bfcdec2cebebd3be226461b8170650de 2019_Curr_Animals_Goat_italian_breeds_fatty_acids.pdf 1daec66123b94cadb901b5fa8df6e8dd346f7431 2019_Curr_Animals_Goat_italian_breeds_fatty_acids.pdf 3e98042042af62df1a9ee04c2b012876e89b47328314e3f051919e35f00faffe 2019_Curr_Animals_Goat_italian_breeds_fatty_acids.pdf Title: Effects of Breed and Stage of Lactation on Milk Fatty Acid Composition of Italian Goat Breeds Subject: Fatty acid (FA) profile plays an important role on human health and on sensory quality of dairy products. There is few information about breed influence on milk FA profile of local goat breeds. This study aimed to characterize and compare the milk FA profile of 5 local endangered goat breeds (Garganica, Girgentana, Jonica, Maltese, and Mediterranean Red) and a cosmopolitan breed (Saanen) reared in the same farm during a complete lactation. A total of 252 milk samples were collected monthly from 42 goats (7 goats per breed) and analyzed for gross composition and FA profile. Individual FA was determined using gas-chromatography. Data were analyzed using a mixed model with repeated measures with breed and week of lactation as fixed effects. Results showed that the FA profile was significantly affected by week of lactation and only few FA by breed effect (p < 0.05). Overall, the main differences were found between Saanen and local breeds. This study contributed to the characterization of goat milk FA profile, and it may be of interest for the valorization of milk from local goat breeds which seem to have a healthier profile than milk of the cosmopolitan breed. Keywords: atherogenicity index; conjugated linoleic acids; desaturation index; local goat breeds; fatty acids Author: Sarah Currò, Carmen L. Manuelian, Massimo De Marchi, Salvatore Claps, Domenico Rufrano and Gianluca Neglia Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.17 CreationDate: Thu Oct 3 16:35:52 2019 CEST ModDate: Tue Dec 3 10:45:59 2019 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 701162 bytes Optimized: yes PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- UEFINU+URWPalladioL-Ital Type 1 Custom yes yes no 544 0 KXPBXH+URWPalladioL-Bold Type 1 Custom yes yes no 547 0 DPBIRG+Rpxb Type 1 Builtin yes yes no 550 0 VMHYJM+URWPalladioL-Roma Type 1 Custom yes yes no 553 0 FATHTC+Rpxr Type 1 Builtin yes yes no 556 0 HHMDGK+Pxsy Type 1 Builtin yes yes no 559 0 WLFTRW+VnURWPalladioL-Bold Type 1 Custom yes yes no 563 0 SZMRXJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 567 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 579 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 582 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 585 0 MPUDFL+PazoMath Type 1 Builtin yes yes no 295 0 OQMSDZ+EURM10 Type 1 Builtin yes yes no 299 0 PHWYMS+VnURWPalladioL Type 1 Custom yes yes no 302 0 GBLQZB+Rpxi Type 1 Builtin yes yes no 305 0 JOZXHD+TeX-tipa10 Type 1 Builtin yes yes no 308 0 PSFVHR+TeX-tipa8 Type 1 Builtin yes yes no 306 0 TBHYIS+URWPalladioL-BoldItal Type 1 Custom yes yes no 311 0 VSHNAE+Rpcxr Type 1 Builtin yes yes no 312 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-04-18 02:45:02 CEST RepresentationInformation: 2019_Curr_Animals_Goat_italian_breeds_fatty_acids.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-04-10 06:14:08 CEST Size: 701162 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Animals and Management Conditions Item: Title: Sample Collection and Chemical Analysis Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: Breed Effect Item: Title: Effect of Stage of Lactation Item: Title: Discussion Children: Item: Title: Breed Effect Item: Title: Effect of Stage of Lactation Item: Title: Conclusions Item: Title: References Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: UEFINU+URWPalladioL-Ital FontSubset: true FirstChar: 44 LastChar: 121 FontDescriptor: FontName: UEFINU+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: KXPBXH+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: KXPBXH+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: DPBIRG+Rpxb FontSubset: true FirstChar: 11 LastChar: 60 FontDescriptor: FontName: DPBIRG+Rpxb Flags: Symbolic FontBBox: -57, -266, 932, 729 FontFile: true Font: BaseFont: MPUDFL+PazoMath FontSubset: true FirstChar: 68 LastChar: 68 FontDescriptor: FontName: MPUDFL+PazoMath Flags: Symbolic FontBBox: -40, -283, 878, 946 FontFile: true Font: BaseFont: VMHYJM+URWPalladioL-Roma FontSubset: true FirstChar: 1 LastChar: 252 FontDescriptor: FontName: VMHYJM+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: OQMSDZ+EURM10 FontSubset: true FirstChar: 11 LastChar: 27 FontDescriptor: FontName: OQMSDZ+EURM10 Flags: Symbolic FontBBox: -32, -243, 1060, 720 FontFile: true Font: BaseFont: FATHTC+Rpxr FontSubset: true FirstChar: 11 LastChar: 61 FontDescriptor: FontName: FATHTC+Rpxr Flags: Symbolic FontBBox: -40, -283, 904, 728 FontFile: true Font: BaseFont: PHWYMS+VnURWPalladioL FontSubset: true FirstChar: 129 LastChar: 254 FontDescriptor: FontName: PHWYMS+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: HHMDGK+Pxsy FontSubset: true FirstChar: 0 LastChar: 14 FontDescriptor: FontName: HHMDGK+Pxsy Flags: Symbolic FontBBox: -21, -994, 1292, 912 FontFile: true Font: BaseFont: GBLQZB+Rpxi FontSubset: true FirstChar: 11 LastChar: 11 FontDescriptor: FontName: GBLQZB+Rpxi Flags: Symbolic FontBBox: -162, -280, 856, 733 FontFile: true Font: BaseFont: PSFVHR+TeX-tipa8 FontSubset: true FirstChar: 69 LastChar: 69 FontDescriptor: FontName: PSFVHR+TeX-tipa8 Flags: Symbolic FontBBox: -75, -303, 859, 767 FontFile: true Font: BaseFont: WLFTRW+VnURWPalladioL-Bold FontSubset: true FirstChar: 225 LastChar: 225 FontDescriptor: FontName: WLFTRW+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JOZXHD+TeX-tipa10 FontSubset: true FirstChar: 69 LastChar: 69 FontDescriptor: FontName: JOZXHD+TeX-tipa10 Flags: Symbolic FontBBox: -70, -296, 812, 771 FontFile: true Font: BaseFont: TBHYIS+URWPalladioL-BoldItal FontSubset: true FirstChar: 80 LastChar: 112 FontDescriptor: FontName: TBHYIS+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VSHNAE+Rpcxr FontSubset: true FirstChar: 169 LastChar: 169 FontDescriptor: FontName: VSHNAE+Rpcxr Flags: Symbolic FontBBox: -212, -286, 1344, 973 FontFile: true XMP: application/pdf Sarah Currò, Carmen L. Manuelian, Massimo De Marchi, Salvatore Claps, Domenico Rufrano and Gianluca Neglia Fatty acid (FA) profile plays an important role on human health and on sensory quality of dairy products. There is few information about breed influence on milk FA profile of local goat breeds. This study aimed to characterize and compare the milk FA profile of 5 local endangered goat breeds (Garganica, Girgentana, Jonica, Maltese, and Mediterranean Red) and a cosmopolitan breed (Saanen) reared in the same farm during a complete lactation. A total of 252 milk samples were collected monthly from 42 goats (7 goats per breed) and analyzed for gross composition and FA profile. Individual FA was determined using gas-chromatography. Data were analyzed using a mixed model with repeated measures with breed and week of lactation as fixed effects. Results showed that the FA profile was significantly affected by week of lactation and only few FA by breed effect (p < 0.05). Overall, the main differences were found between Saanen and local breeds. This study contributed to the characterization of goat milk FA profile, and it may be of interest for the valorization of milk from local goat breeds which seem to have a healthier profile than milk of the cosmopolitan breed. Effects of Breed and Stage of Lactation on Milk Fatty Acid Composition of Italian Goat Breeds 2019-10-03T16:35:52+02:00 LaTeX with hyperref package 2019-12-03T10:45:59+01:00 2019-12-03T10:45:59+01:00 atherogenicity index; conjugated linoleic acids; desaturation index; local goat breeds; fatty acids pdfTeX-1.40.17 False This is pdfTeX, Version 3.14159265-2.6-1.40.17 (TeX Live 2016/W32TeX) kpathsea version 6.2.2 uuid:0bca5b73-ea91-4732-a9e9-cefc555025f9 uuid:336488ba-eb59-4e4a-8d56-80f19dd832c9 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 75, 757, 206, 793 Annotation: Subtype: Link Rect: 474, 757, 519, 793 Annotation: Subtype: Link Rect: 137, 660, 148, 674 Annotation: Subtype: Link Rect: 257, 660, 268, 674 Annotation: Subtype: Link Rect: 272, 647, 283, 660 Annotation: Subtype: Link Rect: 466, 523, 518, 542 Annotation: Subtype: Link Rect: 417, 84, 424, 93 ActionDest: 38 Annotation: Subtype: Link Rect: 162, 38, 231, 50 Annotation: Subtype: Link Rect: 403, 38, 519, 50 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 321, 743, 328, 752 ActionDest: 38 Annotation: Subtype: Link Rect: 128, 729, 135, 738 ActionDest: 38 Annotation: Subtype: Link Rect: 281, 675, 288, 684 ActionDest: 38 Annotation: Subtype: Link Rect: 440, 661, 447, 671 ActionDest: 38 Annotation: Subtype: Link Rect: 447, 661, 454, 671 ActionDest: 38 Annotation: Subtype: Link Rect: 417, 648, 424, 657 ActionDest: 38 Annotation: Subtype: Link Rect: 508, 634, 515, 644 ActionDest: 38 Annotation: Subtype: Link Rect: 462, 621, 469, 630 ActionDest: 38 Annotation: Subtype: Link Rect: 472, 621, 479, 630 ActionDest: 38 Annotation: Subtype: Link Rect: 395, 607, 402, 617 ActionDest: 38 Annotation: Subtype: Link Rect: 372, 594, 379, 603 ActionDest: 38 Annotation: Subtype: Link Rect: 379, 594, 386, 603 ActionDest: 38 Annotation: Subtype: Link Rect: 155, 567, 162, 576 ActionDest: 38 Annotation: Subtype: Link Rect: 240, 553, 247, 562 ActionDest: 38 Annotation: Subtype: Link Rect: 248, 553, 260, 562 ActionDest: 41 Annotation: Subtype: Link Rect: 263, 540, 269, 549 ActionDest: 38 Annotation: Subtype: Link Rect: 112, 499, 124, 508 ActionDest: 41 Annotation: Subtype: Link Rect: 124, 499, 136, 508 ActionDest: 41 Annotation: Subtype: Link Rect: 296, 472, 308, 481 ActionDest: 41 Annotation: Subtype: Link Rect: 311, 472, 323, 481 ActionDest: 41 Annotation: Subtype: Link Rect: 106, 445, 118, 454 ActionDest: 41 Annotation: Subtype: Link Rect: 125, 418, 137, 427 ActionDest: 41 Annotation: Subtype: Link Rect: 325, 405, 337, 414 ActionDest: 41 Annotation: Subtype: Link Rect: 337, 405, 349, 414 ActionDest: 41 Annotation: Subtype: Link Rect: 288, 391, 300, 400 ActionDest: 41 Annotation: Subtype: Link Rect: 143, 378, 155, 387 ActionDest: 41 Annotation: Subtype: Link Rect: 338, 351, 350, 360 ActionDest: 41 Annotation: Subtype: Link Rect: 350, 351, 362, 360 ActionDest: 41 Annotation: Subtype: Link Rect: 343, 337, 354, 346 ActionDest: 41 Annotation: Subtype: Link Rect: 438, 324, 450, 333 ActionDest: 41 Annotation: Subtype: Link Rect: 348, 243, 360, 252 ActionDest: 41 Annotation: Subtype: Link Rect: 360, 242, 372, 252 ActionDest: 41 Annotation: Subtype: Link Rect: 249, 229, 260, 238 ActionDest: 41 Annotation: Subtype: Link Rect: 252, 202, 264, 211 ActionDest: 41 Annotation: Subtype: Link Rect: 133, 175, 145, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 145, 175, 157, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 342, 175, 354, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 357, 175, 369, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 465, 175, 477, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 478, 175, 490, 184 ActionDest: 44 Annotation: Subtype: Link Rect: 323, 161, 335, 171 ActionDest: 44 Annotation: Subtype: Link Rect: 406, 161, 418, 171 ActionDest: 44 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 131, 646, 143, 655 ActionDest: 41 Annotation: Subtype: Link Rect: 502, 619, 514, 628 ActionDest: 44 Annotation: Subtype: Link Rect: 270, 413, 277, 425 ActionDest: 4 Annotation: Subtype: Link Rect: 341, 389, 353, 398 ActionDest: 44 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 133, 715, 145, 725 ActionDest: 44 Annotation: Subtype: Link Rect: 453, 668, 465, 677 ActionDest: 44 Annotation: Subtype: Link Rect: 503, 537, 515, 547 ActionDest: 44 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 123, 632, 135, 641 ActionDest: 44 Annotation: Subtype: Link Rect: 136, 632, 148, 641 ActionDest: 44 Annotation: Subtype: Link Rect: 153, 311, 160, 323 ActionDest: 10 Annotation: Subtype: Link Rect: 462, 244, 469, 256 ActionDest: 10 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 111, 727, 118, 738 ActionDest: 18 Annotation: Subtype: Link Rect: 498, 551, 505, 562 ActionDest: 18 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 119, 551, 126, 563 ActionDest: 18 Annotation: Subtype: Link Rect: 462, 95, 469, 107 ActionDest: 26 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 147, 672, 154, 684 ActionDest: 26 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 118, 202, 129, 211 ActionDest: 41 Annotation: Subtype: Link Rect: 130, 202, 142, 211 ActionDest: 44 Annotation: Subtype: Link Rect: 135, 175, 147, 184 ActionDest: 44 Annotation: Subtype: Link Rect: 205, 107, 217, 116 ActionDest: 44 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 194, 729, 206, 738 ActionDest: 44 Annotation: Subtype: Link Rect: 448, 715, 460, 725 ActionDest: 44 Annotation: Subtype: Link Rect: 126, 661, 138, 671 ActionDest: 44 Annotation: Subtype: Link Rect: 457, 661, 469, 671 ActionDest: 44 Annotation: Subtype: Link Rect: 471, 634, 483, 644 ActionDest: 44 Annotation: Subtype: Link Rect: 218, 607, 230, 617 ActionDest: 44 Annotation: Subtype: Link Rect: 503, 594, 515, 603 ActionDest: 44 Annotation: Subtype: Link Rect: 348, 567, 360, 576 ActionDest: 44 Annotation: Subtype: Link Rect: 212, 553, 223, 562 ActionDest: 44 Annotation: Subtype: Link Rect: 455, 553, 467, 562 ActionDest: 44 Annotation: Subtype: Link Rect: 302, 526, 314, 535 ActionDest: 44 Annotation: Subtype: Link Rect: 385, 418, 397, 427 ActionDest: 44 Annotation: Subtype: Link Rect: 294, 391, 306, 400 ActionDest: 44 Annotation: Subtype: Link Rect: 405, 391, 417, 400 ActionDest: 44 Annotation: Subtype: Link Rect: 328, 324, 340, 333 ActionDest: 41 Annotation: Subtype: Link Rect: 442, 310, 454, 319 ActionDest: 41 Annotation: Subtype: Link Rect: 190, 270, 202, 279 ActionDest: 44 Annotation: Subtype: Link Rect: 286, 270, 298, 279 ActionDest: 41 Annotation: Subtype: Link Rect: 504, 229, 516, 238 ActionDest: 41 Annotation: Subtype: Link Rect: 375, 202, 387, 211 ActionDest: 41 Annotation: Subtype: Link Rect: 281, 175, 293, 184 ActionDest: 41 Annotation: Subtype: Link Rect: 175, 121, 187, 130 ActionDest: 44 Annotation: Subtype: Link Rect: 218, 80, 230, 90 ActionDest: 44 Annotation: Subtype: Link Rect: 297, 80, 309, 90 ActionDest: 47 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 170, 646, 182, 655 ActionDest: 41 Annotation: Subtype: Link Rect: 182, 646, 194, 655 ActionDest: 41 Annotation: Subtype: Link Rect: 221, 632, 233, 641 ActionDest: 47 Annotation: Subtype: Link Rect: 111, 619, 123, 628 ActionDest: 47 Annotation: Subtype: Link Rect: 133, 592, 145, 601 ActionDest: 47 Annotation: Subtype: Link Rect: 256, 592, 268, 601 ActionDest: 47 Annotation: Subtype: Link Rect: 491, 565, 503, 574 ActionDest: 44 Annotation: Subtype: Link Rect: 503, 565, 515, 574 ActionDest: 47 Annotation: Subtype: Link Rect: 402, 538, 414, 547 ActionDest: 47 Annotation: Subtype: Link Rect: 384, 511, 396, 520 ActionDest: 47 Annotation: Subtype: Link Rect: 480, 497, 492, 506 ActionDest: 47 Annotation: Subtype: Link Rect: 307, 470, 319, 479 ActionDest: 41 Annotation: Subtype: Link Rect: 421, 429, 433, 439 ActionDest: 41 Annotation: Subtype: Link Rect: 189, 389, 201, 398 ActionDest: 41 Annotation: Subtype: Link Rect: 207, 348, 219, 358 ActionDest: 41 Annotation: Subtype: Link Rect: 107, 321, 119, 331 ActionDest: 47 Annotation: Subtype: Link Rect: 322, 267, 334, 277 ActionDest: 47 Annotation: Subtype: Link Rect: 503, 254, 515, 263 ActionDest: 47 Annotation: Subtype: Link Rect: 401, 186, 413, 196 ActionDest: 47 Annotation: Subtype: Link Rect: 118, 132, 130, 142 ActionDest: 47 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 166, 742, 178, 752 ActionDest: 47 Annotation: Subtype: Link Rect: 380, 715, 392, 725 ActionDest: 47 Annotation: Subtype: Link Rect: 117, 688, 129, 698 ActionDest: 41 Annotation: Subtype: Link Rect: 130, 688, 142, 698 ActionDest: 47 Annotation: Subtype: Link Rect: 328, 688, 340, 698 ActionDest: 47 Annotation: Subtype: Link Rect: 371, 648, 383, 657 ActionDest: 41 Annotation: Subtype: Link Rect: 181, 621, 193, 630 ActionDest: 41 Annotation: Subtype: Link Rect: 428, 621, 440, 630 ActionDest: 41 Annotation: Subtype: Link Rect: 503, 594, 515, 603 ActionDest: 47 Annotation: Subtype: Link Rect: 102, 553, 114, 562 ActionDest: 47 Annotation: Subtype: Link Rect: 312, 553, 324, 562 ActionDest: 41 Annotation: Subtype: Link Rect: 407, 540, 419, 549 ActionDest: 47 Annotation: Subtype: Link Rect: 91, 526, 103, 535 ActionDest: 41 Annotation: Subtype: Link Rect: 402, 526, 414, 535 ActionDest: 47 Annotation: Subtype: Link Rect: 414, 526, 426, 535 ActionDest: 47 Annotation: Subtype: Link Rect: 448, 499, 460, 508 ActionDest: 47 Annotation: Subtype: Link Rect: 503, 486, 515, 495 ActionDest: 47 Annotation: Subtype: Link Rect: 201, 472, 213, 481 ActionDest: 47 Annotation: Subtype: Link Rect: 410, 445, 422, 454 ActionDest: 47 Annotation: Subtype: Link Rect: 333, 405, 345, 414 ActionDest: 41 Annotation: Subtype: Link Rect: 139, 378, 151, 387 ActionDest: 47 Annotation: Subtype: Link Rect: 179, 337, 191, 346 ActionDest: 47 Annotation: Subtype: Link Rect: 363, 310, 375, 319 ActionDest: 47 Annotation: Subtype: Link Rect: 210, 283, 222, 292 ActionDest: 41 Annotation: Subtype: Link Rect: 419, 256, 431, 265 ActionDest: 41 Annotation: Subtype: Link Rect: 503, 242, 515, 252 ActionDest: 47 Annotation: Subtype: Link Rect: 304, 215, 316, 225 ActionDest: 41 Annotation: Subtype: Link Rect: 197, 188, 208, 198 ActionDest: 41 Annotation: Subtype: Link Rect: 367, 161, 379, 171 ActionDest: 41 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 96, 301, 194, 312 Annotation: Subtype: Link Rect: 263, 276, 300, 286 Annotation: Subtype: Link Rect: 228, 250, 265, 260 Annotation: Subtype: Link Rect: 272, 250, 308, 260 Annotation: Subtype: Link Rect: 427, 223, 464, 234 Annotation: Subtype: Link Rect: 470, 223, 506, 234 Annotation: Subtype: Link Rect: 368, 197, 406, 208 Annotation: Subtype: Link Rect: 100, 173, 137, 183 Annotation: Subtype: Link Rect: 232, 133, 270, 144 Annotation: Subtype: Link Rect: 276, 133, 312, 144 Annotation: Subtype: Link Rect: 172, 108, 209, 118 Annotation: Subtype: Link Rect: 215, 108, 251, 118 Annotation: Subtype: Link Rect: 136, 82, 174, 92 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 127, 715, 165, 725 Annotation: Subtype: Link Rect: 219, 688, 257, 699 Annotation: Subtype: Link Rect: 154, 638, 192, 648 Annotation: Subtype: Link Rect: 198, 638, 234, 648 Annotation: Subtype: Link Rect: 472, 611, 509, 622 Annotation: Subtype: Link Rect: 479, 559, 516, 570 Annotation: Subtype: Link Rect: 100, 547, 136, 557 Annotation: Subtype: Link Rect: 145, 508, 182, 519 Annotation: Subtype: Link Rect: 257, 470, 294, 480 Annotation: Subtype: Link Rect: 256, 430, 293, 441 Annotation: Subtype: Link Rect: 299, 430, 335, 441 Annotation: Subtype: Link Rect: 324, 353, 362, 364 Annotation: Subtype: Link Rect: 234, 263, 272, 273 Annotation: Subtype: Link Rect: 100, 212, 137, 222 Annotation: Subtype: Link Rect: 143, 212, 179, 222 Annotation: Subtype: Link Rect: 434, 198, 508, 209 Annotation: Subtype: Link Rect: 215, 173, 253, 183 Annotation: Subtype: Link Rect: 409, 134, 447, 144 Annotation: Subtype: Link Rect: 338, 107, 376, 118 Annotation: Subtype: Link Rect: 382, 107, 418, 118 Annotation: Subtype: Link Rect: 354, 82, 392, 92 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 402, 728, 439, 738 Annotation: Subtype: Link Rect: 452, 701, 489, 712 Annotation: Subtype: Link Rect: 480, 675, 516, 686 Annotation: Subtype: Link Rect: 100, 547, 137, 557 Annotation: Subtype: Link Rect: 297, 353, 335, 364 Annotation: Subtype: Link Rect: 280, 328, 317, 338 Annotation: Subtype: Link Rect: 432, 301, 470, 312 Annotation: Subtype: Link Rect: 349, 262, 387, 273 Annotation: Subtype: Link Rect: 381, 236, 418, 247 Annotation: Subtype: Link Rect: 150, 199, 187, 209 Annotation: Subtype: Link Rect: 453, 172, 490, 183 Annotation: Subtype: Link Rect: 382, 146, 419, 157 Annotation: Subtype: Link Rect: 430, 107, 468, 118 Annotation: Subtype: Link Rect: 474, 107, 510, 118 Annotation: Subtype: Link Rect: 479, 82, 516, 92 Annotation: Subtype: Link Rect: 100, 69, 136, 80 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 336, 727, 374, 738 Annotation: Subtype: Link Rect: 427, 701, 464, 712 Annotation: Subtype: Link Rect: 470, 701, 506, 712 Annotation: Subtype: Link Rect: 358, 663, 395, 673 Annotation: Subtype: Link Rect: 168, 638, 205, 648 Annotation: Subtype: Link Rect: 411, 611, 449, 622 Annotation: Subtype: Link Rect: 441, 585, 479, 596 Annotation: Subtype: Link Rect: 314, 559, 352, 570 Annotation: Subtype: Link Rect: 278, 521, 316, 531 Annotation: Subtype: Link Rect: 386, 456, 424, 467 Annotation: Subtype: Link Rect: 286, 430, 323, 441 Annotation: Subtype: Link Rect: 460, 404, 497, 415 Annotation: Subtype: Link Rect: 455, 378, 493, 389 Annotation: Subtype: Link Rect: 136, 354, 174, 364 Annotation: Subtype: Link Rect: 154, 328, 191, 338 Annotation: Subtype: Link Rect: 330, 301, 368, 312 Annotation: Subtype: Link Rect: 141, 263, 178, 273 Annotation: Subtype: Link Rect: 76, 221, 166, 252 Annotation: Subtype: Link Rect: 234, 215, 407, 226 Checksum: 525682c1 Type: CRC32 Checksum: bfcdec2cebebd3be226461b8170650de Type: MD5 Checksum: 1daec66123b94cadb901b5fa8df6e8dd346f7431 Type: SHA-1 Checksum: 3e98042042af62df1a9ee04c2b012876e89b47328314e3f051919e35f00faffe Type: SHA-256