e64bae34b7a9cc218429ceb0d7fb1a3d 222856.pdf 1edcc203de5212e425930ca2c58f0333b26466a2 222856.pdf 846c0a1950c13a7ac4b81009bb1d0d5674cc1c15060695585cc8e45f02fe4cb8 222856.pdf Title: Benefit–risk profile of tofacitinib in patients with moderate‐to‐severe chronic plaque psoriasis: pooled analysis across six clinical trials Creator: Arbortext Advanced Print Publisher 9.1.531/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Sat May 4 16:48:53 2019 CEST ModDate: Sat May 4 16:48:53 2019 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 464778 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AGOFIG+AdvMETAN-C Type 1C WinAnsi yes yes no 86 0 AGOFMO+AdvP4C4E5E Type 1C Custom yes yes yes 92 0 AGOFMP+AdvPSJOANNA-B Type 1C WinAnsi yes yes no 127 0 AGOFNA+AdvPSJOANNA Type 1C Custom yes yes no 128 0 AGOFOA+AdvTTec369687+22 Type 1C Custom yes yes yes 132 0 AGOFOB+AdvTTec369687+20 Type 1C WinAnsi yes yes no 137 0 AGOFOC+AdvTT3713a231+20 Type 1C WinAnsi yes yes no 138 0 AGOFOD+AdvTTec369687 Type 1C WinAnsi yes yes no 142 0 AGOFIH+AdvNBSC85 Type 1C WinAnsi yes yes no 88 0 AGOFII+AdvMetaLF-M Type 1C WinAnsi yes yes no 89 0 AGOFIJ+AdvMETAB-R Type 1C MacRoman yes yes no 119 0 AGOFJK+AdvTT689d5d16.B+20 Type 1C WinAnsi yes yes no 87 0 AGOFJL+AdvMETAN-R Type 1C MacRoman yes yes no 120 0 AGOFKL+MyriadPro-Semibold Type 1C WinAnsi yes yes no 90 0 AGOFMM+AdvSPSASORT Type 1C Custom yes yes no 91 0 AGOFMN+AdvPSJOANNA-I Type 1C MacRoman yes yes no 125 0 AGOFPE+AdvMETAN-I Type 1C WinAnsi yes yes no 46 0 AGOGAE+AdvP4C4E74 Type 1C Custom yes yes no 51 0 AGOHBO+AdvPSJOANNA-SB Type 1C WinAnsi yes yes no 52 0 AGOHEO+AdvTir_symb Type 1C WinAnsi yes yes no 26 0 AGOHGO+AdvP4C4E59 Type 1C Custom yes yes no 33 0 AGOHHP+AdvPSMP13 Type 1C WinAnsi yes yes no 41 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-07 02:20:23 CET RepresentationInformation: 222856.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-11-11 16:23:32 CET Size: 464778 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, ISO PDF/A-1, Level B PDFMetadata: Objects: 151 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseThumbs Info: Title: Benefit–risk profile of tofacitinib in patients with moderate‐to‐severe chronic plaque psoriasis: pooled analysis across six clinical trials Creator: Arbortext Advanced Print Publisher 9.1.531/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Sat May 04 17:18:53 CEST 2019 ModDate: Sat May 04 17:18:53 CEST 2019 ID: 0xf4e668f782871bbf4d696272b8ba9d38, 0x7f4cec62de8bffa3c70ab4992fb26ae1 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1891 ImageHeight: 1936 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: AGOFNA+AdvPSJOANNA FontSubset: true FirstChar: 30 LastChar: 150 FontDescriptor: FontName: AGOFNA+AdvPSJOANNA Flags: Serif, Nonsymbolic FontBBox: -135, -239, 1000, 812 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: AGOHGO+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AGOHGO+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: AGOFOA+AdvTTec369687+22 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: AGOFOA+AdvTTec369687+22 Flags: Symbolic FontBBox: -156, -208, 802, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGOFOB+AdvTTec369687+20 FontSubset: true FirstChar: 134 LastChar: 150 FontDescriptor: FontName: AGOFOB+AdvTTec369687+20 Flags: Nonsymbolic FontBBox: -208, -208, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOHHP+AdvPSMP13 FontSubset: true FirstChar: 97 LastChar: 97 FontDescriptor: FontName: AGOHHP+AdvPSMP13 Flags: Nonsymbolic FontBBox: 0, -302, 958, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFOC+AdvTT3713a231+20 FontSubset: true FirstChar: 129 LastChar: 129 FontDescriptor: FontName: AGOFOC+AdvTT3713a231+20 Flags: Nonsymbolic FontBBox: -468, -208, 1708, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFOD+AdvTTec369687 FontSubset: true FirstChar: 42 LastChar: 169 FontDescriptor: FontName: AGOFOD+AdvTTec369687 Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFPE+AdvMETAN-I FontSubset: true FirstChar: 46 LastChar: 116 FontDescriptor: FontName: AGOFPE+AdvMETAN-I Flags: Serif, Nonsymbolic FontBBox: -177, -197, 1156, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOGAE+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: AGOGAE+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: AGOHBO+AdvPSJOANNA-SB FontSubset: true FirstChar: 46 LastChar: 108 FontDescriptor: FontName: AGOHBO+AdvPSJOANNA-SB Flags: Nonsymbolic FontBBox: -145, -239, 1000, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFIG+AdvMETAN-C FontSubset: true FirstChar: 65 LastChar: 84 FontDescriptor: FontName: AGOFIG+AdvMETAN-C Flags: Nonsymbolic FontBBox: -93, -187, 1166, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFIJ+AdvMETAB-R FontSubset: true FirstChar: 42 LastChar: 223 FontDescriptor: FontName: AGOFIJ+AdvMETAB-R Flags: Serif, Nonsymbolic FontBBox: -114, -218, 1197, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: AGOFJK+AdvTT689d5d16.B+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: AGOFJK+AdvTT689d5d16.B+20 Flags: Nonsymbolic FontBBox: -208, -208, 1177, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFIH+AdvNBSC85 FontSubset: true FirstChar: 66 LastChar: 74 FontDescriptor: FontName: AGOFIH+AdvNBSC85 Flags: Nonsymbolic FontBBox: -197, -281, 1197, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFJL+AdvMETAN-R FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: AGOFJL+AdvMETAN-R Flags: Nonsymbolic FontBBox: -93, -197, 1166, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: AGOFII+AdvMetaLF-M FontSubset: true FirstChar: 66 LastChar: 121 FontDescriptor: FontName: AGOFII+AdvMetaLF-M Flags: Serif, Nonsymbolic FontBBox: -156, -208, 1177, 916 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFKL+MyriadPro-Semibold FontSubset: true FirstChar: 68 LastChar: 105 FontDescriptor: FontName: AGOFKL+MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOHEO+AdvTir_symb FontSubset: true FirstChar: 57 LastChar: 57 FontDescriptor: FontName: AGOHEO+AdvTir_symb Flags: Nonsymbolic FontBBox: -166, -208, 1000, 729 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGOFMM+AdvSPSASORT FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AGOFMM+AdvSPSASORT Flags: Symbolic FontBBox: -281, -437, 1343, 989 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: AGOFMO+AdvP4C4E5E FontSubset: true FirstChar: 1 LastChar: 160 FontDescriptor: FontName: AGOFMO+AdvP4C4E5E Flags: Symbolic FontBBox: -52, -239, 1114, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGOFMN+AdvPSJOANNA-I FontSubset: true FirstChar: 40 LastChar: 223 FontDescriptor: FontName: AGOFMN+AdvPSJOANNA-I Flags: Serif, Nonsymbolic FontBBox: -156, -239, 1000, 812 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: AGOFMP+AdvPSJOANNA-B FontSubset: true FirstChar: 46 LastChar: 120 FontDescriptor: FontName: AGOFMP+AdvPSJOANNA-B Flags: Nonsymbolic FontBBox: -166, -239, 1000, 812 FontFile3: true Encoding: WinAnsiEncoding XMP: 2019-05-06T10:53:29+05:30 2019-05-06T10:53:29+05:30 2019-05-06T10:53:29+05:30 Acrobat Distiller 10.1.7 (Windows) 10.1111/bjd.17149 10.1111/(ISSN)1365-2133 3 VoR 10.1111/bjd.17149 application/pdf Benefit–risk profile of tofacitinib in patients with moderate‐to‐severe chronic plaque psoriasis: pooled analysis across six clinical trials uuid:89ff1c60-d786-4325-8841-8c6cd6498f7e uuid:4644bacb-176a-47ad-b592-f306732e240d Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 110, 643, 112, 653 Annotation: Subtype: Link Rect: 110, 643, 112, 653 Annotation: Subtype: Link Rect: 112, 643, 118, 654 Annotation: Subtype: Link Rect: 338, 643, 340, 653 Annotation: Subtype: Link Rect: 338, 643, 340, 653 Annotation: Subtype: Link Rect: 340, 643, 346, 654 Annotation: Subtype: Link Rect: 123, 463, 248, 471 Annotation: Subtype: Link Rect: 123, 463, 259, 471 Annotation: Subtype: Link Rect: 81, 366, 141, 374 Annotation: Subtype: Link Rect: 227, 21, 411, 29 Thumb: true Page: Label: 2 Thumb: true Page: Label: 3 Thumb: true Page: Label: 4 Thumb: true Page: Label: 5 Thumb: true Page: Label: 6 Thumb: true Page: Label: 7 Thumb: true Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 483, 125, 535, 133 Annotation: Subtype: Link Rect: 320, 115, 344, 123 Thumb: true Page: Label: 9 Thumb: true Checksum: f81134de Type: CRC32 Checksum: e64bae34b7a9cc218429ceb0d7fb1a3d Type: MD5 Checksum: 1edcc203de5212e425930ca2c58f0333b26466a2 Type: SHA-1