1a4bf4732bef71ca6375f498ac3d12ac pdf_223746.pdf 765907df3b02b45b9804676e10b8945f762a81ba pdf_223746.pdf 7cb1e112583a59c99a2cd6b74d851d2860180b04def1e7c188f7b4f1c7b79bea pdf_223746.pdf Title: First Universal Newborn Screening Program for Severe Combined Immunodeficiency in Europe. Two-Years' Experience in Catalonia (Spain) Subject: Severe combined immunodeficiency (SCID), the most severe form of T-cell immunodeficiency, can be screened at birth by quantifying T-cell receptor excision circles (TRECs) in dried blood spot (DBS) samples. Keywords: newborn screening, severe combined immunodeficiency, T-cell receptor excision circles, T-cell receptor, T-lymphocytes, stem cell transplantation Author: Pere Soler-Palacı́n Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Oct 22 11:42:51 2019 CEST ModDate: Mon Apr 26 11:13:02 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 844394 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GNGMVL+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 276 0 JGSKGJ+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 280 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 287 0 CZBYQS+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 291 0 SLAHXP+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 295 0 PDGKTU+MTGU Type 1C Custom yes yes no 301 0 SBAJBL+MTSY Type 1C Custom yes yes no 305 0 OXLZAA+MinionPro-It Type 1C Custom yes yes no 210 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 214 0 ZYIPGX+MinionPro-Bold Type 1C Custom yes yes no 204 0 GBQXXP+MinionPro-Regular Type 1C Custom yes yes no 203 0 UADLTO+MTSYB Type 1C Custom yes yes no 221 0 CNBJKM+MTGUB Type 1C Custom yes yes no 222 0 CDERZY+TimesNewRomanPS-BoldMT Type 1C WinAnsi yes yes no 231 0 ZVHAAE+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 229 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-04-29 02:33:57 CEST RepresentationInformation: pdf_223746.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-04-26 11:28:54 CEST Size: 844394 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 334 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: First Universal Newborn Screening Program for Severe Combined Immunodeficiency in Europe. Two-Years' Experience in Catalonia (匀瀀愀椀渀㸾൥湤潢樍㌱㔠〠潢樍㰼⽁捴楯港䝯呯⽄敳琯獥捴楯渪⸲⽎數琠㌲㘠〠刯偡牥湴″ㄴ‰⁒⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㌱㘠〠潢樍㰼⽁捴楯港䝯呯⽄敳琯獥捴楯渪⸱㤯偡牥湴″ㄴ‰⁒⽐牥瘠㌱㜠〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: Population and Data Collection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Sample Testing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Definition and Interpretation of Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Initial Clinical and Immunological Assessment at SCID-CRU Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Demographics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Cutoff Values and Rates Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Positive Detections Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Info: Title: First Universal Newborn Screening Program for Severe Combined Immunodeficiency in Europe. Two-Years' Experience in Catalonia (Spain) Author: Pere Soler-Palacı́n Subject: Severe combined immunodeficiency (SCID), the most severe form of T-cell immunodeficiency, can be screened at birth by quantifying T-cell receptor excision circles (TRECs) in dried blood spot (DBS) samples. 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Two-Years' Experience in Catalonia (Spain) Pere Soler-Palacı́n Severe combined immunodeficiency (SCID), the most severe form of T-cell immunodeficiency, can be screened at birth by quantifying T-cell receptor excision circles (TRECs) in dried blood spot (DBS) samples. Severe combined immunodeficiency (SCID), the most severe form of T-cell immunodeficiency, can be screened at birth by quantifying T-cell receptor excision circles (TRECs) in dried blood spot (DBS) samples. newborn screening severe combined immunodeficiency T-cell receptor excision circles T-cell receptor T-lymphocytes stem cell transplantation Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 161, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 464, 728, 507, 736 Annotation: Subtype: Link Rect: 507, 729, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 451, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 117, 38 Annotation: Subtype: Link Rect: 120, 30, 180, 38 Annotation: Subtype: Link Rect: 428, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 513, 160, 523 Annotation: Subtype: Link Rect: 99, 345, 160, 354 Annotation: 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