922597d1076ee03dc0b8a49f9775be31 pmc_30572930.pdf 4b847aad6579a51763a8596d51e2bf15d3b92fe0 pmc_30572930.pdf ff2329b649b5dbe30e25e0c2d91a01fff2aab10dfb5ebe8f6a4938440c50552d pmc_30572930.pdf Title: Gut colonization by a novel Clostridium species is associated with the onset of epizootic rabbit enteropathy Subject: Veterinary Research, https://doi.org/10.1186/s13567-018-0617-8 Author: Ana Djukovic Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Dec 18 10:22:06 2018 CET ModDate: Thu Dec 20 15:11:49 2018 CET Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1414280 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-Light Type 1C Custom yes no yes 68 0 MyriadPro-It Type 1C Custom yes no yes 31 0 MyriadPro-LightIt Type 1C WinAnsi yes no yes 69 0 MyriadPro-Bold Type 1C Custom yes no yes 32 0 WarnockPro-Regular Type 1C Custom yes no yes 33 0 WarnockPro-It Type 1C Custom yes no yes 30 0 MyriadPro-Regular Type 1C Custom yes no yes 36 0 MyriadPro-Semibold Type 1C Custom yes no yes 34 0 JCGCPD+MTSY Type 1C Custom yes yes yes 35 0 FYCGON+STIXMath-Regular Type 1C WinAnsi yes yes yes 50 0 KOTIPD+EuclidSymbol Type 1C Custom yes yes yes 51 0 MyriadPro-SemiboldIt Type 1C WinAnsi yes no yes 64 0 FBBBON+Arial-BoldMT Type 1C WinAnsi yes yes no 65 0 FBBBON+ArialMT Type 1C WinAnsi yes yes no 66 0 FBBBON+ArialMT Type 1C WinAnsi yes yes no 67 0 FBBBON+Arial-BoldMT Type 1C WinAnsi yes yes no 132 0 FBBBON+ArialMT Type 1C WinAnsi yes yes no 133 0 FBBBON+STIX-Regular Type 1C Custom yes yes yes 134 0 FBBBON+ArialMT Type 1C WinAnsi yes yes no 153 0 FBBBON+Arial-ItalicMT Type 1C WinAnsi yes yes no 154 0 MyriadPro-It2 Type 1C WinAnsi yes no no 163 0 MyriadPro-Regular2 Type 1C WinAnsi yes no no 164 0 MyriadPro-BoldIt Type 1C WinAnsi yes no no 165 0 MyriadPro-Bold2 Type 1C WinAnsi yes no no 166 0 KBKAGD+Helvetica Type 1C WinAnsi yes yes no 167 0 GUMFCL+OregonLDOBookSinistral Type 1C WinAnsi yes yes no 279 0 GUMFCL+OpenSans-Light Type 1C Custom yes yes no 273 0 GUMFCL+OpenSans-Bold Type 1C WinAnsi yes yes no 276 0 GUMFCL+OpenSans-Extrabold Type 1C WinAnsi yes yes no 269 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-01-19 05:16:07 CET RepresentationInformation: pmc_30572930.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2019-05-20 03:37:30 CEST Size: 1414280 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 1260 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Gut colonization by a novel Clostridium species is associated with the onset of epizootic rabbit enteropathy Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Materials and methods Children: Item: Title: Rabbit model and housing conditions Item: Title: Identification of rabbits developing ERE and defining the day of ERE onset Item: Title: Sample collection and DNA extraction Item: Title: 16S rRNA gene amplification and high-throughput sequencing Item: Title: 16S rRNA sequencing analysis Item: Title: Principal coordinate of analysis Item: Title: Isolation of Clostridium cuniculi Item: Title: Experimental reproduction of ERE Item: Title: Sequencing of the C. cuniculi genome Item: Title: Analysis of the C. cuniculi genome Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Epizootic rabbit enteropathy is characterized by dysbiosis of the intestinal microbiota after disease onset Item: Title: The intestinal microbiota of healthy rabbits and those that develop ERE does not differ before disease onset Item: Title: Bloom of a novel Clostridium species characterizes the ERE onset Item: Title: Discussion Item: Title: Competing interests Item: Title: References Info: Title: Gut colonization by a novel Clostridium species is associated with the onset of epizootic rabbit enteropathy Author: Ana Djukovic Subject: Veterinary Research, https://doi.org/10.1186/s13567-018-0617-8 Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Dec 18 10:52:06 CET 2018 ModDate: Thu Dec 20 15:11:49 CET 2018 ID: 0x219524c62d57e0d2df058313d6938563, 0x761daeb969cc262c60ef0314bbd77be2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 5 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 2 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 40 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 81 ImageHeight: 84 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 74 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 39 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 6 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 96 ImageHeight: 90 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 46 ImageHeight: 15 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 7 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 46 ImageHeight: 66 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 12 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 8 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 13 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 22 ImageHeight: 8 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3 ImageHeight: 3 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 44 ImageHeight: 222 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: MyriadPro-SemiboldIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldIt Flags: Nonsymbolic, Italic FontBBox: -193, -250, 1164, 972 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: FBBBON+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: FBBBON+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1018 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FBBBON+ArialMT FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: FBBBON+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1006 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FBBBON+ArialMT FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: FBBBON+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1006 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Light FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Light Flags: Nonsymbolic FontBBox: -49, -250, 1046, 883 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FBBBON+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: FBBBON+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1018 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-LightIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-LightIt Flags: Nonsymbolic, Italic FontBBox: -121, -250, 1007, 863 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: FBBBON+ArialMT FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: FBBBON+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1006 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FBBBON+STIX-Regular FontSubset: true FirstChar: 31 LastChar: 32 FontDescriptor: FontName: FBBBON+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FBBBON+ArialMT FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: FBBBON+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1006 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FBBBON+Arial-ItalicMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: FBBBON+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: WarnockPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WarnockPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -221, -533, 1474, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WarnockPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WarnockPro-Regular Flags: Serif, Nonsymbolic FontBBox: -177, -533, 1474, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: JCGCPD+MTSY FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: JCGCPD+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-It2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It2 Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Regular2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular2 Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-BoldIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-BoldIt Flags: Nonsymbolic, Italic FontBBox: -201, -250, 1225, 987 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Bold2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold2 Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KBKAGD+Helvetica FontSubset: true FirstChar: 46 LastChar: 115 FontDescriptor: FontName: KBKAGD+Helvetica Flags: Nonsymbolic FontBBox: -166, -225, 1000, 931 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FYCGON+STIXMath-Regular FontSubset: true FirstChar: 32 LastChar: 174 FontDescriptor: FontName: FYCGON+STIXMath-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -524, 3238, 2566 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: KOTIPD+EuclidSymbol FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: KOTIPD+EuclidSymbol Flags: Symbolic FontBBox: -166, -253, 1090, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: 2018-12-18T14:52:06+05:30 Springer 2018-12-20T15:11:49+01:00 2018-12-20T15:11:49+01:00 application/pdf https://doi.org/10.1186/s13567-018-0617-8 BioMed Central Veterinary Research, https://doi.org/10.1186/s13567-018-0617-8 Gut colonization by a novel Clostridium species is associated with the onset of epizootic rabbit enteropathy Ana Djukovic Marc Garcia-Garcera Eugenio Martínez-Paredes Sandrine Isaac Alejandro Artacho Jorge Martínez Carles Ubeda 10.1186/s13567-018-0617-8 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s13567-018-0617-8 10.1186/s13567-018-0617-8 1297-9716 journal Veterinary Research The Author(s) 2010-04-23 true 10.1186/s13567-018-0617-8 noindex springer.com springerlink.com VoR uuid:8a235a79-7ba9-47cb-b559-fe28e9657f67 uuid:46299f98-bdde-49f0-9a47-32558c170ade default 1 converted uuid:cce543cd-c13c-4d50-82c0-6ee4f4aa6384 converted to PDF/A-2b pdfToolbox 2018-12-18T14:52:39+05:30 2 B http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal Volume number volume Text internal Issue number number Text internal Starting page startingPage Text internal Ending page endingPage Text external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 182, 80, 307, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 443, 64, 525, 56 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 180, 56, 247, 48 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 92, 286, 97, 274 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 103, 286, 108, 274 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 224, 274, 229, 262 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 83, 214, 88, 202 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 82, 190, 87, 178 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 92, 190, 96, 178 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 432, 299, 437, 287 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 443, 299, 448, 287 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 453, 299, 458, 287 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 448, 263, 453, 251 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 426, 227, 431, 215 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 436, 227, 441, 215 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 482, 167, 487, 155 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 452, 119, 457, 107 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 484, 683, 541, 658 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 221, 680, 231, 668 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 236, 680, 246, 668 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 275, 644, 285, 632 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 125, 476, 135, 464 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 307, 596, 312, 584 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 318, 596, 323, 584 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 494, 524, 499, 512 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 441, 476, 446, 464 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 391, 452, 396, 440 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 368, 416, 373, 404 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 397, 212, 402, 200 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 470, 176, 475, 164 Flags: Print AppearanceDictionary: true Destination: 223 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 224, 668, 234, 656 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 280, 548, 285, 536 Flags: Print AppearanceDictionary: true Destination: 107 Annotation: Subtype: Link Rect: 275, 488, 285, 476 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 512, 632, 522, 620 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 441, 620, 451, 608 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 364, 428, 374, 416 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 510, 188, 520, 176 Flags: Print AppearanceDictionary: true Destination: 262 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 369, 669, 531, 657 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 345, 645, 350, 633 Flags: Print AppearanceDictionary: true Destination: 56 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 419, 417, 429, 404 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 427, 405, 437, 392 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 483, 369, 493, 356 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 450, 297, 459, 284 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 307, 261, 317, 248 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 396, 261, 406, 248 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 471, 261, 481, 248 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 390, 237, 400, 224 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 473, 225, 483, 212 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 332, 105, 342, 92 Flags: Print AppearanceDictionary: true Destination: 262 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 231, 681, 241, 668 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 162, 621, 172, 608 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 146, 393, 156, 380 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 271, 237, 280, 224 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 139, 213, 149, 200 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 120, 117, 125, 104 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 332, 693, 337, 680 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 435, 561, 445, 548 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 423, 465, 428, 452 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 396, 429, 401, 416 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 439, 285, 444, 272 Flags: Print AppearanceDictionary: true Destination: 139 Annotation: Subtype: Link Rect: 320, 177, 325, 164 Flags: Print AppearanceDictionary: true Destination: 107 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 406, 444, 411, 432 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 528, 408, 533, 396 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 417, 384, 422, 372 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 442, 360, 447, 348 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 528, 324, 533, 312 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 439, 264, 448, 252 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 478, 204, 538, 192 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 304, 192, 340, 180 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 432, 192, 437, 180 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 373, 120, 378, 108 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 210, 192, 215, 179 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 212, 168, 217, 155 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 282, 156, 287, 143 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 101, 132, 195, 119 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 264, 132, 269, 119 Flags: Print AppearanceDictionary: true Destination: 223 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 126, 405, 131, 392 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 273, 333, 278, 320 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 166, 213, 171, 200 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 382, 369, 387, 356 Flags: Print AppearanceDictionary: true Destination: 107 Annotation: Subtype: Link Rect: 522, 297, 527, 284 Flags: Print AppearanceDictionary: true Destination: 107 Annotation: Subtype: Link Rect: 457, 261, 462, 248 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 404, 225, 409, 212 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 503, 189, 508, 176 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 525, 81, 529, 68 Flags: Print AppearanceDictionary: true Destination: 262 Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 370, 193, 443, 183 Flags: Print AppearanceDictionary: true Destination: 3 Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 60, 645, 159, 632 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 179, 561, 184, 548 Flags: Print AppearanceDictionary: true Destination: 139 Annotation: Subtype: Link Rect: 88, 513, 93, 500 Flags: Print AppearanceDictionary: true Destination: 139 Annotation: Subtype: Link Rect: 126, 417, 131, 404 Flags: Print AppearanceDictionary: true Destination: 139 Annotation: Subtype: Link Rect: 89, 381, 94, 368 Flags: Print AppearanceDictionary: true Destination: 139 Annotation: Subtype: Link Rect: 236, 249, 241, 236 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 236, 213, 241, 200 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 81, 165, 179, 152 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 254, 105, 259, 92 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 365, 525, 369, 512 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 467, 489, 472, 476 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 382, 405, 387, 392 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 382, 333, 391, 320 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 448, 321, 458, 308 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 378, 273, 383, 260 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 463, 81, 473, 68 Flags: Print AppearanceDictionary: true Destination: 262 Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 249, 453, 259, 440 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 84, 297, 89, 284 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 275, 117, 285, 104 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 59, 81, 69, 68 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 509, 645, 514, 632 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 387, 549, 397, 536 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 402, 549, 412, 536 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 400, 477, 410, 464 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 523, 453, 533, 440 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 406, 177, 415, 164 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 307, 105, 317, 92 Flags: Print AppearanceDictionary: true Destination: 262 Thumb: true Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 176, 669, 181, 656 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 185, 669, 190, 656 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 194, 669, 199, 656 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 179, 573, 184, 560 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 59, 249, 69, 236 Flags: Print AppearanceDictionary: true Destination: 262 Annotation: Subtype: Link Rect: 174, 165, 179, 152 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 268, 129, 273, 116 Flags: Print AppearanceDictionary: true Destination: 249 Annotation: Subtype: Link Rect: 310, 486, 363, 476 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 500, 404, 529, 395 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 310, 395, 350, 386 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 397, 395, 401, 386 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 310, 356, 363, 346 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 382, 274, 386, 265 Flags: Print AppearanceDictionary: true Destination: 223 Annotation: Subtype: Link Rect: 310, 253, 363, 243 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 310, 177, 363, 167 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 310, 110, 363, 100 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 131, 652, 134, 644 Flags: Print AppearanceDictionary: true Destination: 56 Annotation: Subtype: Link Rect: 62, 604, 115, 595 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 62, 510, 115, 501 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 62, 452, 115, 443 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 62, 322, 115, 313 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 14 Thumb: true Checksum: ae8fefc8 Type: CRC32 Checksum: 922597d1076ee03dc0b8a49f9775be31 Type: MD5 Checksum: 4b847aad6579a51763a8596d51e2bf15d3b92fe0 Type: SHA-1 Checksum: ff2329b649b5dbe30e25e0c2d91a01fff2aab10dfb5ebe8f6a4938440c50552d Type: SHA-256