f7eb4a223bd1ed74035b0e7de374ea09 JNB_a2019v64p218.pdf e428d9bac3dd02c3e824503d34d3e3e2be75530d JNB_a2019v64p218.pdf 9cf112f7a7b697b8b85d8ec2e24a21f81d32d7189308cde9b4e5a5706361659c JNB_a2019v64p218.pdf Title: A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways Subject: The Journal of Nutritional Biochemistry, 64 (2019) 218-227. doi:10.1016/j.jnutbio.2018.11.001 Keywords: Dietary lipids; Breast cancer; Olive oil; Transcriptome; Immune system; Apoptosis; Metabolism Author: Raquel Escrich Creator: Elsevier Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Mon Jan 14 03:50:48 2019 CET ModDate: Fri Feb 1 10:21:38 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 593.972 x 792 pts Page rot: 0 File size: 2095199 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HHELJA+AdvTT5235d5a9 Type 1C WinAnsi yes yes no 410 0 HHELJB+AdvTT5235d5a9+26 Type 1C Custom yes yes yes 411 0 HHELJC+AdvTT5235d5a9+20 Type 1C Custom yes yes yes 412 0 HHELJD+AdvTT94c8263f.I Type 1C WinAnsi yes yes no 413 0 HHELKD+AdvTT28000ce1.B Type 1C WinAnsi yes yes no 414 0 HHELKE+AdvTT5235d5a9+03 Type 1C Custom yes yes yes 424 0 HHELKF+AdvTT5235d5a9+fb Type 1C Custom yes yes yes 430 0 HHELPE+AdvTT153188ed Type 1C WinAnsi yes yes no 438 0 HHELPF+AdvTT4844d391.B Type 1C WinAnsi yes yes no 439 0 HHEMJD+AdvTT5235d5a9+22 Type 1C Custom yes yes no 247 0 HHEMKD+AdvTT454a7a89 Type 1C WinAnsi yes yes no 256 0 HHEMKE+AdvTT94c8263f.I+20 Type 1C WinAnsi yes yes no 253 0 HHENIA+AdvTT94c8263f.I+03 Type 1C Custom yes yes yes 259 0 HHFDGN+AdvTT1753cc9b.BI+03 Type 1C Custom yes yes yes 262 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-25 02:25:07 CET RepresentationInformation: JNB_a2019v64p218.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-02-24 12:53:27 CET Size: 2095199 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0005' cannot be found Offset: 2075403 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0010' cannot be found Offset: 2075403 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0015' cannot be found Offset: 2075403 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0020' cannot be found Offset: 2075403 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0025' cannot be found Offset: 2075403 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'em0030' cannot be found Offset: 2075403 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 501 FreeObjects: 12 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect... Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: 2. Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: 2.1. Diets Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: 2.2. Animals and experimental design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 2.3. Characterization of tumor malignant phenotype and tumor growth Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 2.4. RNA extraction and microarrays analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 2.5. Reverse transcription and real-time PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: 2.6. Protein extraction and Western blot Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 2.7. Immunohistochemistry and quantification of immunoreactivity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: 2.8. Circulating levels of cytokines Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: 2.9. Hormone levels Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 2.10. Metabolic parameters Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: 2.11. Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 3. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Children: Item: Title: 3.1. High-fat diets differentially influence tumor malignant phenotype and tumor growth Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 3.2. High-fat diets differentially modify the gene expression profile of the experimental tumors Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 3.3. Validation of gene expression profiles and protein expression analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: 3.4. High-fat diets differentially modulate tumor infiltration of cytotoxic lymphocytes and immunosuppressive mechanisms Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 3.5. Dietary lipids influence circulating levels of inflammatory cytokines Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 3.6. Dietary lipids effects in other systemic factors Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 4. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Info: Title: A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways Author: Raquel Escrich Subject: The Journal of Nutritional Biochemistry, 64 (2019) 218-227. doi:10.1016/j.jnutbio.2018.11.001 Keywords: Dietary lipids; Breast cancer; Olive oil; Transcriptome; Immune system; Apoptosis; Metabolism Creator: Elsevier Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Mon Jan 14 03:50:48 CET 2019 ModDate: Fri Feb 01 10:21:38 CET 2019 ID: 0xd03c876ee826edd9276cd371595decaf, 0x6c395e58278e9949866539b54179bc86 Filters: FilterPipeline: 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metabolism, immune system function and proliferation/apoptosis pathways Raquel Escrich Irmgard Costa Montserrat Moreno Marta Cubedo Elena Vela Eduard Escrich Raquel Moral Dietary lipids Breast cancer Olive oil Transcriptome Immune system Apoptosis Metabolism The Journal of Nutritional Biochemistry, 64 (2019) 218-227. doi:10.1016/j.jnutbio.2018.11.001 The Authors journal The Journal of Nutritional Biochemistry (c) 2018 The Authors All rights reserved 0955-2863 64 C February 2019 2019-02 218-227 218 227 10.1016/j.jnutbio.2018.11.001 https://doi.org/10.1016/j.jnutbio.2018.11.001 2010-04-23 true 10.1016/j.jnutbio.2018.11.001 elsevier.com sciencedirect.com VoR 10.1016/j.jnutbio.2018.11.001 noindex 2010-04-23 true elsevier.com sciencedirect.com Elsevier 2019-01-14T10:50:48+08:00 2019-02-01T17:21:38+08:00 2019-02-01T17:21:38+08:00 True Dietary lipids; Breast cancer; Olive oil; Transcriptome; Immune system; Apoptosis; Metabolism Acrobat Distiller 10.0.0 (Windows) 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