45' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR42' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR43' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR47' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR41' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR40' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR31' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR39' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR51' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR52' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR53' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR54' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR55' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR56' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR57' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR58' cannot be found Offset: 714127 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR59' cannot be found Offset: 714127 MIMEtype: application/pdf PDFMetadata: Objects: 459 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Systematic review registration Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Study outcome and definitions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Search strategy and eligibility assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Data and quality assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Children: Item: Title: Characteristics of included studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Characteristics of the patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Outcome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Influence of neutropenia in predefined subgroups Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Key messages Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Additional file Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Abbreviations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Authors’ contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Ethics approval and consent to participate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Publisher’s Note Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Author details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Info: Title: Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data Author: Quentin Georges Subject: Critical Care, 2018, doi:10.1186/s13054-018-2076-z Keywords: Prognosis,Outcomes,Hematologic,Neoplasms,Intensive care units,Mechanical ventilation,Neutropenia Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Wed Nov 28 22:59:21 CET 2018 ModDate: Tue Dec 04 14:52:33 CET 2018 ID: 0xdf5cb334e2bb9e045b6c7a65873b48a3, 0x6490f5cd701665e2ffd3bee8c5092ebb Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 54 ImageHeight: 103 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 95 ImageHeight: 91 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 1342 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1949 ImageHeight: 1367 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: IHIJPH+TbqlfrAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: IHIJPH+TbqlfrAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIJPJ+VktpclAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: IHIJPJ+VktpclAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIJPK+JfnsgrAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: IHIJPK+JfnsgrAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIJKH+SlmbwrAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: IHIJKH+SlmbwrAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIJPG+FkymkcAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: IHIJPG+FkymkcAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -46, -250, 1126, 879 FontFile: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: IHILCH+PxmrhtAdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: IHILCH+PxmrhtAdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIJPI+NpvmkfAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: IHIJPI+NpvmkfAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHILBG+KtkqxlAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: IHILBG+KtkqxlAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHJACM+SpdgqmAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: IHJACM+SpdgqmAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIKPF+TctmdpAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: IHIKPF+TctmdpAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHJACN+MsvvwcAdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: IHJACN+MsvvwcAdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHIPPL+RlgpvpAdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: IHIPPL+RlgpvpAdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: IHJAAM+BspfxjAdvTT43ccf47d FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: IHJAAM+BspfxjAdvTT43ccf47d Flags: Serif, Nonsymbolic FontBBox: -20, -250, 1010, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IHILIG+XvcwscAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 110 FontDescriptor: FontName: IHILIG+XvcwscAdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding XMP: Prognosis,Outcomes,Hematologic,Neoplasms,Intensive care units,Mechanical ventilation,Neutropenia Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) application/pdf 10.1186/s13054-018-2076-z Critical Care Critical Care, 2018, doi:10.1186/s13054-018-2076-z Prognosis Outcomes Hematologic Neoplasms Intensive care units Mechanical ventilation Neutropenia Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data Quentin Georges Elie Azoulay Djamel Mokart Marcio Soares Kyeongman Jeon Sandra Oeyen Chin Kook Rhee Pascale Gruber Marlies Ostermann Quentin A. Hill Pieter Depuydt Christelle Ferra Anne-Claire Toffart Peter Schellongowski Alice Müller Virginie Lemiale Fabien Tinquaut Aurélie Bourmaud Michaël Darmon 2018-12-04T14:52:33+01:00 2018-11-29T05:59:21+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode 2018-12-04T14:52:33+01:00 uuid:c9551fee-4954-4f65-a999-50d12b9e6a99 uuid:9db635e8-2fcf-4658-abb8-3c17b4ceac2f default 1 converted uuid:d8a089c6-fb4c-4754-a0e3-417cd3a447ad converted to PDF/A-2b pdfToolbox 2018-11-29T06:07:04+08:00 2 B Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx PDF/X ID Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 484, 657, 538, 679 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 245, 222, 315, 232 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 135, 189, 143 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 239, 65, 357, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 182, 41, 321, 48 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 93, 669, 98, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 105, 669, 110, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 280, 657, 285, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 192, 645, 197, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 633, 64, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 214, 609, 219, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 224, 609, 229, 618 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 59, 561, 64, 570 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 70, 561, 80, 570 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 128, 525, 138, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 143, 525, 152, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 232, 465, 241, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 259, 453, 269, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 182, 441, 191, 450 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 105, 405, 114, 414 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 166, 333, 175, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 262, 297, 271, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 141, 69, 150 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 261, 117, 271, 126 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 463, 657, 538, 666 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 645, 537, 654 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 633, 400, 642 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 496, 609, 501, 618 Flags: Print AppearanceDictionary: true Destination: 62 Annotation: Subtype: Link Rect: 491, 537, 501, 546 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 336, 369, 346, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 353, 369, 363, 378 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 493, 153, 503, 162 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 397, 69, 538, 78 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 57, 500, 66 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 116, 658, 123, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 125, 644, 133, 652 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 110, 630, 117, 638 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 107, 616, 115, 624 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 117, 602, 125, 610 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 148, 588, 155, 596 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 109, 574, 117, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 560, 126, 568 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 113, 546, 121, 554 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 532, 125, 540 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 141, 518, 149, 526 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 76, 495, 84, 503 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 481, 125, 489 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 467, 125, 475 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 140, 453, 148, 461 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 114, 425, 121, 433 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 110, 411, 117, 419 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 108, 397, 116, 405 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 119, 383, 127, 391 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 119, 369, 127, 377 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 114, 355, 122, 363 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 341, 126, 349 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 327, 126, 335 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 120, 313, 127, 321 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 122, 299, 130, 307 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 122, 285, 126, 293 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 124, 271, 132, 279 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 129, 257, 136, 265 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 120, 243, 127, 251 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 56, 693, 289, 702 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 56, 681, 135, 690 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 378, 429, 383, 438 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 391, 429, 396, 438 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 400, 429, 410, 438 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 429, 425, 438 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 259, 657, 264, 666 Flags: Print AppearanceDictionary: true Destination: 62 Annotation: Subtype: Link Rect: 144, 609, 153, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 197, 609, 206, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 232, 519, 237, 528 Flags: Print AppearanceDictionary: true Destination: 140 Annotation: Subtype: Link Rect: 152, 495, 157, 504 Flags: Print AppearanceDictionary: true Destination: 140 Annotation: Subtype: Link Rect: 371, 633, 376, 642 Flags: Print AppearanceDictionary: true Destination: 159 Annotation: Subtype: Link Rect: 398, 633, 403, 642 Flags: Print AppearanceDictionary: true Destination: 159 Annotation: Subtype: Link Rect: 369, 549, 374, 558 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 487, 405, 492, 414 Flags: Print AppearanceDictionary: true Destination: 202 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 523, 549, 533, 558 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 394, 525, 404, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 525, 525, 535, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 307, 501, 317, 510 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 359, 453, 368, 462 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 173, 693, 177, 702 Flags: Print AppearanceDictionary: true Destination: 202 Annotation: Subtype: Link Rect: 183, 693, 192, 702 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 226, 597, 236, 606 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 80, 561, 90, 570 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 110, 513, 120, 522 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 174, 333, 184, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 191, 333, 201, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 129, 297, 139, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 148, 297, 158, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 141, 261, 151, 270 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 157, 261, 166, 270 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 76, 225, 86, 234 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 348, 681, 358, 690 Flags: Print AppearanceDictionary: true Destination: 219 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 61, 671, 118, 678 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 9 Thumb: true Page: Sequence: 10 Thumb: true Checksum: 273391d3 Type: CRC32 Checksum: ad599c37e8c8320c64ae080d5b268a71 Type: MD5 Checksum: 1e9994a2b585df0d801b359aba092cf3a57eb4f6 Type: SHA-1