f4a7c25e4485370e48dd778dedace74b nutrients_a2019v11p2616.pdf 75e1fdb2ed6705bf6c34d2077c2552a9adca944e nutrients_a2019v11p2616.pdf 51d43e89952d74625f9f63e54b080402872674b40696f5a0ffac0aad440507c4 nutrients_a2019v11p2616.pdf Title: Intra-Abdominal Pressure as a Marker of Enteral Nutrition Intolerance in Critically Ill Patients. The PIANE Study Subject: To determine whether elevated intra-abdominal pressure (IAP) is associated with a higher rate of enteral nutrition-related gastrointestinal (GI) complications; to assess the value of IAP as a predictor of enteral nutrition (EN) intolerance. Intensive Care Unit (ICU) patients on mechanical ventilation requiring at least 5 days of EN were recruited for a prospective, observational, non-interventional, multicenter study. EN was performed and GI complications were managed with an established protocol. IAP was determined via a urinary catheter. Patients who developed any GI complications were considered as presenting EN intolerance. Variables related to EN, IAP and GI complications were monitored daily. Statistical analysis compared patients without GI complications (group A) vs. GI complications (group B). 247 patients were recruited from 28 participating ICUs (group A: 119, group B: 128). No differences between groups were recorded. Patients in group B (p < 0.001) spent more days on EN (8.1 8.4 vs. 18.1 13.7), on mechanical ventilation (8.0 7.7 vs. 19.3 14.9) and in the ICU (12.3 11.4 vs. 24.8 17.5). IAP prior to the GI complication was (14.3 3.1 vs. 15.8 4.8) (p < 0.003). The best IAP value identified for EN intolerance was 14 mmHg but it had low sensitivity and specificity. Although a higher IAP was associated with EN intolerance, IAP alone did not emerge as a good predictor of EN intolerance in critically ill patients. Keywords: enteral nutrition; enteral nutrition intolerance; gastrointestinal complications; intensive care unit; intra-abdominal pressure Author: M Luisa Bordejé, Juan C. Montejo, M Lidón Mateu, Manuel Solera, Jose A. Acosta, Mar Juan, Francisco García-Córdoba, Miguel A. García-Martínez, Rosa Gastaldo and PIANE STUDY GROUP SPAIN Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.18 CreationDate: Fri Nov 1 11:19:30 2019 CET ModDate: Fri Nov 1 11:19:30 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1069678 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AAVZQZ+URWPalladioL-Ital Type 1 Custom yes yes no 60 0 VARYVF+URWPalladioL-Bold Type 1 Custom yes yes no 61 0 XWOCXD+VnURWPalladioL-Bold Type 1 Custom yes yes no 62 0 QTLELQ+Pxbsy Type 1 Builtin yes yes no 63 0 FLGRYX+URWPalladioL-Roma Type 1 Custom yes yes no 64 0 WDLIVJ+Rpxr Type 1 Builtin yes yes no 65 0 HKBJPQ+VnURWPalladioL Type 1 Custom yes yes no 66 0 VVUSKL+Pxsy Type 1 Builtin yes yes no 67 0 HGMNRX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 72 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 89 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 90 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 91 0 TGMEOR+Rpcxr Type 1 Builtin yes yes no 144 0 QDCWHF+EURM10 Type 1 Builtin yes yes no 145 0 QLBIEB+URWPalladioL-BoldItal Type 1 Custom yes yes no 155 0 VUPETJ+Rpxb Type 1 Builtin yes yes no 156 0 AEFINP+PalatinoLinotype TrueType WinAnsi yes yes no 171 0 AEFIPB+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 172 0 AEFIPD+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 173 0 AEFJLA+TimesNewRoman CID TrueType Identity-H yes yes yes 174 0 AEFINP+PalatinoLinotype TrueType WinAnsi yes yes no 204 0 AEFIPB+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 205 0 AEFIPD+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 206 0 AEFJLA+TimesNewRoman CID TrueType Identity-H yes yes yes 207 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-01-30 05:23:30 CET RepresentationInformation: nutrients_a2019v11p2616.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-01-14 10:41:14 CET Size: 1069678 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: ぉのぴひはつふっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸲ Item: Title: きちぴづひどちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮ㄩ‾㸊⡜㌷㙜㌷㝜〰ざちひどちぢぬづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Children: Item: Title: ざちひどちぢぬづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: こぴちぴどびぴどっちぬぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: げづびふぬぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸴ Item: Title: いどびっふびびどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸵ Item: Title: ぃはのっぬふびどはのびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸵ Item: Title: げづてづひづのっづび Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: FLGRYX+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 246 FontDescriptor: FontName: FLGRYX+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TGMEOR+Rpcxr FontSubset: true FirstChar: 169 LastChar: 174 FontDescriptor: FontName: TGMEOR+Rpcxr Flags: Symbolic FontBBox: -212, -286, 1344, 973 FontFile: true Font: BaseFont: WDLIVJ+Rpxr FontSubset: true FirstChar: 11 LastChar: 62 FontDescriptor: FontName: WDLIVJ+Rpxr Flags: Symbolic FontBBox: -40, -283, 904, 728 FontFile: true Font: BaseFont: QDCWHF+EURM10 FontSubset: true FirstChar: 11 LastChar: 12 FontDescriptor: FontName: QDCWHF+EURM10 Flags: Symbolic FontBBox: -32, -243, 1060, 720 FontFile: true Font: BaseFont: HKBJPQ+VnURWPalladioL FontSubset: true FirstChar: 129 LastChar: 226 FontDescriptor: FontName: HKBJPQ+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VVUSKL+Pxsy FontSubset: true FirstChar: 2 LastChar: 121 FontDescriptor: FontName: VVUSKL+Pxsy Flags: Symbolic FontBBox: -21, -994, 1292, 912 FontFile: true Font: BaseFont: QLBIEB+URWPalladioL-BoldItal FontSubset: true FirstChar: 110 LastChar: 112 FontDescriptor: FontName: QLBIEB+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: AAVZQZ+URWPalladioL-Ital FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: AAVZQZ+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VUPETJ+Rpxb FontSubset: true FirstChar: 61 LastChar: 61 FontDescriptor: FontName: VUPETJ+Rpxb Flags: Symbolic FontBBox: -57, -266, 932, 729 FontFile: true Font: BaseFont: VARYVF+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 122 FontDescriptor: FontName: VARYVF+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XWOCXD+VnURWPalladioL-Bold FontSubset: true FirstChar: 178 LastChar: 226 FontDescriptor: FontName: XWOCXD+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: QTLELQ+Pxbsy FontSubset: true FirstChar: 121 LastChar: 121 FontDescriptor: FontName: QTLELQ+Pxbsy Flags: Symbolic FontBBox: 5, -978, 1382, 913 FontFile: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 75, 757, 210, 793 Annotation: Subtype: Link Rect: 474, 757, 519, 793 Annotation: Subtype: Link Rect: 257, 640, 268, 654 Annotation: Subtype: Link Rect: 349, 640, 360, 654 Annotation: Subtype: Link Rect: 466, 377, 518, 396 Annotation: Subtype: Link Rect: 174, 38, 246, 50 Annotation: Subtype: Link Rect: 398, 38, 519, 50 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 489, 723, 496, 732 ActionDest: 254 Annotation: Subtype: Link Rect: 508, 710, 515, 719 ActionDest: 254 Annotation: Subtype: Link Rect: 463, 696, 470, 705 ActionDest: 281 Annotation: Subtype: Link Rect: 471, 696, 478, 705 ActionDest: 281 Annotation: Subtype: Link Rect: 365, 669, 372, 678 ActionDest: 281 Annotation: Subtype: Link Rect: 452, 655, 459, 665 ActionDest: 281 Annotation: Subtype: Link Rect: 460, 655, 467, 665 ActionDest: 281 Annotation: Subtype: Link Rect: 164, 601, 171, 611 ActionDest: 281 Annotation: Subtype: Link Rect: 417, 588, 424, 597 ActionDest: 281 Annotation: Subtype: Link Rect: 138, 561, 145, 570 ActionDest: 254 Annotation: Subtype: Link Rect: 146, 561, 153, 570 ActionDest: 281 Annotation: Subtype: Link Rect: 153, 561, 165, 570 ActionDest: 281 Annotation: Subtype: Link Rect: 488, 520, 500, 529 ActionDest: 281 Annotation: Subtype: Link Rect: 503, 520, 515, 529 ActionDest: 281 Annotation: Subtype: Link Rect: 130, 493, 142, 502 ActionDest: 281 Annotation: Subtype: Link Rect: 145, 493, 157, 502 ActionDest: 281 Annotation: Subtype: Link Rect: 358, 480, 370, 489 ActionDest: 311 Annotation: Subtype: Link Rect: 371, 480, 383, 489 ActionDest: 311 Annotation: Subtype: Link Rect: 503, 261, 515, 271 ActionDest: 311 Annotation: Subtype: Link Rect: 500, 126, 507, 136 ActionDest: 281 Annotation: Subtype: Link Rect: 508, 126, 515, 136 ActionDest: 281 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 427, 675, 434, 684 ActionDest: 281 Annotation: Subtype: Link Rect: 434, 675, 441, 684 ActionDest: 281 Annotation: Subtype: Link Rect: 168, 634, 180, 644 ActionDest: 311 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 326, 543, 333, 554 ActionDest: 151 Annotation: Subtype: Link Rect: 508, 475, 515, 487 ActionDest: 151 Annotation: Subtype: Link Rect: 104, 69, 111, 80 ActionDest: 165 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 237, 538, 244, 550 ActionDest: 151 Annotation: Subtype: Link Rect: 287, 525, 294, 537 ActionDest: 199 Annotation: Subtype: Link Rect: 508, 457, 515, 469 ActionDest: 165 Annotation: Subtype: Link Rect: 490, 430, 497, 442 ActionDest: 199 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 237, 242, 249, 251 ActionDest: 311 Annotation: Subtype: Link Rect: 417, 201, 429, 210 ActionDest: 311 Annotation: Subtype: Link Rect: 429, 201, 441, 210 ActionDest: 311 Annotation: Subtype: Link Rect: 165, 188, 177, 197 ActionDest: 311 Annotation: Subtype: Link Rect: 184, 93, 196, 102 ActionDest: 311 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 258, 702, 270, 711 ActionDest: 311 Annotation: Subtype: Link Rect: 256, 675, 268, 684 ActionDest: 311 Annotation: Subtype: Link Rect: 141, 634, 153, 644 ActionDest: 311 Annotation: Subtype: Link Rect: 440, 551, 447, 562 ActionDest: 199 Annotation: Subtype: Link Rect: 339, 540, 351, 549 ActionDest: 281 Annotation: Subtype: Link Rect: 130, 486, 142, 495 ActionDest: 281 Annotation: Subtype: Link Rect: 296, 445, 308, 454 ActionDest: 311 Annotation: Subtype: Link Rect: 311, 445, 323, 454 ActionDest: 311 Annotation: Subtype: Link Rect: 263, 324, 270, 333 ActionDest: 281 Annotation: Subtype: Link Rect: 113, 310, 120, 319 ActionDest: 281 Annotation: Subtype: Link Rect: 171, 270, 178, 279 ActionDest: 281 Annotation: Subtype: Link Rect: 199, 215, 211, 225 ActionDest: 311 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 138, 729, 150, 738 ActionDest: 311 Annotation: Subtype: Link Rect: 163, 99, 201, 109 Annotation: Subtype: Link Rect: 207, 99, 243, 109 Annotation: Subtype: Link Rect: 265, 72, 303, 83 Annotation: Subtype: Link Rect: 309, 72, 345, 83 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 277, 714, 314, 725 Annotation: Subtype: Link Rect: 321, 714, 357, 725 Annotation: Subtype: Link Rect: 181, 689, 219, 699 Annotation: Subtype: Link Rect: 225, 689, 261, 699 Annotation: Subtype: Link Rect: 442, 650, 480, 661 Annotation: Subtype: Link Rect: 317, 611, 355, 622 Annotation: Subtype: Link Rect: 145, 573, 182, 583 Annotation: Subtype: Link Rect: 325, 533, 363, 544 Annotation: Subtype: Link Rect: 193, 508, 231, 519 Annotation: Subtype: Link Rect: 177, 457, 214, 467 Annotation: Subtype: Link Rect: 249, 431, 286, 441 Annotation: Subtype: Link Rect: 292, 431, 328, 441 Annotation: Subtype: Link Rect: 181, 379, 219, 389 Annotation: Subtype: Link Rect: 225, 379, 261, 389 Annotation: Subtype: Link Rect: 136, 354, 174, 364 Annotation: Subtype: Link Rect: 180, 354, 216, 364 Annotation: Subtype: Link Rect: 163, 315, 201, 325 Annotation: Subtype: Link Rect: 207, 315, 243, 325 Annotation: Subtype: Link Rect: 318, 288, 355, 299 Annotation: Subtype: Link Rect: 366, 236, 403, 247 Annotation: Subtype: Link Rect: 453, 185, 490, 196 Annotation: Subtype: Link Rect: 340, 82, 377, 92 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 326, 727, 364, 738 Annotation: Subtype: Link Rect: 370, 727, 406, 738 Annotation: Subtype: Link Rect: 310, 701, 347, 712 Annotation: Subtype: Link Rect: 354, 701, 390, 712 Annotation: Subtype: Link Rect: 100, 612, 137, 622 Annotation: Subtype: Link Rect: 143, 612, 179, 622 Annotation: Subtype: Link Rect: 404, 585, 442, 596 Annotation: Subtype: Link Rect: 448, 585, 484, 596 Annotation: Subtype: Link Rect: 409, 533, 446, 544 Annotation: Subtype: Link Rect: 136, 483, 174, 493 Annotation: Subtype: Link Rect: 100, 444, 137, 454 Annotation: Subtype: Link Rect: 159, 379, 196, 389 Annotation: Subtype: Link Rect: 137, 328, 175, 338 Annotation: Subtype: Link Rect: 181, 328, 217, 338 Annotation: Subtype: Link Rect: 100, 263, 136, 273 Annotation: Subtype: Link Rect: 437, 224, 474, 234 Annotation: Subtype: Link Rect: 481, 224, 516, 234 Annotation: Subtype: Link Rect: 100, 173, 137, 183 Annotation: Subtype: Link Rect: 76, 131, 166, 162 Annotation: Subtype: Link Rect: 234, 125, 407, 136 Checksum: 00026827 Type: CRC32 Checksum: f4a7c25e4485370e48dd778dedace74b Type: MD5 Checksum: 75e1fdb2ed6705bf6c34d2077c2552a9adca944e Type: SHA-1