372a689302db42a81c4cc9f9ba452513 FroImm_a2019v10p434.pdf dff5fd0eab6abaa62fce077057bc46ef4860c62f FroImm_a2019v10p434.pdf 65f680d875f73a53e85de180258e31585855f27b2d99a16f8daf4cb93d03cbe5 FroImm_a2019v10p434.pdf Title: Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis Subject: Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. Keywords: Atlantic salmon (Salmo salar), Piscirickettsiosis, immune evasion mechanisms, macrophages, lysosome, proteolytic activity Author: Sebastián Reyes-Cerpa Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Fri Mar 15 09:28:00 2019 CET ModDate: Tue Oct 5 15:20:02 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 3749983 bytes Optimized: yes PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XXYBAU+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 359 0 XJVVEZ+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 362 0 XUWDFG+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 364 0 KEGWPU+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 367 0 RKHPQK+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 369 0 EFWCSO+MTSY Type 1C Custom yes yes yes 372 0 KVHMWJ+MinionPro-It Type 1C Custom yes yes no 275 0 NYRJAS+MinionPro-Regular Type 1C Custom yes yes no 269 0 CNBJKM+MTGU Type 1C Custom yes yes no 274 0 HTDXAF+HelveticaNeueLTStd-Md Type 1C WinAnsi yes yes no 278 0 EACWSB+MinionPro-Bold Type 1C Custom yes yes no 280 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 288 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-10-06 02:47:35 CEST RepresentationInformation: FroImm_a2019v10p434.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-10-05 15:22:53 CEST Size: 3749983 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Children: Item: Title: Experimental Fish Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Isolation of Macrophages and Cell Culture Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Cultivation and Propagation of P. salmonis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Inactivation of P. salmonis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Detection of P. salmonis Using Quantitative Polymerase Chain Reaction (qPCR) Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Children: Item: Title: Fluorescein Isothiocyanate (FITC) Staining for P. salmonis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: P. salmonis Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Gentamicin Protection Assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Evaluation of Lysosomal Acidification Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Evaluation of Lysosomal Activity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Children: Item: Title: P. salmonis Infects Macrophage-Enriched Cell Cultures Obtained From Atlantic Salmon Head Kidneys Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Lysosomal Acidification Is Affected in P. salmonis-Infected Macrophage-Enriched Cell Cultures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Infection With P. salmonis Diminishes the Hydrolytic Activity in Macrophage-Enriched Cell Cultures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Data Availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2835 ImageHeight: 1985 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1890 ImageHeight: 1159 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3544 ImageHeight: 2191 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3544 ImageHeight: 1895 BitsPerSample: 8 BitsPerSampleUnit: integer 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true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: dvips + MiKTeX GPL Ghostscript 9.0 Atlantic salmon (Salmo salar), Piscirickettsiosis, immune evasion mechanisms, macrophages, lysosome, proteolytic activity 2021-10-05T15:20:02+02:00 2019-03-15T13:58+05:30 LaTeX with hyperref package + hypdvips 2021-10-05T15:20:02+02:00 be21ac70-4957-11e9-0000-44c39b6d4a4a uuid:de3b3521-e2d0-4f9b-966e-13bd5fe8186c application/pdf Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis Sebastián Reyes-Cerpa Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. Atlantic salmon (Salmo salar) Piscirickettsiosis immune evasion mechanisms macrophages lysosome proteolytic activity Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 161, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 470, 728, 513, 736 Annotation: Subtype: Link Rect: 513, 729, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 451, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 117, 38 Annotation: Subtype: Link Rect: 120, 30, 180, 38 Annotation: Subtype: Link Rect: 438, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 471, 160, 481 Annotation: Subtype: Link Rect: 78, 323, 160, 332 Annotation: Subtype: Link Rect: 74, 66, 160, 74 Annotation: Subtype: Link Rect: 176, 536, 551, 622 Annotation: Subtype: Link Rect: 176, 508, 265, 519 Annotation: Subtype: Link Rect: 276, 508, 381, 519 Annotation: Subtype: Link Rect: 176, 497, 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