b4693dc21388f9e681c7a85c6b390bf3  223420.pdf
100754f022c951dd026ba8f1423a0f01e0180f4a  223420.pdf
26b5119b3eecb9c162f8a3f94dc1f2d413044985dc6e7cbbb97ab75107a4fc8e  223420.pdf

Title:          Recent Advances in the Targeting of Epigenetic Regulators in B-Cell Non-Hodgkin Lymphoma
Subject:        In the last 10 years, major advances have been made in the diagnosis and development of selective therapies for several blood cancers, including B-cell non-Hodgkin lymphoma (B-NHL), a heterogeneous group of malignancies arising from the mature B lymphocy
Keywords:       B-cell lymphoma, DNMT, EZH2, HDAC, PRMT inhibitor, BET bromodomain inhibitor (BETi), combination therapy
Author:         Marcelo L. Ribeiro
Creator:        Adobe InDesign CC 2015 (Windows)
Producer:       Adobe PDF Library 15.0
CreationDate:   Tue Oct 15 22:25:23 2019 CEST
ModDate:        Wed Oct 16 03:40:48 2019 CEST
Tagged:         yes
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          24
Encrypted:      no
Page size:      595.276 x 779.528 pts
Page rot:       0
File size:      2089317 bytes
Optimized:      no
PDF version:    1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
HelveticaNeueLTStd-Bd                Type 1C           Custom           yes no  yes   3681  0
HelveticaNeueLTStd-BdIt              Type 1C           WinAnsi          yes no  yes   3682  0
HelveticaNeueLTStd-LtIt              Type 1C           Custom           yes no  yes   3683  0
HelveticaNeueLTStd-MdIt              Type 1C           WinAnsi          yes no  yes   3692  0
HelveticaNeueLTStd-Lt                Type 1C           Custom           yes no  yes   3693  0
MinionPro-Regular                    Type 1C           Custom           yes no  yes   3698  0
MinionPro-Bold                       Type 1C           Custom           yes no  yes   3703  0
MinionPro-It                         Type 1C           Custom           yes no  yes    303  0
BCXQKW+STIXGeneral                   Type 1C           Custom           yes yes yes    358  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2021-03-03 02:22:11 CET
 RepresentationInformation: 223420.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2021-03-01 17:06:13 CET
  Size: 2089317
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 3760
   FreeObjects: 3617
   IncrementalUpdates: 3
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Recent Advances in the Targeting of Epigenetic Regulators in B-Cell Non-Hodgkin Lymphoma
      Children: 
       Item: 
        Title: Introduction
        Children: 
         Item: 
          Title: Characteristics of B-Cell Non-Hodgkin Lymphoma (B-NHL)
         Item: 
          Title: Altered Chromatin-Modifying Enzymes 
in B-NHL
       Item: 
        Title: Targeting Writer Epigenetic Enzymes
        Children: 
         Item: 
          Title: DNMT Inhibitors
         Item: 
          Title: EZH2 Inhibitors
         Item: 
          Title: PRMT Inhibitors
       Item: 
        Title: Targeting Eraser Epigenetic Enzymes: HDAC Inhibitors
       Item: 
        Title: Targeting Reader Epigenetic Enzymes
        Children: 
         Item: 
          Title: BET Inhibitors
         Item: 
          Title: Non-BET Bromodomain-Containing Proteins: the Histone Acetyltransferase CREB-Binding Protein (CBP)
       Item: 
        Title: Chromatin Remodelers: SWI/SNF and BRG1 and ARID1
       Item: 
        Title: Indirect Inhibition of Epigenetic Dysregulation by IDH Inhibitors
       Item: 
        Title: Combination Involving Epigenetic-Targeting Approaches
        Children: 
         Item: 
          Title: Concomitant Targeting of Different Epigenetic Modulators
         Item: 
          Title: Combination of Epigenetic Drugs With Other Classes of Anti-Tumoral Drugs
       Item: 
        Title: Conclusions
       Item: 
        Title: Author Contributions
       Item: 
        Title: Funding
       Item: 
        Title: References
   Info: 
    Title: Recent Advances in the Targeting of Epigenetic Regulators in B-Cell Non-Hodgkin Lymphoma
    Author: Marcelo L. Ribeiro
    Subject: In the last 10 years, major advances have been made in the diagnosis and development of selective therapies for several blood cancers, including B-cell non-Hodgkin lymphoma (B-NHL), a heterogeneous group of malignancies arising from the mature B lymphocy
    Keywords: B-cell lymphoma, DNMT, EZH2, HDAC, PRMT inhibitor, BET bromodomain inhibitor (BETi), combination therapy
    Creator: Adobe InDesign CC 2015 (Windows)
    Producer: Adobe PDF Library 15.0
    CreationDate: Tue Oct 15 22:25:23 CEST 2019
    ModDate: Wed Oct 16 03:40:48 CEST 2019
   ID: 0x5c0265e015e10f468c6b3ffed9e4989d, 0x596141e506abed4abf49728f78933714
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 980
      ImageHeight: 614
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 980
      ImageHeight: 621
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 996
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1782
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 2280
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: HelveticaNeueLTStd-Bd
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HelveticaNeueLTStd-Bd
       Flags: Nonsymbolic
       FontBBox: -166, -218, 1078, 975
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -290, -360, 1684, 989
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HelveticaNeueLTStd-BdIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HelveticaNeueLTStd-BdIt
       Flags: Nonsymbolic, Italic
       FontBBox: -166, -218, 1129, 975
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: HelveticaNeueLTStd-LtIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HelveticaNeueLTStd-LtIt
       Flags: Nonsymbolic, Italic
       FontBBox: -165, -214, 1099, 951
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BCXQKW+STIXGeneral
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: BCXQKW+STIXGeneral
       Flags: Serif, Nonsymbolic
       FontBBox: -178, -443, 2000, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-Bold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -319, -360, 1684, 1024
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: HelveticaNeueLTStd-MdIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HelveticaNeueLTStd-MdIt
       Flags: Nonsymbolic, Italic
       FontBBox: -165, -218, 1125, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: HelveticaNeueLTStd-Lt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: HelveticaNeueLTStd-Lt
       Flags: Nonsymbolic
       FontBBox: -166, -214, 1050, 967
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-It
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -201, -360, 1684, 1002
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="3.1-701">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Recent Advances in the Targeting of Epigenetic Regulators in B-Cell Non-Hodgkin Lymphoma</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">In the last 10 years, major advances have been made in the diagnosis and development of selective therapies for several blood cancers, including B-cell non-Hodgkin lymphoma (B-NHL), a heterogeneous group of malignancies arising from the mature B lymphocy</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:creator>
            <rdf:Bag>
               <rdf:li>Marcelo L. Ribeiro</rdf:li>
               <rdf:li>Diana Reyes-Garau</rdf:li>
               <rdf:li>Marc Armengol</rdf:li>
               <rdf:li>Miranda Fernández-Serrano</rdf:li>
               <rdf:li>Gaël Roué</rdf:li>
            </rdf:Bag>
         </dc:creator>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>B-cell lymphoma</rdf:li>
               <rdf:li>DNMT</rdf:li>
               <rdf:li>EZH2</rdf:li>
               <rdf:li>HDAC</rdf:li>
               <rdf:li>PRMT inhibitor</rdf:li>
               <rdf:li>BET bromodomain inhibitor (BETi)</rdf:li>
               <rdf:li>combination therapy</rdf:li>
            </rdf:Bag>
         </dc:subject>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xap="http://ns.adobe.com/xap/1.0/">
         <xap:CreateDate>2019-10-16T04:25:23+08:00</xap:CreateDate>
         <xap:MetadataDate>2019-10-16T09:40:48+08:00</xap:MetadataDate>
         <xap:ModifyDate>2019-10-16T09:40:48+08:00</xap:ModifyDate>
         <xap:CreatorTool>Adobe InDesign CC 2015 (Windows)</xap:CreatorTool>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
         <xapMM:InstanceID>uuid:8dbfef99-773c-4eef-83d6-864e5fe1f951</xapMM:InstanceID>
         <xapMM:OriginalDocumentID>xmp.did:2aecd8bd-cbd3-4539-b083-9de383973cbe</xapMM:OriginalDocumentID>
         <xapMM:DocumentID>xmp.id:e911fb14-9180-c94d-9b8c-e710694c4644</xapMM:DocumentID>
         <xapMM:RenditionClass>proof:pdf</xapMM:RenditionClass>
         <xapMM:DerivedFrom rdf:parseType="Resource">
            <stRef:instanceID>xmp.iid:6810b77b-a562-f346-92e9-5907c988eb9d</stRef:instanceID>
            <stRef:documentID>xmp.did:48c0fc82-a37f-5f4b-bdfc-6e238fb522f5</stRef:documentID>
            <stRef:originalDocumentID>xmp.did:2aecd8bd-cbd3-4539-b083-9de383973cbe</stRef:originalDocumentID>
            <stRef:renditionClass>default</stRef:renditionClass>
         </xapMM:DerivedFrom>
         <xapMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:parameters>from application/x-indesign to application/pdf</stEvt:parameters>
                  <stEvt:softwareAgent>Adobe InDesign CC 2015 (Windows)</stEvt:softwareAgent>
                  <stEvt:changed>/</stEvt:changed>
                  <stEvt:when>2019-10-16T04:25:23+08:00</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xapMM:History>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Adobe PDF Library 15.0</pdf:Producer>
         <pdf:Trapped>False</pdf:Trapped>
         <pdf:Keywords>B-cell lymphoma, DNMT, EZH2, HDAC, PRMT inhibitor, BET bromodomain inhibitor (BETi), combination therapy</pdf:Keywords>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 84, 443, 160, 432
      Annotation: 
       Subtype: Link
       Rect: 103, 284, 158, 276
      Annotation: 
       Subtype: Link
       Rect: 99, 264, 158, 256
      Annotation: 
       Subtype: Link
       Rect: 75, 73, 158, 65
      Annotation: 
       Subtype: Link
       Rect: 175, 643, 543, 618
      Annotation: 
       Subtype: Link
       Rect: 175, 620, 543, 595
      Annotation: 
       Subtype: Link
       Rect: 175, 597, 376, 572
      Annotation: 
       Subtype: Link
       Rect: 175, 560, 250, 549
      Annotation: 
       Subtype: Link
       Rect: 267, 560, 346, 549
      Annotation: 
       Subtype: Link
       Rect: 355, 560, 418, 549
      Annotation: 
       Subtype: Link
       Rect: 427, 560, 542, 549
      Annotation: 
       Subtype: Link
       Rect: 193, 549, 236, 538
      Annotation: 
       Subtype: Link
       Rect: 516, 76, 546, 63
       ActionDest: 1
      Annotation: 
       Subtype: Link
       Rect: 43, 755, 135, 719
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
      Annotation: 
       Subtype: Link
       Rect: 453, 745, 551, 736
      Annotation: 
       Subtype: Link
       Rect: 466, 728, 549, 720
      Annotation: 
       Subtype: Link
       Rect: 453, 737, 551, 728
      Annotation: 
       Subtype: Link
       Rect: 519, 708, 551, 676
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 48, 177, 129, 165
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 136, 177, 244, 165
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 251, 177, 288, 165
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 45, 166, 92, 153
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 483, 685, 534, 676
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 483, 647, 547, 638
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 483, 637, 541, 629
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 483, 609, 539, 600
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 483, 571, 539, 562
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 483, 542, 544, 534
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 483, 533, 539, 524
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 483, 504, 539, 496
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 483, 495, 534, 486
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 483, 466, 536, 458
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 483, 457, 544, 448
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 483, 447, 546, 439
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 483, 438, 542, 429
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 483, 400, 531, 391
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 483, 390, 531, 382
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 483, 352, 540, 344
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 483, 343, 534, 334
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 481, 333, 497, 325
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 500, 333, 547, 325
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 481, 324, 497, 315
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 483, 314, 534, 306
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 481, 305, 497, 296
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 500, 305, 542, 296
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 481, 295, 497, 287
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 483, 276, 539, 268
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 483, 267, 543, 258
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 214, 420, 285, 408
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 48, 409, 80, 396
       ActionDest: 1
      Annotation: 
       Subtype: Link
       Rect: 186, 398, 220, 385
       ActionDest: 6
      Annotation: 
       Subtype: Link
       Rect: 473, 533, 547, 520
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 306, 521, 405, 509
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 431, 475, 503, 463
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 408, 418, 493, 405
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 443, 314, 516, 302
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 521, 314, 549, 302
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 306, 303, 349, 290
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 446, 268, 513, 256
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 432, 234, 500, 221
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 505, 234, 549, 221
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 306, 222, 354, 210
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 361, 222, 427, 210
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 340, 188, 402, 175
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 407, 188, 476, 175
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 481, 188, 549, 175
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 306, 176, 329, 164
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 333, 176, 394, 164
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 462, 96, 544, 83
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 68, 639, 97, 626
       ActionDest: 13
      Annotation: 
       Subtype: Link
       Rect: 131, 535, 189, 523
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 101, 501, 133, 488
       ActionDest: 22
      Annotation: 
       Subtype: Link
       Rect: 120, 466, 196, 454
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 201, 466, 283, 454
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 88, 397, 174, 385
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 179, 397, 233, 385
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 202, 340, 288, 327
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 328, 63, 316
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 48, 294, 128, 281
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 309, 696, 397, 684
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 418, 673, 488, 661
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 348, 662, 422, 649
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 456, 639, 510, 626
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 349, 570, 416, 557
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 370, 535, 437, 523
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 467, 501, 519, 488
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 524, 501, 549, 488
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 489, 345, 477
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 374, 455, 403, 442
       ActionDest: 13
      Annotation: 
       Subtype: Link
       Rect: 422, 455, 455, 442
       ActionDest: 22
      Annotation: 
       Subtype: Link
       Rect: 465, 455, 547, 442
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 305, 443, 380, 431
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 386, 443, 464, 431
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 367, 409, 437, 396
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 441, 409, 503, 396
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 465, 375, 494, 362
       ActionDest: 35
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 48, 173, 130, 161
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 137, 173, 230, 161
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 48, 116, 125, 103
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 129, 116, 204, 103
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 208, 116, 286, 103
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 45, 104, 138, 92
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 353, 380, 404, 367
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 408, 380, 475, 367
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 525, 368, 549, 355
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 356, 324, 344
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 329, 356, 415, 344
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 421, 356, 489, 344
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 481, 333, 547, 321
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 322, 366, 309
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 520, 276, 549, 263
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 305, 264, 347, 252
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 309, 230, 389, 217
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 395, 230, 462, 217
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 468, 230, 544, 217
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 494, 195, 549, 183
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 184, 324, 171
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 328, 184, 404, 171
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 512, 172, 549, 160
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 305, 161, 352, 148
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 357, 161, 431, 148
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 309, 138, 381, 125
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 339, 115, 414, 102
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 371, 92, 452, 79
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 141, 202, 281, 193
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 125, 421, 192, 409
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 48, 387, 125, 374
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 172, 375, 259, 363
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 159, 329, 250, 317
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 210, 261, 286, 248
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 249, 132, 236
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 249, 237, 288, 225
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 45, 226, 63, 213
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 138, 191, 204, 179
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 91, 88, 154, 75
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 332, 411, 427, 398
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 432, 411, 501, 398
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 511, 411, 544, 398
       ActionDest: 22
      Annotation: 
       Subtype: Link
       Rect: 454, 273, 547, 260
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 261, 390, 248
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 431, 215, 506, 202
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 309, 158, 379, 145
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 384, 158, 465, 145
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 194, 451, 265, 443
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 48, 708, 135, 695
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 124, 673, 204, 661
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 48, 650, 152, 638
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 158, 650, 255, 638
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 258, 627, 288, 615
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 45, 616, 112, 603
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 156, 386, 212, 373
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 141, 317, 207, 304
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 212, 317, 283, 304
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 80, 271, 162, 258
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 168, 271, 247, 258
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 143, 248, 206, 235
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 211, 248, 268, 235
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 81, 179, 152, 166
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 48, 87, 138, 74
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 516, 708, 549, 695
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 696, 346, 684
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 350, 696, 417, 684
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 430, 685, 501, 672
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 496, 616, 549, 603
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 604, 371, 592
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 361, 489, 446, 477
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 465, 432, 549, 419
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 420, 324, 408
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 309, 409, 386, 396
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 493, 363, 549, 350
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 305, 351, 353, 339
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 309, 259, 400, 247
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 309, 225, 397, 212
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 403, 225, 473, 212
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 502, 133, 549, 120
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 122, 324, 109
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 420, 87, 506, 74
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 48, 719, 126, 707
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 253, 696, 288, 684
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 45, 685, 64, 672
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 48, 570, 137, 557
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 264, 478, 288, 465
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 466, 121, 454
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 206, 351, 283, 339
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 129, 248, 231, 235
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 167, 167, 244, 155
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 426, 719, 498, 707
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 502, 719, 549, 707
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 305, 708, 346, 695
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 412, 685, 508, 672
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 345, 662, 429, 649
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 434, 662, 508, 649
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 519, 604, 549, 592
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 305, 593, 346, 580
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 351, 593, 424, 580
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 408, 581, 481, 569
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 462, 558, 549, 546
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 547, 324, 534
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 472, 524, 547, 511
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 512, 373, 500
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 378, 512, 449, 500
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 454, 512, 531, 500
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 535, 455, 549, 442
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 305, 443, 347, 431
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 309, 420, 366, 408
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 440, 363, 511, 350
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 516, 363, 549, 350
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 351, 346, 339
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 351, 351, 421, 339
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 426, 351, 501, 339
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 506, 351, 549, 339
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 340, 324, 327
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 329, 340, 400, 327
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 406, 340, 512, 327
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 460, 294, 534, 281
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 345, 236, 417, 224
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 470, 213, 532, 201
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 444, 190, 513, 178
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 519, 190, 549, 178
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 179, 377, 166
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 405, 121, 491, 109
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 498, 121, 549, 109
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 305, 110, 324, 97
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 329, 110, 403, 97
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 409, 110, 470, 97
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 476, 110, 547, 97
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 305, 99, 376, 86
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 383, 99, 488, 86
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 499, 99, 530, 86
       ActionDest: 13
      Annotation: 
       Subtype: Link
       Rect: 305, 87, 339, 74
       ActionDest: 22
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 242, 616, 288, 603
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 45, 604, 85, 592
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 89, 604, 156, 592
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 48, 570, 118, 557
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 168, 443, 239, 431
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 163, 420, 235, 408
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 128, 386, 204, 373
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 95, 340, 181, 327
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 48, 271, 116, 258
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 123, 271, 227, 258
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 234, 271, 288, 258
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 45, 259, 63, 247
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 69, 259, 140, 247
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 146, 259, 217, 247
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 119, 225, 209, 212
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 149, 144, 210, 132
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 261, 75, 288, 63
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 305, 719, 346, 707
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 343, 685, 407, 672
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 375, 489, 485, 477
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 492, 489, 549, 477
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 478, 324, 465
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 328, 478, 412, 465
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 354, 397, 458, 385
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 469, 317, 547, 304
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 305, 305, 381, 293
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 385, 305, 484, 293
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 352, 271, 422, 258
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 473, 202, 520, 189
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 453, 156, 512, 143
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 419, 110, 503, 97
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 530, 75, 549, 63
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 45, 719, 86, 707
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 205, 696, 288, 684
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 45, 685, 63, 672
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 81, 627, 189, 615
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 194, 627, 263, 615
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 257, 604, 288, 592
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 593, 87, 580
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 209, 593, 285, 580
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 48, 535, 152, 523
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 156, 535, 232, 523
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 204, 490, 288, 477
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 45, 478, 63, 465
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 188, 443, 252, 431
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 201, 397, 286, 385
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 45, 386, 110, 373
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 74, 351, 176, 339
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 255, 351, 288, 339
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 340, 87, 327
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 48, 317, 155, 304
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 122, 190, 170, 178
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 469, 685, 531, 672
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 380, 593, 409, 580
       ActionDest: 71
      Annotation: 
       Subtype: Link
       Rect: 411, 501, 444, 488
       ActionDest: 35
      Annotation: 
       Subtype: Link
       Rect: 309, 466, 397, 454
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 468, 432, 533, 419
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 432, 374, 532, 362
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 331, 84, 402, 76
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 113, 175, 188, 162
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 513, 210, 549, 197
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 305, 198, 347, 185
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 385, 187, 464, 174
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 470, 187, 544, 174
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 422, 152, 491, 139
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 497, 152, 549, 139
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 141, 324, 128
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 329, 141, 391, 128
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 309, 95, 365, 82
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 183, 608, 288, 595
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 45, 596, 63, 584
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 135, 562, 203, 549
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 99, 527, 170, 515
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 174, 527, 260, 515
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 166, 504, 251, 492
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 84, 458, 152, 446
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 157, 458, 225, 446
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 244, 435, 288, 423
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 424, 63, 411
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 78, 412, 142, 400
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 146, 412, 240, 400
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 245, 412, 288, 400
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 401, 63, 388
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 204, 355, 286, 342
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 343, 127, 331
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 131, 343, 222, 331
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 164, 237, 264, 224
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 112, 191, 225, 178
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 247, 168, 288, 155
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 156, 62, 144
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 158, 76, 229, 63
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 474, 696, 544, 684
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 507, 662, 549, 649
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 305, 650, 360, 638
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 487, 593, 547, 580
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 581, 367, 569
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 370, 581, 432, 569
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 426, 570, 500, 557
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 446, 524, 519, 511
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 345, 478, 397, 465
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 401, 478, 474, 465
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 432, 374, 494, 362
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 353, 340, 435, 327
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 503, 340, 549, 327
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 305, 328, 324, 316
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 398, 328, 464, 316
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 535, 328, 549, 316
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 305, 317, 346, 304
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 416, 317, 486, 304
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 426, 305, 507, 293
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 514, 305, 549, 293
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 305, 294, 349, 281
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 479, 248, 546, 235
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 382, 237, 442, 224
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 368, 179, 444, 166
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 48, 682, 109, 669
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 112, 682, 180, 669
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 268, 555, 288, 543
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 544, 93, 531
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 238, 498, 288, 485
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 486, 63, 474
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 140, 463, 224, 451
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 231, 463, 288, 451
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 45, 452, 63, 439
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 124, 452, 188, 439
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 67, 440, 121, 428
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 119, 394, 192, 382
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 209, 371, 285, 359
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 246, 360, 288, 347
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 45, 348, 90, 336
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 96, 348, 164, 336
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 242, 348, 288, 336
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 45, 337, 63, 324
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 68, 337, 138, 324
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 143, 337, 214, 324
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 273, 302, 288, 290
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 45, 291, 120, 278
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 197, 233, 257, 221
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 268, 176, 288, 163
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 164, 92, 152
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 99, 164, 251, 152
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 133, 95, 220, 83
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 453, 544, 530, 531
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 535, 544, 549, 531
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 305, 532, 484, 520
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 475, 486, 544, 474
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 510, 452, 544, 439
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 426, 417, 469, 405
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 475, 417, 546, 405
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 309, 394, 400, 382
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 405, 394, 474, 382
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 395, 348, 478, 336
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 477, 337, 544, 324
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 394, 302, 459, 290
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 377, 279, 459, 267
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 376, 199, 445, 186
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 309, 84, 368, 71
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 15
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 116, 696, 207, 684
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 48, 501, 123, 488
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 128, 501, 190, 488
       ActionDest: 201
      Annotation: 
       Subtype: Link
       Rect: 48, 421, 81, 408
       ActionDest: 91
      Annotation: 
       Subtype: Link
       Rect: 156, 351, 236, 339
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 242, 351, 288, 339
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 45, 340, 92, 327
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 97, 340, 172, 327
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 176, 340, 233, 327
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 48, 294, 116, 281
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 217, 213, 283, 201
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 241, 75, 288, 63
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 305, 719, 324, 707
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 463, 696, 544, 684
       ActionDest: 129
      Annotation: 
       Subtype: Link
       Rect: 463, 650, 544, 638
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 309, 604, 377, 592
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 403, 558, 483, 546
       ActionDest: 183
      Annotation: 
       Subtype: Link
       Rect: 392, 524, 469, 511
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 417, 466, 503, 454
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 376, 432, 451, 419
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 340, 374, 404, 362
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 309, 328, 376, 316
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 309, 259, 372, 247
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 341, 202, 408, 189
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 413, 202, 473, 189
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 506, 167, 549, 155
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 305, 156, 323, 143
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 309, 133, 370, 120
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 425, 133, 480, 120
       ActionDest: 156
      Annotation: 
       Subtype: Link
       Rect: 325, 99, 380, 86
       ActionDest: 192
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 16
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 229, 697, 288, 684
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 45, 685, 62, 672
       ActionDest: 147
      Annotation: 
       Subtype: Link
       Rect: 76, 650, 141, 638
       ActionDest: 174
      Annotation: 
       Subtype: Link
       Rect: 157, 627, 216, 615
       ActionDest: 138
      Annotation: 
       Subtype: Link
       Rect: 220, 627, 276, 615
       ActionDest: 165
      Annotation: 
       Subtype: Link
       Rect: 156, 206, 250, 196
      Annotation: 
       Subtype: Link
       Rect: 128, 168, 211, 158
      Annotation: 
       Subtype: Link
       Rect: 124, 130, 207, 120
      Annotation: 
       Subtype: Link
       Rect: 175, 73, 277, 63
      Annotation: 
       Subtype: Link
       Rect: 445, 226, 533, 215
      Annotation: 
       Subtype: Link
       Rect: 365, 187, 466, 177
      Annotation: 
       Subtype: Link
       Rect: 328, 149, 423, 139
      Annotation: 
       Subtype: Link
       Rect: 523, 121, 549, 111
      Annotation: 
       Subtype: Link
       Rect: 315, 111, 384, 101
      Annotation: 
       Subtype: Link
       Rect: 444, 74, 541, 63
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 17
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 114, 700, 178, 690
      Annotation: 
       Subtype: Link
       Rect: 195, 672, 285, 661
      Annotation: 
       Subtype: Link
       Rect: 174, 643, 237, 633
      Annotation: 
       Subtype: Link
       Rect: 107, 605, 170, 595
      Annotation: 
       Subtype: Link
       Rect: 128, 577, 208, 566
      Annotation: 
       Subtype: Link
       Rect: 107, 538, 161, 528
      Annotation: 
       Subtype: Link
       Rect: 263, 482, 288, 471
      Annotation: 
       Subtype: Link
       Rect: 55, 472, 84, 462
      Annotation: 
       Subtype: Link
       Rect: 263, 444, 288, 433
      Annotation: 
       Subtype: Link
       Rect: 55, 434, 122, 424
      Annotation: 
       Subtype: Link
       Rect: 263, 368, 288, 357
      Annotation: 
       Subtype: Link
       Rect: 55, 358, 106, 348
      Annotation: 
       Subtype: Link
       Rect: 189, 339, 276, 329
      Annotation: 
       Subtype: Link
       Rect: 55, 301, 130, 291
      Annotation: 
       Subtype: Link
       Rect: 55, 272, 122, 262
      Annotation: 
       Subtype: Link
       Rect: 55, 206, 132, 196
      Annotation: 
       Subtype: Link
       Rect: 258, 187, 288, 177
      Annotation: 
       Subtype: Link
       Rect: 55, 177, 112, 167
      Annotation: 
       Subtype: Link
       Rect: 263, 149, 288, 139
      Annotation: 
       Subtype: Link
       Rect: 55, 139, 123, 129
      Annotation: 
       Subtype: Link
       Rect: 178, 92, 261, 82
      Annotation: 
       Subtype: Link
       Rect: 471, 700, 534, 690
      Annotation: 
       Subtype: Link
       Rect: 315, 671, 410, 661
      Annotation: 
       Subtype: Link
       Rect: 358, 633, 433, 623
      Annotation: 
       Subtype: Link
       Rect: 353, 586, 455, 576
      Annotation: 
       Subtype: Link
       Rect: 315, 548, 410, 538
      Annotation: 
       Subtype: Link
       Rect: 363, 510, 465, 500
      Annotation: 
       Subtype: Link
       Rect: 495, 491, 543, 481
      Annotation: 
       Subtype: Link
       Rect: 364, 462, 432, 452
      Annotation: 
       Subtype: Link
       Rect: 449, 434, 526, 424
      Annotation: 
       Subtype: Link
       Rect: 365, 396, 459, 386
      Annotation: 
       Subtype: Link
       Rect: 523, 368, 549, 357
      Annotation: 
       Subtype: Link
       Rect: 315, 358, 384, 348
      Annotation: 
       Subtype: Link
       Rect: 397, 330, 492, 319
      Annotation: 
       Subtype: Link
       Rect: 523, 301, 549, 291
      Annotation: 
       Subtype: Link
       Rect: 315, 291, 384, 281
      Annotation: 
       Subtype: Link
       Rect: 399, 254, 453, 243
      Annotation: 
       Subtype: Link
       Rect: 472, 216, 549, 205
      Annotation: 
       Subtype: Link
       Rect: 469, 187, 533, 177
      Annotation: 
       Subtype: Link
       Rect: 408, 149, 491, 139
      Annotation: 
       Subtype: Link
       Rect: 523, 121, 549, 110
      Annotation: 
       Subtype: Link
       Rect: 315, 111, 361, 101
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 18
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 68, 709, 139, 699
      Annotation: 
       Subtype: Link
       Rect: 139, 691, 204, 680
      Annotation: 
       Subtype: Link
       Rect: 97, 652, 189, 642
      Annotation: 
       Subtype: Link
       Rect: 104, 624, 179, 614
      Annotation: 
       Subtype: Link
       Rect: 55, 586, 132, 576
      Annotation: 
       Subtype: Link
       Rect: 214, 558, 273, 547
      Annotation: 
       Subtype: Link
       Rect: 165, 520, 267, 509
      Annotation: 
       Subtype: Link
       Rect: 185, 491, 277, 481
      Annotation: 
       Subtype: Link
       Rect: 86, 453, 149, 443
      Annotation: 
       Subtype: Link
       Rect: 97, 415, 172, 405
      Annotation: 
       Subtype: Link
       Rect: 183, 387, 263, 376
      Annotation: 
       Subtype: Link
       Rect: 160, 349, 230, 338
      Annotation: 
       Subtype: Link
       Rect: 153, 330, 210, 319
      Annotation: 
       Subtype: Link
       Rect: 150, 301, 277, 291
      Annotation: 
       Subtype: Link
       Rect: 55, 272, 131, 262
      Annotation: 
       Subtype: Link
       Rect: 55, 234, 118, 224
      Annotation: 
       Subtype: Link
       Rect: 55, 196, 145, 186
      Annotation: 
       Subtype: Link
       Rect: 146, 168, 223, 158
      Annotation: 
       Subtype: Link
       Rect: 226, 140, 283, 129
      Annotation: 
       Subtype: Link
       Rect: 55, 111, 138, 101
      Annotation: 
       Subtype: Link
       Rect: 393, 710, 491, 699
      Annotation: 
       Subtype: Link
       Rect: 474, 691, 549, 680
      Annotation: 
       Subtype: Link
       Rect: 418, 653, 517, 642
      Annotation: 
       Subtype: Link
       Rect: 315, 605, 523, 595
      Annotation: 
       Subtype: Link
       Rect: 315, 567, 423, 557
      Annotation: 
       Subtype: Link
       Rect: 427, 529, 527, 519
      Annotation: 
       Subtype: Link
       Rect: 432, 501, 530, 490
      Annotation: 
       Subtype: Link
       Rect: 443, 434, 526, 424
      Annotation: 
       Subtype: Link
       Rect: 427, 396, 527, 386
      Annotation: 
       Subtype: Link
       Rect: 368, 348, 465, 338
      Annotation: 
       Subtype: Link
       Rect: 457, 320, 544, 310
      Annotation: 
       Subtype: Link
       Rect: 404, 282, 479, 272
      Annotation: 
       Subtype: Link
       Rect: 520, 254, 549, 243
      Annotation: 
       Subtype: Link
       Rect: 315, 244, 363, 234
      Annotation: 
       Subtype: Link
       Rect: 328, 215, 392, 205
      Annotation: 
       Subtype: Link
       Rect: 475, 197, 547, 186
      Annotation: 
       Subtype: Link
       Rect: 413, 168, 497, 158
      Annotation: 
       Subtype: Link
       Rect: 361, 139, 460, 129
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 19
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 97, 709, 198, 699
      Annotation: 
       Subtype: Link
       Rect: 176, 672, 225, 661
      Annotation: 
       Subtype: Link
       Rect: 136, 634, 219, 623
      Annotation: 
       Subtype: Link
       Rect: 138, 586, 201, 576
      Annotation: 
       Subtype: Link
       Rect: 114, 538, 223, 528
      Annotation: 
       Subtype: Link
       Rect: 97, 500, 199, 490
      Annotation: 
       Subtype: Link
       Rect: 118, 453, 212, 443
      Annotation: 
       Subtype: Link
       Rect: 55, 415, 163, 405
      Annotation: 
       Subtype: Link
       Rect: 55, 386, 145, 376
      Annotation: 
       Subtype: Link
       Rect: 174, 358, 228, 348
      Annotation: 
       Subtype: Link
       Rect: 161, 330, 207, 319
      Annotation: 
       Subtype: Link
       Rect: 55, 301, 152, 291
      Annotation: 
       Subtype: Link
       Rect: 55, 263, 132, 253
      Annotation: 
       Subtype: Link
       Rect: 212, 225, 280, 215
      Annotation: 
       Subtype: Link
       Rect: 68, 196, 142, 186
      Annotation: 
       Subtype: Link
       Rect: 68, 168, 120, 158
      Annotation: 
       Subtype: Link
       Rect: 114, 120, 212, 110
      Annotation: 
       Subtype: Link
       Rect: 118, 82, 212, 72
      Annotation: 
       Subtype: Link
       Rect: 448, 700, 500, 690
      Annotation: 
       Subtype: Link
       Rect: 513, 672, 549, 661
      Annotation: 
       Subtype: Link
       Rect: 315, 662, 354, 652
      Annotation: 
       Subtype: Link
       Rect: 328, 605, 405, 595
      Annotation: 
       Subtype: Link
       Rect: 315, 567, 393, 557
      Annotation: 
       Subtype: Link
       Rect: 365, 529, 466, 519
      Annotation: 
       Subtype: Link
       Rect: 410, 482, 508, 471
      Annotation: 
       Subtype: Link
       Rect: 346, 443, 401, 433
      Annotation: 
       Subtype: Link
       Rect: 465, 406, 535, 395
      Annotation: 
       Subtype: Link
       Rect: 315, 358, 410, 348
      Annotation: 
       Subtype: Link
       Rect: 315, 310, 413, 300
      Annotation: 
       Subtype: Link
       Rect: 523, 282, 549, 272
      Annotation: 
       Subtype: Link
       Rect: 315, 272, 373, 262
      Annotation: 
       Subtype: Link
       Rect: 523, 235, 549, 224
      Annotation: 
       Subtype: Link
       Rect: 315, 225, 387, 215
      Annotation: 
       Subtype: Link
       Rect: 389, 197, 438, 186
      Annotation: 
       Subtype: Link
       Rect: 448, 159, 539, 148
      Annotation: 
       Subtype: Link
       Rect: 410, 121, 504, 110
      Annotation: 
       Subtype: Link
       Rect: 443, 102, 504, 91
      Annotation: 
       Subtype: Link
       Rect: 433, 83, 527, 72
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 20
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 122, 690, 199, 680
      Annotation: 
       Subtype: Link
       Rect: 68, 662, 165, 652
      Annotation: 
       Subtype: Link
       Rect: 137, 624, 231, 614
      Annotation: 
       Subtype: Link
       Rect: 104, 595, 167, 585
      Annotation: 
       Subtype: Link
       Rect: 182, 567, 279, 557
      Annotation: 
       Subtype: Link
       Rect: 177, 538, 229, 528
      Annotation: 
       Subtype: Link
       Rect: 150, 510, 211, 500
      Annotation: 
       Subtype: Link
       Rect: 82, 481, 170, 471
      Annotation: 
       Subtype: Link
       Rect: 68, 443, 123, 433
      Annotation: 
       Subtype: Link
       Rect: 155, 367, 265, 357
      Annotation: 
       Subtype: Link
       Rect: 259, 339, 288, 329
      Annotation: 
       Subtype: Link
       Rect: 55, 329, 102, 319
      Annotation: 
       Subtype: Link
       Rect: 114, 291, 194, 281
      Annotation: 
       Subtype: Link
       Rect: 92, 253, 183, 243
      Annotation: 
       Subtype: Link
       Rect: 55, 225, 149, 215
      Annotation: 
       Subtype: Link
       Rect: 124, 187, 225, 177
      Annotation: 
       Subtype: Link
       Rect: 216, 158, 272, 148
      Annotation: 
       Subtype: Link
       Rect: 111, 139, 188, 129
      Annotation: 
       Subtype: Link
       Rect: 166, 101, 264, 91
      Annotation: 
       Subtype: Link
       Rect: 427, 710, 527, 699
      Annotation: 
       Subtype: Link
       Rect: 375, 643, 443, 633
      Annotation: 
       Subtype: Link
       Rect: 418, 615, 481, 604
      Annotation: 
       Subtype: Link
       Rect: 443, 596, 523, 585
      Annotation: 
       Subtype: Link
       Rect: 379, 567, 460, 557
      Annotation: 
       Subtype: Link
       Rect: 459, 501, 545, 490
      Annotation: 
       Subtype: Link
       Rect: 403, 463, 480, 452
      Annotation: 
       Subtype: Link
       Rect: 478, 434, 549, 424
      Annotation: 
       Subtype: Link
       Rect: 372, 405, 449, 395
      Annotation: 
       Subtype: Link
       Rect: 315, 367, 410, 357
      Annotation: 
       Subtype: Link
       Rect: 328, 310, 412, 300
      Annotation: 
       Subtype: Link
       Rect: 506, 282, 549, 272
      Annotation: 
       Subtype: Link
       Rect: 315, 272, 373, 262
      Annotation: 
       Subtype: Link
       Rect: 458, 244, 526, 234
      Annotation: 
       Subtype: Link
       Rect: 395, 216, 454, 205
      Annotation: 
       Subtype: Link
       Rect: 415, 178, 495, 167
      Annotation: 
       Subtype: Link
       Rect: 523, 149, 549, 139
      Annotation: 
       Subtype: Link
       Rect: 315, 139, 393, 129
      Annotation: 
       Subtype: Link
       Rect: 520, 111, 549, 101
      Annotation: 
       Subtype: Link
       Rect: 315, 101, 371, 91
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 21
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 55, 709, 156, 699
      Annotation: 
       Subtype: Link
       Rect: 205, 634, 282, 623
      Annotation: 
       Subtype: Link
       Rect: 220, 605, 283, 595
      Annotation: 
       Subtype: Link
       Rect: 263, 586, 288, 576
      Annotation: 
       Subtype: Link
       Rect: 55, 576, 109, 566
      Annotation: 
       Subtype: Link
       Rect: 128, 539, 229, 528
      Annotation: 
       Subtype: Link
       Rect: 179, 520, 231, 509
      Annotation: 
       Subtype: Link
       Rect: 222, 491, 274, 481
      Annotation: 
       Subtype: Link
       Rect: 89, 462, 140, 452
      Annotation: 
       Subtype: Link
       Rect: 114, 424, 174, 414
      Annotation: 
       Subtype: Link
       Rect: 218, 406, 288, 395
      Annotation: 
       Subtype: Link
       Rect: 55, 367, 99, 357
      Annotation: 
       Subtype: Link
       Rect: 219, 339, 283, 329
      Annotation: 
       Subtype: Link
       Rect: 181, 301, 244, 291
      Annotation: 
       Subtype: Link
       Rect: 196, 263, 280, 253
      Annotation: 
       Subtype: Link
       Rect: 169, 235, 232, 224
      Annotation: 
       Subtype: Link
       Rect: 263, 216, 288, 205
      Annotation: 
       Subtype: Link
       Rect: 55, 206, 128, 196
      Annotation: 
       Subtype: Link
       Rect: 119, 120, 229, 110
      Annotation: 
       Subtype: Link
       Rect: 143, 83, 198, 72
      Annotation: 
       Subtype: Link
       Rect: 506, 700, 549, 690
      Annotation: 
       Subtype: Link
       Rect: 315, 690, 373, 680
      Annotation: 
       Subtype: Link
       Rect: 379, 652, 472, 642
      Annotation: 
       Subtype: Link
       Rect: 328, 614, 378, 604
      Annotation: 
       Subtype: Link
       Rect: 375, 576, 455, 566
      Annotation: 
       Subtype: Link
       Rect: 368, 538, 466, 528
      Annotation: 
       Subtype: Link
       Rect: 490, 501, 549, 490
      Annotation: 
       Subtype: Link
       Rect: 315, 491, 353, 481
      Annotation: 
       Subtype: Link
       Rect: 422, 463, 505, 452
      Annotation: 
       Subtype: Link
       Rect: 328, 424, 429, 414
      Annotation: 
       Subtype: Link
       Rect: 450, 396, 513, 386
      Annotation: 
       Subtype: Link
       Rect: 389, 368, 435, 357
      Annotation: 
       Subtype: Link
       Rect: 315, 339, 413, 329
      Annotation: 
       Subtype: Link
       Rect: 328, 291, 383, 281
      Annotation: 
       Subtype: Link
       Rect: 328, 263, 412, 253
      Annotation: 
       Subtype: Link
       Rect: 449, 235, 527, 224
      Annotation: 
       Subtype: Link
       Rect: 511, 187, 549, 177
      Annotation: 
       Subtype: Link
       Rect: 315, 177, 376, 167
      Annotation: 
       Subtype: Link
       Rect: 523, 149, 549, 139
      Annotation: 
       Subtype: Link
       Rect: 315, 139, 359, 129
      Annotation: 
       Subtype: Link
       Rect: 315, 101, 393, 91
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 22
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 68, 709, 142, 699
      Annotation: 
       Subtype: Link
       Rect: 192, 672, 285, 661
      Annotation: 
       Subtype: Link
       Rect: 55, 633, 156, 623
      Annotation: 
       Subtype: Link
       Rect: 176, 596, 269, 585
      Annotation: 
       Subtype: Link
       Rect: 114, 557, 209, 547
      Annotation: 
       Subtype: Link
       Rect: 104, 519, 198, 509
      Annotation: 
       Subtype: Link
       Rect: 107, 481, 194, 471
      Annotation: 
       Subtype: Link
       Rect: 151, 453, 228, 443
      Annotation: 
       Subtype: Link
       Rect: 55, 415, 155, 405
      Annotation: 
       Subtype: Link
       Rect: 259, 387, 288, 376
      Annotation: 
       Subtype: Link
       Rect: 55, 377, 120, 367
      Annotation: 
       Subtype: Link
       Rect: 217, 349, 280, 338
      Annotation: 
       Subtype: Link
       Rect: 67, 310, 185, 300
      Annotation: 
       Subtype: Link
       Rect: 230, 282, 279, 272
      Annotation: 
       Subtype: Link
       Rect: 194, 244, 288, 234
      Annotation: 
       Subtype: Link
       Rect: 263, 216, 288, 205
      Annotation: 
       Subtype: Link
       Rect: 55, 206, 123, 196
      Annotation: 
       Subtype: Link
       Rect: 237, 178, 287, 167
      Annotation: 
       Subtype: Link
       Rect: 210, 149, 273, 139
      Annotation: 
       Subtype: Link
       Rect: 86, 111, 138, 101
      Annotation: 
       Subtype: Link
       Rect: 68, 82, 165, 72
      Annotation: 
       Subtype: Link
       Rect: 421, 700, 519, 690
      Annotation: 
       Subtype: Link
       Rect: 457, 681, 507, 671
      Annotation: 
       Subtype: Link
       Rect: 449, 662, 533, 652
      Annotation: 
       Subtype: Link
       Rect: 315, 633, 406, 623
      Annotation: 
       Subtype: Link
       Rect: 523, 615, 549, 604
      Annotation: 
       Subtype: Link
       Rect: 315, 605, 423, 595
      Annotation: 
       Subtype: Link
       Rect: 315, 567, 410, 557
      Annotation: 
       Subtype: Link
       Rect: 455, 539, 549, 528
      Annotation: 
       Subtype: Link
       Rect: 357, 510, 434, 500
      Annotation: 
       Subtype: Link
       Rect: 490, 472, 549, 462
      Annotation: 
       Subtype: Link
       Rect: 315, 462, 355, 452
      Annotation: 
       Subtype: Link
       Rect: 523, 434, 549, 424
      Annotation: 
       Subtype: Link
       Rect: 315, 424, 362, 414
      Annotation: 
       Subtype: Link
       Rect: 328, 396, 405, 386
      Annotation: 
       Subtype: Link
       Rect: 473, 358, 549, 348
      Annotation: 
       Subtype: Link
       Rect: 315, 320, 413, 310
      Annotation: 
       Subtype: Link
       Rect: 523, 301, 549, 291
      Annotation: 
       Subtype: Link
       Rect: 315, 291, 377, 281
      Annotation: 
       Subtype: Link
       Rect: 368, 253, 466, 243
      Annotation: 
       Subtype: Link
       Rect: 375, 215, 475, 205
      Annotation: 
       Subtype: Link
       Rect: 379, 177, 473, 167
      Annotation: 
       Subtype: Link
       Rect: 375, 139, 475, 129
      Annotation: 
       Subtype: Link
       Rect: 328, 82, 384, 72
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 23
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 86, 690, 154, 680
      Annotation: 
       Subtype: Link
       Rect: 55, 652, 118, 642
      Annotation: 
       Subtype: Link
       Rect: 68, 614, 162, 604
      Annotation: 
       Subtype: Link
       Rect: 263, 586, 288, 576
      Annotation: 
       Subtype: Link
       Rect: 55, 576, 104, 566
      Annotation: 
       Subtype: Link
       Rect: 263, 548, 288, 538
      Annotation: 
       Subtype: Link
       Rect: 55, 538, 123, 528
      Annotation: 
       Subtype: Link
       Rect: 104, 510, 175, 500
      Annotation: 
       Subtype: Link
       Rect: 197, 482, 278, 471
      Annotation: 
       Subtype: Link
       Rect: 236, 463, 286, 452
      Annotation: 
       Subtype: Link
       Rect: 263, 425, 288, 414
      Annotation: 
       Subtype: Link
       Rect: 55, 415, 112, 405
      Annotation: 
       Subtype: Link
       Rect: 86, 386, 162, 376
      Annotation: 
       Subtype: Link
       Rect: 107, 358, 187, 348
      Annotation: 
       Subtype: Link
       Rect: 189, 330, 280, 319
      Annotation: 
       Subtype: Link
       Rect: 262, 301, 288, 291
      Annotation: 
       Subtype: Link
       Rect: 55, 291, 121, 281
      Annotation: 
       Subtype: Link
       Rect: 161, 244, 242, 234
      Annotation: 
       Subtype: Link
       Rect: 181, 206, 265, 196
      Annotation: 
       Subtype: Link
       Rect: 197, 168, 279, 158
      Annotation: 
       Subtype: Link
       Rect: 262, 130, 288, 120
      Annotation: 
       Subtype: Link
       Rect: 55, 120, 108, 110
      Annotation: 
       Subtype: Link
       Rect: 375, 700, 471, 690
      Annotation: 
       Subtype: Link
       Rect: 379, 662, 473, 652
      Annotation: 
       Subtype: Link
       Rect: 328, 624, 430, 614
      Annotation: 
       Subtype: Link
       Rect: 454, 577, 500, 566
      Annotation: 
       Subtype: Link
       Rect: 522, 548, 549, 538
      Annotation: 
       Subtype: Link
       Rect: 315, 538, 362, 528
      Annotation: 
       Subtype: Link
       Rect: 432, 510, 540, 500
      Annotation: 
       Subtype: Link
       Rect: 471, 482, 533, 471
      Annotation: 
       Subtype: Link
       Rect: 406, 444, 508, 433
      Annotation: 
       Subtype: Link
       Rect: 489, 415, 539, 405
      Annotation: 
       Subtype: Link
       Rect: 328, 377, 415, 367
      Annotation: 
       Subtype: Link
       Rect: 376, 349, 467, 338
      Annotation: 
       Subtype: Link
       Rect: 328, 320, 433, 310
      Annotation: 
       Subtype: Link
       Rect: 411, 282, 511, 272
      Annotation: 
       Subtype: Link
       Rect: 474, 263, 549, 253
      Annotation: 
       Subtype: Link
       Rect: 343, 215, 426, 205
      Annotation: 
       Subtype: Link
       Rect: 523, 187, 549, 177
      Annotation: 
       Subtype: Link
       Rect: 315, 177, 387, 167
      Annotation: 
       Subtype: Link
       Rect: 428, 149, 503, 139
      Annotation: 
       Subtype: Link
       Rect: 328, 92, 442, 82
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
    Page: 
     Sequence: 24
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 117, 691, 214, 680
      Annotation: 
       Subtype: Link
       Rect: 55, 652, 105, 642
      Annotation: 
       Subtype: Link
       Rect: 168, 634, 244, 623
      Annotation: 
       Subtype: Link
       Rect: 262, 586, 288, 576
      Annotation: 
       Subtype: Link
       Rect: 55, 576, 129, 566
      Annotation: 
       Subtype: Link
       Rect: 262, 548, 288, 538
      Annotation: 
       Subtype: Link
       Rect: 55, 538, 129, 528
      Annotation: 
       Subtype: Link
       Rect: 176, 501, 256, 490
      Annotation: 
       Subtype: Link
       Rect: 150, 463, 252, 452
      Annotation: 
       Subtype: Link
       Rect: 365, 700, 446, 690
      Annotation: 
       Subtype: Link
       Rect: 392, 672, 448, 661
      Annotation: 
       Subtype: Link
       Rect: 433, 643, 507, 633
      Annotation: 
       Subtype: Link
       Rect: 328, 605, 411, 595
      Annotation: 
       Subtype: Link
       Rect: 430, 577, 493, 566
      Annotation: 
       Subtype: Link
       Rect: 525, 510, 549, 500
      Annotation: 
       Subtype: Link
       Rect: 305, 501, 422, 490
      Annotation: 
       Subtype: Link
       Rect: 45, 38, 104, 30
      Annotation: 
       Subtype: Link
       Rect: 112, 38, 168, 30
      Annotation: 
       Subtype: Link
       Rect: 419, 39, 551, 30
  Checksum: c004713d
   Type: CRC32
  Checksum: b4693dc21388f9e681c7a85c6b390bf3
   Type: MD5
  Checksum: 100754f022c951dd026ba8f1423a0f01e0180f4a
   Type: SHA-1