860b44159ea84910dfa9eee86bd630c6  285807.pdf
9c0882a43c442e4c46387d242210e98cdcf6acee  285807.pdf
17168157fd86861f0805984c01675a45a121823ecd0987ad23b0d59a961b91bc  285807.pdf

Title:          
Subject:        
Keywords:       The JAMA Network
Author:         American Medical Association
Creator:        XPP
Producer:       ; modified using iTextSharp 4.1.6 by 1T3XT
CreationDate:   Tue Aug 27 12:23:08 2019 CEST
ModDate:        Mon Dec 11 10:47:08 2023 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          10
Encrypted:      no
Page size:      612 x 792 pts (letter)
Page rot:       0
File size:      808952 bytes
Optimized:      no
PDF version:    1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MPGJNC+GuardianSans-RegularIt        Type 1C           Custom           yes yes yes     35  0
MPGJNB+GuardianSansGR-Regular        Type 1C           Custom           yes yes yes     36  0
MPGJNA+GuardianSans-Medium           Type 1C           Custom           yes yes yes     37  0
MPGJMP+GuardianSans-Semibold         Type 1C           Custom           yes yes yes     38  0
RZTJTM+ArialMT                       TrueType          WinAnsi          yes yes no       1  0
MPGKHP+MathematicalPi-One            Type 1C           Custom           yes yes no      81  0
MPGKOO+GuardianAgateSansGR-Medium    Type 1C           Custom           yes yes yes     97  0
MPGKNN+GuardianAgateSans1GR-Regular  Type 1C           Custom           yes yes yes     98  0
MPGLDN+GuardianAgateSans-MediumIt    Type 1C           Custom           yes yes yes    113  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2023-12-12 02:36:56 CET
 RepresentationInformation: 285807.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2023-12-11 11:57:31 CET
  Size: 808952
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 199
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Info: 
    Title: 
    Author: American Medical Association
    Subject: 
    Keywords: The JAMA Network
    Creator: XPP
    Producer: ; modified using iTextSharp 4.1.6 by 1T3XT
    CreationDate: Tue Aug 27 12:23:08 CEST 2019
    ModDate: Mon Dec 11 10:47:08 CET 2023
   ID: 0xb207062f48092139dff622b31bb87a3a, 0x3eaf7ac193e6495c37118219bfa59441
   Filters: 
    FilterPipeline: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: MPGKHP+MathematicalPi-One
      FontSubset: true
      FirstChar: 2
      LastChar: 3
      FontDescriptor: 
       FontName: MPGKHP+MathematicalPi-One
       Flags: Symbolic
       FontBBox: -30, -210, 1000, 779
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: MPGKOO+GuardianAgateSansGR-Medium
      FontSubset: true
      FirstChar: 32
      LastChar: 122
      FontDescriptor: 
       FontName: MPGKOO+GuardianAgateSansGR-Medium
       Flags: Symbolic
       FontBBox: -260, -204, 1070, 1036
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGLDN+GuardianAgateSans-MediumIt
      FontSubset: true
      FirstChar: 80
      LastChar: 80
      FontDescriptor: 
       FontName: MPGLDN+GuardianAgateSans-MediumIt
       Flags: Symbolic, Italic
       FontBBox: -319, -204, 1060, 1036
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGKNN+GuardianAgateSans1GR-Regular
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: MPGKNN+GuardianAgateSans1GR-Regular
       Flags: Symbolic
       FontBBox: -250, -204, 1063, 1036
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGJNC+GuardianSans-RegularIt
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: MPGJNC+GuardianSans-RegularIt
       Flags: Symbolic, Italic
       FontBBox: -217, -217, 1106, 1061
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGJNB+GuardianSansGR-Regular
      FontSubset: true
      FirstChar: 37
      LastChar: 243
      FontDescriptor: 
       FontName: MPGJNB+GuardianSansGR-Regular
       Flags: Symbolic
       FontBBox: -175, -217, 1194, 1061
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGJNA+GuardianSans-Medium
      FontSubset: true
      FirstChar: 40
      LastChar: 122
      FontDescriptor: 
       FontName: MPGJNA+GuardianSans-Medium
       Flags: Symbolic
       FontBBox: -180, -219, 1240, 1072
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MPGJMP+GuardianSans-Semibold
      FontSubset: true
      FirstChar: 43
      LastChar: 124
      FontDescriptor: 
       FontName: MPGJMP+GuardianSans-Semibold
       Flags: Symbolic
       FontBBox: -185, -222, 1277, 1082
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: RZTJTM+ArialMT
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: RZTJTM+ArialMT
       Flags: Nonsymbolic
       FontBBox: -664, -324, 2000, 1039
       FontFile2: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 4.2.1-c043 52.372728, 2009/01/18-15:08:04        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords>The JAMA Network</pdf:Keywords>
      <Producer>; modified using iTextSharp 4.1.6 by 1T3XT</Producer></rdf:Description>
      <rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:creator>
            <rdf:Seq>
               <rdf:li>American Medical Association</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:ModifyDate>2023-12-11T09:47:08+00:00</xmp:ModifyDate>
         <xmp:CreatorTool>XPP</xmp:CreatorTool>
         <xmp:CreateDate>2019-08-27T10:23:08Z</xmp:CreateDate>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 430, 243, 504, 253
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 225, 631, 280, 643
      Annotation: 
       Subtype: Link
       Rect: 180, 607, 294, 616
      Annotation: 
       Subtype: Link
       Rect: 151, 93, 188, 105
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 142, 464, 186, 475
      Annotation: 
       Subtype: Link
       Rect: 46, 295, 91, 306
      Annotation: 
       Subtype: Link
       Rect: 60, 269, 104, 280
      Annotation: 
       Subtype: Link
       Rect: 116, 178, 161, 190
    Page: 
     Label: 4
    Page: 
     Label: 5
    Page: 
     Label: 6
    Page: 
     Label: 7
    Page: 
     Label: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 155, 453, 277, 463
      Annotation: 
       Subtype: Link
       Rect: 279, 439, 324, 449
      Annotation: 
       Subtype: Link
       Rect: 141, 403, 216, 413
    Page: 
     Label: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 284, 344, 366, 354
      Annotation: 
       Subtype: Link
       Rect: 303, 319, 377, 329
      Annotation: 
       Subtype: Link
       Rect: 46, 308, 69, 318
      Annotation: 
       Subtype: Link
       Rect: 58, 272, 174, 282
      Annotation: 
       Subtype: Link
       Rect: 91, 236, 146, 246
      Annotation: 
       Subtype: Link
       Rect: 107, 211, 188, 221
      Annotation: 
       Subtype: Link
       Rect: 193, 186, 280, 196
      Annotation: 
       Subtype: Link
       Rect: 90, 161, 178, 171
      Annotation: 
       Subtype: Link
       Rect: 231, 136, 311, 146
      Annotation: 
       Subtype: Link
       Rect: 289, 112, 391, 121
      Annotation: 
       Subtype: Link
       Rect: 46, 101, 367, 111
      Annotation: 
       Subtype: Link
       Rect: 46, 90, 136, 100
    Page: 
     Label: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 330, 724, 387, 734
      Annotation: 
       Subtype: Link
       Rect: 46, 713, 283, 723
      Annotation: 
       Subtype: Link
       Rect: 337, 688, 391, 698
      Annotation: 
       Subtype: Link
       Rect: 46, 677, 338, 687
      Annotation: 
       Subtype: Link
       Rect: 46, 666, 104, 676
      Annotation: 
       Subtype: Link
       Rect: 256, 641, 340, 651
      Annotation: 
       Subtype: Link
       Rect: 264, 616, 312, 626
      Annotation: 
       Subtype: Link
       Rect: 167, 580, 250, 590
      Annotation: 
       Subtype: Link
       Rect: 350, 556, 375, 565
      Annotation: 
       Subtype: Link
       Rect: 46, 545, 119, 555
      Annotation: 
       Subtype: Link
       Rect: 145, 509, 239, 519
      Annotation: 
       Subtype: Link
       Rect: 279, 484, 330, 494
      Annotation: 
       Subtype: Link
       Rect: 343, 448, 385, 458
      Annotation: 
       Subtype: Link
       Rect: 46, 437, 86, 447
      Annotation: 
       Subtype: Link
       Rect: 151, 401, 254, 411
      Annotation: 
       Subtype: Link
       Rect: 275, 365, 357, 375
      Annotation: 
       Subtype: Link
       Rect: 207, 329, 292, 339
      Annotation: 
       Subtype: Link
       Rect: 370, 315, 381, 325
      Annotation: 
       Subtype: Link
       Rect: 46, 304, 106, 314
      Annotation: 
       Subtype: Link
       Rect: 84, 279, 140, 289
  Checksum: dcb509d1
   Type: CRC32
  Checksum: 860b44159ea84910dfa9eee86bd630c6
   Type: MD5
  Checksum: 9c0882a43c442e4c46387d242210e98cdcf6acee
   Type: SHA-1
  Checksum: 17168157fd86861f0805984c01675a45a121823ecd0987ad23b0d59a961b91bc
   Type: SHA-256