5a4b29ee49df6fb31ec9ce07469f2c34 pdf_222721.pdf 141787e98fb7c6bd9b78ba32246edf330b8d8081 pdf_222721.pdf ba7af8b842c2c3b369b27dd56bfde5dd4c422e9acf938567128c431200b6bf43 pdf_222721.pdf Title: Lifetime risk of knee and hip replacement following a GP diagnosis of osteoarthritis: a real-world cohort study Subject: Osteoarthritis and Cartilage, 27 (2019) 1627-1635. doi:10.1016/j.joca.2019.06.004 Author: E. Burn Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Oct 15 21:25:13 2019 CEST ModDate: Wed May 19 12:48:56 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 854663 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DBDPCH+AdvOT863180fb Type 1C WinAnsi yes yes no 571 0 DBDPDP+AdvOTb83ee1dd.B Type 1C WinAnsi yes yes no 573 0 DBDPCI+AdvP4C4E74 Type 1C Custom yes yes yes 576 0 DBDPCJ+AdvTT5843c571 Type 1C WinAnsi yes yes no 578 0 DBDPCK+AdvOTb92eb7df.I Type 1C WinAnsi yes yes no 580 0 DBDPCL+AdvOTb92eb7df.I+fb Type 1C Custom yes yes yes 583 0 DBDPCM+AdvOTc4d0b532 Type 1C WinAnsi yes yes no 585 0 DBDPDM+AdvOT863180fb+fb Type 1C Custom yes yes yes 588 0 DBDPDN+AdvPS44A44B Type 1C WinAnsi yes yes no 590 0 DBDPDO+AdvOTb0c9bf5d Type 1C WinAnsi yes yes no 592 0 DBDPIO+AdvOTb92eb7df.I+20 Type 1C WinAnsi yes yes no 302 0 DBDPIP+AdvP4C4E59 Type 1C Custom yes yes yes 300 0 DBDPJA+AdvOT863180fb+20 Type 1C WinAnsi yes yes no 301 0 DBEBEH+AdvOTb83ee1dd.B+fb Type 1C Custom yes yes yes 309 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-05-20 02:32:46 CEST RepresentationInformation: pdf_222721.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-05-19 12:50:29 CEST Size: 854663 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib10' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib12' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib18' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib19' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib20' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib21' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib22' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'sec3' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib24' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib25' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib26' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib27' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib27' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib30' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib32' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib10' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib33' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib34' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib35' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib36' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib36' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib40' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib41' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib27' cannot be found Offset: 845502 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 845502 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Lifetime risk of knee and hip replacement following a GP diagnosis of osteoarthritis: a real-world cohort study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Children: Item: Title: Setting Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Study participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Participant characteristics at diagnosis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Statistical methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Children: Item: Title: Comparison of cumulative incidence of knee/hip replacement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Estimating parametric survival models for risks of knee/hip replacement and mortality Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Estimating lifetime risk Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Children: Item: Title: Study participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Observed risks of knee/hip replacement and mortality Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Average lifetime risks of knee and hip replacement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Participant characteristics and lifetime risks of knee/hip replacement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Children: Item: Title: Study findings in context Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: Strengths and limitations of this study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Contributors Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Conflict of interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: Ethical approval Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Item: Title: Data sharing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca Item: Title: Transparency Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Item: Title: Appendix A. Supplementary data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 120 ImageHeight: 119 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2167 ImageHeight: 240 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 701 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 701 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 1174 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 683 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: DBDPCI+AdvP4C4E74 FontSubset: true FirstChar: 2 LastChar: 254 FontDescriptor: FontName: DBDPCI+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DBDPCJ+AdvTT5843c571 FontSubset: true FirstChar: 38 LastChar: 182 FontDescriptor: FontName: DBDPCJ+AdvTT5843c571 Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPCK+AdvOTb92eb7df.I FontSubset: true FirstChar: 39 LastChar: 237 FontDescriptor: FontName: DBDPCK+AdvOTb92eb7df.I Flags: Serif, Nonsymbolic FontBBox: -135, -229, 1052, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPCL+AdvOTb92eb7df.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DBDPCL+AdvOTb92eb7df.I+fb Flags: Symbolic FontBBox: -114, -208, 833, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DBDPCM+AdvOTc4d0b532 FontSubset: true FirstChar: 97 LastChar: 121 FontDescriptor: FontName: DBDPCM+AdvOTc4d0b532 Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPDM+AdvOT863180fb+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: DBDPDM+AdvOT863180fb+fb Flags: Symbolic FontBBox: 40, 0, 895, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DBDPIP+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 126 FontDescriptor: FontName: DBDPIP+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DBDPJA+AdvOT863180fb+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: DBDPJA+AdvOT863180fb+20 Flags: Nonsymbolic FontBBox: 9, -208, 947, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPDN+AdvPS44A44B FontSubset: true FirstChar: 100 LastChar: 101 FontDescriptor: FontName: DBDPDN+AdvPS44A44B Flags: Nonsymbolic FontBBox: 0, -197, 1000, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPIO+AdvOTb92eb7df.I+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: DBDPIO+AdvOTb92eb7df.I+20 Flags: Nonsymbolic FontBBox: -41, -208, 885, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPDO+AdvOTb0c9bf5d FontSubset: true FirstChar: 60 LastChar: 169 FontDescriptor: FontName: DBDPDO+AdvOTb0c9bf5d Flags: Nonsymbolic FontBBox: -62, -208, 927, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBEBEH+AdvOTb83ee1dd.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DBEBEH+AdvOTb83ee1dd.B+fb Flags: Symbolic FontBBox: 19, 0, 947, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DBDPCH+AdvOT863180fb FontSubset: true FirstChar: 35 LastChar: 237 FontDescriptor: FontName: DBDPCH+AdvOT863180fb Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DBDPDP+AdvOTb83ee1dd.B FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: DBDPDP+AdvOTb83ee1dd.B Flags: Nonsymbolic FontBBox: -93, -250, 1041, 989 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.joca.2019.06.004 Lifetime risk of knee and hip replacement following a GP diagnosis of osteoarthritis: a real-world cohort study E. Burn D.W. Murray G.A. Hawker R. Pinedo-Villanueva D. Prieto-Alhambra Osteoarthritis Orthopedic surgery Epidemiology Osteoarthritis and Cartilage, 27 (2019) 1627-1635. doi:10.1016/j.joca.2019.06.004 Elsevier Ltd journal Osteoarthritis and Cartilage © 2019 The Authors. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International. 1063-4584 27 11 November 2019 1627-1635 1627 1635 10.1016/j.joca.2019.06.004 https://doi.org/10.1016/j.joca.2019.06.004 2010-04-23 true 10.1016/j.joca.2019.06.004 elsevier.com sciencedirect.com VoR 6.5 10.1016/j.joca.2019.06.004 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2019-10-16T00:55:13+05:30 2021-05-19T12:48:56+02:00 2021-05-19T12:48:56+02:00 True Acrobat Distiller 8.1.0 (Windows) uuid:d4610fb0-4f39-4846-ab48-b711ba878122 uuid:1adccf40-0780-4066-aa29-846dc4e31a61 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1627 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 250, 562, 255, 573 Destination: 485 Annotation: Subtype: Link Rect: 375, 570, 380, 575 Destination: 485 Annotation: Subtype: Link Rect: 149, 549, 156, 560 Destination: 485 Annotation: Subtype: Link Rect: 424, 258, 562, 265 Annotation: Subtype: Link Rect: 522, 249, 558, 256 Annotation: Subtype: Link Rect: 95, 161, 99, 169 Destination: 23 Annotation: Subtype: Link Rect: 557, 203, 560, 211 Destination: 23 Annotation: Subtype: Link Rect: 541, 182, 549, 190 Destination: 23 Annotation: Subtype: Link Rect: 342, 140, 345, 148 Destination: 23 Annotation: Subtype: Link Rect: 348, 108, 352, 116 Destination: 23 Annotation: Subtype: Link Rect: 457, 98, 461, 106 Destination: 23 Annotation: Subtype: Link Rect: 473, 88, 477, 96 Destination: 23 Annotation: Subtype: Link Rect: 101, 77, 195, 83 Annotation: Subtype: Link Rect: 534, 586, 562, 615 Annotation: Subtype: Link Rect: 42, 58, 167, 65 Annotation: Subtype: Link Rect: 67, 41, 222, 48 Annotation: Subtype: Link Rect: 229, 739, 356, 745 Annotation: Subtype: Link Rect: 361, 739, 375, 745 Page: Label: 1628 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 279, 712, 282, 720 Destination: 23 Annotation: Subtype: Link Rect: 63, 670, 66, 678 Destination: 23 Annotation: Subtype: Link Rect: 149, 659, 156, 667 Destination: null Annotation: Subtype: Link Rect: 141, 618, 147, 626 Destination: null Annotation: Subtype: Link Rect: 258, 597, 265, 605 Destination: null Annotation: Subtype: Link Rect: 239, 586, 246, 594 Destination: null Annotation: Subtype: Link Rect: 221, 384, 280, 392 Annotation: Subtype: Link Rect: 202, 356, 209, 364 Destination: null Annotation: Subtype: Link Rect: 122, 346, 129, 354 Destination: null Annotation: Subtype: Link Rect: 197, 199, 204, 207 Destination: null Annotation: Subtype: Link Rect: 129, 178, 135, 186 Destination: null Annotation: Subtype: Link Rect: 414, 722, 421, 730 Destination: null Annotation: Subtype: Link Rect: 354, 680, 361, 688 Destination: null Annotation: Subtype: Link Rect: 399, 659, 406, 667 Destination: null Annotation: Subtype: Link Rect: 458, 450, 465, 458 Destination: null Annotation: Subtype: Link Rect: 323, 272, 330, 280 Destination: null Annotation: Subtype: Link Rect: 543, 147, 550, 155 Destination: null Annotation: Subtype: Link Rect: 359, 122, 364, 130 Destination: null Annotation: Subtype: Link Rect: 301, 112, 340, 120 Destination: null Page: Label: 1629 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 113, 712, 120, 720 Destination: null Annotation: Subtype: Link Rect: 282, 680, 289, 688 Destination: null Annotation: Subtype: Link Rect: 114, 398, 121, 406 Destination: null Annotation: Subtype: Link Rect: 134, 164, 162, 172 Destination: null Annotation: Subtype: Link Rect: 152, 154, 176, 162 Destination: 7 Annotation: Subtype: Link Rect: 244, 112, 276, 120 Destination: null Annotation: Subtype: Link Rect: 264, 101, 293, 109 Destination: null Annotation: Subtype: Link Rect: 42, 91, 69, 99 Destination: null Annotation: Subtype: Link Rect: 42, 49, 101, 57 Destination: null Annotation: Subtype: Link Rect: 466, 666, 493, 674 Destination: 10 Annotation: Subtype: Link Rect: 496, 583, 560, 591 Destination: null Annotation: Subtype: Link Rect: 350, 562, 415, 570 Destination: null Annotation: Subtype: Link Rect: 353, 436, 373, 444 Destination: 10 Annotation: Subtype: Link Rect: 353, 332, 373, 340 Destination: 14 Annotation: Subtype: Link Rect: 421, 216, 442, 224 Destination: 14 Annotation: Subtype: Link Rect: 419, 206, 439, 214 Destination: 19 Annotation: Subtype: Link Rect: 403, 112, 460, 120 Destination: null Page: Label: 1630 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 83, 157, 86, 165 Destination: 23 Annotation: Subtype: Link Rect: 91, 157, 97, 165 Destination: 23 Annotation: Subtype: Link Rect: 73, 126, 80, 134 Destination: null Annotation: Subtype: Link Rect: 85, 126, 92, 134 Destination: null Annotation: Subtype: Link Rect: 101, 95, 108, 102 Destination: null Annotation: Subtype: Link Rect: 422, 294, 426, 302 Destination: 23 Annotation: Subtype: Link Rect: 433, 105, 440, 113 Destination: null Annotation: Subtype: Link Rect: 492, 84, 499, 92 Destination: null Page: Label: 1631 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 162, 314, 169, 322 Destination: null Annotation: Subtype: Link Rect: 428, 324, 435, 332 Destination: null Annotation: Subtype: Link Rect: 449, 303, 456, 311 Destination: null Annotation: Subtype: Link Rect: 340, 272, 347, 280 Destination: null Page: Label: 1632 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 242, 371, 249, 379 Destination: null Annotation: Subtype: Link Rect: 164, 361, 172, 369 Destination: null Annotation: Subtype: Link Rect: 176, 361, 183, 369 Destination: null Annotation: Subtype: Link Rect: 274, 350, 281, 358 Destination: null Annotation: Subtype: Link Rect: 227, 319, 234, 327 Destination: null Annotation: Subtype: Link Rect: 149, 267, 156, 275 Destination: null Page: Label: 1633 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 164, 520, 179, 528 Destination: null Annotation: Subtype: Link Rect: 265, 353, 280, 361 Destination: null Annotation: Subtype: Link Rect: 311, 363, 439, 371 Page: Label: 1634 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 32, 519, 188, 527 Annotation: Subtype: Link Rect: 226, 457, 283, 465 Annotation: Subtype: Link Rect: 47, 447, 170, 455 Annotation: Subtype: Link Rect: 193, 394, 283, 402 Annotation: Subtype: Link Rect: 47, 384, 115, 392 Annotation: Subtype: Link Rect: 193, 363, 283, 371 Annotation: Subtype: Link Rect: 47, 352, 140, 360 Annotation: Subtype: Link Rect: 47, 321, 230, 329 Annotation: Subtype: Link Rect: 47, 269, 213, 277 Annotation: Subtype: Link Rect: 73, 227, 230, 235 Annotation: Subtype: Link Rect: 193, 175, 283, 183 Annotation: Subtype: Link Rect: 47, 164, 115, 172 Annotation: Subtype: Link Rect: 193, 122, 283, 130 Annotation: Subtype: Link Rect: 47, 112, 123, 120 Annotation: Subtype: Link Rect: 132, 70, 258, 78 Annotation: Subtype: Link Rect: 462, 708, 552, 716 Annotation: Subtype: Link Rect: 317, 698, 353, 706 Annotation: Subtype: Link Rect: 356, 645, 527, 653 Annotation: Subtype: Link Rect: 317, 635, 552, 643 Annotation: Subtype: Link Rect: 317, 624, 552, 632 Annotation: Subtype: Link Rect: 317, 614, 552, 622 Annotation: Subtype: Link Rect: 317, 604, 371, 612 Annotation: Subtype: Link Rect: 377, 604, 387, 612 Annotation: Subtype: Link Rect: 462, 562, 552, 570 Annotation: Subtype: Link Rect: 317, 551, 400, 559 Annotation: Subtype: Link Rect: 439, 499, 552, 507 Annotation: Subtype: Link Rect: 317, 488, 389, 496 Annotation: Subtype: Link Rect: 394, 436, 525, 444 Annotation: Subtype: Link Rect: 495, 384, 552, 392 Annotation: Subtype: Link Rect: 317, 373, 454, 381 Annotation: Subtype: Link Rect: 408, 321, 552, 329 Annotation: Subtype: Link Rect: 317, 311, 363, 319 Annotation: Subtype: Link Rect: 317, 269, 496, 277 Annotation: Subtype: Link Rect: 524, 227, 552, 235 Annotation: Subtype: Link Rect: 317, 216, 417, 224 Annotation: Subtype: Link Rect: 525, 175, 552, 183 Annotation: Subtype: Link Rect: 317, 164, 443, 172 Annotation: Subtype: Link Rect: 452, 154, 552, 162 Annotation: Subtype: Link Rect: 317, 143, 552, 151 Annotation: Subtype: Link Rect: 317, 133, 439, 141 Annotation: Subtype: Link Rect: 462, 101, 552, 109 Annotation: Subtype: Link Rect: 317, 91, 432, 99 Page: Label: 1635 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 203, 719, 293, 727 Annotation: Subtype: Link Rect: 57, 708, 134, 716 Annotation: Subtype: Link Rect: 57, 677, 210, 685 Annotation: Subtype: Link Rect: 177, 656, 293, 664 Annotation: Subtype: Link Rect: 57, 645, 107, 653 Annotation: Subtype: Link Rect: 269, 635, 293, 643 Annotation: Subtype: Link Rect: 57, 624, 173, 632 Annotation: Subtype: Link Rect: 180, 624, 255, 632 Annotation: Subtype: Link Rect: 64, 614, 76, 622 Annotation: Subtype: Link Rect: 82, 614, 117, 622 Annotation: Subtype: Link Rect: 123, 614, 140, 622 Annotation: Subtype: Link Rect: 147, 614, 170, 622 Annotation: Subtype: Link Rect: 177, 614, 181, 622 Annotation: Subtype: Link Rect: 187, 614, 192, 622 Annotation: Subtype: Link Rect: 203, 562, 293, 570 Annotation: Subtype: Link Rect: 57, 551, 94, 559 Annotation: Subtype: Link Rect: 265, 499, 293, 507 Annotation: Subtype: Link Rect: 57, 488, 188, 496 Annotation: Subtype: Link Rect: 236, 447, 293, 455 Annotation: Subtype: Link Rect: 57, 436, 159, 444 Annotation: Subtype: Link Rect: 203, 384, 293, 392 Annotation: Subtype: Link Rect: 57, 373, 94, 381 Annotation: Subtype: Link Rect: 203, 332, 293, 340 Annotation: Subtype: Link Rect: 57, 321, 94, 329 Annotation: Subtype: Link Rect: 236, 290, 293, 298 Annotation: Subtype: Link Rect: 57, 279, 130, 287 Annotation: Subtype: Link Rect: 236, 248, 293, 256 Annotation: Subtype: Link Rect: 57, 237, 166, 245 Annotation: Subtype: Link Rect: 406, 687, 545, 695 Annotation: Subtype: Link Rect: 396, 645, 562, 653 Annotation: Subtype: Link Rect: 326, 635, 453, 643 Annotation: Subtype: Link Rect: 423, 593, 562, 601 Annotation: Subtype: Link Rect: 326, 583, 353, 591 Annotation: Subtype: Link Rect: 472, 551, 562, 559 Annotation: Subtype: Link Rect: 326, 541, 363, 549 Annotation: Subtype: Link Rect: 441, 499, 562, 507 Annotation: Subtype: Link Rect: 326, 488, 371, 496 Annotation: Subtype: Link Rect: 472, 447, 562, 455 Annotation: Subtype: Link Rect: 326, 436, 390, 444 Annotation: Subtype: Link Rect: 326, 384, 453, 392 Annotation: Subtype: Link Rect: 534, 342, 562, 350 Annotation: Subtype: Link Rect: 326, 332, 453, 340 Annotation: Subtype: Link Rect: 472, 269, 562, 277 Annotation: Subtype: Link Rect: 326, 258, 394, 266 Checksum: b1fe83c1 Type: CRC32 Checksum: 5a4b29ee49df6fb31ec9ce07469f2c34 Type: MD5 Checksum: 141787e98fb7c6bd9b78ba32246edf330b8d8081 Type: SHA-1