3dbef769c391940311636a7fa358345e pmc_30606734.pdf 7f55f04c7e7d7fa33d16aa229e300c8b31f4a6fe pmc_30606734.pdf 4a600e71c83d89320373c61e7fd1b4e7074b82a94d345b93535df5772c8a8956 pmc_30606734.pdf Title: Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid* Subject: , 18 (2019) 546-560. doi:10.1074/mcp.RA118.001290 Keywords: Selected reaction monitoring; Clinical proteomics; Alzheimer's disease; Biomarker: Prognostic; Cerebrospinal fluid Author: Alberto Lleó Creator: Elsevier Producer: iTextSharp™ 5.5.13.1 ©2000-2019 iText Group NV (AGPL-version); modified using iTextSharp™ 5.5.13.1 ©2000-2019 iText Group NV (AGPL-version) CreationDate: Mon Sep 21 14:32:31 2020 CEST ModDate: Mon Sep 21 14:32:31 2020 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 594 x 783 pts Page rot: 0 File size: 1821522 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- APJZEY+TimesNewRomanPSMT TrueType WinAnsi yes yes no 232 0 IEGLJP+HelveticaNeue-Bold Type 1C WinAnsi yes yes no 237 0 IEGLMA+HelveticaNeue-Roman Type 1C WinAnsi yes yes no 239 0 IEGPDA+Symbol Type 1C Custom yes yes yes 242 0 IEGPEI+HelveticaNeue-BoldItalic Type 1C WinAnsi yes yes no 244 0 IEGPOB+MathematicalPi-Three Type 1C Custom yes yes no 194 0 IEHBOD+MathematicalPi-Four Type 1C Custom yes yes no 96 0 IEHBPB+Dutch801BT-Bold Type 1C WinAnsi yes yes no 98 0 IEHCAD+MathematicalPi-One Type 1C Custom yes yes no 197 0 IEHCNN+HelveticaNeue-Italic Type 1C WinAnsi yes yes no 202 0 IEHCOK+Universal-GreekwithMathPi Type 1C Custom yes yes no 199 0 IEIFDC+Universal-NewswithCommPi Type 1C Custom yes yes yes 174 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-01-23 02:56:21 CET RepresentationInformation: pmc_30606734.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-01-22 09:29:32 CET Size: 1821522 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid* Children: Item: Title: EXPERIMENTAL PROCEDURES Item: Title: RESULTS Item: Title: DISCUSSION Item: Title: Acknowledgments Item: Title: DATA AVAILABILITY Item: Title: REFERENCES Filters: FilterPipeline: FlateDecode Fonts: TrueType: Font: BaseFont: APJZEY+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: APJZEY+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -306, 2000, 1006 FontFile2: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1074/mcp.RA118.001290 Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid* Alberto Lleó Raúl Núñez-Llaves Daniel Alcolea Cristina Chiva Daniel Balateu-Paños Martí Colom-Cadena Gemma Gomez-Giro Laia Muñoz Marta Querol-Vilaseca Jordi Pegueroles Lorena Rami Albert Lladó José L. Molinuevo Mikel Tainta Jordi Clarimón Tara Spires-Jones Rafael Blesa Juan Fortea Pablo Martínez-Lage Raquel Sánchez-Valle Eduard Sabidó Àlex Bayés Olivia Belbin , 18 (2019) 546-560. doi:10.1074/mcp.RA118.001290 © 2019 Lleó et al. Selected reaction monitoring Clinical proteomics Alzheimer's disease Biomarker: Prognostic Cerebrospinal fluid journal Copyright © 2019 © 2019 Lleó et al.. 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