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A position paper by the European Conference on Infections in Leukemia (ECIL) Subject: Leukemia, doi:10.1038/s41375-019-0388-x Keywords: Author: Georg Maschmeyer Creator: Springer CreationDate: Tue Mar 19 04:46:51 2019 CET ModDate: Tue Mar 19 04:48:11 2019 CET Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 19 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 844020 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KPDGOI+AdvOT5fcf1b24 Type 1C WinAnsi yes yes no 1047 0 KPDGOJ+AdvOT5fcf1b24+20 Type 1C WinAnsi yes yes no 1042 0 KPDGOK+AdvOTce3d9a73 Type 1C WinAnsi yes yes no 1043 0 KPDHFJ+AdvOTc20ddc96 Type 1C WinAnsi yes yes no 1051 0 KPDHJI+AdvOT8608a8d1+25 Type 1C Custom yes yes yes 1053 0 KPDHNI+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 1054 0 KPDHNJ+AdvOTf9433e2d Type 1C WinAnsi yes yes no 1055 0 KPDHOJ+AdvOTf9433e2d+fb Type 1C Custom yes yes yes 1059 0 KPDHOK+AdvTT4ff65459 Type 1C WinAnsi yes yes no 1060 0 KPDIGI+AdvOTf9433e2d+20 Type 1C WinAnsi yes yes no 418 0 KPDIHJ+AdvOT35387326.B Type 1C WinAnsi yes yes no 417 0 KPDINI+AdvTTab7e17fd+22 Type 1C Custom yes yes no 425 0 KPDIOI+AdvTTab7e17fd Type 1C WinAnsi yes yes no 424 0 KPDJEH+AdvOTf9433e2d+03 Type 1C Custom yes yes yes 444 0 KPDJFI+AdvOTf9433e2d+22 Type 1C Custom yes yes yes 443 0 KPDJFJ+AdvOTb4af3d5d.I Type 1C WinAnsi yes yes no 446 0 KPDLCP+AdvOT8608a8d1+03 Type 1C Custom yes yes yes 567 0 KPDNAE+AdvOTc20ddc96+fb Type 1C Custom yes yes yes 669 0 KPDNDE+AdvOTc20ddc96+20 Type 1C WinAnsi yes yes no 686 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2023-12-16 02:33:33 CET RepresentationInformation: 286288.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-12-15 11:04:01 CET Size: 844020 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1125 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by’the European Conference on Infections in Leukemia (ECIL) Destination: title_link Children: Item: Title: Abstract Destination: A1 Item: Title: Introduction Destination: A2 Item: Title: Methods Destination: A3 Item: Title: Immunotherapeutic agents (blinatumomab, brentuximab vedotin, immune checkpoint inhibitors): characterization, impact on immunity, reported infectious complications and recommendations for clinical practice Destination: A4 Children: Item: Title: Blinatumomab Destination: B1 Item: Title: Brentuximab vedotin Destination: B2 Item: Title: Immune checkpoint inhibitors Destination: B3 Item: Title: Molecular targeted agents (ibrutinib, idelalisib, HDAC inhibitors, mTOR inhibitors, ruxolitinib, venetoclax): characterization, impact on immunity, reported infectious complications and recommendations for clinical practice Destination: A5 Children: Item: Title: Ibrutinib Destination: B4 Item: Title: Idelalisib Destination: B5 Item: Title: Histone deacetylase (HDAC) inhibitors (panobinostat, vorinostat, romidepsin) Destination: B6 Item: Title: mTOR inhibitors (sirolimus, temsirolimus, everolimus) Destination: B7 Item: Title: Ruxolitinib Destination: B8 Item: Title: Venetoclax Destination: B9 Item: Title: Compliance with ethical standards Destination: B10 Item: Title: ACKNOWLEDGMENTS Destination: M1 Item: Title: ACKNOWLEDGMENTS Destination: M1 Item: Title: References Destination: A6 Info: Title: Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. 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doi:10.1038/s41375-019-0388-x Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections in Leukemia (ECIL) Georg Maschmeyer Julien Greef Sibylle C. Mellinghoff Annamaria Nosari Anne Thiebaut-Bertrand Anne Bergeron Tomas Franquet Nicole M. A. Blijlevens Johan A. Maertens Springer US Leukemia, doi:10.1038/s41375-019-0388-x 10.1038/s41375-019-0388-x http://dx.doi.org/10.1038/s41375-019-0388-x journal Leukemia © 2019, The Author(s) 1476-5551 10.1038/s41375-019-0388-x springer.com springerlink.com 2010-04-23 True 10.1038/s41375-019-0388-x springer.com springerlink.com Springer 2019-03-19T09:18:11+05:30 2019-03-19T09:16:51+05:30 2019-03-19T09:18:11+05:30 True VoR uuid:3539c002-c03b-4973-89a4-f247cf90deaa uuid:bf2daf73-993d-4162-8a94-4f48e227d8b9 default 1 converted uuid:3493093e-6c4e-42f0-8a31-b38f9309a40c converted to PDF/A-2b pdfToolbox 2019-03-19T09:18:11+05:30 2 B Georg Maschmeyer http://orcid.org/0000-0003-2378-2466 Julien Greef http://orcid.org/0000-0003-0200-1237 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. 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