3150b7e6eec8b2337538c6fc409699e8 pmc_30587840.pdf 2a93bf1b1a5f9097a846c9830a261135730aeee0 pmc_30587840.pdf 2394435069147fb30271137a4d6e0f52561779256f89c8df7a8f240e503e5f28 pmc_30587840.pdf Title: ZIF Nanocrystal-Based Surface Acoustic Wave (SAW) Electronic Nose to Detect Diabetes in Human Breath Subject: In the present work, a novel, portable and innovative eNose composed of a surface acoustic wave (SAW) sensor array based on zeolitic imidazolate frameworks, ZIF-8 and ZIF-67 nanocrystals (pure and combined with gold nanoparticles), as sensitive layers has been tested as a non-invasive system to detect different disease markers, such as acetone, ethanol and ammonia, related to the diagnosis and control of diabetes mellitus through exhaled breath. The sensors have been prepared by spin coating, achieving continuous sensitive layers at the surface of the SAW device. Low concentrations (5 ppm, 10 ppm and 25 ppm) of the marker analytes were measured, obtaining high sensitivities, good reproducibility, short time response and fast signal recovery. Keywords: eNose; gas sensor; SAW; surface acoustic wave; Love wave; diabetes; breath; VOC; ZIF; Zeolite Author: Fabio A. Bahos, Arianee Sainz-Vidal, Celia Sánchez-Pérez, José M. Saniger, Isabel Gràcia, María M. Saniger-Alba and Daniel Matatagui Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.17 CreationDate: Wed Dec 26 17:19:36 2018 CET ModDate: Wed Dec 26 17:19:36 2018 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 3635471 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XHZNVE+URWPalladioL-Ital Type 1 Custom yes yes no 97 0 JLSSWX+URWPalladioL-Bold Type 1 Custom yes yes no 98 0 VJNASK+VnURWPalladioL-Bold Type 1 Custom yes yes no 99 0 JYFKTG+URWPalladioL-Roma Type 1 Custom yes yes no 100 0 RPHYKK+VnURWPalladioL Type 1 Custom yes yes no 101 0 YHYESE+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 106 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 123 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 124 0 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