71ed1c6caee09dd75bb26a0c3ef9743f 222931.pdf 0be2c8d35d32942178fc4c3d8c02d59136e5ec81 222931.pdf b92090e71554deb2ccb47d1e57ac13e3f49ab8395d8fb6c2e5ff72249d83f368 222931.pdf Title: Statin use and the risk of colorectal cancer in a population-based electronic health records study Subject: Scientific Reports, doi:10.1038/s41598-019-49877-5 Keywords: Author: Gemma Ibamp#x000E1;amp#x000F1;ez-Sanz Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Thu Sep 12 05:19:07 2019 CEST ModDate: Fri Sep 13 13:52:20 2019 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 976225 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DRCPOC+Corbel-Bold CID TrueType Identity-H yes yes yes 34 0 FZNJLY+TimesNewRomanPSMT Type 1C WinAnsi yes yes yes 317 0 MinionPro-It Type 1C Custom yes no yes 132 0 EuclidSymbol-Bold Type 1C Custom yes no yes 318 0 DVMDIA+Corbel-Bold2 Type 1C WinAnsi yes yes yes 37 0 MinionPro-Regular Type 1C Custom yes no yes 36 0 ULGSWK+Corbel2 Type 1C WinAnsi yes yes yes 39 0 KJSPIO+Corbel CID TrueType Identity-H yes yes yes 40 0 MyriadPro-It Type 1C WinAnsi yes no yes 41 0 ULGSWK+Corbel2 Type 1C WinAnsi yes yes yes 200 0 MinionPro-Bold Type 1C Custom yes no yes 35 0 EuclidSymbol Type 1C Custom yes no yes 38 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-07 02:20:10 CET RepresentationInformation: 222931.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-11-18 09:20:23 CET Size: 976225 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd:Figure 1. Population flowchart and study design. SIDIAP includes subjects that have interacted with the Catalan public health system (~74% of the total Catalan population). The study selected all CRC patients in the period 2010–2015 aged 18 to :46' cannot be found Offset: 434297 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd: Table 1. Characteristics of the study according to statin use (controls only, N⁜琀㴠㄀㈀㤀㄀㄀㜀⻾￾￾￾＀⃾￾￾￾＀懾＀䄀搀樀甀猀琀攀搀 昀漀爀 愀最攀 愀渀搀 猀攀砀⻾￾＀⃾￾￾＀拾＀嘀愀爀椀愀戀氀攀猀 眀椀琀栀 洀椀猀猀椀渀最 搀愀琀愀⻾￾＀⃾￾＀一匀䄀䤀䐀㨀 一漀渀猀琀攀爀漀椀搀愀氀 愀渀琀椀ⴀ椀渀昀氀愀洀洀愀琀漀爀礀 搀爀甀最現￾＀㨀㔀㐩⽂潲摥牛〠〠そ⽓畢瑹灥⽌楮欯䉓㰼⽗‰⽔祰支䉯牤敲⽓⽓㸾⽒散瑛㈶㌮㠱㌠㈱㈮㘳㌠㈶㠮ㄹㄠ㈰〮㐹㉝⽈⽎⽁值㰯丠㜵‰⁒㸾㸾੥湤潢樊㘰‰扪਼㰯䘠㐯呹灥⽁湮潴⽄敳琨SpringerNature_SciRep_49877.indd: Table 1. Characteristics of the study according to statin use (controls only, N⁜琀㴠㄀㈀㤀㄀㄀㜀⻾￾￾￾＀⃾￾￾￾＀懾＀䄀搀樀甀猀琀攀搀 昀漀爀 愀最攀 愀渀搀 猀攀砀⻾￾＀⃾￾￾＀拾＀嘀愀爀椀愀戀氀攀猀 眀椀琀栀 洀椀猀猀椀渀最 搀愀琀愀⻾￾＀⃾￾＀一匀䄀䤀䐀㨀 一漀渀猀琀攀爀漀椀搀愀氀 愀渀琀椀ⴀ椀渀昀氀愀洀洀愀琀漀爀礀 搀爀甀最現￾＀㨀㔀㔩⽂潲摥牛〠〠そ⽓畢瑹灥⽌楮欯䉓㰼⽗‰⽔祰支䉯牤敲⽓⽓㸾⽒散瑛㈸㈮㘵ㄠㄵ㈮㘳㌠㈸㜮〴㠠ㄴ〮㐹㉝⽈⽎⽁值㰯丠㜶‰⁒㸾㸾੥湤潢樊㘱‰扪਼㰯䘠㐯呹灥⽁湮潴⽄敳琨SpringerNature_SciRep_49877.indd: Table 2. Statin use and CRC risk. aAdjusted for age, sex, socioeconomic status, region, year, body mass index, smoking, alcohol, comorbidities and nonsteroidal anti-inflammatory drugs use. bVariables with missi:56' cannot be found Offset: 434297 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd: Table 1. Characteristics of the study according to statin use (controls only, N⁜琀㴠㄀㈀㤀㄀㄀㜀⻾￾￾￾＀⃾￾￾￾＀懾＀䄀搀樀甀猀琀攀搀 昀漀爀 愀最攀 愀渀搀 猀攀砀⻾￾＀⃾￾￾＀拾＀嘀愀爀椀愀戀氀攀猀 眀椀琀栀 洀椀猀猀椀渀最 搀愀琀愀⻾￾＀⃾￾＀一匀䄀䤀䐀㨀 一漀渀猀琀攀爀漀椀搀愀氀 愀渀琀椀ⴀ椀渀昀氀愀洀洀愀琀漀爀礀 搀爀甀最現￾＀㨀㔀㔩⽂潲摥牛〠〠そ⽓畢瑹灥⽌楮欯䉓㰼⽗‰⽔祰支䉯牤敲⽓⽓㸾⽒散瑛㈸㈮㘵ㄠㄵ㈮㘳㌠㈸㜮〴㠠ㄴ〮㐹㉝⽈⽎⽁值㰯丠㜶‰⁒㸾㸾੥湤潢樊㘱‰扪਼㰯䘠㐯呹灥⽁湮潴⽄敳琨SpringerNature_SciRep_49877.indd: Table 2. Statin use and CRC risk. aAdjusted for age, sex, socioeconomic status, region, year, body mass index, smoking, alcohol, comorbidities and nonsteroidal anti-inflammatory drugs use. bVariables with missi:56' cannot be found Offset: 434297 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd: Table 2. Statin use and CRC risk. aAdjusted for age, sex, socioeconomic status, region, year, body mass index, smoking, alcohol, comorbidities and nonsteroidal anti-inflammatory drugs use. bVariables with missi:56' cannot be found Offset: 434297 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd: Table 2. Statin use and CRC risk. aAdjusted for age, sex, socioeconomic status, region, year, body mass index, smoking, alcohol, comorbidities and nonsteroidal anti-inflammatory drugs use. bVariables with miss:57' cannot be found Offset: 434297 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SpringerNature_SciRep_49877.indd: Table 2. Statin use and CRC risk. aAdjusted for age, sex, socioeconomic status, region, year, body mass index, smoking, alcohol, comorbidities and nonsteroidal anti-inflammatory drugs use. bVariables with mis:58' cannot be found Offset: 434297 MIMEtype: application/pdf PDFMetadata: Objects: 362 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseThumbs Language: EN Outlines: Item: Title: Statin use and the risk of colorectal cancer in a population-based electronic health records study Children: Item: Title: Methods Children: Item: Title: Data source. Item: Title: Study design. Item: Title: Exposure variables. Item: Title: Confounders. Item: Title: Statistical analysis. Item: Title: Results Children: Item: Title: Baseline characteristics and statin exposure. Item: Title: Statin use and colorectal cancer. Item: Title: Statin use and rectal cancer. Item: Title: Analysis of other lipid lowering drugs. Item: Title: Discussion Item: Title: Acknowledgements Item: Title: Figure 1 Population flowchart and study design. Item: Title: Table 1 Characteristics of the study according to statin use (controls only, N = 129117). Item: Title: Table 2 Statin use and CRC risk. Item: Title: Table 3 Analyses of statins effect according to CRC location. Info: Title: Statin use and the risk of colorectal cancer in a population-based electronic health records study Author: Gemma Ibamp#x000E1;amp#x000F1;ez-Sanz Subject: Scientific Reports, doi:10.1038/s41598-019-49877-5 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Thu Sep 12 05:49:07 CEST 2019 ModDate: Fri Sep 13 13:52:20 CEST 2019 ID: 0xfa35962037044789298b86862fa80b46, 0x3b36d19227921e7227d3ef34159e4517 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: DRCPOC+Corbel-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: KJSPIO+Corbel Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: DVMDIA+Corbel-Bold2 FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: DVMDIA+Corbel-Bold2 Flags: Nonsymbolic FontBBox: -556, -239, 1155, 952 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: EuclidSymbol FirstChar: 0 LastChar: 255 FontDescriptor: FontName: EuclidSymbol Flags: Symbolic FontBBox: -166, -253, 1090, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ULGSWK+Corbel2 FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: ULGSWK+Corbel2 Flags: Nonsymbolic FontBBox: -553, -239, 1110, 952 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: FZNJLY+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 120 FontDescriptor: FontName: FZNJLY+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: EuclidSymbol-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: EuclidSymbol-Bold Flags: Symbolic FontBBox: -186, -308, 1101, 960 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: DRCPOC+Corbel-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: DRCPOC+Corbel-Bold Flags: Symbolic FontBBox: -556, -239, 1155, 952 FontFile2: true Font: BaseFont: KJSPIO+Corbel CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: KJSPIO+Corbel Flags: Symbolic FontBBox: -553, -239, 1110, 952 FontFile2: true XMP: application/pdf doi:10.1038/s41598-019-49877-5 Springer US Scientific Reports, doi:10.1038/s41598-019-49877-5 Statin use and the risk of colorectal cancer in a population-based electronic health records study Gemma Ibamp#x000E1;amp#x000F1;ez-Sanz Elisabet Guinamp#x000F3; Caridad Pontes Mamp#x000AA; amp#x000C1;ngeles Quijada-Manuitt Luisa C Peamp#x000F1;a-Negro Maramp#x000ED;a Aragamp#x000F3;n Marga Domamp#x000ED;nguez Lorena Rodramp#x000ED;guez-Alonso Alex Blasco Ana Garcamp#x000ED;a-Rodramp#x000ED;guez Rosa Morros Victor Moreno 10.1038/s41598-019-49877-5 http://dx.doi.org/10.1038/s41598-019-49877-5 journal Scientific Reports © 2019, The Author(s) 2045-2322 10.1038/s41598-019-49877-5 Springer 2019-09-13T13:52:20+02:00 2019-09-12T08:49:07+05:30 2019-09-13T13:52:20+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) VoR uuid:936c1c31-8faa-4602-a52a-fd86d44b7a55 uuid:320dffef-846b-4f0d-afad-fb10c5e4d297 default 1 converted uuid:512a6377-64ed-48bd-b247-b7afa7791797 converted to PDF/A-2b pdfToolbox 2019-09-12T08:49:51+05:30 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Copyright copyright Text external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. issn Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url Text http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 244, 538, 253, 526 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 217, 502, 226, 490 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 409, 318, 412, 306 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 277, 308, 279, 296 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 527, 298, 529, 286 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 442, 288, 445, 276 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 448, 288, 451, 276 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 537, 288, 540, 276 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 541, 288, 544, 276 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 353, 268, 356, 256 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 358, 268, 363, 256 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 480, 268, 486, 256 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 218, 218, 223, 206 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 225, 218, 230, 206 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 323, 218, 329, 206 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 332, 218, 337, 206 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 296, 198, 301, 186 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 383, 188, 389, 176 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 390, 188, 396, 176 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 315, 53, 396, 43 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 451, 53, 547, 43 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 524, 432, 530, 420 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 533, 432, 538, 420 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 540, 432, 545, 420 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 227, 374, 282, 362 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 285, 374, 291, 362 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 531, 324, 537, 312 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 513, 294, 518, 282 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 532, 196, 536, 183 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 546, 704, 552, 692 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 301, 684, 362, 672 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 249, 664, 334, 652 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 444, 566, 450, 554 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 217, 476, 223, 464 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 538, 448, 540, 436 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 542, 448, 545, 436 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 546, 448, 552, 436 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 477, 438, 483, 426 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 303, 122, 307, 110 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 303, 122, 307, 110 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 303, 122, 307, 110 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 279, 92, 283, 80 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 283, 287, 271 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 290, 161, 295, 149 Flags: Print AppearanceDictionary: true Destination: 133 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 183, 256, 189, 244 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 190, 256, 196, 244 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 181, 246, 187, 234 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 198, 236, 203, 224 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 205, 236, 210, 224 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 212, 236, 217, 224 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 538, 226, 543, 214 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 546, 226, 552, 214 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 199, 176, 204, 164 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 209, 136, 215, 124 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 297, 136, 303, 124 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 304, 136, 310, 124 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 441, 136, 446, 124 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 278, 116, 283, 104 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 285, 116, 290, 104 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 395, 76, 401, 64 Flags: Print AppearanceDictionary: true Destination: 156 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 208, 435, 214, 423 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 228, 425, 234, 413 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 208, 375, 214, 363 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 215, 375, 221, 363 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 222, 375, 228, 363 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 543, 365, 549, 353 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 457, 345, 463, 333 Flags: Print AppearanceDictionary: true Destination: 156 Annotation: Subtype: Link Rect: 308, 63, 362, 51 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 535, 724, 554, 714 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 716, 214, 706 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 393, 453, 383 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 376, 367, 424, 357 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 223, 25, 370, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 356, 599, 515, 586 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 344, 455, 504, 443 Flags: Print AppearanceDictionary: true Thumb: true Checksum: 1d7df370 Type: CRC32 Checksum: 71ed1c6caee09dd75bb26a0c3ef9743f Type: MD5 Checksum: 0be2c8d35d32942178fc4c3d8c02d59136e5ec81 Type: SHA-1