49e2269278f8caeda70766010bca4132 226481.pdf bc8d1a5c041a04ff5ef2680579d30e89ad319ed8 226481.pdf 339c0c4cda977352e44988e569a8fc0f390ad5e35819b5af9fb0d462ac07197d 226481.pdf Title: Huge variation in obtaining ethical permission for a non-interventional observational study in Europe Subject: BMC Medical Ethics, 2019, doi:10.1186/s12910-019-0373-y Keywords: Author: Dylan W. de Lange Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Fri May 31 13:09:25 2019 CEST ModDate: Mon Jun 3 17:16:24 2019 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 664982 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-Regular Type 1 Custom yes no no 8 0 OPFBIJ+CfnvwxAdvTTe45e47d2 Type 1C WinAnsi yes yes no 13 0 OPFBLK+FjtktbAdvTT99c4c969 Type 1C WinAnsi yes yes no 11 0 OPFBJK+CvtycwAdvTTb5929f4c Type 1C WinAnsi yes yes no 29 0 OPFBLL+KcftpxAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 236 0 OPFBLM+KlbwrpAdvTT86d47313 Type 1C WinAnsi yes yes no 14 0 OPFBDK+XwgqjwAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 9 0 OPFCFJ+VxnjdqAdvTT7329fd89.I Type 1C WinAnsi yes yes no 15 0 OPFCHK+NbwnrpAdvTT86d47313+20 Type 1C WinAnsi yes yes no 10 0 OPFCHL+QmsgtnAdvTT8861b38f.I Type 1C WinAnsi yes yes no 12 0 OPFCIM+DgdbnfAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 30 0 HsghftHelvetica Type 1C WinAnsi yes no no 40 0 OPFCPL+TxtktqAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 61 0 OPFDCL+VcbcshAdvTTb5929f4c+22 Type 1C Custom yes yes yes 85 0 OPFDDM+DxsbxvAdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 86 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-12-06 02:32:07 CET RepresentationInformation: 226481.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-12-05 14:41:22 CET Size: 664982 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR3' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Tab1' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig2' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR8' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR9' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 400013 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 400013 MIMEtype: application/pdf PDFMetadata: Objects: 313 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Children: Item: Title: Definitions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Ethical clearance Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Authors’ contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Availability of data and materials Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Ethics approval and consent to participate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Consent for publication Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Author details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Publisher’s Note Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Info: Title: Huge variation in obtaining ethical permission for a non-interventional observational study in Europe Author: Dylan W. de Lange Subject: BMC Medical Ethics, 2019, doi:10.1186/s12910-019-0373-y Keywords: Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Fri May 31 13:09:25 CEST 2019 ModDate: Mon Jun 03 17:16:24 CEST 2019 ID: 0x40807397cea2239e6b95b917aa9b5798, 0x9672f01947795b585cd702105789503a Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 33 ImageHeight: 63 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -46, -250, 1126, 879 FontFile: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HsghftHelvetica FirstChar: 32 LastChar: 122 FontDescriptor: FontName: HsghftHelvetica Flags: Nonsymbolic FontBBox: -166, -225, 1000, 931 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBDK+XwgqjwAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: OPFBDK+XwgqjwAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFCHK+NbwnrpAdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: OPFCHK+NbwnrpAdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBLK+FjtktbAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: OPFBLK+FjtktbAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBLL+KcftpxAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 78 FontDescriptor: FontName: OPFBLL+KcftpxAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFCHL+QmsgtnAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 112 FontDescriptor: FontName: OPFCHL+QmsgtnAdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBIJ+CfnvwxAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: OPFBIJ+CfnvwxAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBLM+KlbwrpAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: OPFBLM+KlbwrpAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFCFJ+VxnjdqAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: OPFCFJ+VxnjdqAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFDCL+VcbcshAdvTTb5929f4c+22 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: OPFDCL+VcbcshAdvTTb5929f4c+22 Flags: Symbolic FontBBox: -10, -218, 1083, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OPFDDM+DxsbxvAdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: OPFDDM+DxsbxvAdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFBJK+CvtycwAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: OPFBJK+CvtycwAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFCPL+TxtktqAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: OPFCPL+TxtktqAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OPFCIM+DgdbnfAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: OPFCIM+DgdbnfAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding XMP: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) application/pdf 10.1186/s12910-019-0373-y BMC Medical Ethics BMC Medical Ethics, 2019, doi:10.1186/s12910-019-0373-y Huge variation in obtaining ethical permission for a non-interventional observational study in Europe Dylan W. de Lange Bertrand Guidet Finn H. Andersen Antonio Artigas Guidio Bertolini Rui Moreno Steffen Christensen Maurizio Cecconi Christina Agvald-Ohman Primoz Gradisek Christian Jung Brian J. Marsh Sandra Oeyen Bernardo Bollen Pinto Wojciech Szczeklik Ximena Watson Tilemachos Zafeiridis Hans Flaatten 2019-06-03T17:16:24+02:00 2019-05-31T19:09:25+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode 2019-06-03T17:16:24+02:00 uuid:bbdcae84-f74f-4796-a03b-60e2bc8ea674 uuid:54497264-e186-4cb0-a59c-b26827dfe94c default 1 converted uuid:4ca00935-2ae0-4e99-928f-52d74a1595a2 converted to PDF/A-2b pdfToolbox 2019-05-31T19:16:50+08:00 2 B Dylan W. de Lange http://orcid.org/0000-0002-0191-7270 Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx PDF/X ID Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 496, 635, 538, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 143, 573, 151, 582 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 411, 167, 415, 177 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 461, 143, 465, 153 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 239, 65, 357, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 182, 41, 321, 48 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 117, 197, 125 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 118, 585, 123, 594 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 89, 525, 94, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 232, 285, 237, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 152, 57, 157, 66 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 470, 141, 475, 150 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 260, 129, 265, 138 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 402, 57, 407, 66 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 59, 285, 64, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 70, 285, 75, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 461, 357, 466, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 396, 297, 406, 306 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 91, 525, 101, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 235, 477, 245, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 417, 69, 426 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 76, 417, 86, 426 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 526, 681, 536, 690 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 304, 669, 314, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 373, 597, 383, 606 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 388, 597, 397, 606 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 6 Thumb: true Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 203, 574, 283, 581 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 565, 111, 572 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 81, 538, 202, 545 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 131, 519, 228, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 206, 465, 274, 472 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 456, 124, 463 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 125, 438, 228, 445 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 140, 410, 273, 418 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 123, 356, 255, 363 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 328, 179, 336 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 301, 276, 309 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 292, 85, 300 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 212, 274, 280, 281 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 265, 118, 272 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 226, 238, 277, 245 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 229, 140, 236 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 187, 165, 288, 172 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 156, 90, 163 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 222, 92, 289, 100 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 83, 113, 91 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 483, 684, 534, 692 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 675, 370, 683 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 386, 648, 506, 656 Flags: Print AppearanceDictionary: true Thumb: true Checksum: eb92cd4c Type: CRC32 Checksum: 49e2269278f8caeda70766010bca4132 Type: MD5 Checksum: bc8d1a5c041a04ff5ef2680579d30e89ad319ed8 Type: SHA-1