304310e185cb1e5509d35ecfcd0e83a3 223863.pdf 29fd46f1df190a8e1c237a98185812931e23ef32 223863.pdf 3b6f7a43341f181a300f5ac96e2eb026317f177241e10687f89e6c238f13b498 223863.pdf Title: Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study Subject: Journal of Thoracic Oncology, 14 (2019) 2120-2132. doi:10.1016/j.jtho.2019.07.005 Author: Esther Conde MD PhD Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: 16th November 2019 ModDate: Tue Nov 19 10:03:37 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 584.957 x 782.986 pts Page rot: 0 File size: 2227182 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LAKKBP+AdvTTc9c3bd71 Type 1C WinAnsi yes yes no 882 0 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib12' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib12' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fna' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fnb' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl2fnc' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib18' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib19' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib29' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib12' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib10' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib35' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib24' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib24' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib22' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib38' cannot be found Offset: 2192200 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 2192200 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 963 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Material and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: Study Design and Tumor Samples Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: FISH for ROS1 Rearrangements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: IHC for ROS1 Expression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: NGS for ROS1 Rearrangements Destination: 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edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Supplementary Data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Info: Title: Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study Author: Esther Conde MD PhD Subject: Journal of Thoracic Oncology, 14 (2019) 2120-2132. doi:10.1016/j.jtho.2019.07.005 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) ID: 0x5b7e16cb9f5ab0b724713e0912012f26, 0xcd92ad9258640342820cc9f74f6f2a50 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 524 ImageHeight: 148 ColorSpace: palette color 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Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study Esther Conde MD PhD Susana Hernandez PhD Rebeca Martinez Barbara Angulo PhD Javier De Castro MD PhD Ana Collazo-Lorduy MD PhD Beatriz Jimenez MD Alfonso Muriel PhD Jose Luis Mate MD Teresa Moran MD Ignacio Aranda MD PhD Bartomeu Massuti MD Federico Rojo MD PhD Manuel Domine MD PhD Irene Sansano MD Felip Garcia MD Enriqueta Felip MD PhD Nuria Mancheño MD Oscar Juan MD PhD Julian Sanz MD PhD Jose Luis Gonzalez-Larriba MD PhD Lidia Atienza-Cuevas MD Esperanza Arriola-Arellano MD Ihab Abdulkader MD Jorge Garcia-Gonzalez MD Carmen Camacho MD Delvys Rodriguez-Abreu MD Cristina Teixido PhD Noemi Reguart MD PhD Ana Gonzalez-Piñeiro MD Martin Lazaro-Quintela MD Maria Dolores Lozano MD PhD Alfonso Gurpide MD Javier Gomez-Roman MD PhD Marta Lopez-Brea MD Lara Pijuan MD PhD Marta Salido PhD Edurne Arriola MD PhD Amparo Company MD Amelia Insa MD Isabel Esteban-Rodriguez MD PhD Monica Saiz MD Eider Azkona MD Ramiro Alvarez MD Angel Artal MD PhD Maria Luz Plaza MD PhD David Aguiar MD Ana Belen Enguita MD Amparo Benito MD Luis Paz-Ares MD PhD Pilar Garrido MD PhD Fernando Lopez-Rios MD PhD ROS1 Immunohistochemistry FISH Next-generation sequencing Lung carcinoma Journal of Thoracic Oncology, 14 (2019) 2120-2132. doi:10.1016/j.jtho.2019.07.005 Elsevier Inc journal Journal of Thoracic Oncology © 2019 International Association for the Study of Lung Cancer. 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Annotation: Subtype: Link Rect: 315, 573, 540, 582 Annotation: Subtype: Link Rect: 315, 562, 447, 571 Annotation: Subtype: Link Rect: 315, 551, 539, 560 Annotation: Subtype: Link Rect: 315, 540, 540, 549 Annotation: Subtype: Link Rect: 315, 529, 540, 538 Annotation: Subtype: Link Rect: 315, 518, 330, 527 Annotation: Subtype: Link Rect: 315, 507, 540, 516 Annotation: Subtype: Link Rect: 315, 496, 540, 505 Annotation: Subtype: Link Rect: 315, 485, 540, 494 Annotation: Subtype: Link Rect: 315, 474, 419, 483 Annotation: Subtype: Link Rect: 315, 463, 540, 472 Annotation: Subtype: Link Rect: 315, 452, 540, 461 Annotation: Subtype: Link Rect: 315, 441, 540, 450 Annotation: Subtype: Link Rect: 315, 430, 539, 439 Annotation: Subtype: Link Rect: 315, 420, 443, 428 Annotation: Subtype: Link Rect: 315, 409, 540, 418 Annotation: Subtype: Link Rect: 315, 398, 539, 407 Annotation: Subtype: Link Rect: 315, 387, 540, 396 Annotation: Subtype: Link Rect: 315, 376, 540, 385 Annotation: Subtype: Link Rect: 315, 365, 540, 374 Annotation: Subtype: Link Rect: 315, 354, 395, 363 Checksum: 2a3454e7 Type: CRC32 Checksum: 304310e185cb1e5509d35ecfcd0e83a3 Type: MD5 Checksum: 29fd46f1df190a8e1c237a98185812931e23ef32 Type: SHA-1