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Circles are molecules which Docetaxel binds to, resulting in an alterat:71' cannot be found Offset: 1798579 MIMEtype: application/pdf PDFMetadata: Objects: 522 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetax ... Children: Item: Title: Results Children: Item: Title: miR-210-3p is overexpressed in tumour samples as compared with normal breast tissues from reductive mammoplasty. Item: Title: miR-210-3p up-regulation is more frequent in triple negative breast cancer. Item: Title: Evaluation of miR-210–3p prognostic value in breast cancer cases. Item: Title: High miR-210-3p expression can predict early metastases development and death in patients treated with epirubicin-cyclofosf ... Item: Title: In silico prediction of miR-210-3p and docetaxel cross-talk. Item: Title: Discussion Item: Title: Conclusions Item: Title: Materials and Methods Children: Item: Title: Design, setting and eligibility criteria. Children: Item: Title: Patients and treatment. Item: Title: RNA isolation and RT-qPCR for miRNA detection. Item: Title: Statistical analysis. Item: Title: Bioinformatic analyses. Item: Title: Ethics approval and consent to participate. Item: Title: Acknowledgements Item: Title: Figure 1 Prognostic ability of miR-210-3p expression in predicting survival outcomes in patients treated with Epirubicin-Ciclofosfamide and Docetaxel regimen. Item: Title: Figure 2 Identification of common molecules among miR-210-3p targets and Docetaxel interactors. Item: Title: Table 1 Association between miR-210-3p expression and time-to-event outcomes according to adjuvant chemotherapy schemes. Item: Title: Table 2 Improvement in prognostic ability from clinical Cox models (which included: pathological stage, grade, HER2/neu, estrogen receptor and progesterone receptor as clinical covariates) to extended Cox models, which included the covariates stated above Info: Title: Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel Author: Barbara Pasculli Subject: Scientific Reports, doi:10.1038/s41598-019-51581-3 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Thu Oct 10 21:30:40 CEST 2019 ModDate: Fri Oct 11 15:48:30 CEST 2019 ID: 0x4a1c578cec52563224c547a7caf65c69, 0x3adf1e19dfaee26df2b40a3b079567c7 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2000 ImageHeight: 1062 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: 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US Scientific Reports, doi:10.1038/s41598-019-51581-3 Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel Barbara Pasculli Raffaela Barbano Michelina Rendina Andrea Fontana Massimiliano Copetti Tommaso Mazza Vanna Maria Valori Maria Morritti Evaristo Maiello Paolo Graziano Roberto Murgo Vito Michele Fazio Manel Esteller Paola Parrella 10.1038/s41598-019-51581-3 http://dx.doi.org/10.1038/s41598-019-51581-3 journal Scientific Reports © 2019, The Author(s) 2045-2322 10.1038/s41598-019-51581-3 Springer 2019-10-11T15:48:30+02:00 2019-10-11T00:30:40+05:30 2019-10-11T15:48:30+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) VoR uuid:4fc4ac78-849b-4f21-a9fc-dd2901c255dc uuid:63ca7709-3b99-4bdb-8fd5-c1ad1eb1220d default 1 converted uuid:1ba8058a-2b9d-4143-9a7b-6239088dddaa converted to PDF/A-2b pdfToolbox 2019-10-11T00:31:36+05:30 2 B http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal 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PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. 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