f696d03ede82e1a735384d378355eba2  226577.pdf
8b0ec1c68a2bfba17f27cb8f066d22580b410848  226577.pdf
a5b65bb8952f681eb4a965fd2459ae855d32f60456abbf8174e389806897c629  226577.pdf

Title:          Prediction of Progression-Free Survival in Patients With Advanced, Well-Differentiated, Neuroendocrine Tumors Being Treated With a Somatostatin Analog: The GETNE-TRASGU Study
Subject:        JCO 2019.37:2571-2580
Author:         Alberto Carmona-Bayonas, Paula Jiménez-Fonseca, Ángela Lamarca, Jorge Barriuso, Ángel Castaño, Marta Benavent, Vicente Alonso, María del Carmen Riesco-Martínez, Teresa Alonso-Gordoa, Ana Custodio, Manuel Sánchez Cánovas, Jorge Hernando Cubero, Carlos López, Adelaida Lacasta, Ana Fernández Montes, Mónica Marazuela, Guillermo Crespo, Pilar Escudero, José Ángel Diaz, Eduardo Feliciangeli, Javier Gallego, Marta Llanos, Ángel Segura, Felip Vilardell, Juan Carlos Percovich, Enrique Grande, Jaume Capdevila, Juan W. Valle, and Rocío García-Carbonero
Creator:        Arbortext Advanced Print Publisher 9.1.510/W Unicode
Producer:       Acrobat Distiller 10.0.0 (Windows); modified using iText 4.2.0 by 1T3XT
CreationDate:   Fri Sep  6 04:11:23 2019 CEST
ModDate:        Thu Feb 17 15:09:44 2022 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          11
Encrypted:      no
Page size:      584.957 x 782.986 pts
Page rot:       0
File size:      961755 bytes
Optimized:      yes
PDF version:    1.5


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MBLNNB+AdvTT4350c63d                 Type 1C           WinAnsi          yes yes no     388  0
MBLNNC+AdvOTb03e4648.B               Type 1C           WinAnsi          yes yes no     390  0
MBLNND+AdvOT8a0d451b.B               Type 1C           WinAnsi          yes yes no     392  0
MBLNNE+AdvOT8a0d451b.B+01            Type 1C           MacRoman         yes yes no     394  0
MBLNNF+AdvOTd710a12c                 Type 1C           WinAnsi          yes yes no     396  0
MBLNNG+AdvOTd710a12c+fb              Type 1C           Custom           yes yes yes    399  0
MBLODF+AdvOT53f3fec7                 Type 1C           WinAnsi          yes yes no     401  0
MBLODG+AdvOT53f3fec7+fb              Type 1C           Custom           yes yes yes    404  0
Times-Roman                          Type 1            WinAnsi          no  no  no     413  0
MBLOND+AdvOTd710a12c+20              Type 1C           WinAnsi          yes yes no     214  0
MBLOPE+AdvOT463cc31e                 Type 1C           WinAnsi          yes yes no     216  0
MBLOPF+AdvOT8817665d                 Type 1C           WinAnsi          yes yes no     219  0
MBLOPG+AdvPS7DA6                     Type 1C           WinAnsi          yes yes no     215  0
MBLPAG+AdvOTa82dc243.I               Type 1C           WinAnsi          yes yes no     220  0
MBLPDG+Univers                       Type 1C           Custom           yes yes no     230  0
MBLPEH+Helvetica-Bold                Type 1C           WinAnsi          yes yes no     229  0
MBLPEI+Univers-Condensed             Type 1C           WinAnsi          yes yes no     227  0
MBMAAE+AdvOT72cf81eb.BI              Type 1C           WinAnsi          yes yes no     231  0
MBMADF+Univers-Oblique               Type 1C           WinAnsi          yes yes no     232  0
MBMADE+SymbolMT                      CID TrueType      Identity-H       yes yes yes    233  0
MBMAPC+AdvOT53f3fec7+01              Type 1C           MacRoman         yes yes no     238  0
MBMAPD+AdvOT53f3fec7+20              Type 1C           WinAnsi          yes yes no     237  0
MBMBBD+AdvOTd710a12c+01              Type 1C           Custom           yes yes no     240  0
MBMBCE+AdvPSUnvNCp                   Type 1C           WinAnsi          yes yes no     242  0
MBMBDE+AdvOTb03e4648.B+20            Type 1C           WinAnsi          yes yes no     244  0
MBMBDF+AdvOT8a0d451b.B+20            Type 1C           WinAnsi          yes yes no     243  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2022-02-18 02:36:33 CET
 RepresentationInformation: 226577.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2022-02-17 15:38:11 CET
  Size: 961755
  Format: PDF
  Version: 1.5
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B11' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B12' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B13' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B14' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B15' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B16' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B17' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B18' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B19' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B20' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B21' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B22' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B23' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B24' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B25' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B26' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B24' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B27' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B22' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B28' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B31' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B32' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B34' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B35' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B36' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B37' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found
   Offset: 954224
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B38' cannot be found
   Offset: 954224
  ID: PDF-HUL-129
  InfoMessage: Outlines contain recursive references.
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 0
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Prediction of Progression ...
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d
      Children: 
       Item: 
        Title: INTRODUCTION
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89
       Item: 
        Title: PATIENTS AND METHODS
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9
        Children: 
         Item: 
          Title: Study Population and Design
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e
         Item: 
          Title: Objectives and Variables of Interest
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b
         Item: 
          Title: Statistics
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b
       Item: 
        Title: RESULTS
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31
        Children: 
         Item: 
          Title: Patients and Treatments
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107
         Item: 
          Title: Outcomes
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e
         Item: 
          Title: Development of a Predictive Model of PFS
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7
         Item: 
          Title: External Validation
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e
       Item: 
        Title: DISCUSSION
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247
       Item: 
        Title: REFERENCES
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9
       Item: 
        Title: REFERENCES
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36
   Filters: 
    FilterPipeline: FlateDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type0: 
     Font: 
      BaseFont: MBMADE+SymbolMT
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: MBLPEI+Univers-Condensed
      FontSubset: true
      FirstChar: 32
      LastChar: 122
      FontDescriptor: 
       FontName: MBLPEI+Univers-Condensed
       Flags: Nonsymbolic
       FontBBox: -166, -250, 1000, 989
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLNNB+AdvTT4350c63d
      FontSubset: true
      FirstChar: 97
      LastChar: 116
      FontDescriptor: 
       FontName: MBLNNB+AdvTT4350c63d
       Flags: Serif, Nonsymbolic
       FontBBox: -31, -302, 895, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLPEH+Helvetica-Bold
      FontSubset: true
      FirstChar: 65
      LastChar: 68
      FontDescriptor: 
       FontName: MBLPEH+Helvetica-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -170, -228, 1003, 962
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLNNC+AdvOTb03e4648.B
      FontSubset: true
      FirstChar: 37
      LastChar: 169
      FontDescriptor: 
       FontName: MBLNNC+AdvOTb03e4648.B
       Flags: Nonsymbolic
       FontBBox: -52, -218, 927, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLPDG+Univers
      FontSubset: true
      FirstChar: 21
      LastChar: 121
      FontDescriptor: 
       FontName: MBLPDG+Univers
       Flags: Nonsymbolic
       FontBBox: -168, -250, 992, 947
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: MBMAAE+AdvOT72cf81eb.BI
      FontSubset: true
      FirstChar: 80
      LastChar: 80
      FontDescriptor: 
       FontName: MBMAAE+AdvOT72cf81eb.BI
       Flags: Nonsymbolic
       FontBBox: -52, -270, 1072, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLNND+AdvOT8a0d451b.B
      FontSubset: true
      FirstChar: 44
      LastChar: 241
      FontDescriptor: 
       FontName: MBLNND+AdvOT8a0d451b.B
       Flags: Nonsymbolic
       FontBBox: -31, -218, 895, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBMADF+Univers-Oblique
      FontSubset: true
      FirstChar: 118
      LastChar: 118
      FontDescriptor: 
       FontName: MBMADF+Univers-Oblique
       Flags: Nonsymbolic, Italic
       FontBBox: -174, -250, 1145, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLNNE+AdvOT8a0d451b.B+01
      FontSubset: true
      FirstChar: 245
      LastChar: 245
      FontDescriptor: 
       FontName: MBLNNE+AdvOT8a0d451b.B+01
       Flags: Nonsymbolic
       FontBBox: 0, -187, 916, 906
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: MBLNNF+AdvOTd710a12c
      FontSubset: true
      FirstChar: 37
      LastChar: 241
      FontDescriptor: 
       FontName: MBLNNF+AdvOTd710a12c
       Flags: Nonsymbolic
       FontBBox: -31, -208, 895, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBMAPD+AdvOT53f3fec7+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: MBMAPD+AdvOT53f3fec7+20
       Flags: Nonsymbolic
       FontBBox: -166, -135, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBMAPC+AdvOT53f3fec7+01
      FontSubset: true
      FirstChar: 245
      LastChar: 245
      FontDescriptor: 
       FontName: MBMAPC+AdvOT53f3fec7+01
       Flags: Nonsymbolic
       FontBBox: 0, -187, 958, 895
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: MBLNNG+AdvOTd710a12c+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: MBLNNG+AdvOTd710a12c+fb
       Flags: Symbolic
       FontBBox: 0, 0, 500, 729
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MBMBBD+AdvOTd710a12c+01
      FontSubset: true
      FirstChar: 183
      LastChar: 245
      FontDescriptor: 
       FontName: MBMBBD+AdvOTd710a12c+01
       Flags: Nonsymbolic
       FontBBox: 0, -177, 958, 885
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      BaseFont: MBLODF+AdvOT53f3fec7
      FontSubset: true
      FirstChar: 40
      LastChar: 241
      FontDescriptor: 
       FontName: MBLODF+AdvOT53f3fec7
       Flags: Nonsymbolic
       FontBBox: -10, -218, 947, 958
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBMBCE+AdvPSUnvNCp
      FontSubset: true
      FirstChar: 110
      LastChar: 110
      FontDescriptor: 
       FontName: MBMBCE+AdvPSUnvNCp
       Flags: Nonsymbolic
       FontBBox: 0, -218, 989, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBMBDF+AdvOT8a0d451b.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: MBMBDF+AdvOT8a0d451b.B+20
       Flags: Nonsymbolic
       FontBBox: -166, -145, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLODG+AdvOT53f3fec7+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MBLODG+AdvOT53f3fec7+fb
       Flags: Symbolic
       FontBBox: 0, 0, 500, 729
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MBMBDE+AdvOTb03e4648.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: MBMBDE+AdvOTb03e4648.B+20
       Flags: Nonsymbolic
       FontBBox: -166, -145, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLOND+AdvOTd710a12c+20
      FontSubset: true
      FirstChar: 145
      LastChar: 151
      FontDescriptor: 
       FontName: MBLOND+AdvOTd710a12c+20
       Flags: Nonsymbolic
       FontBBox: -166, -145, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLOPG+AdvPS7DA6
      FontSubset: true
      FirstChar: 98
      LastChar: 98
      FontDescriptor: 
       FontName: MBLOPG+AdvPS7DA6
       Flags: Nonsymbolic
       FontBBox: -20, -208, 1000, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLOPE+AdvOT463cc31e
      FontSubset: true
      FirstChar: 44
      LastChar: 46
      FontDescriptor: 
       FontName: MBLOPE+AdvOT463cc31e
       Flags: Nonsymbolic
       FontBBox: -20, -239, 989, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLOPF+AdvOT8817665d
      FontSubset: true
      FirstChar: 36
      LastChar: 36
      FontDescriptor: 
       FontName: MBLOPF+AdvOT8817665d
       Flags: Nonsymbolic
       FontBBox: -20, -208, 1000, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MBLPAG+AdvOTa82dc243.I
      FontSubset: true
      FirstChar: 80
      LastChar: 118
      FontDescriptor: 
       FontName: MBLPAG+AdvOTa82dc243.I
       Flags: Nonsymbolic
       FontBBox: -52, -270, 1041, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
    CIDFontType2: 
     Font: 
      BaseFont: MBMADE+SymbolMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: MBMADE+SymbolMT
       Flags: Symbolic
       FontBBox: 0, -220, 1113, 1005
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.6-c015 91.163280, 2018/06/22-11:31:03        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:prism="http://prismstandard.org/namespaces/basic/2.1/"
            xmlns:crossmark="http://crossref.org/crossmark/1.0/"
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1200/JCO.19.00980</dc:identifier>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Alberto Carmona-Bayonas, Paula Jiménez-Fonseca, Ángela Lamarca, Jorge Barriuso, Ángel Castaño, Marta Benavent, Vicente Alonso, María del Carmen Riesco-Martínez, Teresa Alonso-Gordoa, Ana Custodio, Manuel Sánchez Cánovas, Jorge Hernando Cubero, Carlos López, Adelaida Lacasta, Ana Fernández Montes, Mónica Marazuela, Guillermo Crespo, Pilar Escudero, José Ángel Diaz, Eduardo Feliciangeli, Javier Gallego, Marta Llanos, Ángel Segura, Felip Vilardell, Juan Carlos Percovich, Enrique Grande, Jaume Capdevila, Juan W. Valle, and Rocío García-Carbonero</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">JCO 2019.37:2571-2580</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Prediction of Progression-Free Survival in Patients With Advanced, Well-Differentiated, Neuroendocrine Tumors Being Treated With a Somatostatin Analog: The GETNE-TRASGU Study</rdf:li>
            </rdf:Alt>
         </dc:title>
         <prism:doi>10.1200/JCO.19.00980</prism:doi>
         <prism:url>https://doi.org/10.1200/JCO.19.00980</prism:url>
         <crossmark:MajorVersionDate>2019-08-07</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1200/JCO.19.00980</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>ascopubs.org</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:doi>10.1200/JCO.19.00980</pdfx:doi>
         <pdfx:CrossmarkMajorVersionDate>2019-08-07</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>ascopubs.org</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <xmp:CreateDate>2019-09-06T07:41:23+05:30</xmp:CreateDate>
         <xmp:CreatorTool>Arbortext Advanced Print Publisher 9.1.510/W Unicode</xmp:CreatorTool>
         <xmp:ModifyDate>2022-02-17T15:09:44+01:00</xmp:ModifyDate>
         <xmp:MetadataDate>2022-02-17T15:09:44+01:00</xmp:MetadataDate>
         <pdf:Producer>Acrobat Distiller 10.0.0 (Windows); modified using iText 4.2.0 by 1T3XT</pdf:Producer>
         <xmpMM:DocumentID>uuid:7ef51a29-4545-435d-8260-a1a59a11a5b9</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:aef8d9bf-76ef-42d8-a7f9-341959000f1e</xmpMM:InstanceID>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 226, 100, 229, 108
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 229, 76, 232, 84
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 358, 127, 362, 135
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 364, 127, 368, 135
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 428, 76, 432, 84
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 434, 76, 438, 84
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 36, 196, 89, 203
      Annotation: 
       Subtype: Link
       Rect: 36, 102, 58, 110
      Annotation: 
       Subtype: Link
       Rect: 70, 92, 103, 100
      Annotation: 
       Subtype: Link
       Rect: 36, 82, 100, 90
      Annotation: 
       Subtype: Link
       Rect: 36, 72, 57, 80
      Annotation: 
       Subtype: Link
       Rect: 482, 769, 582, 747
     Thumb: true
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 250, 588, 253, 597
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 255, 588, 258, 597
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 304, 419, 307, 427
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 159, 359, 166, 367
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 269, 322, 273, 331
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 274, 322, 281, 331
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 117, 221, 124, 229
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 126, 221, 133, 229
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 300, 197, 307, 205
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 188, 112, 195, 120
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 347, 733, 354, 742
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 347, 721, 354, 730
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 356, 721, 363, 730
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 519, 470, 522, 479
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 524, 470, 531, 479
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 532, 470, 539, 479
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 521, 383, 528, 391
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 373, 359, 380, 367
       Destination: null
     Thumb: true
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 505, 343, 512, 352
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 514, 343, 521, 352
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 355, 307, 362, 316
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 337, 248, 344, 256
       Destination: null
     Thumb: true
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 259, 300, 266, 309
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 190, 252, 197, 261
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 195, 205, 202, 213
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 239, 193, 245, 201
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 247, 193, 254, 201
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 256, 193, 263, 201
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 222, 108, 253, 117
       Destination: 8
      Annotation: 
       Subtype: Link
       Rect: 487, 315, 548, 325
       Destination: 23
      Annotation: 
       Subtype: Link
       Rect: 317, 303, 329, 313
       Destination: 23
      Annotation: 
       Subtype: Link
       Rect: 393, 184, 456, 193
       Destination: 23
     Thumb: true
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 225, 729, 254, 739
       Destination: 32
      Annotation: 
       Subtype: Link
       Rect: 77, 717, 110, 727
       Destination: 40
      Annotation: 
       Subtype: Link
       Rect: 80, 682, 107, 691
       Destination: 40
      Annotation: 
       Subtype: Link
       Rect: 373, 705, 392, 715
       Destination: 52
      Annotation: 
       Subtype: Link
       Rect: 358, 694, 525, 703
     Thumb: true
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 228, 646, 255, 655
       Destination: 40
      Annotation: 
       Subtype: Link
       Rect: 340, 610, 344, 618
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 345, 610, 352, 618
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 544, 450, 548, 459
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 367, 411, 371, 419
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 539, 375, 542, 383
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 544, 375, 548, 383
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 521, 327, 524, 335
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 467, 315, 474, 323
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 513, 267, 520, 275
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 522, 267, 529, 275
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 480, 243, 487, 252
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 496, 160, 503, 168
       Destination: null
     Thumb: true
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 122, 464, 129, 473
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 408, 464, 411, 473
       Destination: 70
      Annotation: 
       Subtype: Link
       Rect: 514, 365, 517, 373
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 256, 521, 281, 529
       Destination: 32
     Thumb: true
    Page: 
     Label: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 218, 148, 224, 156
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 101, 112, 108, 120
       Destination: null
     Thumb: true
    Page: 
     Label: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 217, 266, 301, 273
      Annotation: 
       Subtype: Link
       Rect: 77, 256, 111, 263
      Annotation: 
       Subtype: Link
       Rect: 469, 586, 548, 594
      Annotation: 
       Subtype: Link
       Rect: 317, 577, 366, 584
     Thumb: true
    Page: 
     Label: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 203, 438, 365, 445
      Annotation: 
       Subtype: Link
       Rect: 180, 355, 337, 362
      Annotation: 
       Subtype: Link
       Rect: 307, 333, 519, 340
      Annotation: 
       Subtype: Link
       Rect: 198, 322, 366, 329
     Thumb: true
    Page: 
     Label: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 222, 682, 275, 688
      Annotation: 
       Subtype: Link
       Rect: 285, 682, 356, 688
     Thumb: true
  Checksum: e07d0c16
   Type: CRC32
  Checksum: f696d03ede82e1a735384d378355eba2
   Type: MD5
  Checksum: 8b0ec1c68a2bfba17f27cb8f066d22580b410848
   Type: SHA-1